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  • Colin Palmer
2017

Genome-Wide Association Study of Asthma Exacerbations in European Children Treated with Inhaled Corticosteroids

Vijverberg, S. J. H., Hernandez-Pacheco, N., Farzan, N., Francis, B., Flores, C., Schieck, M., Soares, P., Karimi, L., Tavendale, R., Berce, V., Repnik, K., Verhamme, K. M. C., Potocnik, U., Mukhopadhyay, S., Pirmohamed, M., Palmer, C. N., Turner, S. W., Hawcutt, D. B., Kabesch, M., Pino-Yanes, M. & 1 others, Maitland-van der Zee, A-H., Aug 2017, In : Pharmacoepidemiology and Drug Safety. 26, p. 25-26

Research output: Contribution to journalMeeting abstract

2018

MSR1 repeats modulate gene expression and affect risk of breast and prostate cancer

Rose, A. M., Krishan, A., Chakarova, C. F., Moya, L., Chambers, S., Hollands, M., Illingworth, J. C., Williams, S. M. G., James, H. E., Shah, A. Z., Palmer, C. N. A., Chakravarti, A., Berg, J. N., Batra, J. & Bhattacharya, S. S., May 2018, In : Annals of Oncology. 29, 5, p. 1292-1303 12 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
105 Downloads (Pure)

Variants in genes coding for glutathione S-transferases and asthma outcomes in children

Pharmacogenomics in Childhood Asthma Consortium, Turner, S., Francis, B., Wani, N., Vijverberg, S., Pino-Yanes, M., Mukhopadhyay, S., Tavendale, R., Palmer, C., Burchard, E. G., Merid, S. K., Melén, E. & Maitland-van der Zee, A. H., Jun 2018, In : Pharmacogenomics. 19, 8, p. 707-713 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017
Open Access
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1 Citation (Scopus)
152 Downloads (Pure)

Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium

Farzan, N., Vijverberg, S. J. H., Andiappan, A. K., Arianto, L., Berce, V., Blanca-López, N., Bisgaard, H., Bønnelykke, K., Burchard, E. G., Campo, P., Canino, G., Carleton, B., Celedón, J. C., Chew, F. T., Chiang, W. C., Cloutier, M. M., Daley, D., Den Dekker, H. T., Dijk, N. F., Duijts, L. & 26 others, Flores, C., Forno, E., Hawcutt, D. B., Hernandez-Pacheco, N., de Jongste, J. C., Kabesch, M., Koppelman, G. H., Manolopoulos, V. G., Melén, E., Mukhopadhyay, S., Nilsson, S., Palmer, C. N., Pino-Yanes, M., Pirmohamed, M., Potočnki, U., Raaijmakers, J. A. M., Repnik, K., Schieck, M., Sio, Y. Y., Smyth, R. L., Szalai, C., Tantisira, K. G., Turner, S., van der Schee, M. P., Verhamme, K. M. & Maitland-van der Zee, A. H., 1 Jul 2017, In : Pharmacogenomics. 18, 10

Research output: Contribution to journalArticle

15 Citations (Scopus)

CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia

Siddiqui, M. K., Veluchamy, A., Maroteau, C., Tavendale, R., Carr, F., Pearson, E., Colhoun, H., Morris, A. D., George, J., Doney, A., Pirmohamed, M., Alfirevic, A., Wadelius, M., Maitland-van der Zee, A. H., Ridker, P. M., Chasman, D. I., Palmer, C. N. A. & PREDICTION-ADR Consortium, Aug 2017, In : Circulation: Cardiovascular Genetics. 10, 4, e001737 .

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Opt-in method is vital for data sharing

Sullivan, F., McKinstry, B. & Palmer, C., 5 Aug 2016, In : BMJ. 354, 1 p., i4293.

