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Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

Emmerich, C. H., Ordureau, A., Strickson, S., Arthur, J. S. C., Pedrioli, P. G. A., Komander, D. & Cohen, P., 17 Sep 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 38, p. 15247-15252 6 p.

Research output: Contribution to journalArticle

Open Access
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220 Citations (Scopus)
142 Downloads (Pure)

Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation

Canedo, C. S., Demeulder, B., Ginion, A., Bayascas, J. R., Balligand, J-L., Alessi, D. R., Vanoverschelde, J-L., Beauloye, C., Hue, L. & Bertrand, L., Apr 2010, In : American Journal of Physiology, Endocrinology and Metabolism. 298, 4, p. E761-E769 9 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Activation of the cryptic DNA binding function of mutant forms of p53

Hupp, T. R., Meek, D. W., Midgley, C. A. & Lane, D. P., 11 Jul 1993, In : Nucleic Acids Research. 21, 14, p. 3167-3174 8 p.

Research output: Contribution to journalArticle

180 Citations (Scopus)

Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains

Mallery, D. L., Vandenberg, C. J. & Hiom, K., 16 Dec 2002, In : EMBO Journal. 21, 24, p. 6755-6762 8 p.

Research output: Contribution to journalArticle

214 Citations (Scopus)

Activation of the MAP kinase homologue RK requires the phosphorylation of Thr-180 and Tyr-182 and both residues are phosphorylated in chemically stressed KB cells

Doza, Y. N., Cuenda, A., Thomas, G. M., Cohen, P. & Nebreda, A. R., 8 May 1995, In : FEBS Letters. 364, 2, p. 223-228 6 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Activation of the MAP kinase pathway by the protein kinase raf

Howe, L. R., Leevers, S. J., Gómez, N., Nakielny, S., Cohen, P. & Marshall, C. J., 16 Oct 1992, In : Cell. 71, 2, p. 335-342 8 p.

Research output: Contribution to journalArticle

613 Citations (Scopus)

Activation of the MAP kinase pathway requires p21ras and p74raf-1

Marshall, C. J., Ashworth, A., Howe, L. R., Leevers, S. J., Paterson, H. F., Thorneycroft, S. G., Gomez, N., Nakielny, S., Traverse, S. & Cohen, P., 1 Jan 1993, In : International Journal of Cancer. 53, 1, p. 171-172 2 p.

Research output: Contribution to journalArticle

Activation of the neutrophil NADPH oxidase is inhibited by SB 203580, a specific inhibitor of SAPK2/p38

Lal, A. S., Clifton, A. D., Rouse, J., Segal, A. W. & Cohen, P., 7 Jun 1999, In : Biochemical and Biophysical Research Communications. 259, 2, p. 465-470 6 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); Comparison of its substrate specificity with that of other SAP kinases

Goedert, M., Cuenda, A., Craxton, M., Jakes, R. & Cohen, P., 16 Jun 1997, In : EMBO Journal. 16, 12, p. 3563-3571 9 p.

Research output: Contribution to journalArticle

Open Access
344 Citations (Scopus)

Activation of the NRF2 Signaling Pathway by Copper-Mediated Redox Cycling of Para- and Ortho-Hydroquinones

Wang, X. J., Hayes, J. D., Higgins, L. G., Wolf, C. R. & Dinkova-Kostova, A. T., 29 Jan 2010, In : Chemistry & Biology. 17, 1, p. 75-85 11 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Activation of the protease from human adenovirus type 2 is accompanied by a conformational change that is dependent on cysteine-104

Jones, S. J., Iqbal, M., Grierson, A. W. & Kemp, G., Aug 1996, In : Journal of General Virology. 77, 8, p. 1821-1824

Research output: Contribution to journalArticle

9 Citations (Scopus)
48 Citations (Scopus)

Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process

Castaneda-Bueno, M., Graciela Cervantes-Perez, L., Vazquez, N., Uribe, N., Kantesaria, S., Morla, L., Bobadilla, N. A., Doucet, A., Alessi, D. R. & Gamba, G., 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 20, p. 7929-7934 6 p.

Research output: Contribution to journalArticle

157 Citations (Scopus)

Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

Richardson, C., Rafiqi, F. H., Karlsson, H. K. R., Moleleki, N., Vandewalle, A., Campbell, D. G., Morrice, N. A. & Alessi, D. R., 1 Mar 2008, In : Journal of Cell Science. 121, 5, p. 675-684 10 p.

Research output: Contribution to journalArticle

247 Citations (Scopus)

Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD

Baas, A. F., Boudeau, J., Sapkota, G. P., Smit, L., Medema, R., Morrice, N. A., Alessi, D. R. & Clevers, H. C., 2003, In : EMBO Journal. 22, 12, p. 3062-3072 11 p.

