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Article

A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation

Minutti, C. M., Modak, R. V., Macdonald, F., Li, F., Smyth, D. J., Dorward, D. A., Blair, N., Husovsky, C., Muir, A., Giampazolias, E., Dobie, R., Maizels, R. M., Kendall, T. J., Griggs, D. W., Kopf, M., Henderson, N. C. & Zaiss, D. M., 19 Mar 2019, In : Immunity. 50, 3, p. 645-654.e6

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

A matched comparison study of hepatitis C treatment outcomes in the prison and community setting, and an analysis of the impact of prison release or transfer during therapy

Aspinall, E. J., Mitchell, W., Schofield, J., Cairns, A., Lamond, S., Bramley, P., Peters, S. E., Valerio, H., Tomnay, J., Goldberg, D. J., Mills, P. R., Barclay, S. T., Fraser, A., Dillon, J. F., Martin, N. K., Hickman, M. & Hutchinson, S. J., Dec 2016, In : Journal of Viral Hepatitis. 23, 12, p. 1009-1016 8 p.

Research output: Contribution to journalArticle

Open Access
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21 Citations (Scopus)
158 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
88 Downloads (Pure)

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis

Naeem, A. S., Tommasi, C., Cole, C., Brown, S. J., Zhu, Y., Way, B., Willis Owen, S. A. G., Moffatt, M., Cookson, W. O., Harper, J. I., Di, W. L., Brown, S. J., Reinheckel, T. & O'Shaughnessy, R. F. L., Apr 2017, In : Journal of Allergy and Clinical Immunology. 139, 4, p. 1228-1241 14 p.

Research output: Contribution to journalArticle

Open Access
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7 Citations (Scopus)
192 Downloads (Pure)

A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function

Casanova, F., Wood, A. R., Yaghootkar, H., Beaumont, R. N., Jones, S. E., Gooding, K. M., Aizawa, K., Strain, W. D., Hattersley, A. T., Khan, F., Shore, A. C., Frayling, T. M. & Tyrrell, J., May 2020, In : Diabetes. 69, 5, p. 1072-1082 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
114 Downloads (Pure)
Open Access
File
4 Citations (Scopus)
177 Downloads (Pure)

A method for automatic segmentation and splitting of hyperspectral images of raspberry plants collected in field conditions

Williams, D., Britten, A., McCallum, S., Jones, H., Aitkenhead, M., Karley, A., Loades, K., Prashar, A. & Graham, J., 1 Nov 2017, In : Plant Methods. 13, p. 1-12 12 p., 74.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
141 Downloads (Pure)

A methodological approach to assess the hazard of underground cavities subjected to environmental weathering

Castellanza, R., Lollino, P. & Ciantia, M., Dec 2018, In : Tunnelling and Underground Space Technology. 82, p. 278-292 15 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

A Method to Evaluate Trainee Progression During Simulation Training at the Urology Simulation Boot Camp (USBC) Course

Kailavasan, M., Hanchanale, V., Rajpal, S., Morley, R., Mcllhenny, C., Somani, B., Nabi, G., Gowda, R., Jain, S., Biyani, C. S. & Myatt, A., Jan 2019, In : Journal of Surgical Education. 76, 1, p. 215-222 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Amine Containing Analogs of Sulindac for Cancer Prevention

Mathew, B., Hobrath, J. V., Connelly, M. C., Guy, R. K. & Reynolds, R. C., 31 Jan 2018, In : Open Medicinal Chemistry Journal. 12, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
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128 Downloads (Pure)

A minimally invasive tool to study immune response and skin barrier in children with atopic dermatitis

Hulshof, L., Hack, D. P., Hasnoe, Q. C. J., Dontje, B., Jakasa, I., Riethmüller, C., McLean, W. H. I., van Aalderen, W. M. C., Van't Land, B., Kezic, S., Sprikkelman, A. B. & Middelkamp-Hup, M. A., Mar 2019, In : British Journal of Dermatology. 180, 3, p. 621-630 10 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
93 Downloads (Pure)

A mink-free GB: perspectives on eradicating American mink Neovison vison from Great Britain and its islands

Martin, A. R. & Lea, V. J., 1 Apr 2020, In : Mammal Review. 50, 2, p. 170-179 10 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
40 Downloads (Pure)

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

Loftus, R. M., Assmann, N., Kedia-Mehta, N., O'Brien, K. L., Garcia, A., Gillespie, C., Hukelmann, J. L., Oefner, P. J., Lamond, A. I., Gardiner, C. M., Dettmer, K., Cantrell, D. A., Sinclair, L. V. & Finlay, D. K., 14 Jun 2018, In : Nature Communications. 9, 1, p. 1-15 15 p., 2341.