Research output: Contribution to journalLetter

Effect of Serotonin Transporter 5HTTLPR Polymorphism on Gastrointestinal Intolerance to Metformin: A GoDARTS Study

Dujic, T., Zhou, K., Tavendale, R., Palmer, C. & Pearson, E., 1 Nov 2016, In : Diabetes Care. 39, 11, p. 1896-1901 6 p.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
162 Downloads (Pure)
2019

A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity

Meng, W., Chan, B., Ezeonwumelu, C., Hebert, H., Campbell, A., Soler, V. & Palmer, C., 2 Jul 2019, In : Ophthalmic Genetics. 40, 3, p. 252-258 7 p.

Research output: Contribution to journalArticle

Open Access
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6 Downloads (Pure)

Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease

Veluchamy, A., Ballerini, L., Vitart, V., Schraut, K. E., Kirin, M., Campbell, H., Joshi, P. K., Relan, D., Harris, S., Vaidya, S. S. ., Dhillon, B., Zhou, K., Pearson, E., Hayward, C., Polašek, O., Deary, I. J., MacGillivray, T. J., Wilson, J. F., Trucco, M., Palmer, C. & 1 others, Doney, A., Dec 2019, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 39, 12, p. 2542-2552 11 p.

Research output: Contribution to journalArticle

Open Access
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103 Downloads (Pure)
2016

Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children

Rautanen, A., Pirinen, M., Mills, T. C., Rockett, K. A., Strange, A., Ndungu, A. W., Naranbhai, V., Gilchrist, J. J., Bellenguez, C., Freeman, C., Band, G., Bumpstead, S. J., Edkins, S., Giannoulatou, E., Gray, E., Dronov, S., Hunt, S. E., Langford, C., Pearson, R. D., Su, Z. & 31 others, Vukcevic, D., Macharia, A. W., Uyoga, S., Ndila, C., Mturi, N., Njuguna, P., Mohammed, S., Berkley, J. A., Mwangi, I., Mwarumba, S., Kitsao, B. S., Lowe, B. S., Morpeth, S. C., Khandwalla, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Deloukas, P. & Kenyan Bacteraemia Study Group, 2 Jun 2016, In : American Journal of Human Genetics. 98, 6, p. 1092-1100 9 p.

Research output: Contribution to journalArticle

Open Access
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19 Citations (Scopus)
213 Downloads (Pure)
2019

Application of pharmacogenomics and bioinformatics to exemplify the utility of human ex vivo organoculture models in the field of precision medicine

Cowan, K., MacLuskie, G., Finch, M., Palmer, C. N. A., Hair, J., Bylesjo, M., Lynagh, S., Brankin, P., McNeil, M., Low, C., Mallinson, D., Gourlay, E. M., Child, H., Cheyne, L. & Bunton, D. C., 20 Dec 2019, In : PLoS ONE. 14, 12, p. 1-15 15 p., e0226564.

Research output: Contribution to journalArticle

Open Access
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57 Downloads (Pure)

