Find Research Outputs

2018

A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism

Roberts, A., Dunne, J., Scullion, S., Norval, S. & Fairlamb, A., 29 Aug 2018, In : Biochemical Journal. 475, 16, p. 2593-2610 18 p.

Research output: Contribution to journalArticle

Open Access
File
Pyruvaldehyde
Isoprostanes
Glyoxal
Metabolism
Prostaglandins
3 Citations

Array-based sequencing of filaggrin gene for comprehensive detection of disease-associated variants

Wong, X. F. C. C., Denil, S. L. I. J., Foo, J. N., Chen, H., Ling Tay, A. S., Haines, R. L., Tang, M. B. Y., McLean, W. H. I., Sandilands, A., Smith, F. J. D., Lane, E. B., Liu, J. & Common, J. E. A., Feb 2018, In : Journal of Allergy and Clinical Immunology. 141, 2, p. 814-816 3 p.

Research output: Contribution to journalLetter

Open Access
File
Atopic Dermatitis
Genes
Costs and Cost Analysis
Polymerase Chain Reaction
filaggrin

A Scoping Review Exploration of the Intended and Unintended Consequences of eHealth on Older People: A Health Equity Impact Assessment

Fang, M. L., Siden, E., Korol, A., Demestihas, M-A., Sixsmith, J. & Sixsmith, A., Nov 2018, In : Human Technology. 14, 3, p. 297-323 27 p.

Research output: Contribution to journalArticle

Open Access
File
Health Impact Assessment
Telemedicine
equity
Health
Economics

A SHERPA approach to surgical training in parotidectomy

Gutai, F., Chai, C. S., Hogg, G., Mountain, R. & Fioratou, E., Jul 2018, In : International Journal of Surgery . 55, Supplement 1, p. S102 1 p., 0505.

Research output: Contribution to journalArticle

Consultants
Focus Groups
Facial Nerve
Statistical Factor Analysis
Learning

A simple approach to confine leeches to a digital flap

Ho, P. H., Khan, M. A. A. & Hogg, F. J., 1 Mar 2018, In : JPRAS Open. 15, p. 1-3 3 p.

Research output: Contribution to journalLetter

Open Access
File
1 Citations

Asking different questions: A call to action for research to improve the quality of care for every woman, every child

Kennedy, H. P., Cheyney, M., Dahlen, H. G., Downe, S., Foureur, M. J., Homer, C. S. E., Jefford, E., McFadden, A., Michel-Schuldt, M., Sandall, J., Soltani, H., Speciale, A. M., Stevens, J., Vedam, S. & Renfrew, M. J., 1 Aug 2018, In : Women and Birth. 31, 4, p. 242-243 2 p.

Research output: Contribution to journalArticle

Asking different questions: A call to action for research to improve the quality of care for every woman, every child

Kennedy, H. P., Cheyney, M., Dahlen, H. G., Downe, S., Foureur, M. J., Homer, C. S. E., Jefford, E., McFadden, A., Michel-Schuldt, M., Sandall, J., Soltani, H., Speciale, A. M., Stevens, J., Vedam, S. & Renfrew, M. J., Oct 2018, In : Midwifery. 65, p. 16-17 2 p.

Research output: Contribution to journalComment/debate

3 Citations

Asking different questions: A call to action for research to improve the quality of care for every woman, every child

Kennedy, H. P., Cheyney, M., Dahlen, H. G., Downe, S., Foureur, M. J., Homer, C. S. E., Jefford, E., McFadden, A., Michel-Schuldt, M., Sandall, J., Soltani, H., Speciale, A. M., Stevens, J., Vedam, S. & Renfrew, M. J., Sep 2018, In : Birth. 45, 3, p. 222-231 10 p.

Research output: Contribution to journalComment/debate

Quality of Health Care
Health Services Research
Research
Economics
Postnatal Care

Asking Different Questions: A Call to Action for Research to Improve the Quality of Care for Every Woman, Every Child

Kennedy, H. P., Cheyney, M., Dahlen, H. G., Downe, S., Foureur, M. J., Homer, C. S. E., Jefford, E., McFadden, A., Michel-Schuldt, M., Sandall, J., Soltani, H., Speciale, A. M., Stevens, J., Vedam, S. & Renfrew, M. J., Sep 2018, In : Journal of Midwifery and Women's Health. 63, 5, p. 516-517 2 p.