Research output: Contribution to journalArticle

Open Access
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36 Citations (Scopus)
141 Downloads (Pure)
Open Access
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4 Citations (Scopus)
76 Downloads (Pure)

Amino acid substitutions in the human homomeric β3 GABAA receptor that enable activation by GABA

Gottschald Chiodi, C., Baptista-Hon, D., Hunter, W. & Hales, T., 15 Feb 2019, In : Journal of Biological Chemistry. 294, 7, p. 2375-2385 11 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
82 Downloads (Pure)

A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability

Pravata, V. M., Gundogdu, M., Bartual, S. G., Ferenbach, A. T., Stavridis, M., Õunap, K., Pajusalu, S., Žordania, R., Wojcik, M. H. & van Aalten, D. M. F., 7 Nov 2019, In : FEBS Letters.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A Mixed Analytical/Numerical Method for Velocity and Heat Transfer of Laminar Power-Law Fluids

Li, B., Zheng, L., Lin, P., Wang, Z. & Liao, M., 3 Aug 2016, In : Numerical Mathematics: Theory, Methods and Applications. 9, 3, p. 315-336 22 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
Open Access
File
29 Downloads (Pure)
Open Access
File
2 Citations (Scopus)
150 Downloads (Pure)

A Model for (Quasi-)Periodic Multiwavelength Photometric Variability in Young Stellar Objects

Kesseli, A. Y., Petkova, M. A., Wood, K., Whitney, B. A., Hillenbrand, L. A., Gregory, S. G., Stauffer, J. R., Morales-Calderon, M., Rebull, L. & Alencar, S. H. P., Sep 2016, In : Astrophysical Journal. 828, 1, p. 1-15 15 p., 42.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
62 Downloads (Pure)

A model of consultation in prostate cancer care: evidence from a systematic review

Paterson, C. & Nabi, G., 2017, In : Cancer Nursing. 40, 4, p. 276-288 13 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
224 Downloads (Pure)
1 Citation (Scopus)

A modified Delphi process to establish future research priorities in malignant oesophagogastric surgery

Wilson, M. S. J., Blencowe, N. S., Boyle, C., Knight, S. R., Petty, R., Vohra, R. S. & Underwood, T. J., 16 Dec 2019, In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6 p.

Research output: Contribution to journalArticle

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors

Harrison, J. R., Brand, S., Smith, V., Robinson, D. A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L. S., Collie, I., Hallyburton, I., Norval, S., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Brenk, R., Wyatt, P. G., Gilbert, I. H. & Read, K. D., 12 Sep 2018, In : Journal of Medicinal Chemistry. 61, 18, p. 8374–8389 16 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
164 Downloads (Pure)
Open Access
File
2 Citations (Scopus)
85 Downloads (Pure)

A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells

Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In : Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
314 Downloads (Pure)

A moving interface finite element formulation for layered structures

Funari, M. F., Greco, F. & Lonetti, P., 1 Jul 2016, In : Composites Part B: Engineering. 96, p. 325-337 13 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

AMP-activated protein kinase: a cellular energy sensor that comes in twelve flavours

Ross, F. A., MacKintosh, C. & Hardie, D. G., 24 Mar 2016, In : FEBS Journal. 283, 16, p. 2987-3001 15 p.

Research output: Contribution to journalArticle

Open Access
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118 Citations (Scopus)
92 Downloads (Pure)

AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner

Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In : Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
246 Downloads (Pure)

AMP-activated protein kinase inhibits Kv1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation

Moral-Sanz, J., Mahmoud, A. D., Ross, F. A., Eldstrom, J., Fedida, D., Hardie, D. G. & Evans, A. M., 1 Sep 2016, In : Journal of Physiology. 594, 17, p. 4901-4915 15 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
132 Downloads (Pure)

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner

Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., Bryant, J. A., Banzhaf, M., Lavery, G. G., Hardie, D. G., Hodson, D. J., Philp, A. & Lai, Y-C., 4 May 2020, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 5, p. 6284-6301 18 p.

Research output: Contribution to journalArticle

Open Access
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47 Downloads (Pure)

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In : Nature Communications. 7, 10856.

Research output: Contribution to journalArticle

Open Access
47 Citations (Scopus)

AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2

Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In : Molecular Cancer Research. 14, 8, p. 683-695 13 p.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
284 Downloads (Pure)

Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study

Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In : Diabetologia. 61, 12, p. 2590-2597 8 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
151 Downloads (Pure)

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, Marten, J., Musani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., Connell, J. M., Smith, B. H., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., 1 Aug 2019, In : Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
15 Downloads (Pure)

A Multicellular Model of Intestinal Crypt Buckling and Fission

Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In : Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
182 Downloads (Pure)

A Multicenter, Randomized, Placebo-Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis: A multicenter, randomized, placebo controlled trial

Kitas, G. D., Nightingale, P., Armitage, J., Sattar, N., Belch, J. J. F. & Symmons, D. P. M., Sep 2019, In : Arthritis and Rheumatology. 71, 9, p. 1437-1449 13 p.