Associations of autozygosity with a broad range of human phenotypes

Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., Bartz, T. M. & 416 others, Baumbach, C., Biino, G., Bixley, M. J., Brumat, M., Chai, J-F., Corre, T., Cousminer, D. L., Dekker, A. M., Eccles, D. A., van Eijk, K. R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S. D., de Haan, H. G., Harris, S. E., Hofer, E., Huerta-Chagoya, A., Igartua, C., Jansen, I. E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M. E., Li, S. A., Li-Gao, R., Mahajan, A., Matsuda, K., Meidtner, K., Meng, W., Montasser, M. E., van der Most, P. J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R. B., Priyanka, T. D. S., Rizzi, F., Salvi, E., Sapkota, B. R., Shriner, D., Skotte, L., Smart, M. C., Smith, A. V., van der Spek, A., Spracklen, C. N., Strawbridge, R. J., Tajuddin, S. M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H. R., Wootton, R. E., Yanek, L. R., Yao, J., Yousri, N. A., Zhao, W., Adeyemo, A. A., Afaq, S., Aguilar-Salinas, C. A., Akiyama, M., Albert, M. L., Allison, M. A., Alver, M., Aung, T., Azizi, F., Bentley, A. R., Boeing, H., Boerwinkle, E., Borja, J. B., de Borst, G. J., Bottinger, E. P., Broer, L., Campbell, H., Chanock, S., Chee, M-L., Chen, G., Chen, Y-D. I., Chen, Z., Chiu, Y-F., Cocca, M., Collins, F. S., Concas, M. P., Corley, J., Cugliari, G., van Dam, R. M., Damulina, A., Daneshpour, M. S., Day, F. R., Delgado, G. E., Dhana, K., Doney, A. S. F., Dörr, M., Doumatey, A. P., Dzimiri, N., Ebenesersdóttir, S. S., Elliott, J., Elliott, P., Ewert, R., Felix, J. F., Fischer, K., Freedman, B. I., Girotto, G., Goel, A., Gögele, M., Goodarzi, M. O., Graff, M., Granot-Hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D. F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S. P., Haiman, C. A., Halevy, A., Harris, T. B., Hedayati, M., van Heel, D. A., Hirata, M., Höfer, I., Hsiung, C. A., Huang, J., Hung, Y-J., Ikram, M. A., Jagadeesan, A., Jousilahti, P., Kamatani, Y., Kanai, M., Kerrison, N. D., Kessler, T., Khaw, K-T., Khor, C. C., de Kleijn, D. P. V., Koh, W-P., Kolcic, I., Kraft, P., Krämer, B. K., Kutalik, Z., Kuusisto, J., Langenberg, C., Launer, L. J., Lawlor, D. A., Lee, I-T., Lee, W-J., Lerch, M. M., Li, L., Liu, J., Loh, M., London, S. J., Loomis, S., Lu, Y., Luan, J., Mägi, R., Manichaikul, A. W., Manunta, P., Másson, G., Matoba, N., Mei, X. W., Meisinger, C., Meitinger, T., Mezzavilla, M., Milani, L., Millwood, I. Y., Momozawa, Y., Moore, A., Morange, P-E., Moreno-Macías, H., Mori, T. A., Morrison, A. C., Muka, T., Murakami, Y., Murray, A. D., de Mutsert, R., Mychaleckyj, J. C., Nalls, M. A., Nauck, M., Neville, M. J., Nolte, I. M., Ong, K. K., Orozco, L., Padmanabhan, S., Pálsson, G., Pankow, J. S., Pattaro, C., Pattie, A., Polasek, O., Poulter, N., Pramstaller, P. P., Quintana-Murci, L., Räikkönen, K., Ralhan, S., Rao, D. C., van Rheenen, W., Rich, S. S., Ridker, P. M., Rietveld, C. A., Robino, A., van Rooij, F. J. A., Ruggiero, D., Saba, Y., Sabanayagam, C., Sabater-Lleal, M., Sala, C. F., Salomaa, V., Sandow, K., Schmidt, H., Scott, L. J., Scott, W. R., Sedaghati-Khayat, B., Sennblad, B., van