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  • James Chalmers
2019

A point of care neutrophil elastase activity assay identifies bronchiectasis severity, airway infection and risk of exacerbation

Shoemark, A., Cant, E., Carreto, L., Smith, A., Oriano, M., Keir, H. R., Perea, L., Canto, E., Terranova, L., Vidal, S., Moffitt, K., Aliberti, S., Sibila, O. & Chalmers, J. D., 1 Jun 2019, In : European Respiratory Journal. 53, 6, 1900303.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
12 Downloads (Pure)
2015

Etiology of non-cystic fibrosis bronchiectasis in adults and its correlation to disease severity

Lonni, S., Chalmers, J. D., Goeminne, P. C., McDonnell, M. J., Dimakou, K., De Soyza, A., Polverino, E., Van De Kerkhove, C., Rutherford, R., Davison, J., Rosales, E., Pesci, A., Restrepo, M. I., Torres, A. & Aliberti, S., Dec 2015, In : Annals of the American Thoracic Society. 12, 12, p. 1764-1770 7 p.

Research output: Contribution to journalArticle

122 Citations (Scopus)
2020

Happy Birthday Bronchiectasis: 200 Years of Targeting Mucus

Chalmers, J. D. & Sibila, O., 15 Mar 2020, In : American Journal of Respiratory and Critical Care Medicine. 201, 6, p. 639-640 2 p.

Research output: Contribution to journalEditorial

Open Access
File
20 Downloads (Pure)

Utility of routine screening for alpha-1 antitrypsin deficiency in patients with bronchiectasis

Carreto, L., Morrison, M., Donovan, J., Finch, S., Tan, G. L., Fardon, T., Wilson, R., Furrie, E., Loebinger, M. & Chalmers, J. D., 17 Apr 2020, In : Thorax. 2 p., 2019-214195.

Research output: Contribution to journalArticle

Open Access
File
15 Downloads (Pure)
2017

Management of chronic airway diseases: What can we learn from real-life data?

Chalmers, J. D., 17 Mar 2017, In : COPD. 14, Suppl. 1, p. S1-S2 2 p.

Research output: Contribution to journalArticle

Open Access
File
195 Downloads (Pure)
2020

Changes in respiratory symptoms during 48 weeks treatment with ARD-3150 (inhaled liposomal ciprofloxacin) in bronchiectasis: results from the ORBIT-3 and -4 studies

Chalmers, J. D., Cipolla, D., Thompson, B., Davis, A. M., O'Donnell, A., Tino, G., Gonda, I., Haworth, C. & Froehlich, J., 18 Jun 2020, In : European Respiratory Journal. 55, 6

Research output: Contribution to journalArticle

2013

External validity of randomized controlled trials of glycaemic control and vascular disease: how representative are participants?

Saunders, C., Byrne, C. D., Guthrie, B., Lindsay, R. S., Mcknight, J. A., Philip, S., Sattar, N., Walker, J. J., Wild, S. H., Brady, I., Chalmers, J., Colhoun, H., Cunningham, S., Elder, R., Emslie-Smith, A., Fischbacher, C., Govan, L., Jones, N., Leese, G., Levine, D. & 6 others, Livingstone, S., Looker, H., McAlpine, R., Morris, A., Pearson, D. & Petrie, J., 2013, In : Diabetic Medicine. 30, 3, p. 300-308 9 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)
2020

Increased Chitotriosidase is Associated with Aspergillus and Frequent Exacerbations in South-East Asians with Bronchiectasis

Poh, T. Y., Tiew, P. Y., Hou Lim, A. Y., Thng, K. X., Binte Mohamed Ali, N. A., Narayana, J. K., Aogáin, M. M., Tien, Z., Chew, W. M., Wai Chan, A. K., Keir, H. R., Dicker, A. J., Hassan, T. M., Xu, H., Tee, A. K. H., Ong, T. H., Koh, M. S., Abisheganaden, J. A., Chalmers, J. D. & Chotirmall, S. H., 14 Mar 2020, In : Chest.

