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Author

  • Thomas MacDonald
2012

A pilot study to investigate the supply of investigational medicinal product to patients via mail in a streamlined safety study

Flynn, R. W., Saywood, W., Mackenzie, I. S., Wei, L. & MacDonald, T. M., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement S3, p. 124-125 2 p., 264.

Research output: Contribution to journalMeeting abstract

2019

Cardiovascular Safety of Prucalopride in Patients with Chronic Constipation: A Multinational Population-Based Cohort Study

Gilsenan, A., Fortuny, J., Cainzos-Achirica, M., Cantero, O. F., Flynn, R. W. V., Garcia-Rodriguez, L., Harding, A., Kollhorst, B., Karlsson, P., Linnér, L., MacDonald, T. M., Odsbu, I., Plana, E., Ruigómez, A., Schink, T., Ziemiecki, R. & Andrews, E. B., Oct 2019, In : Drug Safety. 42, 10, p. 1179-1190 12 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
70 Downloads (Pure)
2012

Effectiveness of statins in chronic kidney disease

Sheng, X., Macdonald, T. M., Wei, L. & Murphy, M. J., Jul 2012, In : QJM : an International Journal of Medicine. 105, 7, p. 641-648 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Spironolactone and the risk of breast cancer: a cohort study

Mackenzie, I. S., MacDonald, T. M., Thompson, A. M., Morant, S. & Wei, L., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement s3, p. 258-258 1 p., 550.

Research output: Contribution to journalMeeting abstract

51 Citations (Scopus)
2011

Hypertriglyceridemia and acute pancreatitis

Murphy, M. J., Sheng, X., MacDonald, T. M. & Wei, L., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, S1, p. S257-S257 1 p., 590.

Research output: Contribution to journalSpecial issue

6 Citations (Scopus)

Pilot Swine Flu Vaccination Active Surveillance Study: Final Results

Layton, D., Dryburgh, M., MacDonald, T. M., Shakir, S. A. & Mackenzie, I. S., 2011, In : Drug Safety. 34, 10, p. 889-890 2 p.

Research output: Contribution to journalBook/Film/Article review

2014

The authors reply

Wei, L., Macdonald, T. M. & Murphy, M. J., Jan 2014, In : Kidney International. 85, 1, p. 211 1 p.

Research output: Contribution to journalLetter

2011

Randomized Policy Trials: A Powerful Tool for Drug Safety and Effectiveness

Mackenzie, I. S., Wei, L., Paterson, K. & MacDonald, T. M., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, s1, p. S313-S313 1 p.

Research output: Contribution to journalBook/Film/Article review

2015
7 Citations (Scopus)
2011

Hypertension in octogenarians: treatment strategies and challenges

Mackenzie, I. S. & MacDonald, T. M., 1 Jan 2011, In : European Cardiology. 7, 1, p. 25-28 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Co-prescription of co-trimoxazole and spironolactone in elderly patients

Wei, L., MacDonald, T. M. & Mackenzie, I. S., 12 Sep 2011, In : BMJ. 343, 7823, p. - 2 p., d5656.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

Successful recruitment to a large online randomised trial: the TIME study

Rogers, A., Mackenzie, I., Rorie, D. & MacDonald, T., 2 May 2017, Trials: Meeting abstracts from the 4th International Clinical Trials Methodology Conference (ICTMC) and the 38th Annual Meeting of the Society for Clinical Trials. Supplement 1 ed. United Kingdom: BioMed Central, Vol. 18. p. 222-223 2 p. 089. (Trials; vol. 18, no. Suppl. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
595 Downloads (Pure)
2011

A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism

Parthasarathy, H. K., Menard, J., White, W. B., Young, W. F., Williams, G. H., Williams, B., Miguel Ruilope, L., McInnes, G. T., Connell, J. M. & MacDonald, T. M., May 2011, In : Journal of Hypertension. 29, 5, p. 980-990 11 p.

Research output: Contribution to journalArticle

135 Citations (Scopus)
2014

Effectiveness of newspaper advertising for patient recruitment into a clinical trial

Hapca, A., Jennings, C. G., Wei, L., Wilson, A., MacDonald, T. M. & Mackenzie, I. S., Jun 2014, In : British Journal of Clinical Pharmacology. 77, 6, p. 1064-1072 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2018

AB1029 Allopurinol and cardiovascular outcomes in patients with ischaemic heart disease (ALL-HEART) study: baseline characteristics of the randomised patient population

Mackenzie, I., Ford, I., Hawkey, C., Begg, A., Taggar, J., Struthers, A., Wei, L., Avery, A., Walker, A., Duce, S., Barr, R., Dumbleton, J. & Macdonald, T., 12 Jun 2018, In : Annals of the Rheumatic Diseases. 77, suppl. 2, p. 1631.1-1631 1 p.