Setten, J., Sever, P. J., Sheu, W. H-H., Shi, Y., Shrestha, S., Shukla, S. R., Sigurdsson, J. K., Sikka, T. T., Singh, J. R., Smith, B. H., Stančáková, A., Stanton, A., Starr, J. M., Stefansdottir, L., Straker, L., Sulem, P., Sveinbjornsson, G., Swertz, M. A., Taylor, A. M., Taylor, K. D., Terzikhan, N., Tham, Y-C., Thorleifsson, G., Thorsteinsdottir, U., Tillander, A., Tracy, R. P., Tusié-Luna, T., Tzoulaki, I., Vaccargiu, S., Vangipurapu, J., Veldink, J. H., Vitart, V., Völker, U., Vuoksimaa, E., Wakil, S. M., Waldenberger, M., Wander, G. S., Wang, Y. X., Wareham, N. J., Wild, S., Yajnik, C. S., Yuan, J-M., Zeng, L., Zhang, L., Zhou, J., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Becker, D. M., Lehne, B., Bennett, D. A., van den Berg, L. H., Berndt, S. I., Bharadwaj, D., Bielak, L. F., Bochud, M., Boehnke, M., Bouchard, C., Bradfield, J. P., Brody, J. A., Campbell, A., Carmi, S., Caulfield, M. J., Cesarini, D., Chambers, J. C., Chandak, G. R., Cheng, C-Y., Ciullo, M., Cornelis, M., Cusi, D., Smith, G. D., Deary, I. J., Dorajoo, R., van Duijn, C. M., Ellinghaus, D., Erdmann, J., Eriksson, J. G., Evangelou, E., Evans, M. K., Faul, J. D., Feenstra, B., Feitosa, M., Foisy, S., Franke, A., Friedlander, Y., Gasparini, P., Gieger, C., Gonzalez, C., Goyette, P., Grant, S. F. A., Griffiths, L. R., Groop, L., Gudnason, V., Gyllensten, U., Hakonarson, H., Hamsten, A., van der Harst, P., Heng, C-K., Hicks, A. A., Hochner, H., Huikuri, H., Hunt, S. C., Jaddoe, V. W. V., De Jager, P. L., Johannesson, M., Johansson, Å., Jonas, J. B., Jukema, J. W., Junttila, J., Kaprio, J., Kardia, S. L. R., Karpe, F., Kumari, M., Laakso, M., van der Laan, S. W., Lahti, J., Laudes, M., Lea, R. A., Lieb, W., Lumley, T., Martin, N. G., März, W., Matullo, G., McCarthy, M. I., Medland, S. E., Merriman, T. R., Metspalu, A., Meyer, B. F., Mohlke, K. L., Montgomery, G. W., Mook-Kanamori, D., Munroe, P. B., North, K. E., Nyholt, D. R., O'connell, J. R., Ober, C., Oldehinkel, A. J., Palmas, W., Palmer, C., Pasterkamp, G. G., Patin, E., Pennell, C. E., Perusse, L., Peyser, P. A., Pirastu, M., Polderman, T. J. C., Porteous, D. J., Posthuma, D., Psaty, B. M., Rioux, J. D., Rivadeneira, F., Rotimi, C., Rotter, J. I., Rudan, I., Den Ruijter, H. M., Sanghera, D. K., Sattar, N., Schmidt, R., Schulze, M. B., Schunkert, H., Scott, R. A., Shuldiner, A. R., Sim, X., Small, N., Smith, J. A., Sotoodehnia, N., Tai, E-S., Teumer, A., Timpson, N. J., Toniolo, D., Tregouet, D-A., Tuomi, T., Vollenweider, P., Wang, C. A., Weir, D. R., Whitfield, J. B., Wijmenga, C., Wong, T-Y., Wright, J., Yang, J., Yu, L., Zemel, B. S., Zonderman, A. B., Perola, M., Magnusson, P. K. E., Uitterlinden, A. G., Kooner, J. S., Chasman, D. I., Loos, R. J. F., Franceschini, N., Franke, L., Haley, C. S., Hayward, C., Walters, R. G., Perry, J. R. B., Esko, T., Helgason, A., Stefansson, K., Joshi, P. K., Kubo, M. & Wilson, J. F., 31 Oct 2019, In : Nature Communications. 10, 1, p. 1-17 17 p., 4957.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
67 Downloads (Pure)
2018