Research output: Contribution to journalArticle

2014

A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections

Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D., Feb 2014, In : Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2017

New therapies for the prevention and treatment of exacerbations of bronchiectasis

Abo-Leyah, H. & Chalmers, J. D., May 2017, In : Current Opinion in Pulmonary Medicine. 23, 3, p. 218-224 7 p.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
181 Downloads (Pure)
2014

Simplification of the IDSA/ATS criteria for severe CAP using meta-analysis and observational data

Salih, W., Schembri, S. & Chalmers, J. D., 1 Mar 2014, In : European Respiratory Journal. 43, 3, p. 842-851 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2020

Variability in airway inflammation, symptoms, lung function and reliever use in asthma: anti-inflammatory reliever hypothesis and STIFLE study design

Harrison, T., Pavord, I. D., Chalmers, J. D., Whelan, G., Fagerås, M., Rutgersson, A., Belton, L., Siddiqui, S. & Gustafson, P., 8 Jun 2020, In : ERJ Open Research. 6, 2, p. 1-10 10 p., 00333.

Research output: Contribution to journalArticle

Open Access
File
5 Downloads (Pure)
2016

Macrolide antibiotics for non-cystic fibrosis bronchiectasis

Kelly, C., Evans, D. J., Chalmers, J. D., Crossingham, I., Spencer, S., Relph, N., Felix, L. M. & Milan, S. J., 21 Oct 2016, In : Cochrane Database of Systematic Reviews. 10, p. 1-11 13 p., CD012406.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
147 Downloads (Pure)
2015

State of the art review: management of bronchiectasis in adults

Chalmers, J. D., Aliberti, S. & Blasi, F., 1 May 2015, In : European Respiratory Journal. 45, 5, p. 1446-1462 12 p.

Research output: Contribution to journalArticle

128 Citations (Scopus)
2018

Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity

Flume, P. A., Chalmers, J. D. & Olivier, K. N., 8 Sep 2018, In : The Lancet. 392, 10150, p. 880-890 11 p.

Research output: Contribution to journalReview article

Open Access
File
44 Citations (Scopus)
238 Downloads (Pure)
2014

Critical care transition and prevention of ICU readmissions: a bridge over troubled waters*

Chalmers, J. D. & Black, E., Jan 2014, In : Critical Care Medicine. 42, 1, p. 216-217 2 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)
2017

Raising awareness of bronchiectasis in primary care: overview of diagnosis and management strategies in adults

Chalmers, J. D. & Sethi, S., 13 Mar 2017, In : NPJ Primary Care Respiratory Medicine. 27, p. 1-9 9 p., 18.

Research output: Contribution to journalReview article

Open Access
File
16 Citations (Scopus)
160 Downloads (Pure)
2018

British Thoracic Society guideline for bronchiectasis in adults

Hill, A. T., Sullivan, A. L., Chalmers, J. D., De Soyza, A., Elborn, J. S., Floto, R. A., Grillo, L., Gruffydd-Jones, K., Harvey, A., Haworth, C. S., Hiscocks, E., Hurst, J. R., Johnson, C., Kelleher, W. P., Bedi, P., Payne, K., Saleh, H., Screaton, N. J., Smith, M., Tunney, M. & 3 others, Whitters, D., Wilson, R. & Loebinger, M. R., 1 Dec 2018, In : BMJ Open Respiratory Research. 5, 1, 16 p., e000348.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
127 Downloads (Pure)
2016

Diagnostic challenges of bronchiectasis

Suarez-Cuartin, G., Chalmers, J. D. & Sibila, O., 1 Jul 2016, In : Respiratory Medicine. 116, p. 70-77 8 p.

Research output: Contribution to journalReview article

Open Access
File
15 Citations (Scopus)
172 Downloads (Pure)
2018

A systematic review of clinical trial registration in major respiratory journals 2010-2018

Suntila, N. S. M., Smith, A., Al-Dabbagh, Y. & Chalmers, J. D., 6 Dec 2018, In : European Respiratory Journal. 52, 6, 1801491.

