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2014

Art’s asymptotic leadership: Arts leadership, education and the loss of autonomy

Baldacchino, J., 1 Sep 2014, In : Visual Inquiry. 3, 3, p. 291-305 15 p., 3.

Research output: Contribution to journalArticle

Open Access
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241 Downloads (Pure)
2016

Synthesis of isomeric phosphoubiquitin chains reveals that phosphorylation controls deubiquitinase activity and specificity

Huguenin-Dezot, N., De Cesare, V., Peltier, J., Knebel, A., Kristariyanto, Y. A., Rogerson, D. T., Kulathu, Y., Trost, M. & Chin, J. W., 26 Jul 2016, In : Cell Reports. 16, 4, p. 1180-1193 14 p.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
135 Downloads (Pure)
2007

Natural phosphoglycans containing glycosyl phosphate units: structural diversity and chemical synthesis

Nikolaev, A. V., Botvinko, I. V. & Ross, A. J., 26 Feb 2007, In : Carbohydrate Research. 342, 3-4, p. 297-344 48 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
2014

Lack of correlation of stem cell markers in breast cancer stem cells

Liu, Y., Nenutil, R., Appleyard, M. V., Murray, K., Boylan, M., Thompson, A. M. & Coates, P. J., 15 Apr 2014, In : British Journal of Cancer. 110, 8, p. 2063-2071 9 p.

Research output: Contribution to journalArticle

Open Access
File
55 Citations (Scopus)
131 Downloads (Pure)
718 Citations (Scopus)

NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis

South, A. P., Purdie, K. J., Watt, S. A., Haldenby, S., den Breems, N., Dimon, M., Arron, S. T., Kluk, M. J., Aster, J. C., McHugh, A., Xue, D. J., Dayal, J. H. S., Robinson, K. S., Rizvi, S. M. H., Proby, C. M., Harwood, C. A. & Leigh, I. M., Oct 2014, In : Journal of Investigative Dermatology. 134, 10, p. 2630-2638 9 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)
2007

Simvastatin does not exhibit therapeutic anti-inflammatory effects in asthma

Menzies, D., Nair, A., Meldrum, K. T., Fleming, D., Barnes, M. & Lipworth, B. J., 2007, In : Journal of Allergy and Clinical Immunology. 119, 2, p. 328-335 8 p.

Research output: Contribution to journalArticle

108 Citations (Scopus)
2008

Screening uptake in a well-established diabetic retinopathy screening program: the role of geographical access and deprivation

Leese, G. P., Boyle, P., Feng, Z., Emslie-Smith, A. & Ellis, J. D., Nov 2008, In : Diabetes Care. 31, 11, p. 2131-2135 5 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)
2009

TOPALi v2: a rich graphical interface for evolutionary analyses of multiple alignments on HPC clusters and multi-core desktops

Milne, I., Lindner, D., Bayer, M., Husmeier, D., McGuire, G., Marshall, D. F. & Wright, F., 2009, In : Bioinformatics. 25, 1, p. 126-127 2 p.

Research output: Contribution to journalArticle

447 Citations (Scopus)
2014

The role of ligand efficiency metrics in drug discovery

Hopkins, A. L., Keserü, G. M., Leeson, P. D., Rees, D. C. & Reynolds, C. H., 2014, In : Nature Reviews Drug Discovery. 13, 2, p. 105-121 17 p.

Research output: Contribution to journalArticle

455 Citations (Scopus)
2008

The epigenetics of rRNA genes: from molecular to chromosome biology

McStay, B. & Grummt, I., 2008, In : Annual Review of Cell and Developmental Biology. 24, p. 131-157 27 p.

Research output: Contribution to journalArticle

336 Citations (Scopus)
2007

TCF7L2 in the Go-DARTS study: evidence for a gene dose effect on both diabetes susceptibility and control of glucose levels

Kimber, C. H., Doney, A. S. F., Pearson, E. R., McCarthy, M. I., Hattersley, A. T., Leese, G. P., Morris, A. D. & Palmer, C. N. A., Jun 2007, In : Diabetologia. 50, 6, p. 1186-1191 6 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

The multifunctional nucleolus

Boisvert, F-M., van Koningsbruggen, S., Navascués, J. & Lamond, A. I., 2007, In : Nature Reviews Molecular Cell Biology. 8, 7, p. 574-585 12 p.

