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Article

A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability

Pravata, V. M., Gundogdu, M., Bartual, S. G., Ferenbach, A. T., Stavridis, M., Õunap, K., Pajusalu, S., Žordania, R., Wojcik, M. H. & van Aalten, D. M. F., 7 Nov 2019, In : FEBS Letters.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A Mixed Analytical/Numerical Method for Velocity and Heat Transfer of Laminar Power-Law Fluids

Li, B., Zheng, L., Lin, P., Wang, Z. & Liao, M., 3 Aug 2016, In : Numerical Mathematics: Theory, Methods and Applications. 9, 3, p. 315-336 22 p.

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6 Citations (Scopus)
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18 Downloads (Pure)
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146 Downloads (Pure)

A Model for (Quasi-)Periodic Multiwavelength Photometric Variability in Young Stellar Objects

Kesseli, A. Y., Petkova, M. A., Wood, K., Whitney, B. A., Hillenbrand, L. A., Gregory, S. G., Stauffer, J. R., Morales-Calderon, M., Rebull, L. & Alencar, S. H. P., Sep 2016, In : Astrophysical Journal. 828, 1, p. 1-15 15 p., 42.

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Open Access
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7 Citations (Scopus)
60 Downloads (Pure)

A model of consultation in prostate cancer care: evidence from a systematic review

Paterson, C. & Nabi, G., 2017, In : Cancer Nursing. 40, 4, p. 276-288 13 p.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
216 Downloads (Pure)
1 Citation (Scopus)

A modified Delphi process to establish future research priorities in malignant oesophagogastric surgery

Wilson, M. S. J., Blencowe, N. S., Boyle, C., Knight, S. R., Petty, R., Vohra, R. S. & Underwood, T. J., 16 Dec 2019, In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6 p.

Research output: Contribution to journalArticle

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors

Harrison, J. R., Brand, S., Smith, V., Robinson, D. A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L. S., Collie, I., Hallyburton, I., Norval, S., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Brenk, R., Wyatt, P. G., Gilbert, I. H. & Read, K. D., 12 Sep 2018, In : Journal of Medicinal Chemistry. 61, 18, p. 8374–8389 16 p.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
161 Downloads (Pure)
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2 Citations (Scopus)
82 Downloads (Pure)

A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells

Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In : Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
299 Downloads (Pure)

A moving interface finite element formulation for layered structures

Funari, M. F., Greco, F. & Lonetti, P., 1 Jul 2016, In : Composites Part B: Engineering. 96, p. 325-337 13 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

AMP-activated protein kinase: a cellular energy sensor that comes in twelve flavours

Ross, F. A., MacKintosh, C. & Hardie, D. G., 24 Mar 2016, In : FEBS Journal. 283, 16, p. 2987-3001 15 p.

Research output: Contribution to journalArticle

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115 Citations (Scopus)
89 Downloads (Pure)

AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner

Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In : Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.

Research output: Contribution to journalArticle

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10 Citations (Scopus)
235 Downloads (Pure)

AMP-activated protein kinase inhibits Kv1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation

Moral-Sanz, J., Mahmoud, A. D., Ross, F. A., Eldstrom, J., Fedida, D., Hardie, D. G. & Evans, A. M., 1 Sep 2016, In : Journal of Physiology. 594, 17, p. 4901-4915 15 p.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)
128 Downloads (Pure)

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner

Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., Bryant, J. A., Banzhaf, M., Lavery, G. G., Hardie, D. G., Hodson, D. J., Philp, A. & Lai, Y-C., 4 May 2020, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 5, p. 6284-6301 18 p.

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AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In : Nature Communications. 7, 10856.

Research output: Contribution to journalArticle

Open Access
44 Citations (Scopus)

AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2

Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In : Molecular Cancer Research. 14, 8, p. 683-695 13 p.

Research output: Contribution to journalArticle

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29 Citations (Scopus)
283 Downloads (Pure)

Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study

Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In : Diabetologia. 61, 12, p. 2590-2597 8 p.

Research output: Contribution to journalArticle

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10 Citations (Scopus)
142 Downloads (Pure)

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, Marten, J., Musani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., Connell, J. M., Smith, B. H., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., 1 Aug 2019, In : Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.

Research output: Contribution to journalArticle

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A Multicellular Model of Intestinal Crypt Buckling and Fission

Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In : Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
179 Downloads (Pure)

A Multicenter, Randomized, Placebo-Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis: A multicenter, randomized, placebo controlled trial

Kitas, G. D., Nightingale, P., Armitage, J., Sattar, N., Belch, J. J. F. & Symmons, D. P. M., Sep 2019, In : Arthritis and Rheumatology. 71, 9, p. 1437-1449 13 p.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
34 Downloads (Pure)

A multi-centre, prospective epidemiological surveillance study considering ophthalmic complications of functional endoscopic sinus surgery

Burgess, S., Foulds, J., White, P., Foot, B. & Macewen, C., Mar 2020, In : Journal of Laryngology and Otology. 134, 3, p. 228-232 5 p.

