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Why is quinidine an inhibitor of cytochrome P450 2D6? The role of key active-site residues in quinidine binding

McLaughlin, L. A., Paine, M. J. I., Kemp, C. A., Maréchal, J. D., Flanagan, J. U., Ward, C. J., Sutcliffe, M. J., Roberts, G. C. K. & Wolf, C. R., Sep 2005, In : Journal of Biological Chemistry. 280, 46, p. 38617-38624 8 p.

Research output: Contribution to journalArticle

Open Access
61 Citations (Scopus)
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Why 'knowledge transfer' is misconceived for applied social research

Davies, H., Nutley, S. & Walter, I., Jul 2008, In : Journal of Health Services Research and Policy. 13, 3, p. 188-190 3 p.

Research output: Contribution to journalArticle

146 Citations (Scopus)
19 Citations (Scopus)

Why older people do not participate in leisure time physical activity: a survey of activity levels, beliefs and deterrents

Crombie, I. K., Irvine, L., Williams, B., McGinnis, A. R., Slane, P. W., Alder, E. M. & McMurdo, M. E. T., May 2004, In : Age and Ageing. 33, 3, p. 287-292 6 p.

Research output: Contribution to journalArticle

232 Citations (Scopus)

Why students leave in the UK? an integrative review of the international research literature

Cameron, J., Roxburgh, M., Taylor, J. & Lauder, W., 2011, In : Journal of Clinical Nursing. 20, 7-8, p. 1086-1096 11 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Why the journey to mathematical excellence may be long in Scotland's primary schools

Henderson, S., 2012, In : Scottish Educational Review. 44, 1, p. 46-56 11 p.

Research output: Contribution to journalArticle

Open Access
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214 Downloads (Pure)

Why the Royal College of Surgeons should respect the wishes of “the Irish giant"

Muinzer, T. & Doyal, L., 2011, In : British Medical Journal. 343, p. 1290-1292 3 p.

Research output: Contribution to journalArticle

Why UK companies hedge interest rate risk

Dhanani, A., Fifield, S., Helliar, C. & Stevenson, L., 13 Mar 2007, In : Studies in Economics and Finance. 24, 1, p. 72-90 19 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access
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17 Citations (Scopus)
132 Downloads (Pure)

Widening access to UK medical education for under-represented socioeconomic groups: modelling the impact of the UKCAT in the 2009 cohort

Tiffin, P. A., Dowell, J. S. & McLachlan, J. C., 2012, In : BMJ. 344, p. - 27 p., e1805.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations

Chen, H., Common, J. E. A., Haines, R. L., Balakrishnan, A., Brown, S. J., Goh, C. S. M., Cordell, H. J., Sandilands, A., Campbell, L. E., Kroboth, K., Irvine, A. D., Goh, D. L. M., Tang, M. B. Y., van Bever, H. P., Giam, Y. C., McLean, W. H. I. & Lane, E. B., Jul 2011, In : British Journal of Dermatology. 165, 1, p. 106-114 9 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Widespread arginine phosphorylation in human cells–a novel protein PTM revealed by mass spectrometry

Fu, S., Fu, C., Zhou, Q., Lin, R., Ouyang, H., Wang, M., Sun, Y., Liu, Y. & Zhao, Y., 1 Mar 2020, In : Science China Chemistry. 63, 3, p. 341-346 6 p.

Research output: Contribution to journalArticle

Widespread sulfenic acid formation in tissues in response to hydrogen peroxide

Saurin, A. T., Neubert, H., Brennan, J. P. & Eaton, P., 28 Dec 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 52, p. 17982-17987 6 p.