Research output: Contribution to journalArticle

886 Citations (Scopus)

PTEN is destabilized by phosphorylation on Thr366

Maccario, H., Perera, N. M., Davidson, L., Downes, C. P. & Leslie, N. R., 1 Aug 2007, In : Biochemical Journal. 405, 3, p. 439-444 6 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)
2014

Biosorption: current perspectives on concept, definition and application

Fomina, M. & Gadd, G. M., May 2014, In : Bioresource Technology. 160, p. 3-14 12 p.

Research output: Contribution to journalArticle

392 Citations (Scopus)

Atopic dermatitis and disease severity are the main risk factors for food sensitization in exclusively breastfed infants

Flohr, C., Perkin, M., Logan, K., Marrs, T., Radulovic, S., Campbell, L. E., Maccallum, S. F., McLean, W. H. I. & Lack, G., Feb 2014, In : Journal of Investigative Dermatology. 134, 2, p. 345-350 6 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Guidance on posterior resin composites: Academy of Operative Dentistry - European Section

Lynch, C. D., Opdam, N. J., Hickel, R., Brunton, P. A., Gurgan, S., Kakaboura, A., Shearer, A. C., Vanherle, G. & Wilson, N. H. F., Apr 2014, In : Journal of Dentistry. 42, 4, p. 377-383 7 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)
2007

Legume evolution: where do nodules and mycorrhizas fit in?

Sprent, J. I. & James, E. K., Jun 2007, In : Plant Physiology. 144, 2, p. 575-581 7 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)
2008

Novel substrates and functions for the ubiquitin-like molecule NEDD8

Xirodimas, D. P., Oct 2008, In : Biochemical Society Transactions. 36, 5, p. 802-806 5 p.

Research output: Contribution to journalArticle

122 Citations (Scopus)
2013

The concise guide to PHARMACOLOGY 2013/14: Overview

Alexander, S. P. H., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., McGrath, J. C., Catterall, W. A., Spedding, M., Peters, J. A. & Harmar, A. J., 1 Dec 2013, In : British Journal of Pharmacology. 170, 8, p. 1449-1458 10 p.

Research output: Contribution to journalArticle

132 Citations (Scopus)
2014

Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability

Tatton-Brown, K., Seal, S., Ruark, E., Harmer, J., Ramsay, E., del Vecchio Duarte, S., Zachariou, A., Hanks, S., O'Brien, E., Aksglaede, L., Baralle, D., Dabir, T., Gener, B., Goudie, D., Homfray, T., Kumar, A., Pilz, D. T., Selicorni, A., Temple, I. K., Van Maldergem, L. & 4 others, Yachelevich, N., Childhood Overgrowth Consortium, van Montfort, R. & Rahman, N., Apr 2014, In : Nature Genetics. 46, 4, p. 385-388 4 p.

Research output: Contribution to journalArticle

127 Citations (Scopus)
2007

Evolving ideas of legume evolution and diversity: a taxonomic perspective on the occurrence of nodulation

Sprent, J. I., 2007, In : New Phytologist. 174, 1, p. 11-25 15 p.

Research output: Contribution to journalArticle

261 Citations (Scopus)
2008

The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease

Belch, J., MacCuish, A., Campbell, I., Cobbe, S., Taylor, R., Prescott, R., Lee, R., Bancroft, J., MacEwan, S., Shepherd, J., Macfarlane, P., Morris, A., Jung, R., Kelly, C., Connacher, A., Peden, N., Jamieson, A., Matthews, D., Leese, G., McKnight, J. & 7 others, O'Brien, I., Semple, C., Petrie, J., Gordon, D., Pringle, S., MacWalter, R. & Diabet Registry Grp, Prevent Progression Arterial Dis &, Royal Coll Phys Edinburgh, 1 Nov 2008, In : BMJ. 337, 7677, p. 1-10 10 p., a1840.

Research output: Contribution to journalArticle

456 Citations (Scopus)
2010

Spironolactone use and renal toxicity: population based longitudinal analysis

Wei, L., Struthers, A. D., Fahey, T., Watson, A. D. & MacDonald, T. M., 18 May 2010, In : BMJ. 340, p. - 5 p., c1768.

