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  • Chim Lang
2011

Isolated large vessel pulmonary vasculitis as a cause of chronic obstruction of the pulmonary arteries

Hagan, G., Gopalan, D., Church, C., Rassl, D., Mukhtyar, C., Wistow, T., Lang, C., Sivasothy, P., Stewart, S., Jayne, D., Shearer, K., Tsui, S., Jenkins, D. P. & Pepke-Zaba, J., 2011, In : Pulmonary Circulation. 1, 3, p. 425-429 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2020

Distinct Pathological Pathways in Patients with Heart Failure and Diabetes

Tromp, J., Voors, A. A., Sharma, A., Ferreira, J. P., Ouwerkerk, W., Hillege, H. L., Arevalo Gomez, K., Dickstein, K., Anker, S. D., Metra, M., Lang, C., Ng, L. L., van der Harst, P., van Veldhuisen, D. J., van der Meer, P., Lam, C. S. P., Zannad, F. & Sama, I. E., Mar 2020, In : JACC: Heart Failure. 8, 3, p. 234-242 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2011
2014

Myocardial ischaemia is associated with an elevated brain natriuretic pepide level even in the presence of left ventricular systolic dysfunction

Nadir, M. A., Dow, E., Davidson, J., Kennedy, N., Lang, C. C. & Struthers, A. D., 2 Jan 2014, In : European Journal of Heart Failure. 16, 1, p. 56-67 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2011

Angiotensin-converting enzyme inhibitors in patients with aortic stenosis and their impact on survival

Nadir, M. A., Libianto, R., Elder, D., Wei, L., Lim, T., Pringle, S. D., Doney, A., Struthers, A. D., Pauriah, M., Choy, A. & Lang, C. C., Feb 2011, In : Scottish Medical Journal. 56, 1, p. 54-55 2 p.

Research output: Contribution to journalBook/Film/Article review

2014

The impact of age and chronic kidney disease on secondary prevention post-primary percutaneous coronary intervention

Zachariah, D., Brown, R., Kanagala, P., Bashir, A., Mohan, M., Callan, P., Rajendra, R., Clark, A. L., Squire, I., Gunning, M., Lang, C. C. & Kalra, P. R., Mar 2014, In : QJM : an International Journal of Medicine. 107, 3, p. 185-192

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Cardiac rehabilitation in heart failure with reduced ejection fraction: A "should take it and not leave it" intervention

Taylor, R., Dalal, H., Davies, R., Doherty, P., Jolly, K., Lang, C. & Wingham, J., Oct 2017, In : American Heart Journal. 192, p. e1-e2 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)
2014
5 Citations (Scopus)
2013
3 Citations (Scopus)
2012

The prognostic value of a 7-week high sensitivity troponin T level after an acute coronary syndrome

Ang, D. S. C., Kao, M. P. C., Dow, E., Lang, C. & Struthers, A., 2012, In : Heart. 98, 15, p. 1160-5 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2011

Right ventricular pacing impairs endothelial function in man

Choy, A. M., Su, H. H. M., Elder, D. H. J., Noman, A., Pauriah, M., Struthers, A. D. & Lang, C. C., Jun 2011, In : EP-Europace. 13, 6, p. 853-858 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

A systems BIOlogy Study to TAilored Treatment in Chronic Heart Failure: Rationale, design, and baseline characteristics of BIOSTAT-CHF

Voors, A. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., ter Maaten, J. M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H. & Metra, M., 20 Jun 2016, In : European Journal of Heart Failure. 18, 6, p. 716-726 11 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)
2018

The novel biomarker plasma desmosine, a marker of elastin breakdown, is an independent predictor of abdominal aortic aneurysm events independent of aneurysm size

Mordi, I., Forsythe, R., Bown, M., Lang, C., Newby, D. E., Gellatly, C., Chin, C. W. L., McBride, O., Saratzis, A., Iskandar, Z., Chalmers, R., Huang, J. & Choy, A., Aug 2018, In : European Heart Journal. 39, Suppl 1, p. 1253-1254 ehy566.P6040.