Research output: Contribution to journalLetter

Open Access
File
69 Downloads (Pure)
2015

Outcomes in patients with community-acquired pneumonia admitted to the intensive care unit

Cavallazzi, R., Wiemken, T., Arnold, F. W., Luna, C. M., Bordon, J., Kelley, R., Feldman, C., Chalmers, J. D., Torres, A. & Ramirez, J., Jun 2015, In : Respiratory Medicine. 109, 6, p. 743-750 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2013

The role of bacteria and viruses in chronic obstructive pulmonary disease

Valand, K. & Chalmers, J. D., 2013, In : Current Respiratory Medicine Reviews. 9, 6, p. 360-371 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016

Microbial dysbiosis after lung transplantation

Chalmers, J. D., 15 Nov 2016, In : American Journal of Respiratory and Critical Care Medicine. 194, 10, p. 1184-1186 3 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)
2018
Open Access
File
6 Citations (Scopus)
171 Downloads (Pure)
2013
137 Citations (Scopus)
2015

No strong relationship between components of the lectin pathway of complement and susceptibility to pulmonary tuberculosis

Chalmers, J. D., Matsushita, M., Kilpatrick, D. C. & Hill, A. T., Aug 2015, In : Inflammation. 38, 4, p. 1731-1737 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2018

Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a Multinational Point Prevalence Study of Hospitalised Patients

Restrepo, M. I., Babu, B. L., Reyes, L. F., Chalmers, J. D., Soni, N. J., Sibila, O., Faverio, P., Cilloniz, C., Rodriguez-Cintron, W. & Aliberti, S., 9 Aug 2018, In : European Respiratory Journal. 52, 2, 1701190.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
53 Downloads (Pure)

Bronchiectasis: a case-based approach to investigation and management

Contarini, M., Finch, S. & Chalmers, J. D., 30 Sep 2018, In : European Respiratory Review. 27, 149, p. 1-13 13 p., 180016.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
137 Downloads (Pure)
2011

Epidemiology, antibiotic therapy, and clinical outcomes in health care-associated pneumonia: a UK cohort study

Chalmers, J. D., Taylor, J. K., Singanayagam, A., Fleming, G. B., Akram, A. R., Mandal, P., Choudhury, G. & Hill, A. T., 15 Jul 2011, In : Clinical Infectious Diseases. 53, 2, p. 107-13 7 p.

Research output: Contribution to journalArticle

174 Citations (Scopus)
2016

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

Chalmers, J. D., Dicker, A., Woodhead, M. & Madhava, H., 11 May 2016, In : BMC Pulmonary Medicine. 16, 1, p. 1-11 11 p., 77.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
202 Downloads (Pure)
2017

The microbiome in respiratory medicine: current challenges and future perspectives

Faner, R., Sibila, O., Agustí, A., Bernasconi, E., Chalmers, J. D., Huffnagle, G. B., Manichanh, C., Molyneaux, P. L., Paredes, R., Pérez Brocal, V., Ponomarenko, J., Sethi, S., Dorca, J. & Monsó, E., 1 Apr 2017, In : European Respiratory Journal. 49, 4, 1602086.

Research output: Contribution to journalReview article

63 Citations (Scopus)
2018

The Italian registry of pulmonary non-tuberculous mycobacteria - IRENE: The study protocol

IRENE Network, Aliberti, S., Codecasa, L. R., Gori, A., Sotgiu, G., Spotti, M., Di Biagio, A., Calcagno, A., Nardini, S., Assael, B. M., Tortoli, E., Besozzi, G., Ferrarese, M., Matteelli, A., Girardi, E., De Lorenzo, S., Seia, M., Gramegna, A., Del Prato, B., Terranova, L. & 11 others, Oriano, M., Sverzellati, N., Mirsaeidi, M., Chalmers, J. D., Haworth, C. S., Loebinger, M. R., Aksamit, T., Winthrop, K., Ringshausen, F. C., Previdi, G. & Blasi, F., 9 Aug 2018, In : Multidisciplinary Respiratory Medicine. 13, Suppl. 1, 6 p., 33.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
136 Downloads (Pure)
2015

Empirical antibiotic treatment for community-acquired pneumonia: new perspectives

Cutts, A., McAllister, K. & Chalmers, J. D., Jul 2015, In : Clinical Pulmonary Medicine. 22, 4, p. 192-198 7 p.

