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  • Angus Lamond
2016

Quantitative proteomic analysis of the human nucleolus

Bensaddek, D., Nicolas, A. & Lamond, A. I., 2016, The nucleolus: methods and protocols. Németh, A. (ed.). New York: Springer , p. 249-262 14 p. (Methods in molecular biology; vol. 1455).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

4 Citations (Scopus)
2011

Quantitative Proteomic Analysis of Chromatin Reveals that Ctf18 Acts in the DNA Replication Checkpoint

Kubota, T., Hiraga, S., Yamada, K., Lamond, A. I. & Donaldson, A. D., Jul 2011, In : Molecular & Cellular Proteomics. 10, 7, p. - 14 p., M110.005561. .

Research output: Contribution to journalArticle

43 Citations (Scopus)
2016

Analysis of mass spectrometry data for nucleolar proteomics experiments

Nicolas, A., Bensaddek, D. & Lamond, A. I., 2016, The nucleolus: methods and protocols. Németh, A. (ed.). New York: Springer , p. 263-276 14 p. (Methods in molecular biology; vol. 1455).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

2013

Modulation of higher order chromatin conformation in mammalian cell nuclei can be mediated by polyamines and divalent cations

Visvanathan, A., Ahmed, K., Even-Faitelson, L., Lleres, D., Bazett-Jones, D. P. & Lamond, A. I., 2013, In : PLoS ONE. 8, 6, 16 p., e67689.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2019

Signal enhanced proteomics: a biological perspective on dissecting the functional organisation of cell proteomes

Bensaddek, D., Nicolas, A. & Lamond, A. I., Feb 2019, In : Current Opinion in Chemical Biology. 48, p. 114-122 9 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2012

Advancing cell biology through proteomics in space and time (PROSPECTS)

Lamond, A. I., Uhlen, M., Horning, S., Makarov, A., Robinson, C. V., Serrano, L., Hartl, F. U., Baumeister, W., Werenskiold, A. K., Andersen, J. S., Vorm, O., Linial, M., Aebersold, R. & Mann, M., 1 Mar 2012, In : Molecular & Cellular Proteomics. 11, 3

Research output: Contribution to journalArticle

50 Citations (Scopus)
2013

Analysis of human protein replacement stable cell lines established using snoMEN-PR vector

Ono, M., Yamada, K., Endo, A., Avolio, F. & Lamond, A. I., 25 Apr 2013, In : PLoS ONE. 8, 4, 12 p., e62305.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
114 Downloads (Pure)
2017

The chromatin assembly factor complex 1 (CAF1) and 5-Azacytidine (5-AzaC) affect cell motility in Src-transformed human epithelial cells

Endo, A., Ly, T., Pippa, R., Bensaddek, D., Nicolas, A. & Lamond, A. I., 6 Jan 2017, In : Journal of Biological Chemistry. 292, 1, p. 172-184 13 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
195 Downloads (Pure)
2016

Unlocking the chromatin code by deciphering protein–DNA interactions

Bensaddek, D. & Lamond, A., Nov 2016, In : Molecular Systems Biology. 12, 11, p. 1-3 3 p., 887.

Research output: Contribution to journalArticle

Open Access
File
184 Downloads (Pure)
2019

The Encyclopedia of Proteome Dynamics: The KinoViewer

Brenes Murillo, A. & Lamond, A., 15 Apr 2019, In : Bioinformatics. 35, 8, p. 1441-1442 2 p., bty823.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
93 Downloads (Pure)
2014

FMDV replicons encoding green fluorescent protein are replication competent

Tulloch, F., Pathania, U., Luke, G. A., Nicholson, J., Stonehouse, N. J., Rowlands, D. J., Jackson, T., Tuthill, T., Haas, J., Lamond, A. I. & Ryan, M. D., 1 Dec 2014, In : Journal of Virological Methods. 209, p. 35-40 6 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
125 Downloads (Pure)
2011

Quantitative Proteomics and Dynamic Imaging of the Nucleolus Reveal Distinct Responses to UV and Ionizing Radiation

Moore, H. M., Bai, B., Boisvert, F-M., Latonen, L., Rantanen, V., Simpson, J. C., Pepperkok, R., Lamond, A. I. & Laiho, M., Oct 2011, In : Molecular & Cellular Proteomics. 10, 10, p. - 15 p., M111.009241.