Research output: Contribution to journalArticle

Open Access
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14 Citations (Scopus)
35 Downloads (Pure)

A multi-centre, prospective epidemiological surveillance study considering ophthalmic complications of functional endoscopic sinus surgery

Burgess, S., Foulds, J., White, P., Foot, B. & Macewen, C., Mar 2020, In : Journal of Laryngology and Otology. 134, 3, p. 228-232 5 p.

Research output: Contribution to journalArticle

A multicentre parallel-group randomised trial assessing multiparametric MRI characterisation and image-guided biopsy of prostate in men suspected of having prostate cancer: MULTIPROS study protocol

Szewczyk-Bieda, M., Wei, C., Coll, K., Gandy, S., Donnan, P., Ragupathy, S. K. A., Singh, P., Wilson, J. & Nabi, G., 21 Nov 2019, In : Trials. 20, p. 1-8 8 p., 638.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
51 Downloads (Pure)

A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13

Leslie, E. J., Carlson, J. C., Shaffer, J. R., Feingold, E., Wehby, G., Laurie, C. A., Jain, D., Laurie, C. C., Doheny, K. F., McHenry, T., Resick, J., Sanchez, C., Jacobs, J., Emanuele, B., Vieira, A. R., Neiswanger, K., Lidral, A. C., Valencia-Ramirez, L. C., Lopez-Palacio, A. M., Valencia, D. R. & 35 others, Arcos-Burgos, M., Czeizel, A. E., Field, L. L., Padilla, C. D., Cutiongco-de la Paz, E. M. C., Deleyiannis, F., Christensen, K., Munger, R. G., Lie, R. T., Wilcox, A., Romitti, P. A., Castilla, E. E., Mereb, J. C., Poletta, F. A., Orioli, I. M., Carvalho, F. M., Hecht, J. T., Blanton, S. H., Buxó, C. J., Butali, A., Mossey, P. A., Adeyemo, W. L., James, O., Braimah, R. O., Aregbesola, B. S., Eshete, M. A., Abate, F., Koruyucu, M., Seymen, F., Ma, L., de Salamanca, J. E., Weinberg, S. M., Moreno, L., Murray, J. C. & Marazita, M. L., 1 Jul 2016, In : Human Molecular Genetics. 25, 13, p. 2862-2872 11 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase

Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
134 Downloads (Pure)

A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features

Fetit, A., Doney, A., Hogg, S., Wang, R., MacGillivray, T., Wardlaw, J. M., Doubal, F. N., McKay, G. J., McKenna, S. & Trucco, E., 5 Mar 2019, In : Scientific Reports. 9, 1, p. 1-10 10 p., 3591.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
109 Downloads (Pure)

A multiscale mathematical model of tumour invasive growth

Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In : Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
146 Downloads (Pure)

A multispecialty study of determining the possibility of pregnancy and the documentation of pregnancy status in surgical patients: a cause for concern?

Ibrahim, I., Ibrahim, B., Yong, G. L., Coats, M., Vujovic, Z. & Wilson, M. S. J., 1 Nov 2018, In : Scottish Medical Journal. 63, 4, p. 108-112 5 p.

Research output: Contribution to journalArticle

A mutant O-GlcNAcase enriches Drosophila developmental regulators

Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In : Nature Chemical Biology. 13, 8, p. 882-887 8 p.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
162 Downloads (Pure)

Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease

Pickett, E. K., Herrmann, A. G., McQueen, J., Abt, K., Dando, O., Tulloch, J., Jain, P., Dunnett, S., Sohrabi, S., Fjeldstad, M. P., Calkin, W., Murison, L., Jackson, R. J., Tzioras, M., Stevenson, A., d'Orange, M., Hooley, M., Davies, C., Colom-Cadena, M., Anton-Fernandez, A. & 10 others, King, D., Oren, I., Rose, J., McKenzie, C. A., Allison, E., Smith, C., Hardt, O., Henstridge, C. M., Hardingham, G. E. & Spires-Jones, T. L., 10 Dec 2019, In : Cell Reports. 29, 11, p. 3592-3604.e5

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
42 Downloads (Pure)

Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity

Cuthbertson, D. J., Babraj, J., Leese, G. & Siervo, M., Dec 2017, In : Clinical Nutrition. 36, 6, p. 1716-1719 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

An acute transfusion reaction

Webb, C., Norris, A. & Hands, K., 1 Feb 2018, In : Clinical Medicine - Journal of the Royal College of Physicians of London. 18, 1, p. 95-97 3 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Anaesthesia for laryngo-tracheal surgery, including tubeless field techniques

Pearson, K. L. & McGuire, B. E., 1 Jul 2017, In : BJA Education. 17, 7, p. 242-248 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)