Research output: Contribution to journalComment/debate

Quality of Health Care
Health Services Research
Parturition

Asparaginyl endopeptidase (Legumain) supports human Th1 induction via cathepsin L-mediated intracellular C3 activation

Freeley, S., Cardone, J., Günther, S. C., West, E. E., Reinheckel, T., Watts, C., Kemper, C. & Kolev, M. V., 24 Oct 2018, In : Frontiers in Immunology. 9, p. 1-7 7 p., 2449.

Research output: Contribution to journalArticle

Open Access
File
asparaginylendopeptidase
Cathepsin L
T-Lymphocytes
Thymosin
Complement Receptors

Assessing ADHD symptoms in children and adults: Evaluating the role of objective measures

Emser, T. S., Johnston, B., Steele, J., Kooij, S., Thorell, L. & Christiansen, H., 18 May 2018, In : Behavioral and Brain Functions. 14, p. 1-14 14 p., 11.

Research output: Contribution to journalArticle

Open Access
File
Guidelines
Interviews
Support Vector Machine
1 Citations
Open Access
File
Climate Change
climate change
Climate change
risk assessment
ecosystems

Assessing the effectiveness of NICE criteria for stratifying breast cancer risk in a UK cohort

Littlejohn, L. A., Gibbs, J., Jordan, L. B., Miedzybrodzka, Z. H., Bell, C., Goudie, D., Dunlop, J. & Berg, J. N., 15 Jan 2018, In : European Journal of Human Genetics. 26, 4, p. 599-603 5 p.

Research output: Contribution to journalArticle

Open Access
File
National Institutes of Health (U.S.)
Breast Neoplasms
Delivery of Health Care
Genetic Services
Guidelines
Open Access
File
Inappropriate Prescribing
Chronic Obstructive Pulmonary Disease
Observational Studies
Adrenal Cortex Hormones
Delivery of Health Care

Assessment of anxiety

Freeman, R. & Humphris, G., 8 Jun 2018, In : British Dental Journal. 224, 11, p. 843-844 2 p.

Research output: Contribution to journalLetter

Assessment of biophysical properties of Royal Belum tropical forest, Malaysia

Kanniah, K. D., Tan, K. P., Cracknell, A. P., Huete, A. R., Idris, N. H., Lau, A. M. S., Abd Rahman, M. Z., Rasib, A. W. & Ahmad, A., 18 Jan 2018, In : Singapore Journal of Tropical Geography. 39, 1, p. 90-106 17 p.

Research output: Contribution to journalArticle

tropical forest
Malaysia
aboveground biomass
ecology
Values
Open Access
File
historical perspective
ecosystem service
catchment
habitat
natural capital
1 Citations

Association between a common missense variant in LOXL3 gene and the risk of non-syndromic cleft palate

Khan, M. F. J., Little, J., Mossey, P., Steegers-Theunissen, R. P. M., Bonsi, M., Andreasi, R. B. & Rubini, M., 3 Jul 2018, In : Congenital Anomalies. 58, 4, p. 136-140 5 p.

Research output: Contribution to journalArticle

Cleft Palate
Protein-Lysine 6-Oxidase
Genes
Homozygote
Genotype
Cholinergic Antagonists
Scotland
Hypnotics and Sedatives
Opioid Analgesics
Cohort Studies
2 Citations

Association of opioid prescribing practices with chronic pain and benzodiazepine co-prescription: a primary care data linkage study

Torrance, N., Mansoor, R., Wang, H., Gilbert, S., Macfarlane, G. J., Serpell, M., Baldacchino, A., Hales, T. G., Donnan, P., Wyper, G., Smith, B. H. & Colvin, L., Jun 2018, In : British Journal of Anaesthesia. 120, 6, p. 1345-1355 11 p.

Research output: Contribution to journalArticle

Information Storage and Retrieval
Benzodiazepines
Chronic Pain
Opioid Analgesics
Prescriptions

Association of prolactin receptor (PRLR) variants with prolactinomas

Gorvin, C. M., Newey, P. J., Rogers, A., Stokes, V., Neville, M. J., Lines, K. E., Ntali, G., Lees, P., Morrison, P. J., Singhellakis, P. N., Malandrinou, F. C., Karavitaki, N., Grossman, A. B., Karpe, F. & Thakker, R. V., 15 Nov 2018, In : Human Molecular Genetics. ddy396.

