2'-O-alkyloligoribonucleotides: Synthesis and applications in studying rna splicing

Brian S. Sproat, Adolfo Iribarren, Barbro Beijer, Uwe Pieles, Angus I. Lamond

    Research output: Contribution to journalArticlepeer-review

    31 Citations (Scopus)


    Improved synthetic routes have been established for the preparation of appropriately protected 2'-O-allylribonucleoside-3'-O-phosphoramidites. 2'-O-Allyloligoribonucleotides prove to be superior antisense compounds for investigating RNA processing.

    Original languageEnglish
    Pages (from-to)25-36
    Number of pages12
    JournalNucleosides and Nucleotides
    Issue number1-3
    Publication statusPublished - 1991

    ASJC Scopus subject areas

    • Biochemistry
    • Genetics


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