Research output: Contribution to journalArticle

2014

Reply to Livorsi and Eckerle

Salih, W., Rother, C. & Chalmers, J. D., 2014, In : Clinical Infectious Diseases. 59, 4, p. 610-611 2 p.

Research output: Contribution to journalArticle

2017

10 years since TORCH: shining a new light on the risks of inhaled corticosteroids in COPD

Chalmers, J. D. & Keir, H. R., 1 Sep 2017, In : European Respiratory Journal. 50, 3, 5 p., 1701582.

Research output: Contribution to journalEditorial

3 Citations (Scopus)
2016

The type VII secretion system of Staphylococcus aureus secretes a nuclease toxin that targets competitor bacteria

Cao, Z., Kneuper, H., Casabona, M. G., Chalmers, J. D. & Palmer, T., 10 Oct 2016, In : Nature Microbiology. 2, p. 1-11 11 p., 16183.

Research output: Contribution to journalArticle

Open Access
File
70 Citations (Scopus)
292 Downloads (Pure)
2019

The microbiome in bronchiectasis

Richardson, H., Dicker, A. J., Barclay, H. & Chalmers, J. D., 30 Sep 2019, In : European Respiratory Review. 28, 153, p. 1-10 10 p., 190048.

Research output: Contribution to journalArticle

Open Access
File
82 Downloads (Pure)

Pregnancy Zone Protein is Associated with Airway Infection, Neutrophil Extracellular Trap Formation and Disease Severity in Bronchiectasis

Finch, S., Shoemark, A., Dicker, A. J., Keir, H. R., Smith, A., Ong, S., Tan, B., Choi, J., Fardon, T. C., Cassidy, D., Huang, J. T. J. & Chalmers, J. D., 15 Oct 2019, In : American Journal of Respiratory and Critical Care Medicine. 200, 8, p. 992-1001 10 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
135 Downloads (Pure)
2017

The heterogeneity of systemic inflammation in bronchiectasis

Saleh, A. D., Chalmers, J. D., De Soyza, A., Fardon, T. C., Koustas, S. O., Scott, J., Simpson, A. J., Brown, J. S. & Hurst, J. R., Jun 2017, In : Respiratory Medicine. 127, p. 33-39 7 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
192 Downloads (Pure)
2020

The Sputum Microbiome, Airway Inflammation and Mortality in Chronic Obstructive Pulmonary Disease

Dicker, A. J., Huang, J. T. J., Lonergan, M., Keir, H. R., Fong, C. J., Tan, B., Cassidy, A. J., Finch, S., Mullerova, H., Miller, B. E., Tal-Singer, R. & Chalmers, J. D., 28 Apr 2020, In : Journal of Allergy and Clinical Immunology. 10 p.

Research output: Contribution to journalArticle

2014

Macrolides and mortality in severe community-acquired pneumonia*

Chalmers, J. D., Feb 2014, In : Critical Care Medicine. 42, 2, p. 475-477 3 p.

Research output: Contribution to journalEditorial

2019

Same meat, different gravy: ignore the new names of mycobacteria

Tortoli, E., Brown-Elliott, B. A., Chalmers, J. D., Cirillo, D. M., Daley, C. L., Emler, S., Floto, R. A., Garcia, M. J., Hoefsloot, W., Koh, W-J., Lange, C., Loebinger, M., Maurer, F. P., Morimoto, K., Niemann, S., Richter, E., Turenne, C. Y., Vasireddy, R., Vasireddy, S., Wagner, D. & 3 others, Wallace, R. J., Wengenack, N. & van Ingen, J., 11 Jul 2019, In : The European respiratory journal. 54, 1, p. 1-3 3 p., 1900795.