Research output: Contribution to journalArticle

78 Citations (Scopus)
2017

Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans

Harvald, E. B., Sprenger, R. R., Dall, K. B., Ejsing, C. S., Nielsen, R., Mandrup, S., Brenes Murillo, A., Larance, M., Gartner, A., Lamond, A. & Færgeman, N. J., 26 Jul 2017, In : Cell Systems. 5, 1, p. 38-52.e4 13 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
211 Downloads (Pure)
2020

Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes

McCarthy, D. J., Rostom, R., Huang, Y., Kunz, D. J., Danecek, P., Bonder, M. J., Hagai, T., Lyu, R., Wang, W., Gaffney, D. J., Simons, B. D., Stegle, O. & Teichmann, S. A., 16 Mar 2020, In : Nature Methods. 17, 4, p. 414-421 8 p.

Research output: Contribution to journalArticle

2013

RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans

Akay, A., Craig, A., Lehrbach, N., Larance, M., Pourkarimi, E., Wright, J. E., Lamond, A., Miska, E. & Gartner, A., Nov 2013, In : Open Biology. 3, 130151.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2014

A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II

Hutten, S., Chachami, G., Winter, U., Melchior, F. & Lamond, A. I., 1 Mar 2014, In : Journal of Cell Science. 127, 5, p. 1065-1078 14 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
209 Downloads (Pure)

A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells

Ly, T., Ahmad, Y., Shlien, A., Soroka, D., Mills, A., Emanuele, M. J., Stratton, M. R. & Lamond, A. I., 4 Mar 2014, In : eLife. 2014, 3, e01630.

Research output: Contribution to journalArticle

Open Access
File
72 Citations (Scopus)
114 Downloads (Pure)
2011

Stable-isotope labeling with amino acids in nematodes

Larance, M., Bailly, A. P., Pourkarimi, E., Hay, R. T., Buchanan, G., Coulthurst, S., Xirodimas, D. P., Gartner, A. & Lamond, A. I., Oct 2011, In : Nature Methods. 8, 10, p. 849-851 3 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)
2013

Plant SILAC: stable-isotope labelling with amino acids of Arabidopsis seedlings for quantitative proteomics

Lewandowska, D., ten Have, S., Hodge, K., Tillemans, V., Lamond, A. I. & Brown, J. W. S., 20 Aug 2013, In : PLoS ONE. 8, 8, e72207.

Research output: Contribution to journalArticle

23 Citations (Scopus)

PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192

Moser, S. C., Bensaddek, D., Ortmann, B., Maure, J-F., Mudie, S., Blow, J. J., Lamond, A. I., Swedlow, J. R. & Rocha, S., 26 Aug 2013, In : Developmental Cell. 26, 4, p. 381-392 12 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2018

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

Loftus, R. M., Assmann, N., Kedia-Mehta, N., O'Brien, K. L., Garcia, A., Gillespie, C., Hukelmann, J. L., Oefner, P. J., Lamond, A. I., Gardiner, C. M., Dettmer, K., Cantrell, D. A., Sinclair, L. V. & Finlay, D. K., 14 Jun 2018, In : Nature Communications. 9, 1, p. 1-15 15 p., 2341.