Research output: Contribution to journalArticle

269 Citations (Scopus)
Open Access
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1 Citation (Scopus)
28 Downloads (Pure)

Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R., 1 Nov 2015, In : Cancer Research. 75, 21, p. 4573-4581 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
Open Access
209 Citations (Scopus)

Activators of the Epstein-Barr virus lytic program concomitantly induce apoptosis, but lytic gene expression protects from cell death

Inman, G. J., Binné, U. K., Parker, G. A., Farrell, P. J. & Allday, M. J., 2001, In : Journal of Virology. 75, 5, p. 2400-2410 11 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Active defence responses associated with non-host resistance of Arabidopsis thaliana to the oomycete pathogen Phytophthora infestans

Huitema, E., Vleeshouwers, V. G. A. A., Francis, D. M. & Kamoun, S., Nov 2003, In : Molecular Plant Pathology. 4, 6, p. 487-500 14 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Active-learning methods to improve student performance and scientific interest in a large introductory oceanography course

Yuretich, R. F., Khan, S., Leckie, R. M. & Clement, J. J., Mar 2001, In : Journal of Geoscience Education. 49, 2, p. 111-119 9 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Active membranes: 3D printing of elastic fibre patterns on pre-stretched textiles

Agkathidis, A., Berdos, Y. & Brown, A., 1 Mar 2019, In : International Journal of Architectural Computing. 17, 1, p. 74-87 14 p.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
18 Downloads (Pure)

Active momentum trading versus passive '1/N naive diversification'

Banerjee, A. N. & Hung, C-H. D., May 2013, In : Quantitative Finance. 13, 5, p. 655-663 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Active queue management algorithms in DiffServ networks

Liu, W., Cheng, W. Q., He, J. H., Le, C. H., Chou, C. T. & Yang, Z. K., 1 Jun 2005, In : Ruan Jian Xue Bao/Journal of Software. 16, 6, p. 1120-1130 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Active repression of antiapoptotic gene expression by RelA(p65) NF-kB

Campbell, K. J., Rocha, S. & Perkins, N. D., Mar 2004, In : Molecular Cell. 13, 6, p. 853-865 13 p.

Research output: Contribution to journalArticle

335 Citations (Scopus)

Active restoration accelerates the carbon recovery of human modified-tropical forests

Philipson, C., Cutler, M., Brodrick, P. G., Asner, G. P., Boyd, D. S., Costa, P. M., Fiddes, J., Foody, G. M., van der Heijden, G. M. F., Ledo, A., Lincoln, P. R., Margrove, J. A., Martin, R. E., Milne, S., Pinard, M. A., Reynolds, G., Snoep, M., Tangki, H., Wai, Y. S., Wheeler, C. E. & 1 others, Burslem, D. F. R. P., 14 Aug 2020, In : Science. 369, 6505, p. 838-841 4 p.

Research output: Contribution to journalArticle

Open Access
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113 Downloads (Pure)

Active site residues in m-calpain: identification by site-directed mutagenesis

Arthur, J. S. C., Gauthier, S. & Elce, J. S., 24 Jul 1995, In : FEBS Letters. 368, 3, p. 397-400 4 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Active-site topologies of human CYP2D6 and its aspartate-301 → glutamate, asparagine, and glycine mutants

Mackman, R., Tschirret-Guth, R. A., Smith, G., Hayhurst, G. P., Ellis, S. W., Lennard, M. S., Tucker, G. T., Wolf, C. R. & Ortiz de Montellano, P. R., 1996, In : Archives of Biochemistry and Biophysics. 331, 1, p. 134-140 7 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Active stabilisation and timing jitter characterisation of sub-500fs pulse passively modelocked VECSEL

Quarterman, A. H., Wilcox, K. G., Elsmere, S. P., Mihoubi, Z. & Tropper, A. C., 16 Sep 2008, In : Electronics Letters. 44, 19, p. 1135-1137 3 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Active swarms on a sphere

Sknepnek, R. & Henkes, S., 17 Feb 2015, In : Physical Review E: Statistical, Nonlinear, and Soft Matter Physics. 91, 2, 5 p., 022306.

Research output: Contribution to journalArticle

Open Access
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35 Citations (Scopus)
257 Downloads (Pure)

Active transport of the Ubiquitin Ligase MID1 along the microtubules Is regulated by Protein Phosphatase 2A

Aranda-Orgilles, B., Aigner, J., Kunath, M., Lurz, R., Schneider, R. & Schweiger, S., 24 Oct 2008, In : PLoS ONE. 3, 10, p. - 8 p., e3507.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Active Vertex Model for Cell-Resolution Description of Epithelial Tissue Mechanics

Barton, D. L., Henkes, S., Weijer, C. J. & Sknepnek, R., 30 Jun 2017, In : PLoS Computational Biology. 13, 6, 34 p., e1005569.

