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Author

  • Thomas MacDonald
2013

Changing face of multiple sclerosis in the United kingdom 1990-2010: an incidence and prevalence study

Mackenzie, I. S., Morant, S. V., Bloomfield, G. A., Macdonald, T. M. & O'Riordan, J. I., Nov 2013, In : Journal of Neurology, Neurosurgery and Psychiatry. 84, 11, 1 p., ABN Abstracts 027.

Research output: Contribution to journalMeeting abstract

2011

Pilot Swine Flu Vaccination Active Surveillance Study: Final Results

Layton, D., Dryburgh, M., Mantay, B., MacDonald, T. M., Shakir, S. A. W. & MacKenzie, I. S., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, p. S86-S87 2 p.

Research output: Contribution to journalBook/Film/Article review

6 Citations (Scopus)
2012

Appendicectomy is associated with increased pregnancy rate: a cohort study

Wei, L., Macdonald, T. M. & Shimi, S. M., Dec 2012, In : Annals of Surgery. 256, 6, p. 1039-1044 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2014

The authors reply

Wei, L., Macdonald, T. M. & Murphy, M. J., Jan 2014, In : Kidney International. 85, 1, p. 211 1 p.

Research output: Contribution to journalLetter

2012

Media campaign for recruitment to a streamlined safety trial in Scotland

Wei, L., Hapca, A., Mackenzie, I. S. & MacDonald, T. M., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement s3, p. 128-128 1 p., 272.

Research output: Contribution to journalMeeting abstract

2011

Managing security and privacy concerns over data storage in healthcare research

Mackenzie, I. S., Mantay, B. J., McDonnell, P. G., Wei, L. & MacDonald, T. M., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, 8, p. 885-893 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2012

Effectiveness of statins in chronic kidney disease

Sheng, X., Macdonald, T. M., Wei, L. & Murphy, M. J., Jul 2012, In : QJM : an International Journal of Medicine. 105, 7, p. 641-648 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Spironolactone and the risk of breast cancer: a cohort study

Mackenzie, I. S., MacDonald, T. M., Thompson, A. M., Morant, S. & Wei, L., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement s3, p. 258-258 1 p., 550.

Research output: Contribution to journalMeeting abstract

2011
2013

Pioglitazone and bladder cancer: A propensity score matched cohort study

Wei, L., Macdonald, T. M. & Mackenzie, I. S., Jan 2013, In : British Journal of Clinical Pharmacology. 75, 1, p. 254-259 6 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)
2011

Managing security and privacy concerns over data storage in healthcare research

Mackenzie, I. S., Mantay, B. J., McDonnell, P. G., Wei, L. & MacDonald, T. M., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, 8, p. 885-893 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
6 Citations (Scopus)
2012
28 Citations (Scopus)
2011

Increased Risk of Osteoporotic Fracture in the Thyroid Population

Flynn, R. W. V., Bonellie, S., MacDonald, T. M. & Leese, G. P., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, S1, p. S29-S30 2 p.

Research output: Contribution to journalSpecial issue

6 Citations (Scopus)
2012

Drop-out rates in patients with and without screening period in the SCOT Trial

Wei, L., MacDonald, T. M. & SCOT Study Grp Collaborators, Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement S3, p. 87-87 1 p., 183.

Research output: Contribution to journalMeeting abstract

4 Citations (Scopus)

An efficient and inexpensive system for the distribution and tracking of investigational medicinal products in streamlined safety trials

Flynn, R. W., McDonnell, P. G., Mackenzie, I. S., Wei, L. & MacDonald, T. M., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement s3, p. 124-124 1 p., 263.

Research output: Contribution to journalMeeting abstract

2011
6 Citations (Scopus)
2017

Erratum: The British Society for Rheumatology Guideline for the Management of Gout

Hui, M., Carr, A., Cameron, S., Davenport, G., Doherty, M., Forrester, H., Jenkins, W., Jordan, K. M., Mallen, C. D., MacDonald, T., Nuki, G., Pywell, A., Zhang, W. & Roddy, E., 1 Jul 2017, In : Rheumatology. 56, 7, p. 1246 1 p.

Research output: Contribution to journalArticle

2012
14 Citations (Scopus)
51 Citations (Scopus)
2019

Allopurinol treatment adversely impacts left ventricular mass regression in patients with well-controlled hypertension

Gingles, C., Symon, R., Gandy, S., Struthers, A., Houston, G., MacDonald, T., Lang, C., Donnan, P. & George, J., Dec 2019, In : Journal of Hypertension. 37, 12, p. 2481-2489 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
141 Downloads (Pure)
2020

Reply

Gingles, C. R., Symon, R., Gandy, S. J., Struthers, A. D., Houston, G., MacDonald, T. M., Lang, C. C., Donnan, P. T. & George, J., 1 Jan 2020, In : Journal of Hypertension. 38, 1, p. 177-178 2 p.

