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  • Irwin McLean
2012

Scanning Ion Conductance Microscopy of Live Keratinocytes

Hegde, V., Mason, A., Saliev, T., Smith, F., McLean, W. H. I. & Campbell, P. A., 2012, Electron Microscopy and Analysis Group Conference 2011 (EMAG 2011). Bristol: IOP Publishing Ltd., p. - 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)
2015

PCQoL: a quality of life assessment measure for Pachyonychia congenita

Abbas, M., Schwartz, M. E., Smith, F. J. D., McLean, W. H. I. & Hull, P. R., 2015, In : Journal of Cutaneous Medicine and Surgery. 19, 1, p. 57-65 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2013

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis

Ellinghaus, D., Baurecht, H., Esparza-Gordillo, J., Rodríguez, E., Matanovic, A., Marenholz, I., Hübner, N., Schaarschmidt, H., Novak, N., Michel, S., Maintz, L., Werfel, T., Meyer-Hoffert, U., Hotze, M., Prokisch, H., Heim, K., Herder, C., Hirota, T., Tamari, M., Kubo, M. & 29 others, Takahashi, A., Nakamura, Y., Tsoi, L. C., Stuart, P., Elder, J. T., Sun, L., Zuo, X., Yang, S., Zhang, X., Hoffmann, P., Nöthen, M. M., Fölster-Holst, R., Winkelmann, J., Illig, T., Boehm, B. O., Duerr, R. H., Büning, C., Brand, S., Glas, J., McAleer, M. A., Fahy, C. M., Kabesch, M., Brown, S., McLean, W. H. I., Irvine, A. D., Schreiber, S., Lee, Y-A., Franke, A. & Weidinger, S., Jul 2013, In : Nature Genetics. 45, 7, p. 808-812 5 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

Topical formulation for delivery of therapeutic RNA into the epidermis

Hegde, V., Nainamalai, S., Campbell, P. A., Smith, F. J., McLean, I. & Pedrioli, D. M. L., 2013, In : Journal of Investigative Dermatology. 133, S1, p. S143 1 p., 844.

Research output: Contribution to journalMeeting abstract

Recessive mutations in the gene encoding frizzled 6 cause twenty nail dystrophy: Expanding the differential diagnosis for pachyonychia congenita

Wilson, N. J., Hansen, C. D., Azkur, D., Kocabas, C. N., Metin, A., Coskun, Z., Schwartz, M. E., Hull, P. R., McLean, W. H. I. & Smith, F. J. D., Apr 2013, In : Journal of Dermatological Science. 70, 1, p. 58-60 3 p.

Research output: Contribution to journalLetter

14 Citations (Scopus)

A nonsense mutation in the mattrin gene causes the matted mouse phenotype and is a predisposing gene for atopic dermatitis in humans

Goh, C. S., Saunders, S. P., Cole, C., Weidinger, S., Baurecht, H., Lee, Y., Reynolds, N. J., Barker, J. N., Cordell, H. J., Brown, S. J., Irvine, A. D., McLean, I., Sandilands, A. & Fallon, P. G., 2013, In : Journal of Investigative Dermatology. 133, S1, p. S145 1 p., 854.

Research output: Contribution to journalMeeting abstract

2011

Development of quantitative molecular clinical end points for siRNA clinical trials

Hickerson, R. P., Leachman, S. A., Pho, L. N., Gonzalez-Gonzalez, E., Smith, F. J. D., McLean, W. H. I., Contag, C. H., Leake, D., Milstone, L. M. & Kaspar, R. L., May 2011, In : Journal of Investigative Dermatology. 131, 5, p. 1029-1036 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2019

Longitudinal analysis of the effect of water hardness on atopic eczema: evidence for gene-environment interaction

Jabbar-Lopez, Z. K., Craven, J., Logan, K., Greenblatt, D., Marrs, T., Radulovic, S., McLean, W. H. I., Lack, G., Strachan, D. P., Perkin, M. R., Peacock, J. L. & Flohr, C., 10 Oct 2019, In : British Journal of Dermatology. 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2012

