Keyphrases
Phosphorylation
100%
Parkin
89%
Parkinson's Disease
75%
Phosphorylated Ubiquitin
54%
Ubiquitin
44%
PTEN-induced Kinase 1 (PINK1)
43%
Protein Kinase
37%
E3 Ubiquitin Ligase
29%
Phosphoserine
23%
Niclosamide
21%
Anthelmintic Drugs
21%
Genetic Encoding
21%
Mitochondrial Architecture
21%
Biochemical Characterization
21%
Tribolium Castaneum
21%
Disease-related Proteins
21%
Rab GTPase
21%
Nonhydrolyzable Analog
21%
Quality Control
21%
Mitophagy
21%
Structural Characterization
21%
Disease-causing mutations
21%
Downstream Targets
21%
Semi-synthetic
21%
Phosphoproteomics
21%
Ubiquitylation
21%
MITOS
21%
Autosomal Recessive Early-onset Parkinson's Disease
14%
E3 Ligase Activity
14%
Phosphorylation Sites
14%
Mitochondria
12%
Mitochondrial Depolarization
11%
Orthogonal Pair
10%
Engineered E. Coli
10%
Amber Stop Codon
10%
Aminoacyl-tRNA Synthetase
10%
NEK7
10%
Protein Phosphorylation
10%
Analytical Method
10%
Biologically Relevant
10%
Serine Phosphorylation
10%
Biological Processes
10%
Genetically Encoded
10%
Recombinant Protein
10%
Post-translational Modification
10%
Escherichia Coli
10%
Site-specific Incorporation
10%
Protein Function
10%
Activation Loop
10%
Phosphorylated Protein
10%
Ubiquitin-like
9%
Rab8a
7%
E3 Ligase
7%
Bowl Shape
7%
Three-loop
7%
Mitochondrial Signaling
7%
Binding Site
7%
Loss Function
7%
Mitochondrial Membrane Potential
7%
Related Disorders
7%
Therapeutic Strategies
7%
Kinase Activity
7%
Encoded Protein
7%
Idiopathic Parkinson's Disease
7%
Primary Neurons
7%
Small Molecule Modulators
7%
Neurodegenerative Diseases
7%
Mitochondrial Dysfunction
7%
Unknown Function
7%
Neurodegeneration
7%
Signal Process
7%
Autophosphorylation
7%
Major Contributor
7%
Kinase Domain
7%
Novel Biomarkers
6%
Crystal Form
6%
Biochemistry, Genetics and Molecular Biology
PINK1
78%
Ubiquitin
75%
Kinase
53%
Phosphotransferase
53%
Serine
50%
Protein Kinases
25%
Phosphoserine
23%
Enzyme
21%
Ubiquitin-Conjugating Enzyme
21%
Quality Control
21%
Phosphoproteomics
21%
Mitophagy
21%
Escherichia coli
21%
Genetics
21%
Ligase
20%
Parkin (Ligase)
12%
Quantitative Technique
10%
Aminoacyl tRNA Synthetase
10%
Cell Extract
10%
Recombinant Protein
10%
Biological Phenomena and Functions Concerning the Entire Organism
10%
Analytical Method
10%
Protein Phosphorylation
10%
Posttranslational Modification
10%
Phosphoprotein
10%
Stop Codon
10%
Autosomal Recessive Inheritance
9%
Tribolium castaneum
7%
Neuroscience
Parkin
65%
Parkinson's Disease
51%
Protein Kinases
30%
Ubiquitin Protein Ligase E3
29%
Kinase
29%
Ubiquitin
25%
Serine
21%
Anthelmintic
21%
Niclosamide
21%
Ubiquitination
21%
Parkinson Disease Associated Protein
21%
Ligase
10%
Mitochondrion
8%
Neurodegenerative Disorder
7%
Familial Parkinson's Disease
7%
Mitochondrial Membrane Potential
7%
Neurodegeneration
7%
In Vitro
6%