Study of Differential TRNA Post-Transcriptional Modifications as a Mechanism to Control Proteome Composition

Project Details

StatusFinished
Effective start/end date31/03/14 → 30/03/17

Funding

  • Biotechnology and Biological Sciences Research Council (BB/L008874/1): £325,784.00
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Research Output

Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase

Munoz, I., Morgan, M., Peltier, J., Weiland, F., Gregorczyk, M., Brown, F. C. M., Macartney, T., Toth, R., Trost, M. & Rouse, J., 14 Dec 2018, In : The EMBO Journal. 37, 24, p. 1-19 19 p., e99559.

Research output: Contribution to journal › Article

Open Access
File
    • 11 Citations (Scopus)
    208 Downloads (Pure)

    Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib

    Miettinen, T. P., Peltier, J., Härtlova, A., Gierliński, M., Jansen, V. M., Trost, M. & Björklund, M., 15 May 2018, In : EMBO Journal. 37, 10, p. 1-19 19 p., e98359.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 25 Citations (Scopus)
    219 Downloads (Pure)

    Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation

    Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. MK., 1 Aug 2015, In : EMBO Reports. 16, 8, p. 939-954 16 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 91 Citations (Scopus)
    143 Downloads (Pure)