Poikiloderma with neutropaenia in a pair of Caucasian dizygotic twins

Rakvit, P., Macfarlane, L., Wen, Y., Brown, S., McLean, W. H. I., Lewis-Jones, S. & Hearn, R. M. R., Jan 2012, In : British Journal of Dermatology. 166, 1, p. E2-E2 1 p., O5.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2015

Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year

Kelleher, M., Dunn-Galvin, A., Hourihane, J. OB., Murray, D., Campbell, L. E., McLean, W. H. I. & Irvine, A. D., Apr 2015, In : Journal of Allergy and Clinical Immunology. 135, 4, p. 930-935.e1 6 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
2013

Generation and characterisation of keratin 7 (K7) knockout mice

Sandilands, A., Smith, F. J. D., Lunny, D. P., Campbell, L. E., Davidson, K. M., MacCallum, S. F., Corden, L. D., Christie, L., Fleming, S., Lane, E. B. & McLean, W. H. I., 31 May 2013, In : PLoS ONE. 8, 5, 11 p., e64404.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2011

Toward a Treatment for Pachyonychia Congenita: Report on the 7th Annual International Pachyonychia Congenita Consortium Meeting

Kaspar, R. L., Leachman, S. A., McLean, W. H. I. & Schwartz, M. E., May 2011, In : Journal of Investigative Dermatology. 131, 5, p. 1011-1014 4 p.

Research output: Contribution to journalComment/debate

12 Citations (Scopus)
2013

A Lack of premature termination codon read-through efficacy of PTC124 (Ataluren) in a diverse array of reporter assays

McElroy, S. P., Nomura, T., Torrie, L. S., Warbrick, E., Gartner, U., Wood, G. & McLean, W. H. I., 2013, In : PLoS Biology. 11, 6, e1001593.

Research output: Contribution to journalArticle

82 Citations (Scopus)
2020

Bathing frequency is associated with skin barrier dysfunction and atopic dermatitis at three months of age

Marrs, T., Perkin, M. R., Logan, K., Craven, J., Radulovic, S., McLean, W. H. I., Versteeg, S. A., van Ree, R., Lack, G., Flohr, C. & EAT Study Team, 26 Apr 2020, In : The Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

2014

Jitter reduction using native fiducials in rotating mirror ultra-fast microphotography

Goh, B. H. T., Khoo, B. C., McLean, W. H. I. & Campbell, P. A., 30 Jun 2014, In : Optics Express. 22, 13, p. 16282-16288 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Keratin 6b variant p.Gly499Ser reported in delayed-onset pachyonychia congenita is a non-pathogenic polymorphism

Smith, F. J. D. & McLean, W. H. I., 3 Dec 2017, In : Journal of Dermatology. 44, 12, p. e312 1 p.

Research output: Contribution to journalLetter

Open Access
File
1 Citation (Scopus)
149 Downloads (Pure)
2015

Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis

Riethmuller, C., McAleer, M. A., Koppes, S. A., Abdayem, R., Franz, J., Haftek, M., Campbell, L. E., MacCallum, S. F., McLean, W. H. I., Irvine, A. D. & Kezic, S., Dec 2015, In : Journal of Allergy and Clinical Immunology. 136, 6, p. 1573-1580.e2 10 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2011

Development of allele-specific therapeutic siRNA for keratin 5 mutations in epidermolysis bullosa simplex

Atkinson, S. D., McGilligan, V. E., Liao, H., Szeverenyi, I., Smith, F. J. D., Moore, C. B. T. & McLean, W. H. I., Oct 2011, In : Journal of Investigative Dermatology. 131, 10, p. 2079-2086 8 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2014

South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin

Thawer-Esmail, F., Jakasa, I., Todd, G., Wen, Y., Brown, S. J., Kroboth, K., Campbell, L. E., O'Regan, G. M., McLean, W. H. I., Irvine, A. D., Kezic, S. & Sandilands, A., Jan 2014, In : Journal of Allergy and Clinical Immunology. 133, 1, p. 280-282.e1-e2 5 p.

Research output: Contribution to journalLetter

44 Citations (Scopus)
2018

Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children

Kono, M., Akiyama, M., Inoue, Y., Nomura, T., Hata, A., Okamoto, Y., Takeichi, T., Muro, Y., McLean, W. H. I., Shimizu, H., Sugiura, K., Suzuki, Y. & Shimojo, N., 19 Jul 2018, In : British Journal of Dermatology. 179, 1, p. 190-191 2 p.

