Find Research Outputs

2018

Amine Containing Analogs of Sulindac for Cancer Prevention

Mathew, B., Hobrath, J. V., Connelly, M. C., Guy, R. K. & Reynolds, R. C., 31 Jan 2018, In : Open Medicinal Chemistry Journal. 12, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
File
Sulindac
Amines
Libraries
Neoplasms
Adenomatous Polyps
1 Citations

A minimally invasive tool to study immune response and skin barrier in children with atopic dermatitis

Hulshof, L., Hack, D. P., Hasnoe, Q. C. J., Dontje, B., Jakasa, I., Riethmüller, C., McLean, W. H. I., van Aalderen, W. M. C., Van't Land, B., Kezic, S., Sprikkelman, A. B. & Middelkamp-Hup, M. A., 10 Jul 2018, In : British Journal of Dermatology. 10 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Skin
Biomarkers
Interleukins
Chemokine CCL8

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

Loftus, R. M., Assmann, N., Kedia-Mehta, N., O'Brien, K. L., Garcia, A., Gillespie, C., Hukelmann, J. L., Oefner, P. J., Lamond, A. I., Gardiner, C. M., Dettmer, K., Cantrell, D. A., Sinclair, L. V. & Finlay, D. K., 14 Jun 2018, In : Nature Communications. 9, 1, p. 1-15 15 p., 2341.

Research output: Contribution to journalArticle

Open Access
File
Natural Killer Cells
mice
amino acids
Lymphocytes
Glutamine
2 Citations

A Missense Mutation within the Helix Termination Motif of KRT25 Causes Autosomal Dominant Woolly Hair/Hypotrichosis

Yu, X., Chen, F., Ni, C., Zhang, G., Zheng, L., Zhang, J., Li, C., Sandilands, A., Yao, Z. & Li, M., Jan 2018, In : Journal of Investigative Dermatology. 138, 1, p. 230-233 4 p.

Research output: Contribution to journalLetter

Open Access
File
Open Access
File
Dental General Practices
Feasibility Studies
Tooth
Communication
Health

A modified CPT based installation torque prediction for large screw piles in sand

Davidson, C., Al-Baghdadi, T., Brown, M., Brennan, A., Knappett, J., Augarde, C., Coombs, W., Wang, L., Richardson, D., Blake, A. & Ball, J., 13 Jun 2018, Cone Penetration Testing 2018: Proceedings of the 4th International Symposium on Cone Penetration Testing. Hicks, M. A., Pisanò, F. & Peuchen, J. (eds.). 1 ed. CRC Press, p. 255-261 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
Piles
Cones
Sand
Torque
Centrifuges
1 Citations

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors

Harrison, J. R., Brand, S., Smith, V., Robinson, D. A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L. S., Collie, I., Hallyburton, I., Norval, S., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Brenk, R., Wyatt, P. G., Gilbert, I. H. & Read, K. D., 12 Sep 2018, In : Journal of Medicinal Chemistry. 61, 18, p. 8374–8389 16 p.

Research output: Contribution to journalArticle

Open Access
File
African Trypanosomiasis
Trypanosoma brucei brucei
Crystallography
Central Nervous System Diseases
Peripheral Nervous System
Open Access
File
Ions
DNA
Enzymes
Substrate Specificity
Catalytic Domain
39 Citations

AMPK: Sensing Glucose as well as Cellular Energy Status

Lin, S-C. & Hardie, D., 6 Feb 2018, In : Cell Metabolism. 27, 2, p. 299-313 15 p.

Research output: Contribution to journalReview article

Open Access
File
AMP-Activated Protein Kinases
Glucose
Adenosine Triphosphatases
Fructose-Bisphosphate Aldolase
Adenosine Triphosphate

Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study

Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In : Diabetologia. 61, 12, p. 2590-2597 8 p.

Research output: Contribution to journalArticle

Open Access
File
Amputation
Ulcer
Observational Studies
Foot
Scotland

A Multicellular Model of Intestinal Crypt Buckling and Fission

Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In : Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.

Research output: Contribution to journalArticle

Open Access
File
intestinal crypts
buckling
Buckling
Organoids
Tissue
2 Citations

A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase

Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.

Research output: Contribution to journalArticle

Open Access
File
shikimate kinase
Enzyme inhibition
Mycobacterium tuberculosis
Assays
Screening

An acute transfusion reaction

Webb, C., Norris, A. & Hands, K., 1 Feb 2018, In : Clinical Medicine - Journal of the Royal College of Physicians of London. 18, 1, p. 95-97 3 p.

