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Author

  • Stewart Fleming
2013

Complementation of juxtaglomerular cell granulation in Ren-1d null mice by human renin

Buckley, C., Nelson, R., Sharp, M., Flemming, S., Kenyon, C., Mullins, L., Steppan, D. & Mullins, J., Apr 2013, In : FASEB Journal. 27, Suppl., 1 p., 1165.20.

Research output: Contribution to journalMeeting abstract

2011

A Comparison of WT1, PTEN and the AKT Pathway in Ovarian Serous Carcinoma vs. Colorectal Adenocarcinoma

Gallacher, M. A. & Fleming, S., Jul 2011, In : Journal of Pathology. 224, S2, p. S24-S24 1 p.

Research output: Contribution to journalSpecial issue

2013

The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia

Srigley, J. R., Delahunt, B., Eble, J. N., Egevad, L., Epstein, J. I., Grignon, D., Hes, O., Moch, H., Montironi, R., Tickoo, S. K., Zhou, M., Argani, P. & ISUP Renal Tumor Panel, Oct 2013, In : American Journal of Surgical Pathology. 37, 10, p. 1469-89 21 p.

Research output: Contribution to journalArticle

612 Citations (Scopus)

Handling and staging of renal cell carcinoma: the International Society of Urological Pathology Consensus (ISUP) conference recommendations

Trpkov, K., Grignon, D. J., Bonsib, S. M., Amin, M. B., Billis, A., Lopez-Beltran, A., Samaratunga, H., Tamboli, P., Delahunt, B., Egevad, L., Montironi, R., Srigley, J. R. & ISUP Renal Tumor Panel, Oct 2013, In : American Journal of Surgical Pathology. 37, 10, p. 1505–1517 13 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)
2014

Evidence for aldosterone-dependent growth of renal cell carcinoma

King, S., Bray, S., Galbraith, S., Christie, L. & Fleming, S., Aug 2014, In : International Journal of Experimental Pathology. 95, 4, p. 244-250 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2013

Renal tumors: diagnostic and prognostic biomarkers

Tan, P. H., Cheng, L., Rioux-Leclercq, N., Merino, M. J., Netto, G., Reuter, V. E., Shen, S. S., Grignon, D. J., Montironi, R., Egevad, L., Srigley, J. R., Delahunt, B., Moch, H. & ISUP Renal Tumor Panel, Oct 2013, In : American Journal of Surgical Pathology. 37, 10, p. 1518–1531 14 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)
2017

Multiple socioeconomic deprivation and impact on survival in patients with primary glomerulonephritis

McQuarrie, E. P., Mackinnon, B., Bell, S., Fleming, S., McNeice, V., Stewart, G., Fox, J. G., Geddes, C. C. & Scottish Renal Biopsy Registry, Feb 2017, In : Clinical Kidney Journal. 10, 1, p. 49-54 6 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
131 Downloads (Pure)

Meta-analysis of the prevalence of renal cancer detected by abdominal ultrasonography

Rossi, S. H., Hsu, R., Blick, C., Goh, V., Nathan, P., Nicol, D., Fleming, S., Sweeting, M., Wilson, E. C. F. & Stewart, G. D., May 2017, In : British Journal of Surgery. 104, 6, p. 648-659 12 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)
2015

Idiopathic hypocomplementemic interstitial nephritis

Kidder, D., Stewart, G. A., Furrie, E. & Fleming, S., Feb 2015, In : Kidney International. 87, 2, p. 485-486 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2011

Asparagine endopeptidase is required for normal kidney physiology and homeostasis

Miller, G., Matthews, S. P., Reinheckel, T., Fleming, S. & Watts, C., May 2011, In : FASEB Journal. 25, 5, p. 1606-1617 12 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2018

Challenges in Pathologic Staging of Renal Cell Carcinoma: A Study of Interobserver Variability Among Urologic Pathologists

Williamson, S. R., Rao, P., Hes, O., Epstein, J. I., Smith, S. C., Picken, M. M., Zhou, M., Tretiakova, M. S., Tickoo, S. K., Chen, Y-B., Reuter, V. E., Fleming, S., Maclean, F. M., Gupta, N. S., Kuroda, N., Delahunt, B., Mehra, R., Przybycin, C. G., Cheng, L., Eble, J. N. & 11 others, Grignon, D. J., Moch, H., Lopez, J. I., Kunju, L. P., Tamboli, P., Srigley, J. R., Amin, M. B., Martignoni, G., Hirsch, M. S., Bonsib, S. M. & Trpkov, K., Sep 2018, In : American Journal of Surgical Pathology. 42, 9, p. 1253-1261 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

