2'-O-alkyloligoribonucleotides: Synthesis and applications in studying rna splicing

Brian S. Sproat; Adolfo Iribarren; Barbro Beijer; Uwe Pieles; Angus I. Lamond

doi:10.1080/07328319108046433

2'-O-alkyloligoribonucleotides: Synthesis and applications in studying rna splicing

Brian S. Sproat, Adolfo Iribarren, Barbro Beijer, Uwe Pieles, Angus I. Lamond

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

Improved synthetic routes have been established for the preparation of appropriately protected 2'-O-allylribonucleoside-3'-O-phosphoramidites. 2'-O-Allyloligoribonucleotides prove to be superior antisense compounds for investigating RNA processing.

Original language	English
Pages (from-to)	25-36
Number of pages	12
Journal	Nucleosides and Nucleotides
Volume	10
Issue number	1-3
DOIs	https://doi.org/10.1080/07328319108046433
Publication status	Published - 1991

ASJC Scopus subject areas

Biochemistry
Genetics

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10.1080/07328319108046433

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title = "2'-O-alkyloligoribonucleotides: Synthesis and applications in studying rna splicing",

abstract = "Improved synthetic routes have been established for the preparation of appropriately protected 2'-O-allylribonucleoside-3'-O-phosphoramidites. 2'-O-Allyloligoribonucleotides prove to be superior antisense compounds for investigating RNA processing.",

author = "Sproat, {Brian S.} and Adolfo Iribarren and Barbro Beijer and Uwe Pieles and Lamond, {Angus I.}",

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T1 - 2'-O-alkyloligoribonucleotides

T2 - Synthesis and applications in studying rna splicing

AU - Sproat, Brian S.

AU - Iribarren, Adolfo

AU - Beijer, Barbro

AU - Pieles, Uwe

AU - Lamond, Angus I.

PY - 1991

Y1 - 1991

N2 - Improved synthetic routes have been established for the preparation of appropriately protected 2'-O-allylribonucleoside-3'-O-phosphoramidites. 2'-O-Allyloligoribonucleotides prove to be superior antisense compounds for investigating RNA processing.

AB - Improved synthetic routes have been established for the preparation of appropriately protected 2'-O-allylribonucleoside-3'-O-phosphoramidites. 2'-O-Allyloligoribonucleotides prove to be superior antisense compounds for investigating RNA processing.

UR - http://www.scopus.com/inward/record.url?scp=0026317833&partnerID=8YFLogxK

U2 - 10.1080/07328319108046433

DO - 10.1080/07328319108046433

M3 - Article

AN - SCOPUS:0026317833

SN - 0732-8311

VL - 10

SP - 25

EP - 36

JO - Nucleosides and Nucleotides

JF - Nucleosides and Nucleotides

IS - 1-3

ER -

2'-O-alkyloligoribonucleotides: Synthesis and applications in studying rna splicing

Abstract

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