Research output: Contribution to journalArticle

Open Access
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60 Citations (Scopus)
233 Downloads (Pure)

Active water transport in unicellular algae: where, why, and how

Raven, J. A. & Doblin, M. A., 22 Dec 2014, In : Journal of Experimental Botany. 65, 22, p. 6279-6292 14 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Active β-Amyloid Immunization Restores Spatial Learning in PDAPP Mice Displaying Very Low Levels of β-Amyloid

Chen, G., Chen, K. S., Kobayashi, D., Barbour, R., Motter, R., Games, D., Martin, S. J. & Morris, R. G. M., 7 Mar 2007, In : Journal of Neuroscience. 27, 10, p. 2654-2662 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Activism, separation of powers and development

Mishra, A. & Anant, T. C. A., Dec 2006, In : Journal of Development Economics. 81, 2

Research output: Contribution to journalArticle

2 Citations (Scopus)

Activities related to the occurrence of traumatic dental injuries in 15- to 18-year-olds

Huang, B., Marcenes, W., Croucher, R. & Hector, M., 1 Feb 2009, In : Dental Traumatology. 25, 1, p. 64-68 5 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity

Pao, K-C., Wood, N. T., Knebel, A., Rafie, K., Stanley, M., Mabbitt, P. D., Sundaramoorthy, R., Hofmann, K., van Aalten, D. M. F. & Virdee, S., 11 Apr 2018, In : Nature. 556, 7701, p. 381-385 5 p.

Research output: Contribution to journalArticle

Open Access
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39 Citations (Scopus)
399 Downloads (Pure)

Activity of any class IA PI3K isoform can sustain cell proliferation and survival

Foukas, L. C., Berenjeno, I. M., Gray, A., Khwaja, A. & Vanhaesebroeck, B., 22 Jun 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 25, p. 11381-11386 6 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)
250 Citations (Scopus)
Open Access
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3 Citations (Scopus)
155 Downloads (Pure)

'Actual Pinching and Suffering’: Estate Responses to Poverty in Sutherland, 1845-86

Tindley, A., Oct 2011, In : Scottish Historical Review. 90, 2, p. 236-256 20 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Actuarial life-table analysis of lower impacted wisdom teeth in general dental practice

Fernandes, M. J., Ogden, G. R., Pitts, N. B., Ogston, S. A. & Ruta, D. A., Feb 2010, In : Community Dentistry and Oral Epidemiology. 38, 1, p. 58-67 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

A cuckoo covid coincidence?

Chalmers, J. D. & Lonergan, M., 9 Sep 2020, In : European Respiratory Journal. 4 p.

Research output: Contribution to journalArticle

Open Access
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14 Downloads (Pure)

A cultivation-independent approach for the genetic and cyanotoxin characterization of colonial cyanobacteria

Lara, Y., Lambion, A., Menzel, D., Codd, G. A. & Wilmotte, A., 2013, In : Aquatic Microbial Ecology. 69, 2, p. 135-143 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A current assessment of photosystem II structure

Nicholson, W. V., Ford, R. C. & Holzenburg, A., Apr 1996, In : Bioscience Reports. 16, 2, p. 159-187 29 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Acute Achilles tendon rupture: Do cast boots produce adequate equinus when used for functional rehabilitation?

MacDonald, D. R. W., Neilly, D., Littlechild, J., Harrold, F. & Roberts, S. C., Dec 2018, In : Foot. 37, p. 1-4 4 p.

Research output: Contribution to journalArticle

Acute and chronic neuropathic pain in the hospital setting: Use of screening tools

Sadler, A., Wilson, J. & Colvin, L., 1 Jun 2013, In : Clinical Journal of Pain. 29, 6, p. 507-511 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
68 Citations (Scopus)

Acute effects of atrial natriuretic peptide on left ventricular diastolic function: A pulsed wave Doppler study in man

Clarkson, P. B. M., Wheeldon, N. M., Macleod, C., Coutie, W. & MacDonald, T. M., 1 Nov 1995, In : European Heart Journal. 16, 11, p. 1710-1715 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Acute effects of captopril on the renal actions of furosemide in patients with chronic heart failure

McLay, J. S., McMurray, J. J., Bridges, A. B., Fraser, C. G. & Struthers, A. D., 1 Oct 1993, In : American Heart Journal. 126, 4, p. 879-86 8 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)