Research output: Contribution to journalArticle

Anti-Idiotypic Antibodies
Blood Component Transfusion
IgA Deficiency
Anaphylaxis
Incidence

Análisis de la formación y el ámbito de práctica de los médicos de atención primaria en Inglaterra, Alemania y España

Glonti, K., Struckmann, V., Alconada, A., Pettigrew, L. M., Hernandez-Santiago, V., Minue, S., Risso-Gill, I., McKee, M. & Legido-Quigley, H., 22 Mar 2018, In : Gaceta Sanitaria. 8 p.

Research output: Contribution to journalArticle

Open Access
File
England
Spain
Germany
Primary Health Care
General Practitioners
Open Access
Soils
Reinforcement
Rubber
Sand
soil

Analysis of novel missense ATR mutations reveals new splicing defects underlying Seckel Syndrome

Llorens-Agost, M., Luessing, J., van Beneden, A., Eykelenboom, J., O'Reilly, D., Bicknell, L. S., Reynolds, J. J., van Koegelenberg, M., Hurles, M. E., Brady, A. F., Jackson, A. P., Stewart, G. S. & Lowndes, N. F., 17 Nov 2018, In : Human Mutation. 39, 12, p. 1847-1853 7 p.

Research output: Contribution to journalArticle

Ataxia Telangiectasia
Missense Mutation
Mutation
Microcephaly
Inborn Genetic Diseases
30 Citations

Analysis of shared heritability in common disorders of the brain

Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 30 othersLetenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J-F., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Farrer, L. A., Barnes, L. L., Beach, T. G., Demirci, F. Y., Head, E., Hulette, C. M., Jicha, G. A., Kauwe, J. S. K., Kaye, J. A., Smith, A. G., Matthews, K., McIntosh, A., Robertson, M. M. & Cohen, D., 22 Jun 2018, In : Science. 360, 6395, p. 1-15 15 p., eaap8757.

Research output: Contribution to journalArticle

Open Access
File
Brain Diseases
Psychiatry
Phenotype
Genetic Heterogeneity
Genome-Wide Association Study

An Anti-Pattern for Misuse Cases

Dashti, M. T. & Radomirović, S., 2018, Computer Security - ESORICS 2017 International Workshops, CyberICPS 2017 and SECPRE 2017, Revised Selected Papers: ESORICS 2017 International Workshops, CyberICPS 2017 and SECPRE 2017, Oslo, Norway, September 14-15, 2017, Revised Selected Papers. Katsikas, S. K., Cuppens, F., Cuppens, N., Lambrinodakis, C., Kalloniatis, C., Mylopoulos, J., Anton, A. & Gritzalis, S. (eds.). Switzerland: Springer , Vol. 10683. p. 250-261 12 p. (Lecture Notes in Computer Science; vol. 10683).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
Requirements engineering
Communication
Genetic Counseling
High-Throughput Nucleotide Sequencing
Neoplasms
Hope
Exome

Anatomía e importancia clínica del clivus extracraneal y las estructuras circundantes

Erdem, H., Kizilkanat, E. D., Boyan, N., Soames, R. & Oguz, O., 1 Jun 2018, In : International Journal of Morphology. 36, 2, p. 557-562 6 p.

Research output: Contribution to journalArticle

Open Access
File
Foramen Magnum
Posterior Cranial Fossa
Anatomy
Bone and Bones
Foramen Ovale

Anatomy of the glenohumeral ligaments

Alashkham, A., Alraddadi, A. & Soames, R., 2018, In : Italian Journal of Anatomy and Embryology. 123, 2, p. 114-126 13 p.

Research output: Contribution to journalArticle

Open Access
File
Ligaments
Anatomy
Shoulder Joint
Humerus
Social Sciences

An audit of Ninewells Hospital fertility preservation service

Chatterton, F. & Kay, V., 26 Jun 2018, In : Journal of Obstetrics & Gynaecology. 38, 5, p. 732 1 p.

Research output: Contribution to journalArticle

Fertility Preservation
Spermatozoa
Fertility
Testicular Neoplasms
Hematologic Neoplasms
Orthodontics
Meta-Analysis
Randomized Controlled Trials
Tooth
Databases
Open Access
File
liquefied natural gas
natural gas
economics
electricity generation
profitability
6 Citations

An evidence-based treatment algorithm for colorectal polyp cancers: results from the Scottish Screen-detected Polyp Cancer Study (SSPoCS)

Richards, C. H., Ventham, N. T., Mansouri, D., Wilson, M., Ramsay, G., Mackay, C. D., Parnaby, C. N., Smith, D., On, J., Speake, D., McFarlane, G., Neo, Y. N., Aitken, E., Forrest, C., Knight, K., McKay, A., Nair, H., Mulholland, C., Robertson, J. H., Carey, F. A. & 2 othersSteele, R. J. C. & on behalf of the Scottish Surgical Research Group, Feb 2018, In : Gut. 67, 2, p. 299-306 8 p.

