Keyphrases
HOIL-1L
88%
Ubiquitylation
79%
Ubiquitin
75%
E3 Ligase
62%
ABIN1
51%
Ester Bond
50%
Esters
50%
TLR Signaling
47%
ALPK1
47%
IRAK2
40%
ADP-heptose
34%
TAK1
34%
Liver Pathology
32%
Myddosome
32%
Threonine
31%
Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6)
30%
Macrophages
29%
Ubiquitin Chains
29%
Immune Cells
28%
Knock-in Mouse Model
28%
Signaling Network
28%
IRAK4 Inhibitor
27%
Toll-like Receptor 7 (TLR7)
27%
Cytokine Production
26%
Coordinated Control
23%
CIAP1
23%
LUBAC
23%
ROSAH Syndrome
23%
Protein Kinase Activity
23%
Polyglucosan
23%
Lysine Ubiquitination
23%
Interleukin-18 (IL-18)
23%
Cytotoxic T Cells
23%
Myeloid Cells
23%
Nigericin
23%
Lupus
23%
NLRP3 Inflammasome
23%
Glomerulonephritis
23%
TRAF2
23%
Nucleotide Sugars
23%
Ubiquitin Ligase Activity
23%
MyD88 Signaling
23%
TNF Receptor Associated Factor 6
23%
Ubiquitin Linkage
23%
Spiradenoma
23%
Patrolling Monocytes
15%
Autoimmunity
15%
Neutrophils
15%
Interleukin-6
14%
NOD-like Receptor Protein 3 (NLRP3)
14%
Lysine Residue
13%
Bone Marrow-derived Macrophages
12%
Protein Kinase
12%
Lys63
12%
Maltoheptaose
11%
Myeloid Differentiation Factor 88 (MyD88)
11%
IRAK4
11%
R848
11%
Inflammatory Monocytes
11%
Inflammatory Mediators
9%
TGN38
9%
Costimulation
9%
Kidney Pathology
9%
Trans-Golgi Network
9%
Wild Mice
9%
Drug Treatment
9%
Serum Levels
9%
1-form
9%
MET1
9%
Ubiquitin Binding
8%
Prolonged Stimulation
8%
Amino Group
7%
Non-canonical
7%
Proteome
7%
Molecular Mechanism
7%
Protein Post-translational Modification
7%
Intracellular Lipids
7%
Conjugation
7%
Cysteine
7%
Encoded Protein
7%
Monocyte-derived Dendritic Cells (MoDCs)
7%
Adaptive Immune Response
7%
IKK Complex
6%
Granulocyte Colony-stimulating Factor (G-CSF)
6%
Interferon-α (IFN-α)
6%
Interleukin-12 (IL-12)
6%
Splenomegaly
6%
Intermediate Domain
5%
Carboxylate
5%
Linear Ubiquitin Chain Assembly Complex
5%
Amino Acid Residues
5%
Proline
5%
Bond Formation
5%
FARSITE
5%
Isopeptide Bond
5%
Glycogen
5%
T Cells
5%
Linkage Type
5%
Activating Ligands
5%
Biochemistry, Genetics and Molecular Biology
Ubiquitin
100%
Ubiquitination
76%
Ligase
71%
Heptose
47%
Adenosine Diphosphate
47%
IRAK2
36%
TRAF6
32%
Macrophage
26%
Lysine
26%
Serine
25%
Threonine
25%
Ubiquitin Ligase
23%
Cytotoxic T Cell
23%
Gene Linkage
23%
TLR Signaling
23%
TLR7
23%
Interleukin 18
23%
TRAF2
23%
Nucleotide Sugar
23%
Mediator
10%
Protein Kinases
10%
Wild Type
10%
Granulocyte Macrophage Colony-Stimulating Factor
9%
Cytokine
9%
Interferon
9%
IRAK4
6%
Enzyme
6%
Binding Site
6%
Mannose
6%
Polysaccharide
5%
Esterification
5%
Glucan
5%
Immunology and Microbiology
TLR Signaling
47%
Macrophage
39%
Immunocompetent Cell
37%
Bone Marrow-Derived Macrophage
35%
Cytokine Production
29%
Interleukin 6
29%
Neutrophil Granulocyte
27%
Autoimmunity
26%
Cytotoxic T Cell
23%
Interleukin 18
23%
Tumor Necrosis Factor Receptor
23%
NLRP3 Inflammasome
23%
Knockout Mouse
23%
Ubiquitination
23%
Myeloid
23%
Glomerulonephritis
23%
Adaptive Immune System
23%
Dendritic Cell
23%
Cytokine
19%
Cytokine Release
15%
Secretion (Process)
13%
Co-Stimulation
11%
Granulocyte Macrophage Colony-Stimulating Factor
11%
Trans Golgi Network
11%
interferon
11%
Dispersion
11%
NETosis
11%
Cell Division
11%
TLR7
11%
Mediator
7%
Wild Type
7%
Amino Terminal Sequence
7%
Enzyme Active Site
7%
Genetic Transcription
5%
Interleukin 12
5%
T Cell
5%