Research output: Contribution to journalConference article

2012
28 Citations (Scopus)
2019

Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study

Wei, L., Lai, E. C-C., Kao-Yang, Y-H., Walker, B. R., MacDonald, T. M. & Andrew, R., 10 Apr 2019, In : BMJ (Clinical research ed.). 365, p. 1-11 11 p., l1204.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
124 Downloads (Pure)

Allopurinol treatment adversely impacts left ventricular mass regression in patients with well-controlled hypertension

Gingles, C., Symon, R., Gandy, S., Struthers, A., Houston, G., MacDonald, T., Lang, C., Donnan, P. & George, J., Dec 2019, In : Journal of Hypertension. 37, 12, p. 2481-2489 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
144 Downloads (Pure)
2013

Pioglitazone and bladder cancer: A propensity score matched cohort study

Wei, L., Macdonald, T. M. & Mackenzie, I. S., Jan 2013, In : British Journal of Clinical Pharmacology. 75, 1, p. 254-259 6 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)
2016

Treatment in the Morning versus Evening (TIME) Study: Feasibility of an Online Study

Rorie, D. A., Rogers, A., Mackenzie, I. S., Findlay, E., MacDonald, T. M., Ford, I., Webb, D. J., Williams, B., Brown, M. & Poulter, N. R., 21 Sep 2016, In : Journal of Clinical Trials. 6, 5, p. 1-7 7 p., 1000281.

Research output: Contribution to journalArticle

Open Access
File
120 Downloads (Pure)
2017

Spironolactone use and risk of incident cancers: a retrospective, matched cohort study

Mackenzie, I. S., Morant, S. V., Wei, L., Thompson, A. M. & MacDonald, T. M., 14 Feb 2017, In : British Journal of Clinical Pharmacology. 83, 3, p. 653-663 11 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
168 Downloads (Pure)
2011
6 Citations (Scopus)
2016

Methods of a large prospective, randomised, open-label, blinded end-point study comparing morning versus evening dosing in hypertensive patients: the Treatment In Morning versus Evening (TIME) study

Rorie, D. A., Rogers, A., Mackenzie, I. S., Ford, I., Webb, D. J., Willams, B., Brown, M., Poulter, N., Findlay, E., Saywood, W. & MacDonald, T. M., 9 Feb 2016, In : BMJ Open. 6, 2, e010313.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
143 Downloads (Pure)
2020
Open Access
File
16 Downloads (Pure)
2018
Open Access
File
125 Downloads (Pure)
2014
39 Citations (Scopus)
2013

Changing face of multiple sclerosis in the United kingdom 1990-2010: an incidence and prevalence study

Mackenzie, I. S., Morant, S. V., Bloomfield, G. A., Macdonald, T. M. & O'Riordan, J. I., Nov 2013, In : Journal of Neurology, Neurosurgery and Psychiatry. 84, 11, 1 p., ABN Abstracts 027.

Research output: Contribution to journalMeeting abstract

2012

Association between appendicectomy in females and subsequent pregnancy rate: a cohort study

Wei, L., MacDonald, T. & Shimi, S., Aug 2012, In : Fertility and Sterility. 98, 2, p. 401-405 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2015
1 Citation (Scopus)
2017

Acid-suppression medications and bacterial gastroenteritis: a population-based cohort study

Wei, L., Ratnayake, L., Phillips, G., McGuigan, C. C., Morant, S. V., Flynn, R. W., Mackenzie, I. S. & MacDonald, T. M., Jun 2017, In : British Journal of Clinical Pharmacology. 83, 6, p. 1298-1308 11 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
179 Downloads (Pure)
2019
Open Access
File
112 Downloads (Pure)
2016

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

Brown, M. J., Williams, B., Morant, S. V., Webb, D. J., Caulfield, M. J., Cruickshank, J. K., Ford, I., McInnes, G., Sever, P., Salsbury, J., Mackenzie, I. S., Padmanabhan, S., MacDonald, T. M. & for the British Hypertension Society's Prevention, Treatment of Hypertension with Algorithm-based Therapy (PATHWAY) Studies Group, Feb 2016, In : The Lancet: Diabetes and Endocrinology. 4, 2, p. 136-147 12 p.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
140 Downloads (Pure)
2011
6 Citations (Scopus)
2015

Does offering an incentive payment improve recruitment to clinical trials and increase the proportion of socially deprived and elderly participants?

