Research output
- 7 Article
Search results
-
2018
Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase
Munoz, I., Morgan, M., Peltier, J., Weiland, F., Gregorczyk, M., Brown, F. C. M., Macartney, T., Toth, R., Trost, M. (Lead / Corresponding author) & Rouse, J. (Lead / Corresponding author), 14 Dec 2018, In: The EMBO Journal. 37, 24, p. 1-19 19 p., e99559.Research output: Contribution to journal › Article › peer-review
Open AccessFile61 Citations (Scopus)409 Downloads (Pure) -
Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib
Miettinen, T. P., Peltier, J., Härtlova, A., Gierliński, M., Jansen, V. M., Trost, M. (Lead / Corresponding author) & Björklund, M. (Lead / Corresponding author), 15 May 2018, In: EMBO Journal. 37, 10, p. 1-19 19 p., e98359.Research output: Contribution to journal › Article › peer-review
Open AccessFile92 Citations (Scopus)432 Downloads (Pure) -
2015
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation
Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. M. (Lead / Corresponding author), 1 Aug 2015, In: EMBO Reports. 16, 8, p. 939-954 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile212 Citations (Scopus)352 Downloads (Pure) -
Protein degradation and dynamic tRNA thiolation fine-tune translation at elevated temperatures
Tyagi, K. & Pedrioli, P. G. A. (Lead / Corresponding author), 19 May 2015, In: Nucleic Acids Research. 43, 9, p. 4701-4712 12 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Citations (Scopus) -
2014
Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction
van der Wijst, J. (Lead / Corresponding author), Blanchard, M. G., Woodroof, H. I., Macartney, T. J., Gourlay, R., Hoenderop, J. G., Bindels, R. J. & Alessi, D. R. (Lead / Corresponding author), 13 May 2014, In: Biochemical Journal. 460, 2, p. 165-175 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)213 Downloads (Pure) -
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
Kazlauskaite, A., Kelly, V., Johnson, C., Baillie, C., Hastie, C. J., Peggie, M., Macartney, T., Woodroof, H. I., Alessi, D. R., Pedrioli, P. G. A. & Muqit, M. M. K., 19 Mar 2014, In: Open Biology. 4, 14 p., 130213.Research output: Contribution to journal › Article › peer-review
119 Citations (Scopus) -
VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase
Baron, Y., Pedrioli, P. G., Tyagi, K., Johnson, C., Wood, N. T., Fountaine, D., Wightman, M. & Alexandru, G. (Lead / Corresponding author), May 2014, In: BMC Biology. 12, 20 p., 39.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)252 Downloads (Pure)