The Tayside Bioresource: Leveraging Electronic Medical Records to Deliver Personalised Medicine (Biomedical Resource Grant)

  • Colhoun, Helen (Investigator)
  • Connell, John (Investigator)
  • Doney, Alexander (Investigator)
  • Dow, Eleanor (Investigator)
  • Morris, Andrew (Investigator)
  • Palmer, Colin (Investigator)
  • Pearson, Ewan (Investigator)
  • Sullivan, Frank (Investigator)
  • Treweek, Shaun (Investigator)

Project Details

StatusFinished
Effective start/end date1/02/1331/10/15

Funding

  • Wellcome Trust (099177/Z/12/Z): £750,000.00

Research Output

Genetic mannose binding lectin deficiency is associated with airway microbiota diversity and reduced exacerbation frequency in COPD

Dicker, A. J., Crichton, M. L., Cassidy, A. J., Brady, G., Hapca, A., Tavendale, R., Einarsson, G. G., Furrie, E., Elborn, J. S., Schembri, S., Marshall, S. E., Palmer, C. N. A. & Chalmers, J. D., Jun 2018, In : Thorax. 73, 6, p. 510-518 9 p.

Research output: Contribution to journalArticle

Open Access
File
  • 12 Citations (Scopus)
    146 Downloads (Pure)

    Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease

    Yaghootkar, H., Lotta, L. A., Tyrrell, J., Smit, R. A. J., Jones, S. E., Donnelly, L., Beaumont, R., Campbell, A., Tuke, M. A., Hayward, C., Ruth, K. S., Padmanabhan, S., Jukema, J. W., Palmer, C. C., Hattersley, A., Freathy, R. M., Langenberg, C., Wareham, N. J., Wood, A. R., Murray, A. & 5 others, Weedon, M. N., Sattar, N., Pearson, E., Scott, R. A. & Frayling, T. M., Aug 2016, In : Diabetes. 65, 8, p. 2448-2460 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 40 Citations (Scopus)
    167 Downloads (Pure)

    Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion

    Yaghootkar, H., Stancáková, A., Freathy, R. M., Vangipurapu, J., Weedon, M. N., Xie, W., Wood, A. R., Ferrannini, E., Mari, A., Ring, S. M., Lawlor, D. A., Davey Smith, G., Jørgensen, T., Hansen, T., Pedersen, O., Steinthorsdottir, V., Guðbjartsson, D. F., Thorleifsson, G., Thorsteinsdottir, U., Stefansson, K. & 7 others, Hattersley, A. T., Walker, M., Morris, A. D., McCarthy, M. I., Palmer, C. N. A., Laakso, M. & Frayling, T. M., Jun 2015, In : Diabetes. 64, 6, p. 2279-2285 7 p.

    Research output: Contribution to journalArticle

  • 17 Citations (Scopus)