Research output: Contribution to journalArticle

Open Access
File
40 Citations (Scopus)
147 Downloads (Pure)
2015

Identification of small molecule inhibitors of pre-mRNA splicing

Pawallek, A., McElroy, S., Samatov, T., Mitchell, L., Woodland, A., Ryder, U., Gray, D., Lührmann, R. & Lamond, A. I., 6 Mar 2015, In : Journal of Biological Chemistry. 290, 10, 1 p.

Research output: Contribution to journalComment/debate

Open Access
2 Citations (Scopus)
2018

The Encyclopedia of Proteome Dynamics – A big data ecosystem for (prote)omics

Brenes Murillo, A., Afzal, V., Kent, R. & Lamond, A., 4 Jan 2018, In : Nucleic Acids Research. 46, D1, p. D1202-D1209 8 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
149 Downloads (Pure)
2016

The histone chaperone Vps75 forms multiple oligomeric assemblies capable of mediating exchange between histone H3–H4 tetramers and Asf1–H3–H4 complexes

Hammond, C. M., Sundaramoorthy, R., Larance, M., Lamond, A., Stevens, M. A., El-Mkami, H., Norman, D. & Owen-Hughes, T., 27 Jul 2016, In : Nucleic Acids Research. 44, 13, p. 6157-6172 16 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
250 Downloads (Pure)
2019

Functional and proteomic analysis of a full thickness filaggrin-deficient skin organoid model

Elias, M. S., Wright, S. C., Nicholson, W. V., Morrison, K. D., Prescott, A. R., Ten Have, S., Whitfield, P. D., Lamond, A. I. & Brown, S. J., 9 Sep 2019, In : Wellcome Open Research. 4, p. 134 28 p.

Research output: Contribution to journalArticle

Open Access
File
61 Downloads (Pure)
2018

Proteomic analysis of the cell cycle of procylic form Trypanosoma brucei

Crozier, T. W. M., Tinti, M., Wheeler, R. J., Ly, T., Ferguson, M. A. J. & Lamond, A. I., 1 Jun 2018, In : Molecular & Cellular Proteomics. 17, 6, p. 1184-1195 12 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
138 Downloads (Pure)
2017

Common genetic variation drives molecular heterogeneity in human iPSCs

Kilpinen, H., Goncalves, A., Leha, A., Afzal, V., Alasoo, K., Ashford, S., Bala, S., Bensaddek, D., Casale, F. P., Culley, O. J., Danecek, P., Faulconbridge, A., Harrison, P. W., Kathuria, A., McCarthy, D. J., McCarthy, S. A., Meleckyte, R., Memari, Y., Moens, N., Soares, F. & 23 others, Mann, A., Streeter, I., Agu, C. A., Alderton, A., Nelson, R., Harper, S., Patel, M., White, A., Patel, S. R., Clarke, L., Halai, R., Kirton, C. M., Kolb-Kokocinski, A., Beales, P. L., Birney, E., Danovi, D., Lamond, A. I., Ouwehand, W. H., Vallier, L., Watt, F. M., Durbin, R., Stegle, O. & Gaffney, D. J., 15 Jun 2017, In : Nature. 546, 7658, p. 370-375 6 p.

Research output: Contribution to journalArticle

Open Access
File
137 Citations (Scopus)
151 Downloads (Pure)
2015

Multidimentional proteomics for cell biology

Larance, M. & Lamond, A. I., May 2015, In : Nature Reviews Molecular Cell Biology. 16, 5, p. 269-280 12 p.

Research output: Contribution to journalArticle

Open Access
File
206 Citations (Scopus)
282 Downloads (Pure)
2013

Global subcellular characterization of protein degradation using quantitative proteomics

Larance, M., Ahmad, Y., Kirkwood, K. J., Ly, T. & Lamond, A. I., Mar 2013, In : Molecular & Cellular Proteomics. 12, 3, p. 638-650 13 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)
2017

Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs (Nature (2017) 546 (370-375) DOI: 10.1038/nature22403)

