Research output per year
Research output per year
- 10 results
Search results
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2025
Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells
Sinclair, L. V. (Lead / Corresponding author), Youdale, T., Spinelli, L., Gakovic, M., Langlands, A. J., Pathak, S., Howden, A. J. M., Ganley, I. G. & Cantrell, D. A. (Lead / Corresponding author), 27 Feb 2025, In: Nature Immunology. 26, p. 429-443 32 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)4 Downloads (Pure) -
2024
A hydrophobic funnel governs monovalent cation selectivity in the ion channel TRPM5
Ives, C. M., Sahin, A. T., Thomson, N. J. & Zachariae, U. (Lead / Corresponding author), 1 Oct 2024, In: Biophysical Journal. 123, 19, p. 3304-3316 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile44 Downloads (Pure) -
Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy
Caldwell, N., Peet, C., Miller, P., Colon, B., Taylor, M., Cocco, M., Dawson, A., Lukac, I., Teixeira, J. E., Robinson, L., Frame, L., Seizova, S., Damerow, S., Tamaki, F., Post, J., Riley, J., Mutter, N., Hanna, J. C., Ferguson, L. & Hu, X. & 13 others, , 23 Oct 2024, In: Science Translational Medicine. 16, 770, p. 1-12 12 p., eadm8631.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)180 Downloads (Pure) -
Cryptosporidium Oocyst Wall Proteins are true oocyst wall proteins, with COWP8 functioning to hold the inner and outer layers of the oocyst wall together
Bacchetti, R., Stevens, S., Lemgruber, L., Oliva, M. A. G., Sands, E. M., Alexandrou, K., Tinti, M., Robinson, L., Hanna, J. C., Seizova, S., Goddard, P., Vassalli, M. & Pawlowic, M. C. (Lead / Corresponding author), 20 Jul 2024, BioRxiv, 22 p.Research output: Working paper/Preprint › Preprint
File8 Downloads (Pure) -
The molecular mechanism of monovalent cation selectivity in the TRPM5 channel
Ives, C. M. (Creator) & Zachariae, U. (Creator), 17 Jun 2024Research output: Non-textual form › Software
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2023
A cooperative knock-on mechanism underpins Ca2+-selective cation permeation in TRPV channels
Ives, C. M., Thomson, N. J. & Zachariae, U. (Lead / Corresponding author), 1 May 2023, In: Journal of General Physiology. 155, 5, 25 p., e202213226.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)151 Downloads (Pure) -
Mode of action studies confirm on-target engagement of lysyl-tRNA synthetase inhibitor and lead to new selection marker for Cryptosporidium
Hanna, J. C. .., Corpas Lopez, V., Seizova, S., Colon, B. L., Bacchetti, R., Hall, G. M. J., Sands, E. M., Robinson, L., Baragaña, B., Wyllie, S. (Lead / Corresponding author) & Pawlowic, M. (Lead / Corresponding author), 4 Aug 2023, In: Frontiers in Cellular and Infection Microbiology. 13, 14 p., 1236814.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)142 Downloads (Pure) -
Rhs NADase effectors and their immunity proteins are exchangeable mediators of interbacterial competition in Serratia
Hagan, M., Pankovs, G., Gallegos Monterrosa, R., Williams, D. J., Earl, C., Buchanan, G., Hunter, W. N. (Lead / Corresponding author) & Coulthurst, S. J. (Lead / Corresponding author), 28 Sept 2023, In: Nature Communications. 14, 16 p., 6061.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)128 Downloads (Pure) -
2022
Interactions between 2′-fluoro-(carbamoylpyridinyl)deschloroepibatidine analogues and acetylcholine-binding protein inform on potent antagonist activity against nicotinic receptors
Vieira Bueno, R., Davis, S., Dawson, A., Ondachi, P. W., Carroll, F. I. & Hunter, B. (Lead / Corresponding author), 1 Mar 2022, In: Acta Crystallographica Section D: Structural Biology. D78, Part 3, p. 353-362 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)71 Downloads (Pure) -
2019
Distinct signals and immune cells drive liver pathology and glomerulonephritis in ABIN1[D485N] mice
Nanda, S. K., Petrova, T., Marchesi, F., Gierlinski, M., Razsolkov, M., Lee, K. L., Wright, S. W., Rao, V. R., Cohen, P. (Lead / Corresponding author) & Arthur, J. S. C. (Lead / Corresponding author), 1 Dec 2019, In: Life Science Alliance. 2, 6, 19 p., e201900533.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)119 Downloads (Pure)