Research output per year
Research output per year
Search results
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2021
Ankyrin repeats in context with human population variation
Utgés, J. S., Tsenkov, M. I., Dietrich, N. J. M., MacGowan, S. A. & Barton, G. J. (Lead / Corresponding author), 30 May 2021, BioRxiv, 26 p.Research output: Working paper/Preprint › Preprint
Open AccessFile133 Downloads (Pure) -
Effects of common mutations in the SARS-CoV-2 Spike RBD domain and its ligand the human ACE2 receptor on binding affinity and kinetics
Barton, M. I., MacGowan, S., Kutuzov, M., Dushek, O., Barton, G. J. (Lead / Corresponding author) & Merwe, P. A. V. D. (Lead / Corresponding author), 24 May 2021, BioRxiv, 39 p.Research output: Working paper/Preprint › Preprint
File191 Downloads (Pure) -
Missense variants in human ACE2 modify binding to SARS-CoV-2 Spike
MacGowan, S. A., Barton, M. I. (Lead / Corresponding author), Kutuzov, M., Dushek, O., Merwe, P. A. V. D. & Barton, G. J., 21 May 2021, BioRxiv, 28 p.Research output: Working paper/Preprint › Preprint
File149 Downloads (Pure) -
2020
Missense variants in ACE2 are predicted to encourage and inhibit interaction with SARS-CoV-2 Spike and contribute to genetic risk in COVID-19
MacGowan, S. A. (Lead / Corresponding author) & Barton, G. J. (Lead / Corresponding author), 4 May 2020, Cold Spring Harbor Laboratory: BioRxiv, 38 p.Research output: Working paper/Preprint › Preprint
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2017
Human Missense Variation is Constrained by Domain Structure and Highlights Functional and Pathogenic Residues
MacGowan, S., Madeira, F., Britto Borges, T., Schmittner, M. S., Cole, C. & Barton, G., 13 Apr 2017, Cold Spring Harbor Laboratory: BioRxiv, 35 p.Research output: Working paper/Preprint › Preprint
File606 Downloads (Pure)