Research output: Contribution to journalArticle

Open Access
File
Prolactin Receptors
Prolactinoma
STAT5 Transcription Factor
Janus Kinase 2
Cytokine Receptors

Associations between back pain across adulthood and spine shape in early old age in a British birth cohort

Muthuri, S. G., Pavlova, A. V., Saunders, F. R., Hardy, R. J., Gregory, J. S., Barr, R. J., Martin, K. R., Adams, J. E., Kuh, D., Aspden, R. M. & Cooper, R., 5 Nov 2018, In : Scientific Reports. 8, 10 p., 16309.

Research output: Contribution to journalArticle

Open Access
File
Back Pain
Spine
Parturition
Linear Models
Health Surveys

Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure (from BIOSTAT-CHF)

Suzuki, T., Yazaki, Y., Voors, A. A., Jones, D. J. L., Chan, D. C. S., Anker, S. D., Cleland, J. G. F., Dickstein, K., Filippatos, G. S., Hillege, H. L., Lang, C., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M. & Ng, L. L., 29 Oct 2018, In : European Journal of Heart Failure. 10 p.

Research output: Contribution to journalArticle

Heart Failure
Guidelines
Therapeutics
Brain Natriuretic Peptide
Confidence Intervals

Asthma Step-Down Strategies: Perhaps the Patient Should Decide?

Lipworth, B. & Israel, E., Mar 2018, In : The Journal of Allergy and Clinical Immunology: In Practice. 6, 2, p. 644-645 2 p.

Research output: Contribution to journalArticle

A strategic action fields perspective on organizational trust repair

Bozic, B., Siebert, S. & Martin, G., 3 May 2018, In : European Management Journal.

Research output: Contribution to journalArticle

Organizational trust
Trust repair
Strategic action
Scandal
Industry
1 Citations

A structural study of the complex between neuroepithelial cell transforming gene 1 (Net1) and RhoA reveals a potential anticancer drug hot spot

Petit, A-P., Garcia-Petit, C., Bueren-Calabuig, J. A., Vuillard, L. M., Ferry, G. & Boutin, J. A., 8 Jun 2018, In : Journal of Biological Chemistry. 293, 23, p. 9064-9077 14 p.

Research output: Contribution to journalArticle

Open Access
File
Neuroepithelial Cells
Oncogenes
Genes
Peptides
Guanine Nucleotide Exchange Factors

A study of the visual symptoms in two-dimensional versus three-dimensional laparoscopy

El Boghdady, M., Ramakrishnan, G. & Alijani, A., 3 Aug 2018, In : American Journal of Surgery. p. 1-4 4 p.

Research output: Contribution to journalArticle

Laparoscopy
Exercise
Asthenopia
Aptitude
Dizziness
1 Citations

A survey of uranium levels in urine and hair of people living in a coal mining area in Yili, Xinjiang, China

Wufuer, R., Song, W., Zhang, D., Pan, X. & Gadd, G. M., Sep 2018, In : Journal of Environmental Radioactivity. 189, p. 168-174 7 p.

Research output: Contribution to journalArticle

Coal Mining
Uranium
coal mining
Coal mines
hair
Asymptotic Solution
Suction
Reynolds number
Transverse
Magnetic Field

A systematic review of clinical trial registration in major respiratory journals 2010-2018

Suntila, N. S., Smith, A., Al-Dabbagh, Y. & Chalmers, J. D., 27 Sep 2018, In : European Respiratory Journal.

Research output: Contribution to journalArticle

Randomized Controlled Trials
Clinical Trials
Publication Bias
Practice Guidelines
Research

A tale of two eras: Phytoplankton composition influenced by oceanic paleochemistry

Giordano, M., Olivieri, C., Ratti, S., Norici, A., Raven, J. A. & Knoll, A. H., Sep 2018, In : Geobiology. 16, 5, p. 498-506 9 p.