Research output: Contribution to journalLetter

Open Access
File
2 Citations (Scopus)
158 Downloads (Pure)
2011

Paternal germ cell mosaicism in autosomal dominant pachyonychia congenita

Pho, L. N., Smith, F. J. D., Konecki, D., Bale, S., McLean, W. H. I., Cohen, B., Eliason, M. J. & Leachman, S. A., Sep 2011, In : Archives of dermatology. 147, 9, p. 1077-1080 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Array-based sequencing of filaggrin gene for comprehensive detection of disease-associated variants

Wong, X. F. C. C., Denil, S. L. I. J., Foo, J. N., Chen, H., Ling Tay, A. S., Haines, R. L., Tang, M. B. Y., McLean, W. H. I., Sandilands, A., Smith, F. J. D., Lane, E. B., Liu, J. & Common, J. E. A., Feb 2018, In : Journal of Allergy and Clinical Immunology. 141, 2, p. 814-816 3 p.

Research output: Contribution to journalLetter

Open Access
File
18 Citations (Scopus)
275 Downloads (Pure)
2013

Novel mutation in keratin 10 causing autosomal dominant epidermolytic ichthyosis

Lamb, R. C., Terron-Kwiatkowski, A., Lang, J., McLean, W. H. I. & Zamiri, M., 2013, In : British Journal of Dermatology. 169, Suppl. 1, p. 29-30 2 p., P23.

Research output: Contribution to journalMeeting abstract

2016

Filaggrin failure - from ichthyosis vulgaris to atopic eczema and beyond

McLean, W., 26 Sep 2016, In : British Journal of Dermatology. 175, 52, p. 4-7 4 p.

Research output: Contribution to journalReview article

Open Access
File
28 Citations (Scopus)
193 Downloads (Pure)

Skin barrier impairment at birth predicts food allergy at 2 years of age

Kelleher, M. M., Dunn-Galvin, A., Gray, C., Murray, D. M., Kiely, M., Kenny, L., McLean, W. H. I., Irvine, A. D. & Hourihane, J. OB., Apr 2016, In : Journal of Allergy and Clinical Immunology. 137, 4, p. 1111-1116.e1-8 14 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)
2015

Novel TGM5 mutations in acral peeling skin syndrome

van der Velden, J. . J. A. J., van Geel, M., Nellen, R. G. L., Jonkman, M. F., McGrath, J. A., Nanda, A., Sprecher, E., van Steensel, M. A. M., Mclean, W. H. I. & Cassidy, A. J., Apr 2015, In : Experimental Dermatology. 24, 4, p. 285-289 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A. D., Kabesch, M., Lee, Y. A. E., Lieb, W., Marenholz, I., McLean, W. H. I. & 19 others, Morris, D. W., Mrowietz, U., Nair, R., Nöthen, M. M., Novak, N., O'Regan, G. M., PAGE Consortium, Schreiber, S., Smith, C., Strauch, K., Stuart, P. E., Trembath, R., Tsoi, L. C., Weichenthal, M., Barker, J., Elder, J. T., Weidinger, S., Cordell, H. J. & Brown, S. J., 8 Jan 2015, In : American Journal of Human Genetics. 96, 1, p. 104-120 17 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)
2012

Germline Mutation in EXPH5 Implicates the Rab27B Effector Protein Slac2-b in Inherited Skin Fragility

McGrath, J. A., Stone, K. L., Begum, R., Simpson, M. A., Dopping-Hepenstal, P. J., Liu, L., McMillan, J. R., South, A. P., Pourreyron, C., McLean, W. H. I., Martinez, A. E., Mellerio, J. E. & Parsons, M., 7 Dec 2012, In : American Journal of Human Genetics. 91, 6, p. 1115-1121 7 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2013

Keratin 9 Is Required for the Structural Integrity and Terminal Differentiation of the Palmoplantar Epidermis

Fu, D. J., Thomson, C., Lunny, D. P., Dopping-Hepenstal, P. J., McGrath, J. A., Smith, F. J. D., McLean, W. H. I. & Leslie Pedrioli, D. M., 2013, In : Journal of Investigative Dermatology. n/a, n/a.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2014

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

Cole, C., Kroboth, K., Schurch, N. J., Sandilands, A., Sherstnev, A., O'Regan, G. M., Watson, R. M., McLean, W. H. I., Barton, G. J., Irvine, A. D. & Brown, S. J., Jul 2014, In : Journal of Allergy and Clinical Immunology. 134, 1, p. 82-91 10 p.