Research output: Contribution to journalArticle

A multicentre parallel-group randomised trial assessing multiparametric MRI characterisation and image-guided biopsy of prostate in men suspected of having prostate cancer: MULTIPROS study protocol

Szewczyk-Bieda, M., Wei, C., Coll, K., Gandy, S., Donnan, P., Ragupathy, S. K. A., Singh, P., Wilson, J. & Nabi, G., 21 Nov 2019, In : Trials. 20, p. 1-8 8 p., 638.

Research output: Contribution to journalArticle

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A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13

Leslie, E. J., Carlson, J. C., Shaffer, J. R., Feingold, E., Wehby, G., Laurie, C. A., Jain, D., Laurie, C. C., Doheny, K. F., McHenry, T., Resick, J., Sanchez, C., Jacobs, J., Emanuele, B., Vieira, A. R., Neiswanger, K., Lidral, A. C., Valencia-Ramirez, L. C., Lopez-Palacio, A. M., Valencia, D. R. & 35 others, Arcos-Burgos, M., Czeizel, A. E., Field, L. L., Padilla, C. D., Cutiongco-de la Paz, E. M. C., Deleyiannis, F., Christensen, K., Munger, R. G., Lie, R. T., Wilcox, A., Romitti, P. A., Castilla, E. E., Mereb, J. C., Poletta, F. A., Orioli, I. M., Carvalho, F. M., Hecht, J. T., Blanton, S. H., Buxó, C. J., Butali, A., Mossey, P. A., Adeyemo, W. L., James, O., Braimah, R. O., Aregbesola, B. S., Eshete, M. A., Abate, F., Koruyucu, M., Seymen, F., Ma, L., de Salamanca, J. E., Weinberg, S. M., Moreno, L., Murray, J. C. & Marazita, M. L., 1 Jul 2016, In : Human Molecular Genetics. 25, 13, p. 2862-2872 11 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase

Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
130 Downloads (Pure)

A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features

Fetit, A., Doney, A., Hogg, S., Wang, R., MacGillivray, T., Wardlaw, J. M., Doubal, F. N., McKay, G. J., McKenna, S. & Trucco, E., 5 Mar 2019, In : Scientific Reports. 9, 1, p. 1-10 10 p., 3591.

Research output: Contribution to journalArticle

Open Access
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109 Downloads (Pure)

A multiscale mathematical model of tumour invasive growth

Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In : Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
142 Downloads (Pure)

A multispecialty study of determining the possibility of pregnancy and the documentation of pregnancy status in surgical patients: a cause for concern?

Ibrahim, I., Ibrahim, B., Yong, G. L., Coats, M., Vujovic, Z. & Wilson, M. S. J., 1 Nov 2018, In : Scottish Medical Journal. 63, 4, p. 108-112 5 p.

Research output: Contribution to journalArticle

A mutant O-GlcNAcase enriches Drosophila developmental regulators

Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In : Nature Chemical Biology. 13, 8, p. 882-887 8 p.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
156 Downloads (Pure)

Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease

Pickett, E. K., Herrmann, A. G., McQueen, J., Abt, K., Dando, O., Tulloch, J., Jain, P., Dunnett, S., Sohrabi, S., Fjeldstad, M. P., Calkin, W., Murison, L., Jackson, R. J., Tzioras, M., Stevenson, A., d'Orange, M., Hooley, M., Davies, C., Colom-Cadena, M., Anton-Fernandez, A. & 10 others, King, D., Oren, I., Rose, J., McKenzie, C. A., Allison, E., Smith, C., Hardt, O., Henstridge, C. M., Hardingham, G. E. & Spires-Jones, T. L., 10 Dec 2019, In : Cell Reports. 29, 11, p. 3592-3604.e5

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
37 Downloads (Pure)

Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity

Cuthbertson, D. J., Babraj, J., Leese, G. & Siervo, M., Dec 2017, In : Clinical Nutrition. 36, 6, p. 1716-1719 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

An acute transfusion reaction

Webb, C., Norris, A. & Hands, K., 1 Feb 2018, In : Clinical Medicine - Journal of the Royal College of Physicians of London. 18, 1, p. 95-97 3 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Anaesthesia for laryngo-tracheal surgery, including tubeless field techniques

Pearson, K. L. & McGuire, B. E., 1 Jul 2017, In : BJA Education. 17, 7, p. 242-248 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

An Affinity-directed PROtein Missile (AdPROM) system for targeted proteolysis

Fulcher, L., Macartney, T., Bozatzi, P., Hornberger, A., Rojas-Fernandez, A. & Sapkota, G., 26 Oct 2016, In : Open Biology. 6, 10, p. 1-9 9 p., 160255.

