0.5 billion events per second time correlated single photon counting using CMOS SPAD arrays

Nikola Krstajić, Simon Poland, James Levitt, Richard Walker, Ahmet T. Erdogan, Simon Ameer-Beg, Robert K Henderson

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    41 Citations (Scopus)
    189 Downloads (Pure)

    Abstract

    We present a digital architecture for fast acquisition of time correlated single photon counting (TCSPC) events from a 32×32 complementary metal oxide semiconductor (CMOS) single photon avalanche detector (SPAD) array (Megaframe) to the computer memory. Custom firmware was written to transmit event codes from 1024-TCSPC-enabled pixels for fast transfer of TCSPC events. Our 1024-channel TCSPC system is capable of acquiring up to 0.5×10(9) TCSPC events per second with 16 histogram bins spanning a 14 ns width. Other options include 320×10(6) TCSPC events per second with 256 histogram bins spanning either a 14 or 56 ns time window. We present a wide-field fluorescence microscopy setup demonstrating fast fluorescence lifetime data acquisition. To the best of our knowledge, this is the fastest direct TCSPC transfer from a single photon counting device to the computer to date.

    Original languageEnglish
    Pages (from-to)4305-8
    Number of pages4
    JournalOptics Letters
    Volume40
    Issue number18
    DOIs
    Publication statusPublished - 15 Sep 2015

    Keywords

    • CMOS
    • SPAD
    • Optical detectors
    • fluorescence lifetime
    • photon counting
    • Photons

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