Translocation renal cell carcinomas: an evolving entity and a member of the microphthalmia transcription factor-associated family of tumors

Bambury, R. M., Battley, J. E., McCarthy, A., Brady, C., O'Reilly, S., Kelly, P. J., O'Brien, F., Sweeney, P., Fleming, S., Mayer, N. J. & Power, D. G., Sep 2013, In : Clinical Genitourinary Cancer. 11, 3, p. 357-361 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2015

Distal nephron neoplasms

Fleming, S., Mar 2015, In : Seminars in Diagnostic Pathology. 32, 2, p. 114-123 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2019

Dataset for the reporting of carcinoma of renal tubular origin: recommendations from the International Collaboration on Cancer Reporting (ICCR)

Delahunt, B., Srigley, J. R., Judge, M. J., Amin, M. B., Billis, A., Camparo, P., Evans, A. J., Fleming, S., Griffiths, D. F., Lopez-Beltran, A., Martignoni, G., Moch, H., Nacey, J. N. & Zhou, M., Feb 2019, In : Histopathology. 74, 3, p. 377-390 14 p.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
185 Downloads (Pure)
2016

Microsatellite alteration and immunohistochemical expression profile of chromosome 9p21 in patients with sporadic renal cell carcinoma following surgical resection.

El-Mokadem, I., Alison, L., Kidd, T., Garret, K., Pratt, N., Batty, G. D., Fleming, S. & Nabi, G., 31 Jul 2016, In : BMC Cancer. 16, p. 1-10 10 p., 546.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
180 Downloads (Pure)
2018

Phenotypic dissection of the mouse Ren-1(d) knockout by complementation with human renin

Buckley, C., Nelson, R. J., Mullins, L. J., Sharp, M. G. F., Fleming, S., Kenyon, C. J., Semprini, S., Steppan, D., Peti-Peterdi, J., Kurtz, A., Christian, H. & Mullins, J. J., 26 Jan 2018, In : Journal of Biological Chemistry. 293, 4, p. 1151-1162 12 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
178 Downloads (Pure)
2014

Succinate dehydrogenase (SDH)-deficient renal carcinoma: a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients

Gill, A. J., Hes, O., Papathomas, T., Sedivcová, M., Tan, P. H., Agaimy, A., Andresen, P. A., Kedziora, A., Clarkson, A., Toon, C. W., Sioson, L., Watson, N., Chou, A., Paik, J., Clifton-Bligh, R. J., Robinson, B. G., Benn, D. E., Hills, K., Maclean, F., Niemeijer, N. D. & 18 others, Vlatkovic, L., Hartmann, A., Corssmit, E. P. M., van Leenders, G. J. L. H., Przybycin, C., McKenney, J. K., Magi-Galluzzi, C., Yilmaz, A., Yu, D., Nicoll, K. D., Yong, J. L., Sibony, M., Yakirevich, E., Fleming, S., Chow, C. W., Miettinen, M., Michal, M. & Trpkov, K., Dec 2014, In : American Journal of Surgical Pathology. 38, 12, p. 1588-1602 15 p.

Research output: Contribution to journalArticle

Open Access
File
139 Citations (Scopus)
165 Downloads (Pure)

Significance of chromosome 9p status in renal cell carcinoma: a systematic review and quality of the reported studies

El-Mokadem, I., Fitzpatrick, J., Rai, B., Cunningham, J., Pratt, N., Fleming, S. & Nabi, G., 2014, In : BioMed Research International. 2014, 11 p., 521380.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
123 Downloads (Pure)

Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery

El-Mokadem, I., Fitzpatrick, J., Bondad, J., Rauchhaus, P., Cunningham, J., Pratt, N., Fleming, S. & Nabi, G., 23 Sep 2014, In : British Journal of Cancer. 111, 7, p. 1381-1390 10 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
149 Downloads (Pure)
2017

Diagnostic criteria for oncocytic renal neoplasms: a survey of urologic pathologists

Williamson, S. R., Gadde, R., Trpkov, K., Hirsch, M. S., Srigley, J. R., Reuter, V. E., Cheng, L., Priya Kunju, L., Barod, R., Rogers, C. G., Delahunt, B., Hes, O., Eble, J. N., Zhou, M., McKenney, J. K., Martignoni, G., Fleming, S., Grignon, D. J., Moch, H. & Gupta, N. S., May 2017, In : Human Pathology. 63, p. 149-156 8 p.