Lp-PLA2 activity is associated with increased risk of diabetic retinopathy: a longitudinal disease progression study

Siddiqui, M. K., Kennedy, G., Carr, F., Doney, A., Pearson, E., Morris, A., Johnson, T., McLaughlin, M. M., Williams, R. E. & Palmer, C., Jun 2018, In : Diabetologia. 61, 6, p. 1344-1353 10 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
185 Downloads (Pure)
2020

The impact of phenotype, ethnicity and genotype on progression of Type 2 diabetes mellitus

Thakarakkattil Narayanan Nair, A., Donnelly, L. A., Dawed, A. Y., Gan, S., Anjana, R. M., Mohan, V., Palmer, C. & Pearson, E., 20 Apr 2020, In : Endocrinology, Diabetes & Metabolism. 3, 2, p. 1-11 11 p., e00108.

Research output: Contribution to journalReview article

Open Access
File
46 Downloads (Pure)

Genetic correlations between pain phenotypes and depression and neuroticism

Meng, W., Adams, M. J., Reel, P., Rajendrakumar, A., Huang, Y., Deary, I. J., Palmer, C. N. A., McIntosh, A. M. & Smith, B. H., Mar 2020, In : European Journal of Human Genetics. 28, p. 358-366 9 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
75 Downloads (Pure)
Open Access
File
17 Downloads (Pure)
2016

Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease

Stitziel, N. O., Stirrups, K. E., Masca, N. G. D., Erdmann, J., Ferrario, P. G., König, I. R., Weeke, P. E., Webb, T. R., Auer, P. L., Schick, U. M., Lu, Y., Zhang, H., Dube, M. P., Goel, A., Farrall, M., Peloso, G. M., Won, H. H., Do, R., Van Iperen, E., Kanoni, S. & 109 others, Kruppa, J., Mahajan, A., Scott, R. A., Willenborg, C., Braund, P. S., Van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Merlini, P. A., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C. M., El-Mokhtari, N. E., Franke, A., Gottesman, O., Heilmann, S., Hengstenberg, C., Hoffmann, P., Holmen, O. L., Hveem, K., Jansson, J. H., Jöckel, K. H., Kessler, T., Kriebel, J., Laugwitz, K. L., Marouli, E., Martinelli, N., McCarthy, M. I., van Zuydam, N. R., Meisinger, C., Esko, T., Mihailov, E., Escher, S. A., Alver, M., Moebus, S., Morris, A. D., Müller-Nurasyid, M., Nikpay, M., Olivieri, O., Perreault, L. P. L., AlQarawi, A., Robertson, N. R., Akinsanya, K. O., Reilly, D. F., Vogt, T. F., Yin, W., Asselbergs, F. W., Kooperberg, C., Jackson, R. D., Stahl, E., Strauch, K., Varga, T. V., Waldenberger, M., Zeng, L., Kraja, A. T., Liu, C., Ehret, G. B., Newton-Cheh, C., Chasman, D. I., Chowdhury, R., Ferrario, M., Ford, I., Jukema, J. W., Kee, F., Kuulasmaa, K., Nordestgaard, B. G., Perola, M., Saleheen, D., Sattar, N., Surendran, P., Tregouet, D., Young, R., Howson, J. M. M., Butterworth, A. S., Danesh, J., Ardissino, D., Bottinger, E. P., Erbel, R., Franks, P. W., Girelli, D., Hall, A. S., Hovingh, G. K., Kastrati, A., Lieb, W., Meitinger, T., Kraus, W. E., Shah, S. H., McPherson, R., Orho-Melander, M., Melander, O., Metspalu, A., Palmer, C. N. A., Peters, A., Rader, D. J., Reilly, M. P., Loos, R. J. F., Reiner, A. P., Roden, D. M., Tardif, J. C., Thompson, J. R., Wareham, N. J., Watkins, H., Willer, C. J., Kathiresan, S., Deloukas, P., Samani, N. J. & Schunkert, H., 24 Mar 2016, In : New England Journal of Medicine. 374, 12, p. 1134-1144 11 p.

Research output: Contribution to journalArticle

Open Access
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227 Citations (Scopus)
316 Downloads (Pure)
2019

Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank

Meng, W., Adams, M. J., Palmer, C. N. A., 23andMe Research Team, Shi, J., Auton, A., Ryan, K. A., Jordan, J. M., Mitchell, B. D., Jackson, R. D., Yau, M. S., McIntosh, A. M. & Smith, B. H., 28 Aug 2019, In : Communications Biology. 2, p. 1-8 8 p., 321.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
88 Downloads (Pure)

Multiethnic Genome-wide Association Study of Diabetic Retinopathy using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