Research output: Contribution to journalMeeting abstract

2019

Urinary desmosine, a biomarker of elastin degradation is significantly elevated and associated with maximum aortic root size and aortic Z-scores in patients with bicuspid aortic valve

Iskandar, Z., Huang, J., Miller, L., Chin, C., Mordi, I., Mcwilliam, C., Goudie, D., Berg, J., Neagoie, A., Lang, C. & Choy, A-M., 26 May 2019, In : Heart. 105, Supplement 6, p. A103-A104 2 p., 126.

Research output: Contribution to journalMeeting abstract

2018

65 The novel plasma biomarker desmosine, a marker of elastin breakdown, is an independent predictor of abdominal aortic aneurysm events independent of aneurysm size

Mordi, I., Forsythe, R., Bown, M., Lang, C., Newby, D. E., Gellatly, C., Chin, C. W. L., McBride, O., Saratzis, A., Iskandar, Z., Chalmers, R., Huang, J. & Choy, A., Jun 2018, In : Heart. 104, Suppl 6, p. A58-59 2 p.

Research output: Contribution to journalMeeting abstract

4 Citations (Scopus)
2011

Allopurinol Benefits Left Ventricular Mass and Endothelial Dysfunction in Chronic Kidney Disease

Kao, M. P., Ang, D. S., Gandy, S. J., Nadir, M. A., Houston, J. G., Lang, C. C. & Struthers, A. D., Jul 2011, In : Journal of the American Society of Nephrology. 22, 7, p. 1382-1389 8 p.

Research output: Contribution to journalArticle

134 Citations (Scopus)
2013

Allopurinol reduces left ventricular mass in patients with type ii diabetes and left ventricular hypertrophy

Szwejkowski, B. R., Gandy, S., Rekhraj, S., Houston, G., George, J., Lang, C. C., Morris, A. D. & Struthers, A. D., 2013, In : Journal of the American College of Cardiology. 61, 10 Supplement, p. E1256 1 p.

Research output: Contribution to journalMeeting abstract

2019

The Role of Cathepsin D in the Pathophysiology of Heart Failure and its Potentially Beneficial Properties: a translational approach

Hoes, M. F., Tromp, J., Ouwerkerk, W., Bomer, N., Oberdorf-Maas, S. U., Samani, N. J., Ng, L. L., Lang, C., van der Harst, P., Hillege, H. L., Anker, S. D., Metra, M., van Veldhuisen, D. J., Voors, A. A. & van der Meer, P., 3 Dec 2019, In : European Journal of Heart Failure. 10 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
53 Downloads (Pure)

Metformin and its Potential for Heart Failure with Preserved Ejection Fraction

Mohan, P., Iskandar, Z., Mordi, I., Yeow, C., Neaogoie, A., Rena, G., Chew, S. & Lang, C., 26 Aug 2019, In : Journal of Diabetes and Treatment. 4, 2, 4 p.

Research output: Contribution to journalEditorial

Open Access
File
79 Downloads (Pure)

The Clinical Significance of Interleukin-6 in Heart Failure: Results from the BIOSTAT-CHF Study

Markousis-Mavrogeni, G., Tromp, J., Ouwerkerk, W., Devalarja, M., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G. S., van der Harst, P., Lang, C., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., Zannad, F., Zwinderman, A. H., Hillege, H. L., van Veldhuisen, D. J., Kakkar, R., Voors, A. & 1 others, Meer, P. V. D., Aug 2019, In : European Journal of Heart Failure. 21, 8, p. 965-973 9 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
116 Downloads (Pure)
2012

High dose allopurinol reduces left ventricular hypertrophy and improves endothelial function in patients with chronic stable angina

Rekhraj, S., Szwejkowski, B., Nadir, A., Gandy, S., George, J., Lang, C. C. & Struthers, A. D., 1 Aug 2012, In : European Heart Journal. 33, S1, p. 350-350 1 p.

