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The Innovative Targets Portfolio: Basic Life Sciences Research to Novel Therapies, through a Portfolio of Small Molecule Translational Projects
Ferguson, Michael
(Investigator)
Gray, David
(Investigator)
Wyatt, Paul
(Investigator)
Drug Discovery Unit
Overview
Fingerprint
Research Outputs
(3)
Research output
Research output per year
2021
2021
2021
3
Article
Research output per year
Research output per year
3 results
Publication Year, Title
(descending)
Publication Year, Title
(ascending)
Title
Type
Search results
2021
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
Armstrong, L. A.,
Lange, S. M.
,
de Cesare, V.
,
Matthews, S. P.
,
Nirujogi, R. S.
, Cole, I., Hope, A.,
Cunningham, F.
,
Toth, R.
, Mukherjee, R., Bojkova, D., Gruber, F.,
Gray, D.
, Wyatt, P. G., Cinatl, J., Dikic, I.,
Davies, P.
&
Kulathu, Y.
(Lead / Corresponding author),
16 Jul 2021
,
In:
PLoS ONE.
16
,
7
,
25 p.
, e0253364.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Biochemical Characterization
100%
Protease Activity
100%
COVID-19
100%
Nanobody
100%
Nsp3
100%
60
Citations (Scopus)
167
Downloads (Pure)
Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7 Methyltransferase Using RapidFire Mass Spectrometry
Pearson, L.-A.
,
Green, C.
,
Lin, D.
,
Petit, A.-P.
,
Gray, D.
(Lead / Corresponding author),
Cowling, V.
& Fordyce, E. (Lead / Corresponding author),
Jul 2021
,
In:
SLAS Discovery.
26
,
6
,
p. 749-756
8 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Guanine
100%
COVID-19
100%
High-throughput Screening Assays
100%
N7-methyltransferase
100%
RapidFire Mass Spectrometry
100%
28
Citations (Scopus)
138
Downloads (Pure)
Drug screening to identify compounds to act as co-therapies for the treatment of Burkholderia species
Barker, S., Harding, S. V.,
Gray, D.
, Richards, M. I., Atkins, H. S. & Harmer, N. J. (Lead / Corresponding author),
25 Mar 2021
,
In:
PLoS ONE.
16
,
3
,
18 p.
, e0248119.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Ceftazidime
100%
Drug Screening
100%
Co-therapy
100%
Burkholderia Species
100%
Chloroxine
100%
2
Citations (Scopus)
166
Downloads (Pure)