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Author

  • Iva Hopkins Navratilova
2017

A mutant O-GlcNAcase enriches Drosophila developmental regulators

Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In : Nature Chemical Biology. 13, 8, p. 882-887 8 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
182 Downloads (Pure)
2012

Biosensor-Based Approach to the Identification of Protein Kinase Ligands with Dual-Site Modes of Action

Navratilova, I., Macdonald, G., Robinson, C., Hughes, S., Mathias, J., Phillips, C. & Cook, A., Feb 2012, In : Journal of Biomolecular Screening. 17, 2, p. 183-193 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2020

Mining Public Domain Data to Develop Selective DYRK1A Inhibitors

Henderson, S. H., Sorrell, F., Bennett, J., Hanley, M. T., Robinson, S., Hopkins Navratilova, I., Elkins, J. M. & Ward, S. E., 13 Aug 2020, In : ACS Medicinal Chemistry Letters. 11, 8, p. 1620-1626 7 p.

Research output: Contribution to journalArticle

Open Access
File
6 Downloads (Pure)
2012

O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis

Schimpl, M., Zheng, X., Borodkin, V. S., Blair, D. E., Ferenbach, A. T., Schüttelkopf, A. W., Navratilova, I., Aristotelous, T., Albarbarawi, O., Robinson, D. A., van Aalten, D. M. F. & Macnaughtan, M. A., 2012, In : Nature Chemical Biology.

Research output: Contribution to journalArticle

78 Citations (Scopus)
2014

Fragment screening by SPR and advanced application to GPCRs

Shepherd, C. A., Hopkins, A. L. & Navratilova, I., Nov 2014, In : Progress in Biophysics and Molecular Biology. 116, 2-3, p. 113-123 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2016

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening

Navratilova, I., Aristotelous, T., Picaud, S., Chaikuad, A., Knapp, S., Filappakopoulos, P. & Hopkins, A. L., 8 Dec 2016, In : ACS Medicinal Chemistry Letters. 7, 12, p. 1213-1218 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2018

Surveying GPCR solubilisation conditions using surface plasmon resonance

Navratilova, I. H., Aristotelous, T., Bird, L. E. & Hopkins, A. L., 1 Sep 2018, In : Analytical Biochemistry. 556, p. 23-34 12 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
23 Downloads (Pure)

O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry

Borodkin, V. S., Rafie, K., Selvan, N., Aristotelous, T., Navratilova, I., Ferenbach, A. T. & Van Aalten, D. M. F., 18 May 2018, In : ACS Chemical Biology. 13, 5, p. 1353-1360 8 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
148 Downloads (Pure)

Inhibitors against Fungal Cell Wall Remodeling Enzymes

Delso, I., Valero-Gonzalez, J., Gomollón-Bel, F., Castro-López, J., Fang, W., Navratilova, I., van Aalten, D. M. F., Tejero, T., Merino, P. & Hurtado-Guerrero, R., 22 Jan 2018, In : ChemMedChem. 13, 2, p. 128-132 5 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
159 Downloads (Pure)
2019

Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates

Cahill, S. T., Tyrrell, J. M., Navratilova, I. H., Calvopiña, K., Robinson, S. W., Lohans, C. T., McDonough, M. A., Cain, R., Fishwick, C. W. G., Avison, M. B., Walsh, T. R., Schofield, C. J. & Brem, J., 1 Apr 2019, In : Biochimica et Biophysica Acta: General Subjects. 1863, 4, p. 742-748 7 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
58 Downloads (Pure)
2018

Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus

Mousnier, A., Bell, A. S., Swieboda, D. P., Morales-Sanfrutos, J., Pérez-Dorado, I., Brannigan, J. A., Newman, J., Ritzefeld, M., Hutton, J. A., Guedán, A., Asfor, A. S., Robinson, S. W., Hopkins-Navratilova, I., Wilkinson, A. J., Johnston, S. L., Leatherbarrow, R. J., Tuthill, T. J., Solari, R. & Tate, E. W., Jun 2018, In : Nature Chemistry. 10, 6, p. 599-606 8 p.

Research output: Contribution to journalArticle

Open Access
File
26 Citations (Scopus)
137 Downloads (Pure)