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Author

  • Iva Hopkins Navratilova
2012

Biosensor-Based Approach to the Identification of Protein Kinase Ligands with Dual-Site Modes of Action

Navratilova, I., Macdonald, G., Robinson, C., Hughes, S., Mathias, J., Phillips, C. & Cook, A., Feb 2012, In : Journal of Biomolecular Screening. 17, 2, p. 183-193 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2013

A novel allosteric inhibitor of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei

Urbaniak, M. D., Collie, I. T., Fang, W., Aristotelous, T., Eskilsson, S., Raimi, O. G., Harrison, J., Navratilova, I. H., Frearson, J. A., van Aalten, D. M. F. & Ferguson, M. A. J., 20 Sep 2013, In : ACS Chemical Biology. 8, 9, p. 1981-1987 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2016

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening

Navratilova, I., Aristotelous, T., Picaud, S., Chaikuad, A., Knapp, S., Filappakopoulos, P. & Hopkins, A. L., 8 Dec 2016, In : ACS Medicinal Chemistry Letters. 7, 12, p. 1213-1218 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2012

O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis

Schimpl, M., Zheng, X., Borodkin, V. S., Blair, D. E., Ferenbach, A. T., Schüttelkopf, A. W., Navratilova, I., Aristotelous, T., Albarbarawi, O., Robinson, D. A., van Aalten, D. M. F. & Macnaughtan, M. A., 2012, In : Nature Chemical Biology.

Research output: Contribution to journalArticle

79 Citations (Scopus)
2020

Mining Public Domain Data to Develop Selective DYRK1A Inhibitors

Henderson, S. H., Sorrell, F., Bennett, J., Hanley, M. T., Robinson, S., Hopkins Navratilova, I., Elkins, J. M. & Ward, S. E., 13 Aug 2020, In : ACS Medicinal Chemistry Letters. 11, 8, p. 1620-1626 7 p.

Research output: Contribution to journalArticle

Open Access
File
7 Downloads (Pure)
2013

Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain

Rao, F. V., Schüttelkopf, A. W., Dorfmueller, H. C., Ferenbach, A. T., Navratilova, I. & van Aalten, D. M. F., 2 Oct 2013, In : Open Biology. 3, 130021.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2014

Fragment screening by SPR and advanced application to GPCRs

Shepherd, C. A., Hopkins, A. L. & Navratilova, I., Nov 2014, In : Progress in Biophysics and Molecular Biology. 116, 2-3, p. 113-123 11 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
2013

Discovery of Β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor

Aristotelous, T., Ahn, S., Shukla, A. K., Gawron, S., Sassano, M. F., Kahsai, A. W., Wingler, L. M., Zhu, X., Tripathi-Shukla, P., Huang, X-P., Riley, J., Besnard, J., Read, K. D., Roth, B. L., Gilbert, I. H., Hopkins, A. L., Lefkowitz, R. J. & Navratilova, I., 2013, In : ACS Medicinal Chemistry Letters. 4, 10, p. 1005-1010 6 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2019

Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates

Cahill, S. T., Tyrrell, J. M., Navratilova, I. H., Calvopiña, K., Robinson, S. W., Lohans, C. T., McDonough, M. A., Cain, R., Fishwick, C. W. G., Avison, M. B., Walsh, T. R., Schofield, C. J. & Brem, J., 1 Apr 2019, In : Biochimica et Biophysica Acta: General Subjects. 1863, 4, p. 742-748 7 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
60 Downloads (Pure)