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2020
Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila
Deng, P., Khan, A., Jacobson, D., Sambrani, N., McGurk, L., Li, X., Jayasree, A., Hejatko, J., Shohat-Ophir, G., O'Connell, M. A., Li, J. B. & Keegan, L. P., 27 Mar 2020, In: Nature Communications. 11, 1, p. 1580 1580.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)52 Downloads (Pure) -
First person - Leeanne McGurk
McGurk, L., Jun 2020, In: Journal of Cell Science. 133, 12, 2 p., jcs.248773.Research output: Contribution to journal › Comment/debate › peer-review
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Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy
Khan, A., Paro, S., McGurk, L., Sambrani, N., Hogg, M. C., Brindle, J., Pennetta, G., Keegan, L. P. & O'Connell, M. A., 14 Feb 2020, In: BMC Biology. 18, 1, 16 p., 15.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)50 Downloads (Pure) -
TDP-43, a protein central to amyotrophic lateral sclerosis, is destabilized by tankyrase-1 and -2
McGurk, L., Rifai, O. & Bonini, N. M., 23 Jun 2020, In: Journal of Cell Science. 133, 12Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)19 Downloads (Pure) -
2019
Poly(ADP-Ribosylation) in Age-Related Neurological Disease
McGurk, L., Rifai, O. M. & Bonini, N. M., Aug 2019, In: Trends in Genetics. 35, 8, p. 601-613 13 p.Research output: Contribution to journal › Review article › peer-review
3 Citations (Scopus) -
2018
Nuclear poly(ADP-ribose) activity is a therapeutic target in amyotrophic lateral sclerosis
McGurk, L., Mojsilovic-Petrovic, J., Van Deerlin, V. M., Shorter, J., Kalb, R. G., Lee, V. M., Trojanowski, J. Q., Lee, E. B. & Bonini, N. M., 29 Aug 2018, In: Acta Neuropathologica Communications. 6, 1, p. 1-15 15 p., 84.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)70 Downloads (Pure) -
Poly(ADP-ribose) Engages the TDP-43 Nuclear-Localization Sequence to Regulate Granulo-Filamentous Aggregation
McGurk, L., Gomes, E., Guo, L., Shorter, J. & Bonini, N. M., 26 Dec 2018, In: Biochemistry. 57, 51, p. 6923-6926 4 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization
McGurk, L., Gomes, E., Guo, L., Mojsilovic-Petrovic, J., Tran, V., Kalb, R. G., Shorter, J. & Bonini, N. M., 6 Sep 2018, In: Molecular Cell. 71, 5, p. 703-717.e9 24 p.Research output: Contribution to journal › Article › peer-review
94 Citations (Scopus) -
2015
Drosophila as an in vivo model for human neurodegenerative disease
McGurk, L., Berson, A. & Bonini, N. M., Oct 2015, In: Genetics. 201, 2, p. 377-402 26 p.Research output: Contribution to journal › Article › peer-review
122 Citations (Scopus) -
2011
Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: Loss of ADAR1 in insects
Keegan, L. P., McGurk, L., Palavicini, J. P., Brindle, J., Paro, S., Li, X., Rosenthal, J. J. C. & O'Connell, M. A., 1 Sep 2011, In: Nucleic Acids Research. 39, 16, p. 7249-7262 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (Scopus)80 Downloads (Pure) -
Yeast informs Alzheimer's disease
McGurk, L. & Bonini, N. M., 2 Dec 2011, In: Science. 334, 6060, p. 1212-1213 2 p.Research output: Contribution to journal › Short survey › peer-review
7 Citations (Scopus)