Research output: Contribution to journalMeeting abstract

4 Citations (Scopus)
2019

Allopurinol treatment adversely impacts left ventricular mass regression in patients with well-controlled hypertension

Gingles, C., Symon, R., Gandy, S., Struthers, A., Houston, G., MacDonald, T., Lang, C., Donnan, P. & George, J., Dec 2019, In : Journal of Hypertension. 37, 12, p. 2481-2489 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
141 Downloads (Pure)
2020

Reply

Gingles, C. R., Symon, R., Gandy, S. J., Struthers, A. D., Houston, G., MacDonald, T. M., Lang, C. C., Donnan, P. T. & George, J., 1 Jan 2020, In : Journal of Hypertension. 38, 1, p. 177-178 2 p.

Research output: Contribution to journalLetter

Reply: Cardiovascular Benefits of Switching from Tobacco to Electronic Cigarettes

George, J., Hussain, M., Struthers, A., Donnan, P., Lang, C. & Khan, F., 7 Apr 2020, In : Journal of the American College of Cardiology. 75, 13, p. 1613-1614 2 p.

Research output: Contribution to journalLetter

2011

Angiotensin converting enzyme inhibitor use is associated with reduced mortality in patients with aortic regurgitation

Elder, D., Szwejkowski, B. R., Nadir, A. M., Pauriah, M., Rekraj, S., Lim, T., George, J., Doney, A., Pringle, S. D., Choy, A. M., Struthers, A. D. & Lang, C. C., 5 Apr 2011, In : Journal of the American College of Cardiology. 57, 14 Supplement, p. E1307-E1307 1 p.

Research output: Contribution to journalBook/Film/Article review

2012

Pulmonary hypertension predicts all-cause mortality in patients with heart failure: a retrospective cohort study

Szwejkowski, B. R., Elder, D. H. J., Shearer, F., Jack, D., Choy, A. M. J., Pringle, S. D., Struthers, A. D., George, J. & Lang, C. C., 2012, In : European Journal of Heart Failure. 14, 2, p. 162-167 6 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2019

The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure

Santema, B. T., Chan, M. M. Y., Tromp, J., Dokter, M., van der Wal, H., Emmens, J. E., Takens, J., Samani, N. J., Ng, L. L., Lang, C., van der Meer, P., ter Maaten, J. M., Damman, K., Dickstein, K., Cleland, J. G., Zannad, F., Anker, S. D., Metra, M., van der Harst, P., de Boer, R. A. & 4 others, van Veldhuisen, D. J., Rienstra, M., Lam, C. S. P. & Voors, A. A., 1 Jul 2019, In : Clinical Research in Cardiology . 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
77 Downloads (Pure)
2018

Biomarker-Guided Versus Guideline-Based Treatment of Patients With Heart Failure: Results From BIOSTAT-CHF

Ouwerkerk, W., Zwinderman, A. H., Ng, L. L., Demissei, B., Hillege, H. L., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., ter Maaten, J. M., Lang, C., van der Harst, P., Filippatos, G. S., Dickstein, K., Cleland, J. G. F., Anker, S. D. & Voors, A. A., 30 Jan 2018, In : Journal of the American College of Cardiology. 71, 4, p. 386-398 13 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
262 Downloads (Pure)
2020

Circulating plasma concentrations of ACE2 in men and women with heart failure and effects of renin-angiotensin-aldosterone-inhibitors

Sama, I. E., Ravera, A., Santema, B. T., van Goor, H., ter Maaten, J. M., Cleland, J. G. F., Rienstra, M., Friedrich, A. W., Samani, N. J., Ng, L. L., Dickstein, K., Lang, C. C., Filippatos, G., Anker, S. D., Ponikowski, P., Metra, M., van Veldhuisen, D. J. & Voors, A. A., 14 May 2020, In : European Heart Journal. 41, 19, p. 1810-1817 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2013

Is thiazolidinedione treatment an important cause of oedema?

Vella, S., Donnelly, L., Lang, C. C., Pearson, E. R. & Petrie, J. R., Mar 2013, In : Diabetic Medicine. 30, Suppl. 1, p. 197-197 1 p., P562.