Research output: Contribution to journalEditorial

2017

Neutrophil elastase activity is associated with exacerbations and lung function decline in Bronchiectasis

Chalmers, J. D., Moffitt, K. L., Suarez-Cuartin, G., Sibila, O., Finch, S., Furrie, E., Dicker, A., Wrobel, K., Elborn, J. S., Walker, B., Martin, S. L., Marshall, S. E., Huang, J. T-J. & Fardon, T. C., 15 May 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 10, p. 1384-1393 10 p.

Research output: Contribution to journalArticle

Open Access
File
81 Citations (Scopus)
146 Downloads (Pure)
2019

Single-inhaler triple therapy in patients with chronic obstructive pulmonary disease: a systematic review

Langham, S., Lewis, J., Pooley, N., Embleton, N., Langham, J., Han, M. K. & Chalmers, J. D., 4 Nov 2019, In : Respiratory Research. 20, p. 1-13 13 p., 242.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
80 Downloads (Pure)
2017

Community-acquired pneumonia in the United Kingdom: a call to action

Chalmers, J., Campling, J., Ellsbury, G., Hawkey, P. M., Madhava, H. & Slack, M., 5 Oct 2017, In : Pneumonia . 9, 6 p., 15.

Research output: Contribution to journalComment/debate

Open Access
File
176 Downloads (Pure)
2019

The economic burden of bronchiectasis - known and unknown: a systematic review

Goeminne, P. C., Hernandez, F., Diel, R., Filonenko, A., Hughes, R., Juelich, F., Solomon, G. M., Upton, A., Wichmann, K., Xu, W. & Chalmers, J. D., 28 Feb 2019, In : BMC Pulmonary Medicine. 19, 1, p. 1-11 11 p., 54.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
130 Downloads (Pure)
2014

Preventing arterial catheter-associated bloodstream infections: common sense and chlorhexidine

Chalmers, J. D. & Aliberti, S., Jun 2014, In : Critical Care Medicine. 42, 6, p. 1533-1534 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Evaluation of active neutrophil elastase in sputum of bronchiectasis and cystic fibrosis patients: A comparison among different techniques

Oriano, M., Terranova, L., Sotgiu, G., Saderi, L., Bellofiore, A., Retucci, M., Marotta, C., Gramegna, A., Miglietta, D., Carnini, C., Marchisio, P., Chalmers, J. D., Aliberti, S. & Blasi, F., Dec 2019, In : Pulmonary Pharmacology & Therapeutics. 59, p. 1-6 6 p., 101856.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018

Get together to increase awareness in bronchiectasis: A report of the 2nd World Bronchiectasis Conference

Aliberti, S. & Chalmers, J. D., 9 Aug 2018, In : Multidisciplinary Respiratory Medicine. 13, Suppl 1, 3 p., 28.

Research output: Contribution to journalEditorial

Open Access
File
1 Citation (Scopus)
120 Downloads (Pure)
2017

Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling

Reyes, L. F., Restrepo, M. I., Hinojosa, C. A., Soni, N. J., Anzueto, A., Babu, B. L., Gonzalez-Juarbe, N., Rodriguez, A. H., Jimenez, A., Chalmers, J. D., Aliberti, S., Sibila, O., Winter, V. T., Coalson, J. J., Giavedoni, L. D., Dela Cruz, C. S., Waterer, G. W., Witzenrath, M., Suttorp, N., Dube, P. H. & 1 others, Orihuela, C. J., 1 Sep 2017, In : American Journal of Respiratory and Critical Care Medicine. 196, 5, p. 609-620 12 p.

Research output: Contribution to journalArticle

Open Access
File
39 Citations (Scopus)
302 Downloads (Pure)