Pollack, S., Igo, R. P., Jensen, R. A., Christiansen, M., Li, X., Cheng, C-Y., Ng, M. C. Y., Smith, A. V., Rossin, E. J., Segrè, A. V., Davoudi, S., Tan, G. S., Ida Chen, Y-D., Kuo, J. Z., Dimitrov, L. M., Stanwyck, L. K., Meng, W., Hosseini, S. M., Imamura, M., Nousome, D. & 33 others, Kim, J., Hai, Y., Jia, Y., Ahn, J., Leong, A., Shah, K., Park, K. H., Guo, X., Ipp, E., Taylor, K. D., Adler, S. G., Sedor, J. R., Freedman, B. I., Lee, I-T., H-H Sheu, W., Kubo, M., Takahashi, A., Hadjadj, S., Marre, M., Tregouet, D-A., Mckean-Cowdin, R., Varma, R., McCarthy, M. I., Groop, L., Ahlqvist, E., Morris, A., Doney, A., Colhoun, H. M., Mitchell, P., Paterson, A. D., Palmer, C., Price, A. & Sobrin, L., 21 Jan 2019, In : Diabetes. 68, 2, p. 441-456 16 p.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
233 Downloads (Pure)
2018

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., Payne, A. J., Steinthorsdottir, V., Scott, R. A., Grarup, N., Cook, J. P., Schmidt, E. M., Wuttke, M., Sarnowski, C., Mägi, R., Nano, J., Gieger, C., Trompet, S., Lecoeur, C., Preuss, M. H. & 30 others, Prins, B. P., Guo, X., Bielak, L. F., Below, J. E., Bowden, D. W., Chambers, J. C., Kim, Y. J., Ng, M. C. Y., Petty, L. E., Sim, X., Zhang, W., Bennett, A. J., Bork-Jensen, J., Brummett, C. M., Canouil, M., Ec kardt, K. U., Fischer, K., Kardia, S. L. R., Kronenberg, F., Läll, K., Liu, C. T., Locke, A. E., Luan, J., Ntalla, I., Nylander, V., Schönherr, S., Schurmann, C., Morris, A. D., Palmer, C. N. A. & McCarthy, M. I., 8 Oct 2018, In : Nature Genetics. 50, 11, p. 1505-1513 9 p.

Research output: Contribution to journalArticle

170 Citations (Scopus)

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 31 others, Flannick, J., Grarup, N., Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Smith, A. V., An, P., Ligthart, S., Gustafsson, S., Malerba, G., Demirkan, A., Tajes, J. F., Steinthorsdottir, V., Wuttke, M., Lecoeur, C., Preuss, M., Bielak, L. F., Graff, M., Highland, H. M., Morris, A. D., Smith, B. H., Palmer, C. N. A. & ExomeBP Consortium, 9 Apr 2018, In : Nature Genetics. 50, 4, p. 559-571 13 p.

Research output: Contribution to journalArticle

Open Access
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82 Citations (Scopus)
256 Downloads (Pure)
2019

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

Flannick, J., Mercader, J. M., Fuchsberger, C., Udler, M. S., Mahajan, A., Wessel, J., Teslovich, T. M., Caulkins, L., Koesterer, R., Barajas-Olmos, F., Blackwell, T. W., Boerwinkle, E., Brody, J. A., Centeno-Cruz, F., Chen, L., Chen, S., Contreras-Cubas, C., Córdova, E., Correa, A., Cortes, M. & 30 others, DeFronzo, R. A., Dolan, L., Drews, K. L., Elliott, A., Floyd, J. S., Gabriel, S., Garay-Sevilla, M. E., García-Ortiz, H., Gross, M., Han, S., Heard-Costa, N. L., Jackson, A. U., Jørgensen, M. E., Kang, H. M., Kelsey, M., Kim, B-J., Koistinen, H. A., Kuusisto, J., Leader, J. B., Linneberg, A., Liu, C-T., Liu, J., Lyssenko, V., Manning, A. K., Marcketta, A., Malacara-Hernandez, J. M., Morris, A. D., Palmer, C. N. A., Scott, L. J. & Morris, A. P., Jun 2019, In : Nature. 570, 7759, p. 71-76 6 p.