Research output: Contribution to journalArticle

Open Access
File
34 Citations (Scopus)
202 Downloads (Pure)
Open Access
File
2 Citations (Scopus)
131 Downloads (Pure)
2011

How moderate changes in Akt T-loop phosphorylation impact on tumorigenesis and insulin resistance

Wullschleger, S., Sakamoto, K., Johnstone, L., Duce, S., Fleming, S. & Alessi, D. R., Jan 2011, In : Disease Models & Mechanisms. 4, 1, p. 95-103 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

11 beta Hydroxysteroid Dehydrogenase Type 2 is a Key Component of Neoangiogenesis in Renal Carcinoma and Glioma

Galbraith, S., Gallacher, M., Smith, C., Christie, L. & Fleming, S., Jul 2011, In : Journal of Pathology. 224, S2, p. S33-S33 1 p.

Research output: Contribution to journalSpecial issue

33 Citations (Scopus)
2017

Papillary Renal Cell Carcinoma With Osteosarcomatous Heterologous Differentiation: A Case Report With Molecular Genetic Analysis and Review of the Literature

Aird, J. J., Nic An Riogh, A. U., Fleming, S., Hislop, R. G., Sweeney, P. & Mayer, N., 1 Dec 2017, In : International Journal of Surgical Pathology. 28, 8, p. 745-750 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2011

The D153del Mutation in GNB3 Gene Causes Tissue Specific Signalling Patterns and an Abnormal Renal Morphology in Rge Chickens

Tummala, H., Fleming, S., Hocking, P. M., Wehner, D., Naseem, Z., Ali, M., Inglehearn, C. F., Zhelev, N. & Lester, D. H., 22 Aug 2011, In : PLoS ONE. 6, 8, p. - 11 p., e21156.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2013

The International Society of Urological Pathology (ISUP) grading system for renal cell carcinoma and other prognostic parameters

Delahunt, B., Cheville, J. C., Martignoni, G., Humphrey, P. A., Magi-Galluzzi, C., McKenney, J., Egevad, L., Algaba, F., Moch, H., Grignon, D. J., Montrioni, R., Srigley, J. R. & ISUP Renal Tumor Panel, Oct 2013, In : American Journal of Surgical Pathology. 37, 10, p. 1490–1504 15 p.

Research output: Contribution to journalArticle

345 Citations (Scopus)
2015

Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis

Cardaci, S., Zheng, L., Mackay, G., van den Broek, N. J. F., MacKenzie, E. D., Nixon, C., Stevenson, D., Tumanov, S., Bulusu, V., Kamphorst, J. J., Vazquez, A., Fleming, S., Schiavi, F., Kalna, G., Blyth, K., Strathdee, D. & Gottlieb, E., 24 Aug 2015, In : Nature Cell Biology. 17, 10, p. 1317-1326 13 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)
2019

Periprostatic Fat Adipokines Expression Correlated with Prostate Cancer Aggressiveness in Men Undergoing Radical Prostatectomy for Clinically Localised Disease

Dahran, N., Szewczyk-Bieda, M., Vinnicombe, S., Fleming, S. & Nabi, G., Jun 2019, In : BJU International. 123, 6, p. 985-994 10 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
127 Downloads (Pure)
2016

Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer

Palmer, S., Litvinova, K., Dunaev, A., Fleming, S., McGloin, D. & Nabi, G., 7 Mar 2016, In : Biomedical Optics Express. 7, 4, p. 1193-2000 8 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
188 Downloads (Pure)
2014

Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling

Atrih, A., Mudaliar, M. A. V., Zakikhani, P., Lamont, D. J., Huang, J. T-J., Bray, S. E., Barton, G., Fleming, S. & Nabi, G., 2014, In : British Journal of Cancer. 110, 6, p. 1622-1633 12 p.