Kilpinen, H., Goncalves, A., Leha, A., Afzal, V., Alasoo, K., Ashford, S., Bala, S., Bensaddek, D., Casale, F. P., Culley, O. J., Danecek, P., Faulconbridge, A., Harrison, P. W., Kathuria, A., McCarthy, D. J., McCarthy, S. A., Meleckyte, R., Memari, Y., Moens, N., Soares, F. & 23 others, Mann, A., Streeter, I., Agu, C. A., Alderton, A., Nelson, R., Harper, S., Patel, M., White, A., Patel, S. R., Clarke, L., Halai, R., Kirton, C. M., Kolb-Kokocinski, A., Beales, P. L., Birney, E., Danovi, D., Lamond, A., Ouwehand, W. H., Vallier, L., Watt, F. M., Durbin, R., Stegle, O. & Gaffney, D. J., 29 Jun 2017, In : Nature. 546, 7660, p. 686 1 p.

Research output: Contribution to journalComment/debate

6 Citations (Scopus)
2013

Identification and functional characterization of FMN2: a regulator of the cyclin-dependent kinase Inhibitor p21

Yamada, K., Ono, M., Perkins, N. D., Rocha, S. & Lamond, A. I., Mar 2013, In : Molecular Cell. 49, 5, p. 922-933 12 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2012

Inhibition of Pre-mRNA Splicing by a Synthetic Blom7α-Interacting Small RNA

Löscher, M., Schosserer, M., Dausse, E., Lee, K., Ajuh, P. M., Grillari-Voglauer, R., Lamond, A. I., Toulmé, J. J. & Grillari, J., 29 Oct 2012, In : PLoS ONE. 7, 10, 9 p., e47497.

Research output: Contribution to journalArticle

Open Access
2013

FMN2 is a novel regulator of the cyclin-dependent kinase inhibitor p21

Yamada, K., Ono, M., Bensaddek, D., Lamond, A. I. & Rocha, S., 1 Aug 2013, In : Cell cycle (Georgetown, Tex.). 12, 15, p. 2348-2354 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Cleaning up the masses: Exclusion lists to reduce contamination with HPLC-MS/MS

Hodge, K., Ten Have, S., Hutton, L. & Lamond, A. I., 2 Aug 2013, In : Journal of Proteomics. 88, p. 92-103 12 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2011

The Nucleolus

Hutten, S., Westman, B. J., Boisvert, F. M., van Koningsbruggen, V. K. & Lamond, A. I., 14 Nov 2011, Genome Organization and Function in the Cell Nucleus. Weinheim: Wiley-VCH , p. 279-307 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)
2012

Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization

Ahmad, Y., Boisvert, F-M., Lundberg, E., Uhlen, M. & Lamond, A. I., 1 Mar 2012, In : Molecular & Cellular Proteomics. 11, 3

Research output: Contribution to journalArticle

37 Citations (Scopus)
2011

Exo70, a subunit of the exocyst complex, interacts with SNEVhPrp19/hPso4 and is involved in pre-mRNA splicing

Dellago, H., Löscher, M., Ajuh, P., Ryder, U., Kaisermayer, C., Grillari-Voglauer, R., Fortschegger, K., Gross, S., Gstraunthaler, A., Borth, N., Eisenhaber, F., Lamond, A. I. & Grillari, J., 15 Aug 2011, In : Biochemical Journal. 438, p. 81-91 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2016

Enhanced snoMEN Vectors Facilitate Establishment of GFP–HIF-1α Protein Replacement Human Cell Lines

Ono, M., Ono, K., Bensaddek, D., Afzal, V., Biddlestone, J., Ortmann, B., Mudie, S., Boivin, V., S. Scott, M., Rocha, S. & Lamond, A. I., 29 Apr 2016, In : PLoS ONE. 11, 4, 28 p., e0154759.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
179 Downloads (Pure)
2012

Perturbation of Chromatin Structure Globally Affects Localization and Recruitment of Splicing Factors

Schor, I. E., Llères, D., Risso, G. J., Pawellek, A., Ule, J., Lamond, A. I. & Kornblihtt, A. R., 12 Nov 2012, In : PLoS ONE. 7, 11, 16 p., e48084.