Research output: Contribution to journalArticle

Open Access
File
Polyps
Colorectal Neoplasms
Neoplasms
Residual Neoplasm
Therapeutics
1 Citations

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis

Liakath-Ali, K., Mills, E. W., Sequeira, I., Lichtenberger, B. M., Pisco, A. O., Sipilä, K. H., Mishra, A., Yoshikawa, H., Wu, C. C-C., Ly, T., Lamond, A. I., Adham, I. M., Green, R. & Watt, F. M., 11 Apr 2018, In : Nature. 556, p. 376-380 5 p.

Research output: Contribution to journalLetter

Open Access
File
Ribosomes
Homeostasis
Stem Cells
Sirolimus
Quality Control

A new approach for determination of free carriers lifetime and density of localised states in disordered semiconductors

Belgacem, H. & Reynolds, S., 15 Oct 2018, In : Philosophical Magazine. 99, 2, p. 131-147 17 p.

Research output: Contribution to journalArticle

Carrier lifetime
Photoconductivity
Carrier concentration
Semiconductor materials
Laplace transforms
1 Citations

A new complementary approach for oral health and diabetes management: health coaching

Cinar, A. B., Freeman, R. & Schou, L., 24 Jan 2018, In : International Dental Journal. 68, 1, p. 54-64 11 p.

Research output: Contribution to journalArticle

Open Access
File
Oral Health
Health
Health Education
Type 2 Diabetes Mellitus
Denmark

A new Editor-in-Chief for Development

Bray, S., Storey, K. & Brown, K., 27 Mar 2018, In : Development. 145, 6, 2 p., dev165266.

Research output: Contribution to journalEditorial

A New Measure of Hallucinatory States and a Discussion of REM Sleep Dreaming as a Virtual Laboratory for the Rehearsal of Embodied Cognition

Speth, C. & Speth, J., 25 Jan 2018, In : Cognitive Science. 42, 1, p. 311-333 23 p.

Research output: Contribution to journalArticle

REM Sleep
Cognition
Sleep
Imagery (Psychotherapy)
Executive Function

A new model of undergraduate clinical education?

Bartlett, M. & Muir, F., 26 Apr 2018, In : British Journal of General Practice. 68, 670, p. 216-217 2 p.

Research output: Contribution to journalEditorial

An Expanded Mixed Finite Element Method for Two-dimensional Sobolev Equations

Li, N., Lin, P. & Gao, F., 7 Sep 2018, In : Journal of Computational and Applied Mathematics. 348, p. 342-355 14 p.

Research output: Contribution to journalArticle

Mixed Finite Element Method
Finite element method
Optimal Error Estimates
Verify
Numerical Examples

Animating Archaeopteryx

Body, B., 15 Feb 2018.

Research output: Contribution to conferencePaper

1 Citations

An innovative long final year assistantship in general practice: description and evaluation

McKinley, RK., Bartlett, M., Gay, SP., Gibson, S., Panesar, A. & Webb, M., 2 Jan 2018, In : Education for Primary Care. 29, 1, p. 35-42 8 p.

Research output: Contribution to journalArticle

General Practice
Students
Medical Students
Learning
Education

An Integrated Approach Providing Scientific and Policy-Relevant Insights for South-West Bangladesh

Nicholls, R. J., Hutton, C. W., Lazar, A. N., Adger, W. N., Allan, A., Whitehead, P. G., Wolf, J., Rahman, M., Salehin, M., Hanson, S. E. & Payo, A., May 2018, Ecosystem Services for Well-Being in Deltas: Integrated Assessment for Policy Analysis. Nicholls, R. J., Hutton, C. W., Adger, W. N., Hanson, S. E., Rahman, M. M. & Salehin, M. (eds.). Palgrave Macmillan, p. 49-69 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Open Access
File
integrated approach
climate change
ecosystem service
poverty
economic development
2 Citations

An interface approach based on moving mesh and cohesive modeling in Z-pinned composite laminates

Funari, M. F., Greco, F., Lonetti, P., Luciano, R. & Penna, R., 15 Feb 2018, In : Composites Part B: Engineering. 135, p. 207-217 11 p.