Research output: Contribution to journalArticle

70 Citations (Scopus)
2011

Effect of Hypoxia-Inducible Factor-1 alpha Gene Therapy on Walking Performance in Patients With Intermittent Claudication

Creager, M. A., Olin, J. W., Belch, J. J. F., Moneta, G. L., Henry, T. D., Rajagopalan, S., Annex, B. H. & Hiatt, W. R., 18 Oct 2011, In : Circulation. 124, 16, p. 1765-U148 11 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

A general and efficient approach for the construction of RNA oligonucleotides containing a 5'-phosphorothiolate linkage

Li, N-S., Frederiksen, J. K., Koo, S. C., Lu, J., Wilson, T. J., Lilley, D. M. J. & Piccirilli, J. A., Mar 2011, In : Nucleic Acids Research. 39, 5, p. - 16 p., e31.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2010

Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme

Wilson, T. J., Li, N-S., Lu, J., Frederiksen, J. K., Piccirilli, J. A. & Lilley, D. M. J., 29 Jun 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 26, p. 11751-11756 6 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)
2008

Development of a treatment algorithm for actinic keratoses: a European Consensus

Stockfleth, E., Ferrandiz, C., Grob, J. J., Leigh, I., Pehamberger, H., Kerl, H. & European Skin Acad, 2008, In : European Journal of Dermatology. 18, 6, p. 651-659 9 p.

Research output: Contribution to journalArticle

161 Citations (Scopus)
2011

Tracking of obesity-related behaviours from childhood to adulthood: A systematic review

Craigie, A. M., Lake, A. A., Kelly, S. A., Adamson, A. J. & Mathers, J. C., Nov 2011, In : Maturitas. 70, 3, p. 266-284 19 p.

Research output: Contribution to journalReview article

411 Citations (Scopus)

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

Artigas, M. S., Loth, D. W., Wain, L. V., Gharib, S. A., Obeidat, M., Tang, W., Zhai, G., Zhao, J. H., Smith, A. V., Huffman, J. E., Albrecht, E., Jackson, C. M., Evans, D. M., Cadby, G., Fornage, M., Manichaikul, A., Lopez, L. M., Johnson, T., Aldrich, M. C., Aspelund, T. & 31 others, Barroso, I., Campbell, H., Cassano, P. A., Couper, D. J., Eiriksdottir, G., Franceschini, N., Garcia, M., Gieger, C., Gislason, G. K., Grkovic, I., Hammond, C. J., Hancock, D. B., Harris, T. B., Ramasamy, A., Heckbert, S. R., Heliovaara, M., Homuth, G., Hysi, P. G., James, A. L., Jankovic, S., Joubert, B. R., Karrasch, S., Klopp, N., Koch, B., Kritchevsky, S. B., Launer, L. J., Liu, Y., Loehr, L. R., Morris, A. D., Smith, G. D. & GIANT Consortium, Int Lung Canc Consortium, Nov 2011, In : Nature Genetics. 43, 11, p. 1082-U70 11 p.

Research output: Contribution to journalArticle

264 Citations (Scopus)
2010

Physicochemical properties affecting cellular uptake of carbon nanotubes

Raffa, V., Ciofani, G., Vittorio, O., Riggio, C. & Cuschieri, A., Jan 2010, In : Nanomedicine. 5, 1, p. 89-97 9 p.

Research output: Contribution to journalReview article

128 Citations (Scopus)
2009

Ergonomic assessment of optimum operating table height for hand-assisted laparoscopic surgery

Manasnayakorn, S., Cuschieri, A. & Hanna, G. B., Apr 2009, In : Surgical Endoscopy. 23, 4, p. 783-789 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2008

Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes

Rafiq, S., Melzer, D., Weedon, M. N., Lango, H., Saxena, R., Scott, L. J., Palmer, C. N. A., Morris, A. D., McCarthy, M. I., Ferrucci, L., Hattersley, A. T., Zeggini, E., Frayling, T. M. & DIAGRAM Consortium, Dec 2008, In : Diabetologia. 51, 12, p. 2205-2213 9 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Vitamin D improves endothelial function in patients with Type 2 diabetes mellitus and low vitamin D levels

Sugden, J. A., Davies, J. I., Witham, M. D., Morris, A. D. & Struthers, A. D., Mar 2008, In : Diabetic Medicine. 25, 3, p. 320-325 6 p.

Research output: Contribution to journalArticle

400 Citations (Scopus)
2007

Mineralocorticoid receptor antagonists

Parthasarathy, H. K. & MacDonald, T. M., Mar 2007, In : Current Hypertension Reports. 9, 1, p. 45-52 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2010
23 Citations (Scopus)

Development of the spatial representation system in the rat

Langston, R. F., Ainge, J. A., Couey, J. J., Canto, C. B., Bjerknes, T. L., Witter, M. P., Moser, E. I. & Moser, M-B., 18 Jun 2010, In : Science. 328, 5985, p. 1576-1580 5 p.