Research output: Contribution to journalArticle

225 Citations (Scopus)

Wide variation in surgical outcomes for acromegaly in the UK

Bates, P. R., Carson, M. N., Trainer, P. J., Wass, J. A. H., Bevan, J. S., Atkinson, A. B., Peacey, S. R., Stewart, P. M., Sheppard, M. C., Dayan, C. M., Chatterjee, K., Scanlon, M. F., Leese, G. P., Walker, B. R., Patrick, A. W., Vaidya, B., Connell, J. M. C., Allan, B., Atkin, S. L., Orme, S. & 61 others, Howlett, T. A., Vora, J. P., Jenkins, P. J., Aylwin, S., Bouloux, P., Davis, J. R. E., Shalet, S., James, R. A., Howell, S. J., Vice, P. A., Newell-Price, J., Ross, R. J. M., Clayton, R. N., Jennings, P., Booth, A., Alexander, A., Holden, N., Jablonski, L., Wright, D., Hunt, M., Taheri, J., Holmes, C., Woods, E., Brown, T., Roberts, S., Carson, M., Goss, L., Revesz, S., Campbell, K., Grant, D., Smith, C., Cleary, S., Spink, C., Howlett, T., Chapman, M., Corlett, P., Morton, B., Whittingham, P., Conrich, L., Gaygon, C., Owusu-Antwi, S., Stobie, E., Walker-Scott, E., Gilbert, J., Drowley, T., Gibson, C., Roberts, M., Gebbie, J., Henderson, P., Johnstone, K., Murphy, A., Cowshill, C., Fazal-Sanderson, V., Smith, R., Parkington, S., Doane, A., Ibbotson, V., Lynch, R., Brown, M., Barry, E. & Brown, N., 2008, In : Clinical Endocrinology. 68, 1, p. 136-142 7 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)

Wildlife Penalties Review: Note on report by Prof. Poustie for Scottish Government on Penalties for Wildlife Crime

Reid, C., Apr 2016, Scottish Planning and Environmental Law, 174, p. 28 1 p.

Research output: Contribution to specialist publicationArticle

Wildlife reforms in Scotland

Reid, C. T., 2010, In : Environmental Law Review. 12, 4, p. 256-265 10 p.

Research output: Contribution to journalArticle

Wild-type p53 activates SAP expression in lymphoid cells

Nagy, N., Takahara, M., Nishikawa, J., Bourdon, J. C., Kis, L. L., Klein, G. & Klein, E., 2004, In : Oncogene. 23, 53, p. 8563-8570 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Will attracting the "creative class" boost economic growth in old industrial regions? A case study of Scotland

Houston, D., Findlay, A., Harrison, R. & Mason, C., 2008, In : Geografiska Annaler: Series B, Human Geography. 90, 2, p. 133-149 17 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Willed Forgetfulness: The Arts, Education and the Case for Unlearning

Baldacchino, J., Jul 2013, In : Studies in Philosophy and Education. 32, 4, p. 415-430 16 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Willingness to pay for climate change mitigation: evidence from China

Li, Y., Mu, X., Schiller, A. & Zheng, B., 31 Jan 2016, In : Energy Journal. 37, China Special Issue, p. 179-194 16 p.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
169 Downloads (Pure)

Willingness to pay to reduce alcohol-related harm in Australian rural communities

Petrie, D., Doran, C. & Shakeshaft, A., Jun 2011, In : Expert Review of Pharmacoeconomics & Outcomes Research. 11, 3, p. 351-363 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Will MRI screening deliver the expected survival advantage in BRCA 1 carriers?

Hamilton, L. J., Evans, A. J., Cornford, E. J., Rakha, E. A., Ellis, I. O. & Foulkes, W. D., 1 Nov 2009, In : Clinical Radiology. 64, 11, p. 1045-1047 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Will rising atmospheric CO2 concentration inhibit nitrate assimilation in shoots but enhance it in roots of C3 plants?

Andrews, M., Condron, L. M., Kemp, P. D., Topping, J. F., Lindsey, K., Hodge, S. & Raven, J. A., 20 Mar 2020, In : Physiologia Plantarum. 12 p.