Research output: Contribution to journalArticle

Open Access
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19 Citations (Scopus)
138 Downloads (Pure)

An African Legal Philosophy of Disability Justice: Between Discovery and Recognition

Onazi, O., 30 Jun 2016, In : ISRF Bulletin. Discovery & Recognition, X, p. 33-38 6 p.

Research output: Contribution to journalArticle

Open Access
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736 Downloads (Pure)

An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel

Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In : NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
139 Downloads (Pure)

Análisis de la formación y el ámbito de práctica de los médicos de atención primaria en Inglaterra, Alemania y España

Translated title of the contribution: Exploring the training and scope of practice of GPs in England, Germany and SpainGlonti, K., Struckmann, V., Alconada, A., Pettigrew, L. M., Hernandez-Santiago, V., Minue, S., Risso-Gill, I., McKee, M. & Legido-Quigley, H., Mar 2019, In : Gaceta Sanitaria. 33, 2, p. 148-155 8 p.

Research output: Contribution to journalArticle

Open Access
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An Alternative Genealogy for Global Capitalism: The Rhine Becomes an Inland Sea 1792-1815

Livesey, J., 1 Nov 2019, In : Critical Historical Studies. 6, 2, p. 223-245 23 p.

Research output: Contribution to journalArticle

Analysing trajectories of a longitudinal exposure: a causal perspective on common methods in lifecourse research

Gadd, S. C., Tennant, P. W. G., Heppenstall, A. J., Boehnke, J. & Gilthorpe, M. S., 4 Dec 2019, In : PLoS ONE. 14, 12, p. 1-12 12 p., e0225217.

Research output: Contribution to journalArticle

Open Access
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Analysis of consolidation with constant rate of displacement

Muir Wood, D., May 2016, In : Canadian Geotechnical Journal. 53, 5, p. 740-752 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access
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1 Citation (Scopus)
138 Downloads (Pure)

Analysis of DrkA kinase's role in STATa activation

Saga, Y., Iwade, Y., Araki, T., Ishikawa, M. & Kawata, T., 17 Jun 2019, In : Genes to Cells. 24, 6, p. 422-435 14 p.

Research output: Contribution to journalArticle

Open Access
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Analysis of hand pressure in different crutch lengths and upper-limb movements during crutched walking

Sherif, S., Hasan, S., Arnold, G., Abboud, R. & Wang, W., May 2016, In : International Journal of Industrial Ergonomics. 53, p. 59-66 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Analysis of in-situ soil moisture data and validation of SMOS soil moisture products at selected agricultural sites over a tropical region

Kang, C. S., Kanniah, K. D., Kerr, Y. H. & Cracknell, A. P., 17 Aug 2016, In : International Journal of Remote Sensing. 37, 16, p. 3636-3654 19 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Analysis of novel missense ATR mutations reveals new splicing defects underlying Seckel Syndrome

Llorens-Agost, M., Luessing, J., van Beneden, A., Eykelenboom, J., O'Reilly, D., Bicknell, L. S., Reynolds, J. J., van Koegelenberg, M., Hurles, M. E., Brady, A. F., Jackson, A. P., Stewart, G. S. & Lowndes, N. F., Dec 2018, In : Human Mutation. 39, 12, p. 1847-1853 7 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
93 Downloads (Pure)

Analysis of physical pore space characteristics of two pyrolytic biochars and potential as microhabitat

Schnee, L. S., Knauth, S., Hapca, S., Otten, W. & Eickhorst, T., Nov 2016, In : Plant and Soil. 408, 1, p. 357-368 12 p.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
254 Downloads (Pure)

Analysis of plant root-induced preferential flow and pore water pressure variation by a dual-permeability model

Shao, W., Ni, J., Leung, A. K., Su, Y. & Ng, C. W. W., 2017, In : Canadian Geotechnical Journal. 54, 11, p. 1537-1552 16 p.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)
185 Downloads (Pure)

Analysis of root growth from a phenotyping data set using a density-based model

Kalogiros, D. I., Adu, M. O., White, P. J., Broadley, M. R., Draye, X., Ptashnyk, M., Bengough, A. G. & Dupuy, L. X., Feb 2016, In : Journal of Experimental Botany. 67, 4, p. 1045-1058 14 p.

Research output: Contribution to journalArticle

Open Access
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16 Citations (Scopus)
133 Downloads (Pure)