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Keyphrases
Stemness
83%
PIK3CA
83%
Phosphoinositide 3-kinase (PI3K)
75%
Breast Cancer
69%
PI3K Signaling
57%
Genotype
55%
AKT Inhibitor
41%
Stem Cell Markers
38%
AKT Pathway
36%
AKT Inhibition
34%
Growth Factors
34%
Transcriptomics
33%
PI3K-AKT-mTOR Signaling
27%
Biochemical Systems
27%
Mitogen-activated Protein Kinase
27%
Pluripotent Stem Cells
27%
Breast Cancer Cells
27%
Homozygosity
27%
Self-sustaining
27%
Multi-omics Profiling
27%
Degrader
27%
TGF Signaling
27%
Synergize
27%
Statins
27%
Triple-negative Breast Cancer
27%
Cholesterol Biosynthesis
27%
Ligand Discrimination
27%
Signaling Specificity
27%
Corrupt
27%
Growth Factor Signaling
27%
Human Tumors
23%
PIK3CA mutation
20%
Reverse Phase Protein Array
19%
Human Breast Cancer
18%
Tumor Samples
18%
Signaling Network
18%
Breast Cancer Cell Lines
17%
Pitavastatin
17%
Human Pluripotent Stem Cells (hPSCs)
16%
Desensitization
16%
Information Transfer
16%
Non-equilibrium
16%
Allele Dosage
14%
Signal Strength
14%
Causal Network
13%
Array Measurements
13%
C-Jun N-terminal Kinase Signaling
13%
Therapeutic Window
13%
Hyperactivity
13%
C-Jun N-terminal Kinase
13%
Enhanced Efficacy
13%
Serine-threonine Kinase
13%
Network Integration
13%
Publicly Available
13%
Growth Inhibition
13%
Protein Kinase
13%
Signaling Effect
13%
Growth Inhibition Assay
13%
High Potency
13%
Network Applications
13%
Clinical Efficacy
13%
Cancer Cell Lines
13%
Computational Proteomics
13%
Tumor
13%
Receptor Degradation
11%
Dose Effect
11%
Cognate Ligand
11%
PI3K Pathway
10%
Hotspot mutation
9%
Linear Association
9%
Cellular Phenotype
9%
Patient Stratification
9%
Human Cell Models
9%
Dedifferentiation
9%
Multi-copy
9%
Aggressive Tumor
9%
Breast Tumor
9%
Selective Inhibitor
9%
Targeted Therapy
8%
Cellular Information Processing
6%
Control Principle
6%
Measurement Modeling
6%
Relay Networks
6%
Developmental Disorders
6%
Mathematical Modeling
6%
Metabolic Disease
6%
Disease-associated
6%
Signal Relay
6%
Common Cancers
6%
Underlying Network
6%
Biochemical Signaling
6%
Information Decision
6%
Time-resolved
6%
Breast Cancer Patients
6%
Niemann-Pick C1-like 1 (NPC1L1)
6%
Estrogen Receptor-positive Breast Cancer
6%
Sterol Regulatory Element Binding Protein 2
6%
Cholesterol Trafficking
6%
Cholesterol Homeostasis
6%
Artificial Systems
5%
Stemness Genes
5%
Human Cancer
5%
Disease-related
5%
Gene Expression
5%
Pharmacological Inhibitors
5%
Transcriptomic Signature
5%
Homozygous mutant
5%
Pathway Activation
5%
Pathway Inhibitors
5%
Proteomics
5%
Allele-specific Expression
5%
Non-associated
5%
Human Genetic Disease
5%
Overgrowth Syndrome
5%
Human Cervical Cancer
5%
Independent Cycles
5%
Biochemical Sensing
5%
Nonequilibrium Mechanism
5%
ERK Pathway
5%
Phosphoinositide 3-kinase Pathway
5%
Insulin Receptor Signaling
5%
Sensing Network
5%
Oncogene
5%
Reaction Pathway
5%
Preferential Amplification
5%
CyTOF
5%
Cellular Signaling Networks
5%
Sorting System
5%
Precise Calculation
5%
Signal Heterogeneity
5%
Noncognate
5%
Insulin-like
5%
Error Correction
5%
Thermodynamic Stability
5%
Specific Information
5%
Live Cell Imaging
5%
Therapeutic Benefits
5%
A1 Receptor
5%
Epidermal Growth Factor Signaling
5%
Ras-ERK
5%
Oncogenic Pathways
5%
Pathway mutation
5%
Signal Response
5%
Induced Pluripotent Stem Cells (iPSCs)
5%
Kinetic Proofreading
5%
Degradation Activity
5%
Multiplexing
5%
Epidermal Growth Factor Receptor Signaling
5%
Activity Patterns
5%
Biochemical Processes
5%
Receptor Activity
5%
Biochemistry, Genetics and Molecular Biology
Protein Kinase B
100%
Growth Factor
50%
Transcriptomics
44%
Carcinogenesis
34%
Cancer Cell
33%
Phosphoinositide 3-Kinase
33%
Decision Making
27%
Mitogen-Activated Protein Kinase
27%
mTOR Signaling
27%
Genotyping
27%
Biochemistry
27%
NODAL
27%
Stem Cell
27%
Homozygosity
27%
Cholesterol Synthesis
27%
Statin
27%
Epidermal Growth Factor
27%
Biochemical Process
27%
Metabolic Disorder
27%
Growth Factor Signaling
27%
Cellular Signalling Network
27%
Allele
19%
Pitavastatin
15%
Protein Microarray
9%
Proteomics
9%
Estrogen Receptor
9%
Kinase
7%
Phosphotransferase
7%
Human Genetics
6%
Genetic Disorder
6%
Gene Expression
6%
Sterol Regulatory Element Binding Protein 2
6%
Cholesterol Homeostasis
6%
Cell Dedifferentiation
5%
Preclinical Study
5%
Genetics
5%
Epidermal Growth Factor Receptor
5%
Cellular Imaging
5%
Insulin Receptor
5%
Insulin-Like Growth Factor 1 Receptor
5%
Induced Pluripotent Stem Cell
5%
Oncogene
5%
N-Terminus
5%
Growth Inhibition
5%
Medicine and Dentistry
Protein Kinase B
61%
Breast Cancer
58%
Neoplasm
50%
Statin
27%
Transcriptomics
27%
mTOR Signaling
27%
Cholesterol Synthesis
27%
Triple Negative Breast Cancer
27%
Pitavastatin
15%
Cell Dedifferentiation
11%
Malignant Neoplasm
11%
Allele
11%
Breast Tumor
11%
Targeted Therapy
8%
Phosphoinositide 3-Kinase
6%
Sterol Regulatory Element Binding Protein 2
6%
Organoid
6%
Cholesterol Homeostasis
6%
Signal Transduction
5%
Cell Signaling Pathway
5%