Research output: Contribution to journalArticle

Will the Ubiquitin System Furnish as Many Drug Targets as Protein Kinases?

Cohen, P. & Tcherpakov, M., 24 Nov 2010, In : Cell. 143, 5, p. 686-693 8 p.

Research output: Contribution to journalArticle

201 Citations (Scopus)

Wireless machine-to-machine networks

He, J., Zhang, Y., Fan, Z., Chen, H-H. & Bai, L., 13 Dec 2012, In : International Journal of Distributed Sensor Networks. 8, 12, 2 p.

Research output: Contribution to journalArticle

Open Access
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58 Downloads (Pure)

Wireless mobile technology to improve workflow and feasibility of MR-guided percutaneous interventions

Rube, M. A., Holbrook, A. B., Cox, B. F., Buciuc, R. & Melzer, A., 1 May 2015, In : International Journal of Computer Assisted Radiology and Surgery. 10, 5, p. 665-676 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Wireless MR tracking of interventional devices using phase-field dithering and projection reconstruction

Rube, M. A., Holbrook, A. B., Cox, B. F., Houston, J. G. & Melzer, A., Jul 2014, In : Magnetic Resonance Imaging. 32, 6, p. 693-701 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

WISECARE+: Results of a European study of a nursing intervention for the management of chemotherapy-related symptoms

Kearney, N., Miller, M., Maguire, R., Dolan, S., MacDonald, R., McLeod, J., Maher, L., Sinclair, L., Norrie, J. & Wengstrom, Y., 2008, In : European Journal of Oncology Nursing. 12, 5, p. 443-448 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Withdrawal of inhaled corticosteroids in COPD: A European Respiratory Society Guideline

Chalmers, J. D., Laska, I. F., Franssen, F. M. E., Janssens, W., Pavord, I., Rigau, D., McDonnell, M. J., Roche, N., Sin, D. D., Stolz, D., Suissa, S., Wedzicha, J. & Miravitlles, M., 1 Jun 2020, In : European Respiratory Journal. 55, 6, p. 1-12 12 p., 2000351.

Research output: Contribution to journalArticle

Within-patient right-left blinded comparison of diode (810 nm) laser therapy and intense pulsed light therapy for hair removal

Cameron, H., Ibbotson, S. H., Dawe, R. S., Ferguson, J. & Moseley, H., Oct 2008, In : Lasers in Medical Science. 23, 4, p. 393-397 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Within-Word Inspection Strategies in Continuous Reading: Time Course of Perceptual, Lexical, and Contextual Processes

Pynte, J., Kennedy, A. & Murray, W. S., 1 May 1991, In : Journal of Experimental Psychology: Human Perception and Performance. 17, 2, p. 458-470 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Witness intimidation, forced migration and resettlement: a British case study

Fyfe, N. R. & McKay, H., Apr 2000, In : Transactions of the Institute of British Geographers. 25, 1, p. 77-90 14 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
6 Citations (Scopus)

Witness protection: The UK experience in comparative context

Fyfe, N., 2007, In : Covert Policing Review. 1, p. 12-18 7 p.

Research output: Contribution to journalArticle

Wittgenstein's Tractatus Project as Philosophy of Information

Young, R., 2004, In : Minds and Machines. 14, 1, p. 119-132 14 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate

Vitari, A. C., Deak, M., Collins, B. J., Morrice, N., Prescott, A. R., Phelan, A., Humphreys, S. & Alessi, D. R., 15 Feb 2004, In : Biochemical Journal. 378, 1, p. 257-268 12 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons

Friedel, P., Kahle, K. T., Zhang, J., Hertz, N., Pisella, L. I., Buhler, E., Schaller, F., Duan, J., Khanna, A. R., Bishop, P. N., Shokat, K. M. & Medina, I., 30 Jun 2015, In : Science Signaling. 8, 383, 16 p., ra65.