Research output: Contribution to journalMeeting abstract

2020
Open Access
File
11 Downloads (Pure)
2018

Novel Endotypes in Heart Failure: Effects on Guideline-Directed Medical Therapy

Tromp, J., Ouwerkerk, W., Demissei, B., Anker, S. D., Cleland, J. G. F., Dickstein, K., Filippatos, G. S., van der Harst, P., Hillege, H. L., Lang, C. C., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Voors, A. A. & van der Meer, P., 21 Dec 2018, In : European Heart Journal. 39, 48, p. 4269-4276 8 p., ehy712.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
40 Downloads (Pure)

Comparing biomarker profiles of patients with heart failure: atrial fibrillation vs. sinus rhythm and reduced vs. preserved ejection fraction

Santema, B. T., Kloosterman, M., Van Gelder, I. C., Mordi, I., Lang, C., Lam, C. S. P., Anker, S. D., Cleland, J. G. F., Dickstein, K., Filippatos, G. S., van der Harst, P., Hillege, H. L., ter Maaten, J. M., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Zannad, F. & 4 others, Damman, K., van der Meer, P., Rienstra, M. & Voors, A. A., 14 Nov 2018, In : European Heart Journal. 39, 43, p. 3867-3875 9 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
63 Downloads (Pure)
2019

Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational cohort study

Santema, B. T., Ouwerkerk, W., Tromp, J., Sama, I. E., Ravera, A., Regitz-Zagrosek, V., Hillege, H., Samani, N. J., Zannad, F., Dickstein, K., Lang, C., Cleland, J. G., ter Maaten, J. M., Metra, M., Anker, S. D., van der Harst, P., Ng, L. L., Meer, P. V. D., van Veldhuisen, D. J., Meyer, S. & 1 others, Voors, A. A., 5 Oct 2019, In : Lancet. 394, 10205, p. 1254-1263 10 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
44 Downloads (Pure)
2017

Development and validation of multivariable models to predict mortality and hospitalization in patients with heart failure

Voors, A. A., Ouwerkerk, W., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Ng, L., Metra, M., ter Maaten, J. M., Lang, C., Hillege, H. L., van der Harst, P., Filippatos, G. S., Dickstein, K., Cleland, J. G. F., Anker, S. D. & Zwinderman, K., 9 May 2017, In : European Journal of Heart Failure. 19, 5, p. 627-634 8 p.

Research output: Contribution to journalArticle

Open Access
File
65 Citations (Scopus)
135 Downloads (Pure)
2011

The impact of renin-angiotensin-aldosterone system blockade on heart failure outcomes and mortality in patients identified to have aortic regurgitation: a large population cohort study

Elder, D. H. J., Wei, L., Szwejkowski, B. R., Libianto, R., Nadir, A., Pauriah, M., Rekhraj, S., Lim, T. K., George, J., Doney, A., Pringle, S. D., Choy, A-M., Struthers, A. D. & Lang, C. C., Nov 2011, In : Journal of the American College of Cardiology. 58, 20, p. 2084-2091 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2019

Bio-adrenomedullin as a marker of congestion in patients with new-onset and worsening heart failure

ter Maaten, J. M., Kremer, D., Demissei, B., Struck, J., Bergmann, A., Anker, S. D., Ng, L. L., Dickstein, K., Metra, M., Samani, N. J., Romaine, S. P. R., Cleland, J. G. F., Girerd, N., Lang, C., van Veldhuisen, D. J. & Voors, A. A., 20 Jun 2019, In : European Journal of Heart Failure. 21, 6, p. 732-743 12 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
174 Downloads (Pure)
2015

Underutilisation of IV nitrates in the treatment of acute heart failure

Mohan, M., Hawkey, S., Baig, F., Choy, A. M. & Lang, C. C., Aug 2015, In : Cardiovascular Therapeutics. 33, 4, p. 247-252 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
11 Citations (Scopus)
2020

Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets

Cao, T. H., Jones, D. J. L., Voors, A. A., Quinn, P. A., Sandhu, J. K., Chan, D. C. S., Parry, H., Mohan, P., Mordi, I., Sama, I. E., Anker, S. D., Cleland, J. G. F., Dickstein, K., Filippatos, G. S., Hillege, H. L., Metra, M., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F. & 2 others, Lang, C. & Ng, L. L., Jan 2020, In : European Journal of Heart Failure. 22, 1, p. 70-80 11 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
69 Downloads (Pure)
2019

Symptom Onset in Aortic Stenosis - Relation to Sex Differences in Left Ventricular Remodelling

Singh, A., Chan, D. C. S., Greenwood, J. P., Dawson, D. K., Sonecki, P., Hogrefe, K., Kelly, D. J., Dhakshinamurthy, V., Lang, C., Khoo, J. P., Sprigings, D., Steeds, R. P., Zhang, R., Ford, I., Jerosch-Herold, M., Yang, J., Li, Z., Ng, L. L. & McCann, G. P., Jan 2019, In : JACC. Cardiovascular Imaging. 12, 1, p. 96-105 10 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
169 Downloads (Pure)
2016

Mean HbA1c and mortality in diabetic individuals with heart failure: a population cohort study

Elder, D. H. J., Singh, J. S. S., Levin, D., Donnelly, L. A., Choy, A-M. J., George, J., Struthers, A. D., Doney, A. S. F. & Lang, C. C., Jan 2016, In : European Journal of Heart Failure. 18, 1, p. 94-102 9 p.

Research output: Contribution to journalArticle

Open Access
File
40 Citations (Scopus)
155 Downloads (Pure)
Open Access
File
32 Citations (Scopus)
265 Downloads (Pure)
2011

The impact of angiotensin converting enzyme inhibitors in aortic valve disease

Elder, D. H., Wei, L., Libianto, R., Nadir, A., Benjamin, S., Lim, T., Pringle, S., Choy, A., Struthers, A. & Lang, C. C., Feb 2011, In : Clinical Pharmacology & Therapeutics. 89, Supplement 1, p. S50-S50 1 p., PII-40.

Research output: Contribution to journalBook/Film/Article review

2020
Open Access
File
4 Downloads (Pure)
2016

Rehabilitation Enablement in Chronic Heart Failure—a facilitated self-care rehabilitation intervention in patients with heart failure with preserved ejection fraction (REACH-HFpEF) and their caregivers: rationale and protocol for a single-centre pilot randomised controlled trial

Eyre, V., Lang, C. C., Smith, K., Jolly, K., Davis, R., Hayward, C., Wingham, J., Abraham, C., Green, C., Warren, F. C., Britten, N., Greaves, C. J., Doherty, P., Austin, J., Van Lingen, R., Singh, S., Buckingham, S., Paul, K., Taylor, R. S., Dalal, H. M. & 1 others, on behalf of the REACH-HF investigators, 25 Oct 2016, In : BMJ Open. 6, 10, p. 1-11 11 p., e012853.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
177 Downloads (Pure)

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

Cameron, A. R., Morrison, V., Levin, D., Mohan, M., Forteath, C., Beall, C., McNeilly, A. D., Balfour, D. J. K., Savinko, T., Wong, A. K. F., Viollet, B., Sakamoto, K., Fagerholm, S. C., Foretz, M., Lang, C. C. & Rena, G., 19 Aug 2016, In : Circulation Research. 119, 5, p. 652-665 14 p.

Research output: Contribution to journalArticle

Open Access
File
143 Citations (Scopus)
258 Downloads (Pure)
2020
Open Access
File
17 Downloads (Pure)
2019

Geographical location affects the levels and association of trimethylamine N-oxide with heart failure mortality in BIOSTAT-CHF: a post-hoc analysis

Yazaki, Y., Salzano, A., Nelson, C. P., Voors, A. A., Anker, S. D., Cleland, J. G., Lang, C. C., Metra, M., Samani, N. J., Ng, L. L. & Suzuki, T., Oct 2019, In : European Journal of Heart Failure. 21, 10, p. 1291-1294 4 p.

Research output: Contribution to journalLetter

Open Access
File
7 Citations (Scopus)
3 Downloads (Pure)