Towards a Unifying Theory of Parkinson's Disease - Investigation of the Biochemical and Genetic Role of Rab GTPases (joint with German Centre for Neurodegenerative Diseases)

Alessi, Dario (Investigator)
Muqit, Miratul (Investigator)

MRC PPU

Project Details

Status	Finished
Effective start/end date	17/10/16 → 16/10/18

Funding

Medical Research Council (MR/P00704X/1): £240,758.00

5 Article
1 Chapter (peer-reviewed)
1 Comment/debate

Advances in elucidating the function of leucine-rich repeat protein kinase-2 in normal cells and Parkinson's disease
Taylor, M. & Alessi, D., Apr 2020, In: Current Opinion in Cell Biology. 63, p. 102-113 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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15 Citations (Scopus)

152 Downloads (Pure)
Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2
Waschbüsch, D., Purlyte, E., Pal, P., McGrath, E., Alessi, D. R. & Khan, A. R., 7 Apr 2020, In: Structure. 28, 4, p. 406-417.e6 19 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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7 Citations (Scopus)

59 Downloads (Pure)
Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson’s disease kinase
Lis, P., Burel, S., Steger, M., Mann, M., Brown, F., Diez, F., Tonelli, F., Holton, J. L., Winglok Ho, P., Ho, S-L., Chou, M-Y., Polinski, N. K., Martinez, T. N., Davies, P. & Alessi, D. R., 2 Jan 2018, In: Biochemical Journal. 475, 1, p. 1-22 22 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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42 Citations (Scopus)

320 Downloads (Pure)