Research output per year
Research output per year
Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 30/09/14 → 27/02/18 |
Funding
- Biotechnology and Biological Sciences Research Council (BB/L01923X/1): £318,080.00
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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Detection of thermal shift in cellular Keap1 by protein-protein interaction inhibitors using immunoblot- and fluorescence microplate-based assays
Dayalan Naidu, S., Dikovskaya, D., Moore, T. W. & Dinkova-Kostova, A. (Lead / Corresponding author), 17 Jun 2022, In: STAR Protocols. 3, 2, 17 p., 101265.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)323 Downloads (Pure) -
Phenyl Bis-Sulfonamide Keap1-Nrf2 Protein-Protein Interaction Inhibitors with an Alternative Binding Mode
Georgakopoulos, N., Talapatra, S., Dikovskaya, D., Dayalan Naidu, S., Higgins, M., Gatliff, J., Ayhan, A., Nikoloudaki, R., Schaap, M., Valko, K., Javid, F., Dinkova-Kostova, A. T., Kozielski, F. & Wells, G. (Lead / Corresponding author), 26 May 2022, In: Journal of Medicinal Chemistry. 65, 10, p. 7380-7398 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)151 Downloads (Pure) -
The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2
Dayalan Naidu, S., Suzuki, T., Dikovskaya, D., Knatko, E. V., Higgins, M., Sato, M., Novak, M., Villegas, J. A., Moore, T. W., Yamamoto, M. & Dinkova-Kostova, A. (Lead / Corresponding author), 21 Jan 2022, In: iScience. 25, 1, 19 p., 103703.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)148 Downloads (Pure)