Research output: Contribution to journalArticle

Open Access
File
40 Citations (Scopus)
173 Downloads (Pure)
2016

Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer

El-Mokadem, I., Kidd, T., Pratt, N., Fleming, S. & Nabi, G., 22 Sep 2016, In : Oncotarget. 7, 45, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
151 Downloads (Pure)
2015

Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

Kovac, M., Navas, C., Horswell, S., Salm, M., Bardella, C., Rowan, A., Stares, M., Castro-Giner, F., Fisher, R., de Bruin, E. C., Kovacova, M., Gorman, M., Makino, S., Williams, J., Jaeger, E., Jones, A., Howarth, K., Larkin, J., Pickering, L., Gore, M. & 25 others, Nicol, D. L., Hazell, S., Stamp, G., O'Brien, T., Challacombe, B., Matthews, N., Phillimore, B., Begum, S., Rabinowitz, A., Varela, I., Chandra, A., Horsfield, C., Polson, A., Tran, M., Bhatt, R., Terracciano, L., Eppenberger-Castori, S., Protheroe, A., Maher, E., El Bahrawy, M., Fleming, S., Ratcliffe, P., Heinimann, K., Swanton, C. & Tomlinson, I., 19 Mar 2015, In : Nature Communications. 6, 11 p., 6336.

Research output: Contribution to journalArticle

68 Citations (Scopus)
2014

Signalling pathways in succinate dehydrogenase B-associated renal carcinoma

Fleming, S., Mayer, N. J., Vlatkovic, L. J., McLean, J., McConachie, M. & Baty, D., Mar 2014, In : Histopathology. 64, 4, p. 477-483 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2013

Generation and characterisation of keratin 7 (K7) knockout mice

Sandilands, A., Smith, F. J. D., Lunny, D. P., Campbell, L. E., Davidson, K. M., MacCallum, S. F., Corden, L. D., Christie, L., Fleming, S., Lane, E. B. & McLean, W. H. I., 31 May 2013, In : PLoS ONE. 8, 5, 11 p., e64404.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2015

Acute tubulointerstitial nephritis in Scotland

Valluri, A., Hetherington, L., McQuarrie, E., Fleming, S., Kipgen, D., Geddes, C. C., Mackinnon, B. & Bell, S., 2015, In : QJM : an International Journal of Medicine. 108, 7, p. 527-532 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2013

The use of steroids in acute tubulo-interstitial nephritis. A multicentre retrospective study

Hetherington, L., Valluri, A., McQuarrie, E., Fleming, S., Geddes, C., Bell, S. & MacKinnon, B., May 2013, In : Nephrology Dialysis Transplantation. 28, supp. 1, p. i343-i343 1 p., MP145.

Research output: Contribution to journalMeeting abstract

2011

Renal Tumors Associated With Germline SDHB Mutation Show Distinctive Morphology

Gill, A. J., Pachter, N. S., Chou, A., Young, B., Clarkson, A., Tucker, K. M., Winship, I. M., Earls, P., Benn, D. E., Robinson, B. G., Fleming, S. & Clifton-Bligh, R. J., Oct 2011, In : American Journal of Surgical Pathology. 35, 10, p. 1578-1585 8 p.

Research output: Contribution to journalArticle

132 Citations (Scopus)

Effect of PI3K-and mTOR-specific inhibitors on spontaneous B-cell follicular lymphomas in PTEN/LKBI-deficient mice

Garcia-Martinez, J. M., Wullschleger, S., Preston, G., Guichard, S., Fleming, S., Alessi, D. R. & Duce, S. L., 29 Mar 2011, In : British Journal of Cancer. 104, 7, p. 1116-1125 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2016

Renal squamous cell carcinoma of a native kidney after renal transplant: a case report

Jakes, A., Jani, P., Menon, M., Adams, K., Edey, M., Fleming, S. & Bhandari, S., 2016, In : Transplantation Proceedings. 48, 1, p. 259-261 3 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
191 Downloads (Pure)
2015

Kidney biopsy findings in primary Sjogren syndrome

Kidder, D., Rutherford, E., Kipgen, D., Fleming, S., Geddes, C. & Stewart, G. A., 2015, In : Nephrology Dialysis Transplantation. 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2014

Risk of AKI with gentamicin as surgical prophylaxis

Bell, S., Davey, P., Nathwani, D., Marwick, C., Vadiveloo, T., Sneddon, J., Patton, A., Bennie, M., Fleming, S. & Donnan, P. T., Nov 2014, In : Journal of the American Society of Nephrology. 25, 11, p. 2625-2632 8 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)