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2020
TDP-43, a protein central to amyotrophic lateral sclerosis, is destabilized by tankyrase-1 and -2
McGurk, L., Rifai, O. & Bonini, N. M., 23 Jun 2020, In: Journal of Cell Science. 133, 12Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)19 Downloads (Pure) -
First person - Leeanne McGurk
McGurk, L., Jun 2020, In: Journal of Cell Science. 133, 12, 2 p., jcs.248773.Research output: Contribution to journal › Comment/debate › peer-review
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Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila
Deng, P., Khan, A., Jacobson, D., Sambrani, N., McGurk, L., Li, X., Jayasree, A., Hejatko, J., Shohat-Ophir, G., O'Connell, M. A., Li, J. B. & Keegan, L. P., 27 Mar 2020, In: Nature Communications. 11, 1, p. 1580 1580.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)52 Downloads (Pure) -
2014
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
Kim, H. J., Raphael, A. R., Ladow, E. S., Mcgurk, L., Weber, R. A., Trojanowski, J. Q., Lee, V. M. Y., Finkbeiner, S., Gitler, A. D. & Bonini, N. M., Feb 2014, In: Nature Genetics. 46, 2, p. 152-160 9 p.Research output: Contribution to journal › Article › peer-review
207 Citations (Scopus) -
2015
Drosophila as an in vivo model for human neurodegenerative disease
McGurk, L., Berson, A. & Bonini, N. M., Oct 2015, In: Genetics. 201, 2, p. 377-402 26 p.Research output: Contribution to journal › Article › peer-review
123 Citations (Scopus) -
2020
Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy
Khan, A., Paro, S., McGurk, L., Sambrani, N., Hogg, M. C., Brindle, J., Pennetta, G., Keegan, L. P. & O'Connell, M. A., 14 Feb 2020, In: BMC Biology. 18, 1, 16 p., 15.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)55 Downloads (Pure) -
2014
Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72
McGurk, L., Lee, V. M., Trojanowksi, J. Q., Van Deerlin, V. M., Lee, E. B. & Bonini, N. M., 1 Sep 2014, In: Journal of Neuropathology and Experimental Neurology. 73, 9, p. 837-845 9 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus)