Research output per year
Research output per year
- 20 results
Search results
-
2024
The Atad5 RFC-like complex is the major unloader of proliferating cell nuclear antigen in Xenopus egg extracts
Kawasoe, Y. (Lead / Corresponding author), Shimokawa, S., Gillespie, P. J., Blow, J. J., Tsurimoto, T. & Takahashi, T. S. (Lead / Corresponding author), 16 Jan 2024, In: Journal of Biological Chemistry. 300, 1, 41 p., 105588.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)20 Downloads (Pure) -
2023
The location and development of Replicon Cluster Domains in early replicating DNA
Melo da Costa Nunes, J., Gierlinski, M., Sasaki, T., Haagensen, E. J., Gilbert, D. M. & Blow, J. J. (Lead / Corresponding author), 22 Aug 2023, In: Wellcome Open Research. 8, 42 p., 158.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)31 Downloads (Pure) -
2022
DDK: The Outsourced Kinase of Chromosome Maintenance
Gillespie, P. J. & Blow, J. J. (Lead / Corresponding author), 7 Jun 2022, In: Biology. 11, 6, 19 p., 877.Research output: Contribution to journal › Review article › peer-review
Open AccessFile9 Citations (Scopus)82 Downloads (Pure) -
2021
Development of BromoTag: A “Bump-&-Hole”-PROTAC system to induce potent, rapid, and selective degradation of tagged target proteins
Bond, A. G., Craigon, C., Chan, K. H., Testa, A., Karapetsas, A., Fasimoye, R., Macartney, T., Blow, J. J., Alessi, D. R. & Ciulli, A. (Lead / Corresponding author), 28 Oct 2021, In: Journal of Medicinal Chemistry. 64, 20, p. 15477-15502 26 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Citations (Scopus)212 Downloads (Pure) -
The role of DDK and Treslin-MTBP in coordinating replication licensing and pre-Initiation Complex formation
Volpi, I., Gillespie, P. J., Chadha, G. S. & Blow, J. (Lead / Corresponding author), Oct 2021, In: Open Biology. 11, 10, 18 p., 210121.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)113 Downloads (Pure) -
2020
3 tera-basepairs as a fundamental limit for robust DNA replication
Al Mamun, M. (Lead / Corresponding author), Albergante, L., Blow, J. J. & Newman, T. J. (Lead / Corresponding author), 30 Jun 2020, In: Physical Biology. 17, 4, 10 p., 046002.Research output: Contribution to journal › Article › peer-review
Open AccessFile77 Downloads (Pure) -
2019
Defects in the origin licensing checkpoint stresses cells exiting G0
Blow, J. J. (Lead / Corresponding author), 1 Jul 2019, In: Journal of Cell Biology. 218, 7, p. 2080-2081 2 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)118 Downloads (Pure) -
2018
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
Shoaib, M., Walter, D., Gillespie, P. J., Izard, F., Fahrenkrog, B., Lleres, D., Lerdrup, M., Johansen, J. V., Hansen, K., Julien, E., Blow, J. J. & Sørensen, C. S. (Lead / Corresponding author), 12 Sept 2018, In: Nature Communications. 9, 1, p. 1-11 11 p., 3704.Research output: Contribution to journal › Article › peer-review
Open AccessFile69 Citations (Scopus)207 Downloads (Pure) -
Lgr5+ intestinal stem cells reside in an unlicensed G1 phase
Carroll, T., Newton, I., Chen, Y., Blow, J. (Lead / Corresponding author) & Nathke, I. (Lead / Corresponding author), 7 May 2018, In: Journal of Cell Biology. 217, 5, p. 1667-1685 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (Scopus)276 Downloads (Pure) -
The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1
Barini, E., Miccoli, A., Tinarelli, F., Mulholland, K., Kadri, H., Khanim, F., Stojanovski, L., Read, K. D., Burness, K., Blow, J. J., Mehellou, Y. (Lead / Corresponding author) & Muqit, M. M. K. (Lead / Corresponding author), 2 Mar 2018, In: ChemBioChem. 19, 5, p. 425-429 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile41 Citations (Scopus)229 Downloads (Pure) -
2017
Reversal of DDK-mediated MCM phosphorylation by Rif1-PP1 regulates replication initiation and replisome stability independently of ATR/Chk1
Alver, R. C., Chadha, G. S., Gillespie, P. J. & Blow, J. J. (Lead / Corresponding author), 7 Mar 2017, In: Cell Reports. 18, 10, p. 2508-2520 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile83 Citations (Scopus)222 Downloads (Pure) -
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines
Gardner, N. J., Gillespie, P. J., Carrington, J. T., Shanks, E. J., McElroy, S. P., Haagensen, E. J., Frearson, J. A., Woodland, A. (Lead / Corresponding author) & Blow, J. J. (Lead / Corresponding author), 17 Aug 2017, In: Cell Chemical Biology. 24, 8, p. 981-992.e4 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)190 Downloads (Pure) -
2016
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing
Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F.-M., Gagos, S., Tzetis, M., Canovas, B., Igea, A., Ahuja, A. K., Zellweger, R., Havaki, S., Kanavakis, E., Kletsas, D., Roninson, I. B., Garbis, S. D. & Lopes, M. & 7 others, , Jul 2016, In: Nature Cell Biology. 18, 7, p. 777-789 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile227 Citations (Scopus)880 Downloads (Pure) -
Inevitability and containment of replication errors for eukaryotic genome lengths spanning Megabase to Gigabase
Al Mamun, M., Albergante, L., Moreno, A., Carrington, J. T., Blow, J. & Newman, T. J. (Lead / Corresponding author), 27 Sept 2016, In: Proceedings of the National Academy of Sciences. 113, 39, p. E5765-E5774 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)661 Downloads (Pure) -
The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability
Ho, T. L. F., Guilbaud, G., Blow, J. J., Sale, J. E. & Watson, C. J. (Lead / Corresponding author), 26 Apr 2016, In: Cell Reports. 15, 4, p. 724-734 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)184 Downloads (Pure) -
Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability
Lachaud, C., Moreno, A., Marchesi, F., Toth, R., Blow, J. J. & Rouse, J. (Lead / Corresponding author), 19 Feb 2016, In: Science. 351, 6275, p. 846-849 4 p.Research output: Contribution to journal › Article › peer-review
Open Access94 Citations (Scopus) -
Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells
Moreno, A., Carrington, J. T., Albergante, L., Al Mamun, M., Haagensen, E. J., Komseli, E.-S., Gorgoulis, V. G., Newman, T. J. & Blow, J. (Lead / Corresponding author), 27 Sept 2016, In: Proceedings of the National Academy of Sciences. 113, 39, p. E5757-E5764 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile86 Citations (Scopus)547 Downloads (Pure) -
2014
Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks
Albergante, L. (Lead / Corresponding author), Blow, J. J. (Lead / Corresponding author) & Newman, T. J. (Lead / Corresponding author), 2 Sept 2014, In: eLife. 3, 28 p., e02863.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)221 Downloads (Pure) -
The contribution of dormant origins to genome stability: from cell biology to human genetics
Alver, R. C., Chadha, G. S. & Blow, J. J. (Lead / Corresponding author), Jul 2014, In: DNA Repair. 19, p. 182-189 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile83 Citations (Scopus)288 Downloads (Pure) -
2013
Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts
Newman, T. J. (Lead / Corresponding author), Mamun, M. A., Nieduszynski, C. A. & Blow, J. J. (Lead / Corresponding author), Nov 2013, In: Nucleic Acids Research. 41, 21, p. 9705-9718 14 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus)