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2010

Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor

Maertens, G. N., El Messaoudi-Aubert, S., Elderkin, S., Hiom, K. & Peters, G., 4 Aug 2010, In : EMBO Journal. 29, 15, p. 2553-2565 13 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)
2009

Use of insulin glargine and cancer incidence in Scotland: a study from the Scottish Diabetes Research Network Epidemiology Group

Colhoun, H. M. & Scottish Diabetes Research Network Epidemiology Group, Sep 2009, In : Diabetologia. 52, 9, p. 1755-1765 11 p.

Research output: Contribution to journalArticle

322 Citations (Scopus)
2013

AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In : Cell Metabolism. 18, 4, p. 556-566 11 p.

Research output: Contribution to journalArticle

Open Access
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235 Citations (Scopus)
107 Downloads (Pure)
2014

Neuropathic pain in the general population: a systematic review of epidemiological studies

van Hecke, O., Austin, S. K., Khan, R. A., Smith, B. H. & Torrance, N., Apr 2014, In : Pain. 155, 4, p. 654-662 9 p.

Research output: Contribution to journalArticle

393 Citations (Scopus)

Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection

Hodson, C., Purkiss, A., Miles, J. A. & Walden, H., Feb 2014, In : Structure. 22, 2, p. 337-344

Research output: Contribution to journalArticle

Open Access
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44 Citations (Scopus)
283 Downloads (Pure)
2013

Loss of iron triggers PINK1/Parkin-independent mitophagy

Allen, G. F. G., Toth, R., James, J. & Ganley, I. G., 2013, In : EMBO Reports. 14, p. 1127-1135 9 p.

Research output: Contribution to journalArticle

177 Citations (Scopus)

Medical management of critical limb ischaemia: where do we stand today?

Lambert, M. A. & Belch, J. J. F., Oct 2013, In : Journal of Internal Medicine. 274, 4, p. 295-307 13 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells

Ulvestad, M., Nordell, P., Asplund, A., Rehnström, M., Jacobsson, S., Holmgren, G., Davidson, L., Brolén, G., Edsbagge, J., Björquist, P., Küppers-Munther, B. & Andersson, T. B., 1 Sep 2013, In : Biochemical Pharmacology. 86, 5, p. 691-702 12 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)
2005

Trends in peer learning

Topping, K. J., Dec 2005, In : Educational Psychology. 25, 6, p. 631-645 15 p.

Research output: Contribution to journalArticle

558 Citations (Scopus)
1996

Mechanism of activation of protein kinase B by insulin and IGF-1

Alessi, D. R., Andjelkovic, M., Caudwell, B., Cron, P., Morrice, N., Cohen, P. & Hemmings, B. A., 1996, In : EMBO Journal. 15, 23, p. 6541-6551 11 p.

Research output: Contribution to journalArticle

2323 Citations (Scopus)
1994

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hunt, T. & Nebreda, A. R., 23 Sep 1994, In : Cell. 78, 6, p. 1027-1037 11 p.

Research output: Contribution to journalArticle

1442 Citations (Scopus)
2014

Constructing identities in the media: newspaper coverage analysis of a major UK Clostridium difficile outbreak

Burnett, E., Johnston, B., Corlett, J. & Kearney, N., Jul 2014, In : Journal of Advanced Nursing. 70, 7, p. 1542-1552 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

Renal tumors: diagnostic and prognostic biomarkers

Tan, P. H., Cheng, L., Rioux-Leclercq, N., Merino, M. J., Netto, G., Reuter, V. E., Shen, S. S., Grignon, D. J., Montironi, R., Egevad, L., Srigley, J. R., Delahunt, B., Moch, H. & ISUP Renal Tumor Panel, Oct 2013, In : American Journal of Surgical Pathology. 37, 10, p. 1518–1531 14 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)
2014

A role for cytochrome b5 in the in vivo disposition of anti-cancer and cytochrome P450 probe drugs in mice

Henderson, C. J., McLaughlin, L. A., Finn, R. D., Ronseaux, S., Kapelyukh, Y. & Wolf, C. R., Jan 2014, In : Drug Metabolism and Disposition. 42, 1, p. 70-77 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2013

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

Fullerton, M. D., Galic, S., Marcinko, K., Sikkema, S., Pulinilkunnil, T., Chen, Z-P., O'Neill, H. M., Ford, R. J., Palanivel, R., O'Brien, M., Hardie, D. G., Macaulay, S. L., Schertzer, J. D., Dyck, J. R. B., van Denderen, B. J., Kemp, B. E. & Steinberg, G. R., 2013, In : Nature Medicine. 19, p. 1649-1654 6 p.

Research output: Contribution to journalArticle

303 Citations (Scopus)

Top 10 plant-parasitic nematodes in molecular plant pathology

Jones, J. T., Haegeman, A., Danchin, E. G. J., Gaur, H. S., Helder, J., Jones, M. G. K., Kikuchi, T., Manzanilla-López, R., Palomares-Rius, J. E., Wesemael, W. M. L. & Perry, R. N., Dec 2013, In : Molecular Plant Pathology. 14, 9, p. 946-961 16 p.

Research output: Contribution to journalArticle

455 Citations (Scopus)
2012

Natural variation in a homolog of Antirrhinum CENTRORADIALIS contributed to spring growth habit and environmental adaptation in cultivated barley

Comadran, J., Kilian, B., Russell, J., Ramsay, L., Stein, N., Ganal, M., Shaw, P., Bayer, M., Thomas, W., Marshall, D., Hedley, P., Tondelli, A., Pecchioni, N., Francia, E., Korzun, V., Walther, A. & Waugh, R., Dec 2012, In : Nature Genetics. 44, 12, p. 1388-1392 5 p.

Research output: Contribution to journalLetter

250 Citations (Scopus)
2013
76 Citations (Scopus)

Small RNAs derived from the 5' end of tRNA can inhibit protein translation in human cells

Sobala, A. & Hutvagner, G., Apr 2013, In : RNA Biology. 10, 4, p. 553-563 11 p.

Research output: Contribution to journalArticle

124 Citations (Scopus)
2014

Biosorption: current perspectives on concept, definition and application

Fomina, M. & Gadd, G. M., May 2014, In : Bioresource Technology. 160, p. 3-14 12 p.

Research output: Contribution to journalArticle

371 Citations (Scopus)
2013

Caffeoyl shikimate esterase (CSE) is an enzyme in the lignin biosynthetic pathway in Arabidopsis

Vanholme, R., Cesarino, I., Rataj, K., Xiao, Y., Sundin, L., Goeminne, G., Kim, H., Cross, J., Morreel, K., Araujo, P., Welsh, L., Haustraete, J., McClellan, C., Vanholme, B., Ralph, J., Simpson, G. G., Halpin, C. & Boerjan, W., 6 Sep 2013, In : Science. 341, 6150, p. 1103-1106 4 p.

Research output: Contribution to journalArticle

207 Citations (Scopus)

Mitogen-activated protein kinases in innate immunity

Arthur, J. S. C. & Ley, S. C., Sep 2013, In : Nature Reviews Immunology. 13, 9, p. 679-692 14 p.

Research output: Contribution to journalArticle

652 Citations (Scopus)
1995

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

Alessi, D. R., Cuenda, A., Cohen, P., Dudley, D. T. & Saltiel, A. R., 17 Nov 1995, In : Journal of Biological Chemistry. 270, 46, p. 27489-27494 6 p.

Research output: Contribution to journalArticle

3057 Citations (Scopus)
2010

Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif

Matic, I., Schimmel, J., Hendriks, I. . A., van Santen, M. A., van de Rijke, F., van Dam, H., Gnad, F., Mann, M. & Vertegaal, A. C. O., 27 Aug 2010, In : Molecular Cell. 39, 4, p. 641-652 12 p.

Research output: Contribution to journalArticle

183 Citations (Scopus)
2012

Soil-foundation-structure interaction with mobilization of bearing capacity: experimental study on sand

Drosos, V., Georgarakos, T., Loli, M., Anastasopoulos, I., Zarzouras, O. & Gazetas, G., Nov 2012, In : Journal of Geotechnical and Geoenvironmental Engineering. 138, 11, p. 1369-1386 18 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2011

Identification of RhoGAP22 as an Akt-dependent regulator of cell motility in response to insulin

Rowland, A. F., Larance, M., Hughes, W. E. & James, D. E., Dec 2011, In : Molecular and Cellular Biology. 31, 23, p. 4789-4800 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2013

The International Society of Urological Pathology (ISUP) grading system for renal cell carcinoma and other prognostic parameters

Delahunt, B., Cheville, J. C., Martignoni, G., Humphrey, P. A., Magi-Galluzzi, C., McKenney, J., Egevad, L., Algaba, F., Moch, H., Grignon, D. J., Montrioni, R., Srigley, J. R. & ISUP Renal Tumor Panel, Oct 2013, In : American Journal of Surgical Pathology. 37, 10, p. 1490–1504 15 p.

Research output: Contribution to journalArticle

312 Citations (Scopus)
2011

Long waves through emergent coastal vegetation

Mei, C. C., Chan, I-C., Liu, P. L-F., Huang, Z. & Zhang, W., 25 Nov 2011, In : Journal of Fluid Mechanics. 687, p. 461-491 31 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2012

Germline Mutation in EXPH5 Implicates the Rab27B Effector Protein Slac2-b in Inherited Skin Fragility

McGrath, J. A., Stone, K. L., Begum, R., Simpson, M. A., Dopping-Hepenstal, P. J., Liu, L., McMillan, J. R., South, A. P., Pourreyron, C., McLean, W. H. I., Martinez, A. E., Mellerio, J. E. & Parsons, M., 7 Dec 2012, In : American Journal of Human Genetics. 91, 6, p. 1115-1121 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2005

The photocarcinogenic risk of narrowband UVB (TL-01) phototherapy: early follow-up data

Man, I., Crombie, I. K., Dawe, R. S., Ibbotson, S. H. & Ferguson, J., Apr 2005, In : The British journal of dermatology. 152, 4, p. 755-757 3 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)
2003

A randomized controlled trial (volunteer study) of sitafloxacin, enoxacin, levofloxacin and sparfloxacin phototoxicity

Dawe, R. S., Ibbotson, S. H., Sanderson, J. B., Thomson, E. M. & Ferguson, J., 2003, In : The British journal of dermatology. 149, 6, p. 1232-1241 10 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2013
94 Citations (Scopus)
1995

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Cross, D. A. E., Alessi, D. R., Cohen, P., Andjelkovich, M. & Hemmings, B. A., 28 Dec 1995, In : Nature. 378, p. 785-789 5 p.

Research output: Contribution to journalLetter

3969 Citations (Scopus)
2013

Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes

Narlikar, G. J., Sundaramoorthy, R. & Owen-Hughes, T., 2013, In : Cell. 154, 3, p. 490-503 14 p.

Research output: Contribution to journalArticle

281 Citations (Scopus)
2010

Howdo Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?

Labib, K., 15 Jun 2010, In : Genes & Development. 24, 12, p. 1208-1219 12 p.

Research output: Contribution to journalArticle

226 Citations (Scopus)
2013

The interferon response to intracellular DNA: Why so many receptors?

Unterholzner, L., Nov 2013, In : Immunobiology. 218, 11, p. 1312-1321 10 p.