Research output: Contribution to journalArticle

chemistry
phytoplankton
oceans
algae
biomass
2 Citations

ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A

Wan, X., Serrill, J. D., Humphreys, I. R., Tan, M., McPhail, K. L., Ganley, I. G. & Ishmael, J. E., 1 Mar 2018, In : Marine Drugs. 16, 3, p. 1-20 20 p., 77.

Research output: Contribution to journalArticle

Open Access
File
Depsipeptides
Autophagy
Thapsigargin
Biological Products
Fibroblasts
2 Citations

Atg7-Mediated Autophagy Is Involved in the Neural Crest Cell Generation in Chick Embryo

Wang, G., Chen, E., Liang, C., Liang, J., Gao, L., Chuai, M., Münsterberg, A., Bao, Y., Cao, L. & Yang, X., Apr 2018, In : Molecular Neurobiology. 55, 4, p. 3523-3536 14 p.

Research output: Contribution to journalArticle

Open Access
File
Neural Crest
Autophagy
Chick Embryo
Neural Tube
Transfection
5 Citations

A treatise for energy law

Heffron, R., Rønne, A., Tomain, J. P., Bradbrook, A. & Talus, K., 8 Mar 2018, In : Journal of World Energy Law & Business. 11, 1, p. 34-48 15 p.

Research output: Contribution to journalArticle

Open Access
File
energy
Carbon
Law
paradigm shift
paradigm
1 Citations

Attitudes and perceptions of health professionals towards management of hypothyroidism in general practice: a qualitative interview study

Dew, R., King, K., Okosieme, O. E., Pearce, S. H., Donovan, G., Taylor, P. N., Hickey, J., Dayan, C. M., Leese, G., Razvi, S. & Wilkes, S., 21 Feb 2018, In : BMJ Open. 8, 2, p. 1-10 10 p., e019970.

Research output: Contribution to journalArticle

Open Access
File
Attitude to Health
Hypothyroidism
General Practice
Thyroxine
Interviews

A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody-Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy

Grubb, A. L., McDonald, T. J., Rutters, F., Donnelly, L., Hattersley, A. T., Oram, R. A., Palmer, C., van der Heijden, A. A., Carr, F., Elders, P. J. M., Weedon, M., Slieker, R. C., 't Hart, L. M., Pearson, E., Shields, B. M. & Jones, A. G., 23 Oct 2018, In : Diabetes Care. p. 1-7 7 p., dc180431.

Research output: Contribution to journalArticle

Open Access
File
Type 1 Diabetes Mellitus
Autoantibodies
Type 2 Diabetes Mellitus
Insulin
Therapeutics
1 Citations

Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest

Allan, L. A., Skowyra, A., Rogers, K. I., Zeller, D. & Clarke, P. R., 3 Sep 2018, In : The EMBO Journal. 37, 17, 15 p., e96831.

Research output: Contribution to journalArticle

Open Access
File
Anaphase-Promoting Complex-Cyclosome
Mitosis
Degradation
Ubiquitin-Protein Ligases
Isoleucine

Augmenting Public Deliberations through Stream Argument Analytics and Visualisations

Plüss, B., Sperrle, F., Gold, V., El-Assady, M., Hautli-Janisz, A., Budzynska, K. & Reed, C., 2018, p. 1-9. 9 p.

Research output: Contribution to conferencePaper

Open Access
File
Visualization
Personal computing
Speech recognition
Communication
1 Citations

A UK nationwide prospective study of treatment change in MODY: genetic subtype and clinical characteristics predict optimal glycaemic control after discontinuing insulin and metformin

Shepherd, M. H., Shields, B. M., Hudson, M., Pearson, E. R., Hyde, C., Ellard, S., Hattersley, A. T. & Patel, K. A., Dec 2018, In : Diabetologia. 61, 12, p. 2520-2527 8 p.

Research output: Contribution to journalArticle

Open Access
File
Metformin
Type 2 Diabetes Mellitus
Prospective Studies
Insulin
Therapeutics
1 Citations

A UK survey of the experience of service provision for children and young people with epilepsy

Williams, F., McCafferty, A., Dunkley, C. & Kirkpatrick, M., 1 Aug 2018, In : Seizure. 60, p. 80-85 6 p.