Research output: Contribution to journalLetter

2019

Lowering Uric Acid in Normouricaemic Hypertensive Patients Has an Adverse Effect on Left Ventricular Hypertrophy Regression: Mechanistic Proof of the Urate Paradox

Gingles, C., Symon, R., Gandy, S. J., Struthers, A. D., Houston, G., Macdonald, T. M., Lang, C. C., Donnan, P. T. & George, J., 1 Jul 2019, In : Journal of Hypertension. 37, p. e57

Research output: Contribution to journalMeeting abstract

2014

Cardiovascular risk associated with sodium-containing medicines

Wei, L., Mackenzie, I. S., MacDonald, T. M. & George, J., Nov 2014, In : Expert Opinion on Drug Safety. 13, 11, p. 1515-1523 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effectiveness of newspaper advertising for patient recruitment into a clinical trial

Hapca, A., Jennings, C. G., Wei, L., Wilson, A., MacDonald, T. M. & Mackenzie, I. S., Jun 2014, In : British Journal of Clinical Pharmacology. 77, 6, p. 1064-1072 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2012
3 Citations (Scopus)
2017

Successful recruitment to a large online randomised trial: the TIME study

Rogers, A., Mackenzie, I., Rorie, D. & MacDonald, T., 2 May 2017, Trials: Meeting abstracts from the 4th International Clinical Trials Methodology Conference (ICTMC) and the 38th Annual Meeting of the Society for Clinical Trials. Supplement 1 ed. United Kingdom: BioMed Central, Vol. 18. p. 222-223 2 p. 089. (Trials; vol. 18, no. Suppl. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
594 Downloads (Pure)
2019
Open Access
File
2 Citations (Scopus)
51 Downloads (Pure)
2017
Open Access
File
4 Citations (Scopus)
155 Downloads (Pure)
2018

Investigating Real-World Clopidogrel Pharmacogenetics in Stroke Using a Bioresource Linked to Electronic Medical Records

Tornio, A., Flynn, R., Morant, S., Velten, E., Palmer, C. N. A., MacDonald, T. M. & Doney, A. S. F., 1 Feb 2018, In : Clinical Pharmacology & Therapeutics. 103, 2, p. 281-286 6 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
159 Downloads (Pure)
2017
Open Access
File
8 Citations (Scopus)
319 Downloads (Pure)
2012

Assessing therapies in rare disease patients: re-evaluating the n-of-one crossover design

Wang, J., Morant, S., Ford, I., Flynn, R. W., MacDonald, T. M. & Wei, L., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement s3, p. 126-126 1 p., 267.

Research output: Contribution to journalMeeting abstract

2017

Randomised trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib: The Standard care versus Celecoxib Outcome Trial (SCOT)

MacDonald, T., Hawkey, C. J., Ford, I., McMurray, J. J. V., Scheiman, J. M., Hallas, J., Findlay, E., Grobbee, D. E., Hobbs, FD. R., Ralston, S. H., Reid, D. M., Walters, M., Webster, J., Ruschitzka, F., Ritchie, L. D., Perez-Gutthann, S., Connolly, E., Greenlaw, N., Wilson, A., Wei, L. & 1 others, Mackenzie, I., 14 Jun 2017, In : European Heart Journal. 38, 23, p. 1843-1850 9 p.

Research output: Contribution to journalArticle

Open Access
File
35 Citations (Scopus)
140 Downloads (Pure)

Spironolactone use and risk of incident cancers: a retrospective, matched cohort study

Mackenzie, I. S., Morant, S. V., Wei, L., Thompson, A. M. & MacDonald, T. M., 14 Feb 2017, In : British Journal of Clinical Pharmacology. 83, 3, p. 653-663 11 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
168 Downloads (Pure)
2016

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

Brown, M. J., Williams, B., Morant, S. V., Webb, D. J., Caulfield, M. J., Cruickshank, J. K., Ford, I., McInnes, G., Sever, P., Salsbury, J., Mackenzie, I. S., Padmanabhan, S., MacDonald, T. M. & for the British Hypertension Society's Prevention, Treatment of Hypertension with Algorithm-based Therapy (PATHWAY) Studies Group, Feb 2016, In : The Lancet: Diabetes and Endocrinology. 4, 2, p. 136-147 12 p.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
140 Downloads (Pure)
2020

Impact of EMA regulatory label changes on systemic diclofenac initiation, discontinuation, and switching to other pain medicines in Scotland, England, Denmark, and The Netherlands

