Keyphrases
Action Function
6%
Activating Transcription Factor 4 (ATF4)
21%
Adaptation
36%
Adaptation Responses
14%
Adaptive Response
7%
Adipose Tissue
11%
Adiposity
36%
Adult Male
7%
Adult Mice
7%
Aged Animals
7%
Aged Mice
14%
Aging
23%
Aging Skeletal muscle
7%
Amino Acid Starvation
36%
Amino Acid Transporter
7%
Amino Acids
29%
Anorectic Response
7%
Block System
7%
C57BL
7%
Caco-2 Cells
36%
Cannabinoid Receptor 1 (CB1R)
36%
Caveolin-3
36%
CB1 Receptor Blockade
36%
CDK7
36%
CDK7 Inhibitor
7%
Cell Behavior
10%
Cell Context
6%
Cell Function
14%
Cellular Adaptation
7%
Cellular Processes
6%
Cellular ROS
7%
Cellular Signaling Systems
10%
Critical Drivers
7%
Cyclin-dependent Kinase
7%
Cyclin-dependent Kinase Inhibitor
7%
Daily Treatment
7%
Diabetes
16%
Dietary Supplementation
9%
Divalent Metal Transporter 1 (DMT1)
8%
DNA Damage
16%
DNA Damage Response
6%
Doxycycline-inducible
7%
Dysregulation
10%
Dystrophy
36%
Endocannabinoid System
84%
Energy Balance
6%
Energy Homeostasis
13%
Energy Metabolism
15%
Energy Storage
7%
Energy Utilization
7%
ERK MAP Kinase
7%
Fat Mass
7%
Fatty Acids
9%
Feeding Behavior
7%
Flavopiridol
7%
Fold Increase
21%
G Protein-coupled Receptor 55
36%
General Control Nonderepressible 2 Kinase
14%
Generating Mechanism
6%
Glucose Tolerance
7%
Glycogen Synthase Kinase 3 (GSK3)
14%
Hyperactivity
7%
Impaired Insulin Secretion
43%
Inflammation
7%
Inhibitory Effect
7%
Insulin Action
22%
Insulin Resistance
55%
Insulin Sensitivity
30%
Insulin Sensitizers
7%
Insulin Signaling
11%
Integrated Stress Response
36%
Interleukin-6
7%
Inverse Agonist
7%
Iron Depletion
36%
L6 Myoblasts
5%
L6 Myotubes
7%
Lipid Intermediates
9%
Lipid Modulation
36%
Lipids
9%
Lipogenic Gene Expression
7%
Lipotoxicity
7%
Liver
19%
Low-grade Inflammation
7%
Mammalian Target of Rapamycin (mTOR)
49%
MEK-ERK
7%
Metabolic
43%
Metabolic Disorders
17%
Metabolic Dysfunction
40%
Metabolic Fuels
7%
Metabolic Function
13%
Metabolic Parameters
7%
Metabolic Tissues
36%
Mitochondrial Bioenergetics
7%
Mitochondrial Biology
7%
Mitochondrial Dynamics
7%
Mitochondrial Dysfunction
36%
Mitochondrial Fragmentation
7%
Mitochondrial Function
7%
Mitochondrial Homeostasis
9%
Mitochondrial Morphology
16%
Mitochondrial Respiration
5%
Mitochondrial Respiratory Function
16%
Mitofusin 2 (Mfn2)
16%
Mitogen-activated Protein Kinase
7%
Mitophagy
7%
MRNA Abundance
14%
MRNA Expression
7%
Multidrug-resistant
7%
Myoblast
5%
Myotubes
14%
NF-κB Pathway
7%
Nitrergic System
36%
Nuclear factor-κB
36%
Nutrient Surplus
7%
Obesity
28%
Off-target Effects
7%
Older Adults
14%
P38 MAP Kinase
7%
Palmitate
7%
Pancreatic Function
6%
Pathological Conditions
9%
PGC-1
10%
Pharmacological Inhibitors
7%
Pharmacological Intervention