Research output: Contribution to journalArticle

Open Access
File
75 Citations (Scopus)
184 Downloads (Pure)
2012

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Genetic Anal Psoriasis Consortium, Wellcome Trust Case Control, 1 Dec 2012, In : Nature Genetics. 44, 12, p. 1341-1348 8 p.

Research output: Contribution to journalArticle

544 Citations (Scopus)
2018

Patients with atopic dermatitis with filaggrin loss-of-function mutations show good but lower responses to immunosuppressive treatment

Roekevisch, E., Leeflang, M. M. G., Schram, M. E., Campbell, L. E., Irwin McLean, W. H., Kezic, S., Bos, J. D., Spuls, P. I. & Middelkamp-Hup, M. A., 8 Jan 2018, In : British Journal of Dermatology. 177, 6, p. 1745-1746 2 p.

Research output: Contribution to journalLetter

Open Access
File
3 Citations (Scopus)
146 Downloads (Pure)
2014

Mutations in GRHL2 result in an autosomal-recessive ectodermal dysplasia syndrome

Petrof, G., Nanda, A., Howden, J., Takeichi, T., McMillan, J. R., Aristodemou, S., Ozoemena, L., Liu, L., South, A. P., Pourreyron, C., Dafou, D., Proudfoot, L. E., Al-Ajmi, H., Akiyama, M., McLean, W. H. I., Simpson, M. A., Parsons, M. & McGrath, J. A., 4 Sep 2014, In : American Journal of Human Genetics. 95, 3, p. 308-314 7 p.

Research output: Contribution to journalArticle

File
33 Citations (Scopus)
146 Downloads (Pure)
2013

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

Saunders, S. P., Goh, C. S. M., Brown, S. J., Palmer, C. N. A., Porter, R. M., Cole, C., Campbell, L. E., Gierlinski, M., Barton, G. J., Schneider, G., Balmain, A., Prescott, A. R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y-A., Tavendale, R., Mukhopadhyay, S., Turner, S. W. & 14 others, Madhok, V. B., Sullivan, F. M., Relton, C., Burn, J., Meggitt, S., Smith, C. H., Allen, M. A., Barker, J. N. W. N., Reynolds, N. J., Cordell, H. J., Irvine, A. D., McLean, W. H. I., Sandilands, A. & Fallon, P. G., Nov 2013, In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1121-1129 9 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)
2014

The molecular genetic analysis of the expanding pachyonychia congenita case collection

Wilson, N. J., O'Toole, E., Milstone, L. M., Hansen, C. D., Shepherd, A. A., Al-Asadi, E., Schwartz, M. E., McLean, W. H. I., Sprecher, E. & Smith, F. J. D., Aug 2014, In : British Journal of Dermatology. 171, 2, p. 343-355 13 p., 12958.

Research output: Contribution to journalArticle

Open Access
File
36 Citations (Scopus)
152 Downloads (Pure)
2018

Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies.

Portnoi, M-F., Dumargne, M-C., Rojo, S., Witchel, S. F., Duncan, A. J., Eozenou, C., Bignon-Topalovic, J., Yatsenko, S. A., Rajkovic, A., Reyes-Mugica, M., Almstrup, K., Fusee, L., Srivastava, Y., Chantot-Bastaraud, S., Hyon, C., Louis-Sylvestre, C., Validire, P., de Malleray Pichard, C., Ravel, C., Christin-Maitre, S. & 18 others, Brauner, R., Rossetti, R., Persani, L., Charreau, E. H., Dain, L., Chiauzzi, V. A., Mazen, I., Rouba, H., Schluth-Bolard, C., MacGowan, S., McLean, W. H. I., Patin, E., Rajpert-De Meyts, E., Jauch, R., Achermann, J. C., Siffroi, J-P., McElreavey, K. & Bashamboo, A., 1 Apr 2018, In : Human Molecular Genetics. 27, 7, p. 1228-1240 13 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
163 Downloads (Pure)
2014