Research output: Contribution to journalArticle

329 Citations (Scopus)
2009

New users of metformin are at low risk of incident cancer a cohort study among people with type 2 diabetes

Libby, G., Donnelly, L. A., Donnan, P. T., Alessi, D. R., Morris, A. D. & Evans, J. M. M., Sep 2009, In : Diabetes Care. 32, 9, p. 1620-1625 6 p.

Research output: Contribution to journalArticle

742 Citations (Scopus)
2012

AMPK: a nutrient and energy sensor that maintains energy homeostasis

Hardie, D. G., Ross, F. A. & Hawley, S. A., 1 Apr 2012, In : Nature Reviews Molecular Cell Biology. 13, 4, p. 251-262 12 p.

Research output: Contribution to journalReview article

Open Access
File
1943 Citations (Scopus)
176 Downloads (Pure)
2009

Novel operative treatment options

Ricketts, D. N. J. & Pitts, N. B., 2009, Monographs in Oral Science. Vol. 21. p. 174-187 14 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

17 Citations (Scopus)
2011
149 Citations (Scopus)
2012

Bacteria, Colonic Fermentation, and Gastrointestinal Health

Macfarlane, G. T. & Macfarlane, S., 2012, In : Journal of AOAC International. 95, 1, p. 50-60 11 p.

Research output: Contribution to journalArticle

351 Citations (Scopus)

Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity

Calabrese, V., Cornelius, C., Dinkova-Kostova, A. T., Iavicoli, I., Di Paola, R., Koverech, A., Cuzzocrea, S., Rizzarelli, E. & Calabrese, E. J., May 2012, In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1822, 5, p. 753-783 31 p.

Research output: Contribution to journalReview article

244 Citations (Scopus)
2008

Germline survival and apoptosis

Gartner, A., Boag, P. R. & Blackwell, T. K., 1 Jan 2008, In : WormBook. p. 1-20 20 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)
2012

Impaired associative taste learning and abnormal brain activation in kinase-defective eEF2K mice

Gildish, I., Manor, D., David, O., Sharma, V., Williams, D., Agarwala, U., Wang, X., Kenney, J. W., Proud, C. G. & Rosenblum, K., Mar 2012, In : Learning and Memory. 19, 3, p. 116-125 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2011

Quantifying the role of angiogenesis in malignant progression of gliomas: In Silico modeling integrates imaging and histology

Swanson, K. R., Rockne, R. C., Alvord Jr., E. C., Claridge, J., Chaplain, M. A. & Anderson, A. R. A., 2011, In : Cancer Research. 71, 24, p. 7366-7375 10 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)
2012

Donepezil and Memantine for moderate-to-severe Alzheimer's Disease

Howard, R., McShane, R., Lindesay, J., Ritchie, C., Baldwin, A., Barber, R., Burns, A., Dening, T., Findlay, D., Holmes, C., Hughes, A., Jacoby, R., Jones, R., Jones, R., McKeith, I., Macharouthu, A., O'Brien, J., Passmore, P., Sheehan, B., Juszczak, E. & 13 others, Katona, C., Hills, R., Knapp, M., Ballard, C., Brown, R., Banerjee, S., Onions, C., Griffin, M., Adams, J., Gray, R., Johnson, T., Bentham, P. & Phillips, P., 2012, In : New England Journal of Medicine. 366, 10, p. 893-903 11 p.

Research output: Contribution to journalArticle

Open Access
388 Citations (Scopus)

The Use of Pedometers in Stroke Survivors: Are They Feasible and How Well Do They Defect Steps?

Carroll, S. L., Greig, C. A., Lewis, S. J., McMurdo, M. E., Sniehotta, F. F., Johnston, M., Johnston, D. W., Scopes, J. & Mead, G. E., Mar 2012, In : Archives of Physical Medicine and Rehabilitation. 93, 3, p. 466-470 5 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2010

Elevated heart rate and cardiovascular outcomes in patients with coronary artery disease: clinical evidence and pathophysiological mechanisms

Lang, C. C., Gupta, S., Kalra, P., Keavney, B., Menown, I., Morley, C. & Padmanabhan, S., 2010, In : Atherosclerosis. 212, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)