Research output: Contribution to journalArticle

42 Citations (Scopus)

WNK3-SPAK Interaction is Required for the Modulation of NCC and other Members of the SLC12 Family

Pacheco-Alvarez, D., Vazquez, N., Castaneda-Bueno, M., De-Los-Heros, P., Cortes-Gonzalez, C., Moreno, E., Meade, P., Bobadilla, N. A. & Gamba, G., 2012, In : Cellular Physiology and Biochemistry. 29, 1-2, p. 291-302 12 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner

Brown, K., Yang, P., Nobre Salvador, D., Kulikauskas, R., Ruohola-Baker, H., Robitaille, A. M., Chien, A. J., Moon, R. T. & Sherwood, V., 1 Jun 2017, In : Oncogene. 36, 22, p. 3119-3136 18 p.

Research output: Contribution to journalArticle

Open Access
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24 Citations (Scopus)
219 Downloads (Pure)

Wnt3a-mediated chemorepulsion controls movement patterns of cardiac progenitors and requires RhoA function

Yue, Q., Wagstaff, L., Yang, X., Weijer, C. & Munsterberg, A., 15 Mar 2008, In : Development. 135, 6, p. 1029-1037 9 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Wnt5a Exhibits Layer-Specific Expression in Adult Skin, Is Upregulated in Psoriasis, and Synergizes with Type 1 Interferon

Romanowska, M., Evans, A., Kellock, D., Bray, S. E., McLean, K., Donandt, S. & Foerster, J., 28 Apr 2009, In : PLoS ONE. 4, 4, p. - 10 p., e5354.

Research output: Contribution to journalArticle

43 Citations (Scopus)
12 Citations (Scopus)

Wnt5a inhibits the CpG oligodeoxynucleotide-triggered activation of human plasmacytoid dendritic cells

Hack, K., Reilly, L., Proby, C., Fleming, C., Leigh, I. & Foerster, J., Apr 2012, In : British Journal of Dermatology. 166, 4, p. e36-e36 1 p., P-24.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Wnt5a is strongly expressed at the leading edge in non-melanoma skin cancer, forming active gradients, while canonical wnt signalling is repressed

Pourreyron, C., Reilly, L., Proby, C., Panteleyev, A., Fleming, C., McLean, K., South, A. P. & Foerster, J., 22 Feb 2012, In : PLoS ONE. 7, 2

Research output: Contribution to journalArticle

42 Citations (Scopus)

WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism

Sherwood, V., Chaurasiya, S. K., Ekström, E. J., Guilmain, W., Liu, Q., Koeck, T., Brown, K., Hansson, K., Agnarsdóttir, M., Bergqvist, M., Jirström, K., Ponten, F., James, P. & Andersson, T., Apr 2014, In : Carcinogenesis. 35, 4, p. 784-794 11 p.

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)

Wnt regulates amino-acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos

Poncet, N., Halley, P., Lipina, C., Gierlinski, M., Dady, A., Singer, G., Febrer, M., Shi, Y-B., Yamaguchi, T. P., Taylor, P. & Storey, K., 7 Jan 2020, In : EMBO Reports. 21, 1, p. 1-20 20 p., e48469.

Research output: Contribution to journalArticle

Open Access
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57 Downloads (Pure)

WNT signaling: an emerging mediator of cancer cell metabolism?

Sherwood, V., Jan 2015, In : Molecular and Cellular Biology. 35, 1, p. 2-10 9 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

Wnt signals provide a timing mechanism for the FGF-retinoid differentiation switch during vertebrate body axis extension

Olivera-Martinez, I. & Storey, K. G., Jun 2007, In : Development. 134, 11, p. 2125-2135 11 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

Wolbachia infection suppresses both host defence and parasitoid counter-defence

Fytrou, A., Schofield, P. G., Kraaijeveld, A. R. & Hubbard, S. F., Apr 2006, In : Proceedings of the Royal Society B. 273, 1588, p. 791-796 6 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)