Punctate Palmoplantar Keratoderma Type 1: A Novel AAGAB Mutation and Efficacy of Etretinate

Nomura, T., Yoneta, A., Pohler, E., Suzuki, S., Osawa, R., Mizuno, O., Ohguchi, Y., Nomura, Y., Yamashita, T., McLean, W. H. I. & Shimizu, H., 2014, In : Acta Dermato-Venereologica. 95, 1, p. 110-111 2 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2011

Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations

Chen, H., Common, J. E. A., Haines, R. L., Balakrishnan, A., Brown, S. J., Goh, C. S. M., Cordell, H. J., Sandilands, A., Campbell, L. E., Kroboth, K., Irvine, A. D., Goh, D. L. M., Tang, M. B. Y., van Bever, H. P., Giam, Y. C., McLean, W. H. I. & Lane, E. B., Jul 2011, In : British Journal of Dermatology. 165, 1, p. 106-114 9 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity

Kezic, S., O'Regan, G. M., Yau, N., Sandilands, A., Chen, H., Campbell, L. E., Kroboth, K., Watson, R., Rowland, M., McLean, W. H. I. & Irvine, A. D., 2011, In : Allergy. 66, 7, p. 934-940 7 p.

Research output: Contribution to journalArticle

160 Citations (Scopus)
2015

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D. P., Curtin, J. A., Bønnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A. C., Thyssen, J. P., Den Dekker, H. T., Ferreira, M. A., Altmaier, E., Sleiman, P. M. A., Xiao, F. L., Gonzalez, J. R., Marenholz, I. & 130 others, Kalb, B., Pino-Yanes, M., Xu, C. J., Carstensen, L., Groen-Blokhuis, M. M., Venturini, C., Pennell, C. E., Barton, S. J., Levin, A. M., Curjuric, I., Bustamante, M., Kreiner-Møller, E., Lockett, G. A., Bacelis, J., Bunyavanich, S., Myers, R. A., Matanovic, A., Kumar, A., Tung, J. Y., Hirota, T., Kubo, M., McArdle, W. L., Henderson, A. J., Kemp, J. P., Zheng, J., Smith, G. D., Rüschendorf, F., Bauerfeind, A., Lee-Kirsch, M. A., Arnold, A., Homuth, G., Schmidt, C. O., Mangold, E., Cichon, S., Keil, T., Rodríguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Fölster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L. L., Grarup, N., De Jongste, J. C., Rivadeneira, F., Hofman, A., Jaddoe, V. W. V., Pasmans, S. G. M. A., Elbert, N. J., Uitterlinden, A. G., Marks, G. B., Thompson, P. J., Matheson, M. C., Robertson, C. F., Ried, J. S., Li, J., Zuo, X. B., Zheng, X. D., Yin, X. Y., Sun, L. D., McAleer, M. A., O'Regan, G. M., Fahy, C. M. R., Campbell, L. E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D. S., Feenstra, B., Geller, F., Hottenga, J. J., Middeldorp, C. M., Hysi, P., Bataille, V., Spector, T., Tiesler, C. M. T., Thiering, E., Pahukasahasram, B., Yang, J. J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C. L., Myhre, R., Nystad, W., Custovic, A., Weiss, S. T., Meyers, D. A., Söderhäll, C., Melén, E., Ober, C., Raby, B. A., Simpson, A., Jacobsson, B., Holloway, J. W., Bisgaard, H., Sunyer, J., Probst-Hensch, N. M., Williams, L. K., Godfrey, K. M., Wang, C. A., Boomsma, D. I., Melbye, M., Koppelman, G. H., Jarvis, D., McLean, W. H. I., Irvine, A. D., Zhang, X. J., Hakonarson, H., Gieger, C., Burchard, E. G., Martin, N. G., Duijts, L., Linneberg, A., Jarvelin, M. R., Nöthen, M. M., Lau, S., Hübner, N., Lee, Y. A., Tamari, M., Hinds, D. A., Glass, D., Brown, S. J., Heinrich, J., Evans, D. M. & Weidinger, S., Dec 2015, In : Nature Genetics. 47, 12, p. 1449-1456 8 p.

