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Keyphrases
Obesity
70%
Cluster of Differentiation 44 (CD44)
62%
Extracellular Matrix
51%
Matrix Expansion
41%
Myocardial Insulin Resistance
41%
Myocardial Remodeling
41%
Diet-induced Obese Mice
41%
Cell Surface Receptor
41%
Metabolic Disorders
41%
Extracellular Matrix Remodeling
41%
O-linked N-acetylglucosamine (O-GlcNAc)
41%
Diabetic Nephropathy
41%
O-GlcNAc Modification
41%
Therapeutic Target
41%
Adipogenesis
41%
Related Pathway
41%
Hyaluronan-mediated Motility Receptor
41%
Hepatic Oxidative Stress
41%
Hyaluronan
33%
Extracellular Matrix Protein 1 (ECM1)
32%
Insulin Resistance
29%
Extracellular Matrix Deposition
28%
Collagen
28%
Protein O-GlcNAcylation
27%
Obese Mice
23%
Adhesome
20%
Fibrosis
20%
Integrin Receptor
20%
O-GlcNAcylation
20%
Obesity Treatment
16%
Insulin Sensitivity
16%
Therapeutic Potential
15%
Renal Interstitial Fibrosis
13%
Kidney Cells
13%
Cell Surface
13%
High-fat Diet
11%
PEGPH20
11%
Pirfenidone
11%
Cardiac Tissue
11%
Re-expression
11%
Causes of Obesity
10%
Cardiometabolic Complications
10%
Tissue Metabolism
10%
Metabolic Dysfunction
10%
Cell Signaling
10%
Matrix Cell
10%
Undernutrition
10%
Glycoprotein
10%
Growth Factors
10%
Complex Networks
10%
Cytokine Factors
10%
Signaling Molecules
10%
Catalytic Activity
10%
Molecular Mechanism
10%
Specific Interactions
10%
Ligand-specific
10%
Extracellular Environment
10%
Specific Action
10%
Matrix Polysaccharides
10%
Cell number
10%
Serious Pathology
10%
Pathophysiological Mechanisms
10%
Signaling Cascades
10%
Adhesion Proteins
10%
Parvin
10%
Cell Adhesion Proteins
10%
Matrix Protein
10%
Receptor-mediated
10%
Metabolic Effects
10%
Receptor-ligand Interaction
10%
Preadipocytes
8%
Adipocyte
8%
Current Treatment
6%
Disease Progression
6%
Renal Cell
6%
Hexosamine Pathway
6%
Hyperglycemia
6%
Sodium-glucose Cotransporter 2 Inhibitors (SGLT2i)
6%
Renal Tubular Epithelial Cells
6%
UDP-GlcNAc
6%
Kidney Injury
6%
Renin-angiotensin-aldosterone System Inhibitors
6%
Narrative Review
6%
Podocyte
6%
Glucose Flux
6%
Cell Damage
6%
Protein Post-translational Modification
6%
Aminotransferase
6%
Mesangial Cells
6%
Fructose
6%
Obesity Prevention
5%
Disease Clusters
5%
Functional Change
5%
Genomic Deletion
5%
Cardiac Dysfunction
5%
Resistance Diseases
5%
Pharmacological Approaches
5%
Cardiac Function
5%
Matrix metalloproteinase-9 (MMP-9)
5%
Recombinant Hyaluronidase
5%
Cardiac Extracellular Matrix
5%
Tight
5%
Novel Therapeutics
5%
In Vivo Analysis
5%
Diet-induced
5%
Hyperinsulinemic-euglycemic Clamp
5%
Genetic Approach
5%
Heart Disease
5%
Collagen Expression
5%
Insulin Action
5%
PEGylated
5%
Pressure-volume Loop Analysis
5%
Mouse Model
5%
C57BL
5%
Collagen Deposition
5%
Antifibrotic
5%
Cardiovascular Complications
5%
Protein Nitration
5%
Hepatic Antioxidants
5%
Loop Analysis
5%
Biochemistry, Genetics and Molecular Biology
CD44
100%
Insulin Resistance
71%
Restylane
55%
Cell Cycle
41%
Mouse Mutant
41%
Adipogenesis
41%
Cell Surface Receptor
41%
Peroxisome Proliferator-Activated Receptor
41%
Kidney Function
41%
Heart Performance
41%
Integrin
27%
Heart Function
25%
Creatinine Blood Level
20%
Mineralocorticoid Receptor
20%
Renin Angiotensin Aldosterone System
20%
C57BL 6 Mouse
15%
Growth Factor
13%
Polysaccharide
13%
Cytokine
13%
Cell Adhesion Proteins
13%
Tissue Metabolism
13%
Glycoprotein
13%
Enzymatic Activity
13%
Adhesion Protein
13%
Matrix Protein
13%
Preadipocyte
10%
Adipocyte
10%
Heart Ejection Fraction
10%
Heart Output
10%
Interleukin 6
10%
Protein Kinase B
10%
Receptor Antagonist
10%
Fat Mass
10%
Tau
10%
Blood Pressure
10%
Gene Deletion
7%
Mouse Model
5%
Hyaluronidase
5%
Recombinant
5%
Disease Classification
5%
Gelatinase B
5%
MMP9
5%
Insulin Sensitivity
5%
Genetics
5%
Protein Carbonylation
5%
Pharmacology, Toxicology and Pharmaceutical Science
Hyaluronic Acid
65%
Receptor
55%
Cell Surface Receptor
41%
Mouse Mutant
41%
N Acetylglucosamine
41%
Thyrotropin
41%
Diabetic Nephropathy
41%
Eplerenone
41%
Fibrosis
27%
Integrin Receptor
27%
Insulin Resistance
27%
Cytokine
18%
Aldosterone
17%
Angiotensin
17%
Renin
17%
Transcription Factor Nrf2
15%
Cerebrovascular Accident
15%
Diseases
13%
Overnutrition
13%
Matrix Protein
13%
Glycoprotein
13%
Growth Factor
13%
Polysaccharide
13%
Cell Receptor
13%
Fibrosing Alveolitis
13%
Cell Adhesion Proteins
13%
Inflammation
10%
Thyroid Disease
10%
Reduced Nicotinamide Adenine Dinucleotide (Phosphate) Dehydrogenase (Quinone)
10%
Kidney Hypertrophy
10%
Creatinine
10%
Hyperglycemia
6%
Disease Exacerbation
6%
Fructose
6%
sodium glucose cotransporter-2 inhibitors
6%
Hexosamine
6%
Uridine Diphosphate
6%
Kidney Injury
6%
Aminotransferase
6%
Hypothyroidism
5%
Antioxidant
5%
Protein Kinase B
5%
Tumor Necrosis Factor
5%
Interleukin 1
5%
Interleukin 6
5%
Mineralocorticoid Receptor
5%
Elevated Blood Pressure
5%
Kidney Fibrosis
5%
Mineralocorticoid Antagonist
5%
C57BL 6 Mouse
5%