Temperature Responsive Control of Splicing by RNA Methylation (Joint with University of Leeds)

Simpson, Gordon (Investigator)

Plant Sciences

Status	Active
Effective start/end date	19/09/22 → 18/09/25

Funding

Biotechnology and Biological Sciences Research Council (BB/W007673/1): £363,689.00

3 Article

U6 snRNA m6A modification is required for accurate and efficient splicing of C. elegans and human pre-mRNAs
Shen, A., Hencel, K., Parker, M. T., Scott, R., Skukan, R., Adesina, A. S., Metheringham, C. L., Miska, E. A., Nam, Y., Haerty, W., Simpson, G. G. & Akay, A. (Lead / Corresponding author), 27 Aug 2024, In: Nucleic Acids Research. 52, 15, p. 9139-9160 22 p.
Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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Inter-species association mapping links splice site evolution to METTL16 and SNRNP27K
Parker, M. T., Fica, S. M., Barton, G. J. & Simpson, G. G. (Lead / Corresponding author), 17 Oct 2023, In: eLife. 12, 25 p., e91997.
Research output: Contribution to journal › Article › peer-review

Open Access
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5 Citations (Scopus)

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m⁶A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site
Parker, M. T., Soanes, B. K., Kusakina, J., Larrieu, A., Knop, K., Joy, N., Breidenbach, F., Sherwood, A. V., Barton, G. J., Fica, S. M., Davies, B. H. (Lead / Corresponding author) & Simpson, G. G. (Lead / Corresponding author), 30 Dec 2022, In: eLife. 11, 34 p., e78808.
Research output: Contribution to journal › Article › peer-review

Open Access
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24 Citations (Scopus)

125 Downloads (Pure)