Research output: Contribution to journalLetter

211 Citations (Scopus)
2016

CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting

Courtney, D. G., Moore, J. E., Atkinson, S. D., Maurizi, E., Allen, E. H. A., Leslie Pedrioli, D. M. L., Mclean, W. H. I., Nesbit, M. A. & Moore, C. B. T., 2016, In : Gene Therapy. 23, 1, p. 108-112

Research output: Contribution to journalArticle

Open Access
File
59 Citations (Scopus)
143 Downloads (Pure)
2011

Identification of a novel C16orf57 mutation in Athabaskan patients wth poikiloderma with neutropenia

Clericuzio, C., Harutyunyan, K., Jin, W., Erickson, R. P., Irvine, A. D., McLean, W. H. I., Wen, Y., Bagatell, R., Griffin, T. A., Shwayder, T. A., Plon, S. E. & Wang, L. L., Feb 2011, In : American Journal of Medical Genetics Part A. 155A, 2, p. 337-342 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2013

Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis

Visser, M. J., Landeck, L., Campbell, L. E., McLean, W. H. I., Weidinger, S., Calkoen, F., John, S. M. & Kezic, S., 2013, In : British Journal of Dermatology. 168, 2, p. 326-332 7 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

Weidinger, S., Willis-Owen, S. A. G., Kamatani, Y., Baurecht, H., Morar, N., Liang, L., Edser, P., Street, T., Rodriguez, E., O'Regan, G. M., Beattie, P., Fölster-Holst, R., Franke, A., Novak, N., Fahy, C. M., Winge, M. C. G., Kabesch, M., Illig, T., Heath, S., Söderhäll, C. & 13 others, Melén, E., Pershagen, G., Kere, J., Bradley, M., Lieden, A., Nordenskjold, M., Harper, J. I., McLean, W. H. I., Brown, S. J., Cookson, W. O. C., Lathrop, G. M., Irvine, A. D. & Moffatt, M. F., Dec 2013, In : Human Molecular Genetics. 22, 23, p. 4841-4856 16 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)
2016

Association between domestic water hardness, chlorine, and atopic dermatitis risk in early life: A population-based cross-sectional study

Perkin, M. R., Craven, J., Logan, K., Strachan, D., Marrs, T., Radulovic, S., Campbell, L. E., MacCallum, S. F., McLean, W. H. I., Lack, G. & Flohr, C., Aug 2016, In : Journal of Allergy and Clinical Immunology. 138, 2, p. 509-516 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2012

Filaggrin mutations: Prognosis and response to therapy overtime

Margolis, D. J., Mitra, N., Sandilands, A., McLean, I. & Rebbeck, T., May 2012, In : Journal of Investigative Dermatology. 132, p. S41-S41 1 p.

Research output: Contribution to journalArticle

2013

Reliability and validity of genotyping filaggrin null mutations

Margolis, D. J., Apter, A. J., Mitra, N., Gupta, J., Hoffstad, O., Papadopoulos, M., Rebbeck, T. R., MacCallum, S., Campbell, L. E., Sandilands, A. & McLean, W. H. I., Apr 2013, In : Journal of Dermatological Science. 70, 1, p. 67-68 2 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status

Asai, Y., Greenwood, C., Hull, P. R., Alizadehfar, R., Ben-Shoshan, M., Brown, S. J., Campbell, L., Michel, D. L., Bussières, J., Rousseau, F., Fujiwara, T. M., Morgan, K., Irvine, A. D., McLean, W. H. I. & Clarke, A., Jul 2013, In : Journal of Allergy and Clinical Immunology. 132, 1, p. 239-242.e7 4 p.

Research output: Contribution to journalLetter

35 Citations (Scopus)

Possibilities for human skin characterization based on strongly reduced Raman spectroscopic information

Baclig, A. C., Bakker Schut, T. C., O'Regan, G. M., Irvine, A. D., McLean, W. H. I., Puppels, G. J. & Caspers, P. J., 2013, In : Journal of Raman Spectroscopy. 44, 3, p. 340-345 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)