Morales, D. R., Morant, S. V., MacDonald, T. M., Mackenzie, I. S., Doney, A. S. F., Mitchell, L., Bennie, M., Robertson, C., Hallas, J., Pottegard, A., Ernst, M. T., Wei, L., Nicholson, L., Morris, C., Herings, R. M. C., Overbeek, J. A., Smits, E. & Flynn, R. W. V., Mar 2020, In : Pharmacoepidemiology and Drug Safety. 29, 3, p. 296-305 10 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
42 Downloads (Pure)
2015
1 Citation (Scopus)
2018

In response to: 'Thyroid hormone replacement - a counterblast to guidelines'

Leese, G. P., Flynn, R. V., MacDonald, T. M., Schofield, C. & Mackie, A. D., Mar 2018, In : Journal of the Royal College of Physicians of Edinburgh. 48, 1, p. 93 1 p.

Research output: Contribution to journalLetter

Open Access
2011

High Sensitivity Cardiac Troponin T is Associated with Silent Cardiac Target Organ Damage in Asymptomatic Primary Prevention Patients

Nadir, M. A., Dow, E., Lang, C. C., Davidson, J., MacDonald, T. & Struthers, A. D., 22 Nov 2011, In : Circulation. 124, 21, p. - 2 p.

Research output: Contribution to journalArticle

2012

A pilot study to investigate the supply of investigational medicinal product to patients via mail in a streamlined safety study

Flynn, R. W., Saywood, W., Mackenzie, I. S., Wei, L. & MacDonald, T. M., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement S3, p. 124-125 2 p., 264.

Research output: Contribution to journalMeeting abstract

2011

Can microalbuminuria identify silent "pancardiac" target organ damage in a non-diabetic primary prevention population?

Nadir, A., Rekhraj, S., Davidson, J., MacDonald, T. M., Lang, C. & Struthers, A. D., Jun 2011, In : Heart. 97, p. A35-A35 1 p.

Research output: Contribution to journalBook/Film/Article review

Managing Security and Privacy Concerns over Data Storage in Healthcare Research

Mackenzie, I. S., Mantay, B. J., McDonnell, P. G., Wei, L. & MacDonald, T. M., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, s1, p. S170-S170 1 p.

Research output: Contribution to journalBook/Film/Article review

6 Citations (Scopus)

Cardiovascular Safety of Lumiracoxib: A Meta-Analysis of Randomised Controlled Trials in Patients with Osteoarthritis

Mackenzie, I. S., Wei, L. & MacDonald, T. M., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, s1, p. S354-S354 1 p.

Research output: Contribution to journalBook/Film/Article review

6 Citations (Scopus)

Hypertriglyceridemia and acute pancreatitis

Murphy, M. J., Sheng, X., MacDonald, T. M. & Wei, L., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, S1, p. S257-S257 1 p., 590.

Research output: Contribution to journalSpecial issue

6 Citations (Scopus)
2012

The comparative effectiveness of statin therapy in selected chronic diseases compared with the remaining population

Sheng, X., Murphy, M. J., MacDonald, T. M. & Wei, L., 30 Aug 2012, In : BMC Public Health. 12, 9 p., 712.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2011

Co-prescription of co-trimoxazole and spironolactone in elderly patients

Wei, L., MacDonald, T. M. & Mackenzie, I. S., 12 Sep 2011, In : BMJ. 343, 7823, p. - 2 p., d5656.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2012

Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study

Mackenzie, I. S., Macdonald, T. M., Thompson, A., Morant, S. & Wei, L., 2012, In : British Medical Journal. 345, p. e4447 12 p., e4447.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2018
Open Access
File
19 Downloads (Pure)
2019

Study Design and Cohort Comparability in a Study of Major Cardiovascular Events in New Users of Prucalopride Versus Polyethylene Glycol 3350

Fortuny, J., Gilsenan, A., Cainzos-Achirica, M., Cantero, O. F., Flynn, R. W. V., Garcia-Rodriguez, L., Kollhorst, B., Karlsson, P., Linnér, L., MacDonald, T. M., Plana, E., Ruigómez, A., Schink, T., Ziemiecki, R. & Andrews, E. B., Oct 2019, In : Drug Safety. 42, 10, p. 1167-1177 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
118 Downloads (Pure)
2018

Ibuprofen and Paracetamol: Acceptably Safe for All?

Pigazzani, F., Mackenzie, I. & MacDonald, T. M., Nov 2018, In : Drug Safety. 41, 11, p. 999-1001 3 p.

Research output: Contribution to journalComment/debate

Open Access
File
2 Citations (Scopus)
154 Downloads (Pure)