Research output: Contribution to journalArticle

Open Access
File
39 Citations (Scopus)
129 Downloads (Pure)
2016

Micro-proteomics with iterative data analysis: proteome analysis in C.elegans at the single worm level

Bensaddek, D., Narayan, V., Nicolas, A., Brenes Murillo, A., Gartner, A., Kenyon, C. & Lamond, A., 10 Feb 2016, In : Proteomics. 16, 3, p. 381-392

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
133 Downloads (Pure)
2020

Phosphoproteomics identifies a bimodal EPHA2 receptor switch that promotes embryonic stem cell differentiation

Fernandez-Alonso, R., Bustos, F., Budzyk, M., Kumar, P., Helbig, A. O., Hukelmann, J., Lamond, A. I., Lanner, F., Zhou, H., Petsalaki, E. & Findlay, G. M., 13 Mar 2020, In : Nature Communications. 11, 13 p., 1357.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
25 Downloads (Pure)
2012

The adenomatous polyposis Coli protein contributes to normal compaction of mitotic chromatin

Dikovskaya, D., Khoudoli, G., Newton, I. P., Chadha, G. S., Klotz, D., Visvanathan, A., Lamond, A., Swedlow, J. R. & Nathke, I. S., 2012, In : PLoS ONE. 7, 6, e38102.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2018

PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28γ

Jonik-Nowak, B., Menneteau, T., Fesquet, D., Baldin, V., Bonne-Andrea, C., Méchali, F., Fabre, B., Boisguerin, P., de Rossi, S., Henriquet, C., Pugnière, M., Ducoux-Petit, M., Burlet-Schiltz, O., Lamond, A., Fort, P., Boulon, S., Bousquet, M-P. & Coux, O., 10 Jul 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 28, p. E6477-E6486 10 p., 201722299.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
187 Downloads (Pure)
2017

Characterisation of the biflavonoid hinokiflavone as a premRNA splicing modulator that inhibits SENP

Pawellek, A., Ryder, U., Tammsalu, T., King, L. J., Kreinin, H., Ly, T., Hay, R. T., Hartley, R. & Lamond, A., 8 Sep 2017, In : eLife. 6, e27402.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
152 Downloads (Pure)
Open Access
File
5 Citations (Scopus)
169 Downloads (Pure)
2018
File
3 Citations (Scopus)
129 Downloads (Pure)
2017

Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation

Hiraga, S., Ly, T., Garzón, J., Hořejší, Z., Ohkubo, Y., Endo, A., Obuse, C., Boulton, S. J., Lamond, A. & Donaldson, A. D., 1 Mar 2017, In : EMBO Reports. 18, 3, p. 403-419 17 p.

Research output: Contribution to journalArticle

Open Access
File
44 Citations (Scopus)
130 Downloads (Pure)
Open Access
File
6 Citations (Scopus)
178 Downloads (Pure)
2016

The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway

Bailly, A., Perrin, A., Bou Malhab, L. J., Pion, E., Larance, M., Nagala, M., Smith, P., O'Donohue, M-F., Gleizes, P-E., Zomerdijk, J., Lamond, A. I. & Xirodimas, D. P., 28 Jan 2016, In : Oncogene. 35, 4, p. 415-426 12 p.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
306 Downloads (Pure)
2018

Efficient Analysis of Mammalian Polysomes in cells and tissues using Ribo Mega-SEC

Yoshikawa, H., Larance, M., Harney, D. J., Sundaramoorthy, R., Ly, T., Owen-Hughes, T. & Lamond, A. I., 10 Aug 2018, In : eLife. 7, 7, p. 1-26 26 p., e36530.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
133 Downloads (Pure)