Research output: Contribution to journalArticle

Debonding
Laminates
Composite materials
Coalescence
Crack initiation

An international study of the quality of life of adult patients treated with home parenteral nutrition

Baxter, J. P., Fayers, P. M., Bozzetti, F., Kelly, D., Joly, F., Wanten, G., Jonkers, C., Cuerda, C., van Gossum, A., Klek, S., Boudreault, M-F., Gilbert, A., Jobin, M., Staun, M., Gillanders, L., Forbes, A., O'Callaghan, M., Faedo, C. M., Brunelli, C., Mariani, L. & 1 othersPironi, L., 6 Aug 2018, In : Clinical Nutrition. 9 p.

Research output: Contribution to journalArticle

Home Parenteral Nutrition
Quality of Life
Psychometrics
Linear Models
Crohn Disease

An Interview with Catherine Malabou: Toward epigenetic philosophy

Malabou, C., Ruda, F. & Hamza, A., 15 Mar 2018, 13 p.

Research output: Other contribution

An introduction to bird flight

Body, B., 16 Feb 2018.

Research output: Contribution to conferencePaper

flight
bird
1 Citations

An Investigation of the Weak Form of the Efficient Markets Hypothesis for the Kuwait Stock Exchange

Almujamed, H. I., Fifield, S. G. M. & Power, D. M., Apr 2018, In : Journal of Emerging Market Finance. 17, 1, p. 1-28 28 p.

Research output: Contribution to journalArticle

Open Access
File
Efficient market hypothesis
Kuwait
Stock exchange
Trading rules
Price changes
2 Citations

An isotope dilution based-targeted and non-targeted carbonyl neurosteroid/steroid profiling

Sharp, S., Mitchell, S., Vallée, M., Kuzmanova, E., Cooper, M., Belelli, D., Lambert, J. & Huang, J., 17 Apr 2018, In : Analytical Chemistry. 90, 8, p. 5247-5255 9 p.

Research output: Contribution to journalArticle

Isotopes
Dilution
Neurotransmitter Agents
Steroids
Brain

An NMRA-like protein regulates gene expression in Phytophthora capsici to drive the infection cycle on tomato

Pham, J., Stam, R., Heredia, V. M., Csukai, M. & Huitema, E., Jun 2018, In : Molecular Plant - Microbe Interactions. 31, 6, p. 665-677 13 p.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora
Phytophthora capsici
Lycopersicon esculentum
tomatoes
Gene Expression

An occupational therapy perspective on cognitive stimulation therapy: targeting occupational performance and outcomes for people with dementia.

Rehling, T., Pilkington, A., Sixsmith, J., Corr, S. & Chard, G., 25 May 2018.

Research output: Contribution to conferencePaper

Occupational Therapy
Cognitive Therapy
Dementia
Activities of Daily Living
Aptitude

A novel light source with tuneable uniformity of light distribution for artificial daylight photodynamic therapy

O'Mahoney, P., Haigh, N., Wood, K., Brown, C. T. A., Ibbotson, S. & Eadie, E., Sep 2018, In : Photodiagnosis and photodynamic therapy. 23, p. 144-150 7 p.

Research output: Contribution to journalArticle

Photochemotherapy
Light
Weather
Leg
Therapeutics
Femur
Magnetic Resonance Spectroscopy
Growth Plate
Epiphyses
Hospital Radiology Department

An overview of realist evaluation for simulation-based education

Graham, A. C. & McAleer, S., 17 Jul 2018, In : Advances in Simulation. 3, p. 1-8 8 p., 13.

Research output: Contribution to journalArticle

Open Access
File
Education
Medical Students
Research
Research Personnel
2 Citations

Antibiotics and antibiotic resistance genes in global lakes: A review and meta-analysis

Yang, Y., Song, W., Lin, H., Wang, W., Du, L. & Xing, W., Jul 2018, In : Environment International. 116, p. 60-73 14 p.

Research output: Contribution to journalReview article

antibiotic resistance
meta-analysis
antibiotics
gene
lake
2 Citations

Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity

Lum, F-M., Couderc, T., Chia, B-S., Ong, R-Y., Her, Z., Chow, A., Leo, Y-S., Kam, Y-W., Rénia, L., Lecuit, M. & Ng, L. F. P., 30 Jan 2018, In : Scientific Reports. 8, 1, p. 1-14 14 p., 1860.

Research output: Contribution to journalArticle

Open Access
File
Chikungunya virus
Virus Diseases
Antibodies
Viral RNA
Viral Load
3 Citations
Open Access
File
Attention Deficit Disorder with Hyperactivity
Antidepressive Agents
Observational Studies
Confidence Intervals
Pregnancy