Research output per year
Research output per year
Research output
- 9 Article
Search results
-
2018
The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1
Barini, E., Miccoli, A., Tinarelli, F., Mulholland, K., Kadri, H., Khanim, F., Stojanovski, L., Read, K. D., Burness, K., Blow, J. J., Mehellou, Y. (Lead / Corresponding author) & Muqit, M. M. K. (Lead / Corresponding author), 2 Mar 2018, In: ChemBioChem. 19, 5, p. 425-429 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Citations (Scopus)240 Downloads (Pure) -
2017
Structure of PINK1 and mechanisms of Parkinson's disease associated mutations
Kumar, A., Tamjar, J., Waddell, A. D., Woodroof, H. I., Raimi, O. G., Shaw, A. M., Peggie, M., Muqit, M. M. K. (Lead / Corresponding author) & van Aalten, D. M. F. (Lead / Corresponding author), 9 Nov 2017, In: eLife. 6, p. 1-16 16 p., e29985.Research output: Contribution to journal › Article › peer-review
Open AccessFile75 Citations (Scopus)309 Downloads (Pure) -
2016
mito-QC illuminates mitophagy and mitochondrial architecture in vivo
McWilliams, T., Prescott, A., Allen, G., Tamjar, J., Munson, M., Thomson, C., Muqit, M. & Ganley, I. (Lead / Corresponding author), 25 Jul 2016, In: Journal of Cell Biology. 214, 3, p. 333-345 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile366 Citations (Scopus)514 Downloads (Pure) -
Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation
Pao, K. C., Stanley, M., Han, C., Lai, Y. C., Murphy, P., Balk, K., Wood, N. T., Corti, O., Corvol, J. C., Muqit, M. M. K. & Virdee, S. (Lead / Corresponding author), May 2016, In: Nature Chemical Biology. 12, 5, p. 324-331 8 p.Research output: Contribution to journal › Article › peer-review
87 Citations (Scopus) -
2015
A versatile strategy for the semisynthetic production of Ser65 phosphorylated ubiquitin and its biochemical and structural characterisation
Han, C., Pao, K.-C., Kazlauskaite, A., Muqit, M. M. K. & Virdee, S. (Lead / Corresponding author), 27 Jul 2015, In: ChemBioChem. 16, 11, p. 1574-1579 6 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation
Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. M. (Lead / Corresponding author), 1 Aug 2015, In: EMBO Reports. 16, 8, p. 939-954 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile189 Citations (Scopus)276 Downloads (Pure) -
Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog
Rogerson, D. T., Sachdeva, A., Wang, K., Haq, T., Kazlauskaite, A., Hancock, S. M., Huguenin-Dezot, N., Muqit, M. M. K., Fry, A. M., Bayliss, R. & Chin, J. W. (Lead / Corresponding author), Jul 2015, In: Nature Chemical Biology. 11, 7, p. 496-503 8 p.Research output: Contribution to journal › Article › peer-review
188 Citations (Scopus) -
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1
Lai, Y.-C., Kondapalli, C., Lehneck, R., Procter, J. B., Dill, B. D., Woodroof, H. I., Gourlay, R., Peggie, M., Macartney, T. J., Corti, O., Corvol, J.-C., Campbell, D. G., Itzen, A., Trost, M. (Lead / Corresponding author) & Muqit, M. M. (Lead / Corresponding author), 12 Nov 2015, In: EMBO Journal. 34, 22, p. 2840-2861 22 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile142 Citations (Scopus)154 Downloads (Pure) -
PINK1 and Parkin - mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease
Kazlauskaite, A. & Muqit, M. M. K. (Lead / Corresponding author), Jan 2015, In: FEBS Journal. 282, 2, p. 215-223 9 p.Research output: Contribution to journal › Article › peer-review
Open Access87 Citations (Scopus)