9%
Phosphorylation
8%
Potential Contribution
6%
Protein Abundance
7%
Protein Complex
6%
Protein Drug
7%
Protein Phosphatase 2A (PP2A)
8%
Protein Synthesis
15%
Putative Drug Targets
10%
Reactive Oxygen Species
18%
Reactive Oxygen Species Signaling
6%
Receptor Blockade
7%
REDD+
36%
Redox Homeostasis
36%
Redox Modulation
6%
Redox Status
7%
Reduced Food Intake
7%
Regulatory System
7%
Repressor
7%
Rimonabant
29%
Roscovitine
7%
Scavenging Process
6%
Signaling System
21%
Skeletal muscle
93%
Skeletal muscle Cells
16%
Skeletal muscle Function
36%
Skeletal muscle Mass
36%
SLC38A2
36%
SNAT2
36%
Status Signaling
7%
System Function
10%
UCP3
14%
Medicine and Dentistry
Adipose Tissue
7%
Body Fat Mass
7%
C57BL/6
7%
Cannabinoid
36%
Cannabinoid 1 Receptor
36%
Cell Function
21%
Diabetes
21%
Diet Supplementation
9%
DNA Damage Response
36%
Endocannabinoid System
80%
Energy Balance
36%
Energy Metabolism
36%
Fatty Acid
9%
Food Intake
7%
Gene Expression
7%
Gene Repression
12%
Glucose Tolerance
7%
Homeostasis
96%
Hyperactivation
7%
Insulin Resistance
60%
Insulin Sensitivity
26%
Insulin Signaling
12%
Interleukin 6
12%
Inverse Agonist
7%
Lipotoxicity
12%
Malignant Neoplasm
9%
Messenger RNA
31%
Metabolic Disorder
48%
Mitochondrial Disorder
36%
Mitophagy
12%
Myotube
36%
Nitric Oxide
13%
Palmitic Acid
12%
Pancreatic Islet
36%
Protein Complex
36%
Reactive Oxygen Species
48%
Receptor
29%
Receptor Blocking
36%
Respiratory Physiology
12%
Rimonabant
29%
Sensitization
7%
Signal Transduction
9%
Skeletal Muscle
87%
Skeletal Muscle Cell
24%
Uncoupling Protein 3
24%
Biochemistry, Genetics and Molecular Biology
Activating Transcription Factor 4
14%
Adaptive Response
7%
Adipocyte
9%
Amino Acid Transporter
7%
Amino Acids
36%
ATF4
7%
Bioenergy
9%
Body Fat
9%
C57BL 6 Mouse
9%
Cannabinoid
13%
Cannabinoid Receptor Type 1
36%
Cell Function
25%
Cyclin-Dependent Kinase
14%
DNA Damage
18%
Dynamics
9%
Endocannabinoid System
86%
Energy Metabolism
9%
Fat Mass
9%
G Protein Coupled Receptor
36%
Gene Expression
9%
Gene Repression
9%
Genetics
9%
Homeostasis
59%
Insulin Resistance
59%
Insulin Sensitivity
36%
Insulin Signaling
45%
Interleukin 6
9%
Inverse Agonist
9%
Kinase
14%
Lipid
40%
Lipotoxicity
9%
Mammalian Target of Rapamycin Complex 1
36%
Messenger RNA
27%
MFN2
18%
Mitochondrial Disorder
36%
Mitogen-Activated Protein Kinase
7%
Mitophagy
9%
Nitric Oxide
13%
P38 Mitogen-Activated Protein Kinases
7%
Palmitic Acid
9%
Phosphatase
9%
Phosphotransferase
14%
Protein Biosynthesis
16%
Protein Kinase B
9%
Protein Phosphatase 2
9%
Receptor Blocking
36%
Repressor
7%
Respiratory Function
9%
Rimonabant
36%
SDHA
18%
Sensitization
9%
Signal Transduction
9%
Skeletal Muscle
100%
Transcription
7%
UCP3
18%
Upregulation
7%