Jennings, C. G., MacDonald, T. M., Wei, L., Brown, M. J., McConnachie, L. & Mackenzie, I. S., 7 Mar 2015, In : Trials. 16, 9 p., 80.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
124 Downloads (Pure)
2016

PATHWAY-2: Spironolactone for resistant hypertension - Authors' reply

Williams, B., MacDonald, T. M., Morant, S. V. & Brown, M. J., 2 Apr 2016, In : Lancet. 387, 10026, p. 1373-1374 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)
2012

Navigating the shoals in hypertension: discovery and guidance

Brown, M. J., Cruickshank, J. K. & MacDonald, T. M., 28 Jan 2012, In : BMJ. 344, 7841, p. d8218

Research output: Contribution to journalArticle

16 Citations (Scopus)
2017

The British Society for Rheumatology Guideline for the Management of Gout

Hui, M., Carr, A., Cameron, S., Davenport, G., Doherty, M., Forrester, H., Jenkins, W., Jordan, K. M., Mallen, C. D., MacDonald, T., Nuki, G., Pywell, A., Zhang, W. & Roddy, E., Jul 2017, In : Rheumatology. 56, 7, p. 1056-1059 4 p.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
155 Downloads (Pure)

Investigating Real-World Clopidogrel Pharmacogenetics in Stroke Using a Bioresource Linked to Electronic Medical Records

Tornio, A., Flynn, R., Morant, S., Velten, E., Palmer, C. N. A., MacDonald, T. M. & Doney, A. S. F., 1 Feb 2018, In : Clinical Pharmacology & Therapeutics. 103, 2, p. 281-286 6 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
161 Downloads (Pure)
Open Access
File
19 Downloads (Pure)
2013

Association between cardiovascular events and sodium-containing effervescent, dispersible, and soluble drugs: nested case-control study

George, J., Majeed, W., Mackenzie, I. S., MacDonald, T. M. & Wei, L., 26 Nov 2013, In : BMJ. 347, f6954.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2011

The appropriate use of non-steroidal anti-inflammatory drugs in rheumatic disease: opinions of a multidisciplinary European expert panel

Burmester, G., Lanas, A., Biasucci, L., Hermann, M., Lohmander, S., Olivieri, I., Scarpignato, C., Smolen, J., Hawkey, C., Bajkowski, A., Berenbaum, F., Breedveld, F., Dieleman, P., Dougados, M., MacDonald, T., Martin Mola, E., Mets, T., Van den Noortgate, N. & Stoevelaar, H., May 2011, In : Annals of the Rheumatic Diseases. 70, 5, p. 818-822 5 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)
2012

An audit of the diagnostic coding of pancreatitis of 331 patients in Tayside, Scotland

Ghorbanifard, Z., Daryabakhsh, A. S., Wei, L., Murphy, M. J. & MacDonald, T. M., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement s3, p. 398-398 1 p., 859.

Research output: Contribution to journalMeeting abstract

2011

Cardiovascular Safety of Lumiracoxib: A Meta-Analysis of Randomised Controlled Trials in Patients with Osteoarthritis

Mackenzie, I. S., Wei, L. & MacDonald, T. M., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, s1, p. S354-S354 1 p.

Research output: Contribution to journalBook/Film/Article review

6 Citations (Scopus)

Can microalbuminuria identify silent "pancardiac" target organ damage in a non-diabetic primary prevention population?

Nadir, A., Rekhraj, S., Davidson, J., MacDonald, T. M., Lang, C. & Struthers, A. D., Jun 2011, In : Heart. 97, p. A35-A35 1 p.

Research output: Contribution to journalBook/Film/Article review

2017

Study protocol for statin web-based investigation of side effects (StatinWISE): a series of randomised controlled N-of-1 trials comparing atorvastatin and placebo in UK primary care

Herrett, E., Williamson, E., Beaumont, D., Prowse, D., Youssouf, N., Brack, K., Armitage, J., Goldacre, B., MacDonald, T., Staa, T. V., Roberts, I., Shakur-Still, H. & Smeeth, L., 1 Dec 2017, In : BMJ Open. 7, 12, p. 1-8 8 p., e016604.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
124 Downloads (Pure)
2019

Study Design and Cohort Comparability in a Study of Major Cardiovascular Events in New Users of Prucalopride Versus Polyethylene Glycol 3350

Fortuny, J., Gilsenan, A., Cainzos-Achirica, M., Cantero, O. F., Flynn, R. W. V., Garcia-Rodriguez, L., Kollhorst, B., Karlsson, P., Linnér, L., MacDonald, T. M., Plana, E., Ruigómez, A., Schink, T., Ziemiecki, R. & Andrews, E. B., Oct 2019, In : Drug Safety. 42, 10, p. 1167-1177 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
118 Downloads (Pure)
2012
3 Citations (Scopus)