Research output: Contribution to journalArticle

137 Citations (Scopus)
1996

The effectiveness of peer tutoring in further and higher education: A typology and review of the literature

Topping, K. J., Oct 1996, In : Higher Education. 32, 3, p. 321-345 25 p.

Research output: Contribution to journalArticle

485 Citations (Scopus)
2007
615 Citations (Scopus)
2008

Management of granular myringitis: a systematic review

Neilson, L. J. & Hussain, S. S. M., 2008, In : Journal of Laryngology and Otology. 122, 1, p. 3-10 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2014

Energy costs of carbon dioxide concentrating mechanisms in aquatic organisms

Raven, J. A., Beardall, J. & Giordano, M., Sep 2014, In : Photosynthesis Research. 121, 2-3, p. 111-124 14 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Accuracy of dental age estimation charts: Schour and Massler, Ubelaker and the London Atlas

Alqahtani, S. J., Hector, M. P. & Liversidge, H. M., May 2014, In : American Journal of Physical Anthropology. 154, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2007

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

Hardie, D. G., Oct 2007, In : Nature Reviews Molecular Cell Biology. 8, 10, p. 774-85 12 p.

Research output: Contribution to journalArticle

1494 Citations (Scopus)
2014
10 Citations (Scopus)
2016

Managing carious lesions: consensus recommendations on carious tissue removal

Schwendicke, F., Frencken, J. E., Bjørndal, L., Maltz, M., Manton, D. J., Ricketts, D., Van Landuyt, K., Banderjee, A., Campus, G., Doméjean, S., Fontana, M., Leal, S., Lo, E., Machiulskiene, V., Schulte, A., Splieth, C., Zandona, A. F. & Innes, N. P. T., May 2016, In : Advances in Dental Research: an E-Supplement to Journal of Dental Research. 28, 2, p. 58-67 10 p.

Research output: Contribution to journalArticle

Open Access
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169 Citations (Scopus)
273 Downloads (Pure)

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?

Schurch, N. J., Schofield, P., Gierliński, M., Cole, C., Sherstnev, A., Singh, V., Wrobel, N., Gharbi, K., Simpson, G. G., Owen-Hughes, T., Blaxter, M. & Barton, G. J., Jun 2016, In : RNA: a Publication of the RNA Society. 22, 6, p. 839-851 13 p.

Research output: Contribution to journalArticle

Open Access
File
185 Citations (Scopus)
175 Downloads (Pure)
2014

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters

De Los Heros, P., Alessi, D. R., Gourlay, R., Campbell, D. G., Deak, M., Macartney, T. J., Kahle, K. T. & Zhang, J., 15 Mar 2014, In : Biochemical Journal. 458, 3, p. 559-573 15 p.

Research output: Contribution to journalArticle

Open Access
File
90 Citations (Scopus)
154 Downloads (Pure)
2015

Home blood pressure monitoring

George, J. & MacDonald, T., 2015, In : European Cardiology Review. 10, 2, p. 95-101 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2016

Impact of socioeconomic status on disease phenotype, genomic landscape and outcomes in myelodysplastic syndromes

Mastaglio, F., Bedair, K., Papaemmanuil, E., Groves, M. J., Hyslop, A., Keenan, N., Hothersall, E. J., Campbell, P. J., Bowen, D. T. & Tauro, S., Jul 2016, In : British Journal of Haematology. 174, 2, p. 227-234 8 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
146 Downloads (Pure)

Genome-wide association study identifies 74 loci associated with educational attainment

Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G-B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., de Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G. & 31 others, Brandsma, J. H., Pina Concas, M., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., van der Lee, S. J., deLeeuw, C., Lind, P. A., Lindgren, K-O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., van der Most, P. J., Oldmeadow, C., Payton, A., Smith, B. H. & LifeLines Cohort Study, 26 May 2016, In : Nature. 533, 7604, p. 539-542 4 p.

Research output: Contribution to journalLetter

Open Access
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408 Citations (Scopus)
76 Downloads (Pure)