Research output: Contribution to journalArticle

Epilepsy
Caregivers
Proxy
Quality of Health Care
Child Care

Author Correction: Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates (Scientific Reports DOI: 10.1038/s41598-017-01678-4)

Bartolome, F., Esteras, N., Martin-Requero, A., Boutoleau-Bretonniere, C., Vercelletto, M., Gabelle, A., Ber, I. L., Honda, T., Dinkova-Kostova, A. T., Hardy, J., Carro, E. & Abramov, A. Y., 1 Dec 2018, In : Scientific Reports. 8, p. 1-2 2 p., 4064.

Research output: Contribution to journalComment/debate

Open Access
File
Energy Metabolism
Mutation

Author Correction: A genome scan for milk production traits in dairy goats reveals two new mutations in Dgat1 reducing milk fat content (Scientific Reports DOI: 10.1038/s41598-017-02052-0)

Martin, P., Palhière, I., Maroteau, C., Bardou, P., Canale-Tabet, K., Sarry, J., Woloszyn, F., Bertrand-Michel, J., Racke, I., Besir, H., Rupp, R. & Tosser-Klopp, G., 1 Mar 2018, In : Scientific Reports. 8, p. 1-2 2 p., 4060.

Research output: Contribution to journalComment/debate

Open Access
File
Organized Financing
Goats
Milk
Fats
Organizations
Open Access
File
Centrosome
Neoplasms

Autologous In-labelled platelet scan as a predictor of splenectomy outcome in ITP

Kazi, S., Mckiddie, F., Anderson, J., Bagot, C., Duncan, C., Drummond, M., Kerr, R., Khan, M., McColl, M., Roddie, H., Priddee, N., Staff, R., Thomas, R. & Watson, H. G., 20 Apr 2018, In : British Journal of Haematology.

Research output: Contribution to journalLetter

3 Citations

Automated Unbounded Verification of Stateful Cryptographic Protocols with Exclusive OR

Dreier, J., Hirschi, L., Radomirović, S. & Sasse, R., 7 Aug 2018, 2018 IEEE 31st Computer Security Foundations Symposium (CSF). 31st ed. IEEE, p. 359-373 15 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
Network protocols
Radio frequency identification (RFID)

Automatic Brain Labeling via Multi-Atlas Guided Fully Convolutional Networks

Fang, L., Zhang, L., Nie, D., Cao, X., Rekik, I., Lee, S-W., He, H. & Shen, D., 1 Nov 2018, In : Medical Image Analysis. 51, p. 157-168 12 p.

Research output: Contribution to journalArticle

Atlases
Labeling
Brain
Neuroimaging
Learning

Axillary tumour burden in women with one abnormal node on ultrasound compared to women with multiple abnormal nodes

Puri, S., Sharma, N., Newcombe, R. G., Kaushik, M., Al-Attar, M., Pascaline, S., Hajaj, M., Wallis, M. G., Elsberger, B. & Goyal, A., Apr 2018, In : Clinical Radiology. 73, 4, p. 391-395 5 p.

Research output: Contribution to journalArticle

Tumor Burden
Lymph Node Excision
Needle Biopsy
Neoplasm Metastasis
Histology
3 Citations

Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice

Meakin, P. J., Jalicy, S. M., Montagut, G., Allsop, D. J. P., Cavellini, D. L., Irvine, S. W., McGinley, C., Liddell, M. K., McNeilly, A. D., Parmionova, K., Liu, Y-R., Bailey, C. S. L., Dale, J. K., Heisler, L. K., McCrimmon, R. J. & Ashford, M. L. J., 8 Jan 2018, In : Scientific Reports. 8, 1, p. 55 16 p., 55.

Research output: Contribution to journalArticle

Open Access
File
Obese Mice
Leptin
Amyloid
Obesity
Homeostasis
13 Citations

BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease

Prati, F., Bottegoni, G., Bolognesi, M. L. & Cavalli, A., 8 Feb 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 619-637 19 p.

Research output: Contribution to journalReview article

Open Access
File
Alzheimer Disease
Drug Discovery
Amyloid
Amyloid beta-Protein Precursor
Pharmaceutical Preparations

Background Paper: Human Rights and Prevention of Violent Extremism - 18th Informal ASEM Seminar on Human Rights

Gavrielides, T., Santiago, I., Filippon, N., Kwokori, A., Natividade, S. & Jalgaonkar, S., 5 Nov 2018. 78 p.

Research output: Contribution to conferencePaper