Research output: Contribution to journalArticle

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34 Citations (Scopus)
89 Downloads (Pure)
2018

Pharmacogenetics of inhaled long-acting beta2-agonists in asthma: a systematic review

Slob, E. M. A., Vijverberg, S. J. H., Palmer, C. N. A., Zazuli, Z., Farzan, N., Oliveri, N. M. B., Pijnenburg, M. W., Koppelman, G. H. & Maitland van der Zee, A. H., Nov 2018, In : Pediatric Allergy and Immunology. 29, 7, p. 705-714 10 p.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
189 Downloads (Pure)
2016

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

Postmus, I., Warren, H. R., Trompet, S., Arsenault, B. J., Avery, C. L., Bis, J. C., Chasman, D. I., de Keyser, C. E., Deshmukh, H. A., Evans, D. S., Feng, Q., Li, X., Smit, R. A. J., Smith, A. V., Sun, F., Taylor, K. D., Arnold, A. M., Barnes, M. R., Barratt, B. J., Betteridge, J. & 68 others, Boekholdt, S. M., Boerwinkle, E., Buckley, B. M., Chen, Y-D. I., de Craen, A. J. M., Cummings, S. R., Denny, J. C., Dubé, M. P., Durrington, P. N., Eiriksdottir, G., Ford, I., Guo, X., Harris, T. B., Heckbert, S. R., Hofman, A., Hovingh, G. K., Kastelein, J. J. P., Launer, L. J., Liu, C-T., Liu, Y., Lumley, T., McKeigue, P. M., Munroe, P. B., Neil, A., Nickerson, D. A., Nyberg, F., O'Brien, E., O'Donnell, C. J., Post, W., Poulter, N., Vasan, R. S., Rice, K., Rich, S. S., Rivadeneira, F., Sattar, N., Sever, P., Shaw-Hawkins, S., Shields, D. C., Slagboom, P. E., Smith, N. L., Smith, J. D., Sotoodehnia, N., Stanton, A., Stott, D. J., Stricker, B. H., Stürmer, T., Uitterlinden, A. G., Wei, W-Q., Westendorp, R. G. J., Whitsel, E. A., Wiggins, K. L., Wilke, R. A., Ballantyne, C. M., Colhoun, H. M., Cupples, L. A., Franco, O. H., Gudnason, V., Hitman, G., Palmer, C. N. A., Psaty, B. M., Ridker, P. M., Stafford, J. M., Stein, C. M., Tardif, J-C., Caulfield, M. J., Jukema, J. W., Rotter, J. I. & Krauss, R. M., Dec 2016, In : Journal of Medical Genetics. 53, 12, p. 835-845 11 p.

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19 Citations (Scopus)
136 Downloads (Pure)
2017

Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

Tragante, V., Gho, J. M. I. H., Felix, J. F., Vasan, R. S., Smith, N. L., Voight, B. F., Palmer, C., van der Harst, P., Moore, J. H., Asselbergs, F. W. & CHARGE Heart Failure Working Group, 26 May 2017, In : BioData Mining. 10, p. 1-11 11 p., 18.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
143 Downloads (Pure)

Quantifying the extent to which index event biases influence large genetic association studies

Yaghootkar, H., Bancks, M. P., Jones, S. E., McDaid, A., Beaumont, R., Donnelly, L., Wood, A. R., Campbell, A., Tyrrell, J., Hocking, L. J., Tuke, M. A., Ruth, K. S., Pearson, E. R., Murray, A., Freathy, R. M., Munroe, P. B., Hayward, C., Palmer, C., Weedon, M. N., Pankow, J. S. & 2 others, Frayling, T. M. & Kutalik, Z., 1 Jun 2017, In : Human Molecular Genetics. 26, 5, p. 1018-1030 13 p.

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13 Citations (Scopus)
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2016

Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease

Yaghootkar, H., Lotta, L. A., Tyrrell, J., Smit, R. A. J., Jones, S. E., Donnelly, L., Beaumont, R., Campbell, A., Tuke, M. A., Hayward, C., Ruth, K. S., Padmanabhan, S., Jukema, J. W., Palmer, C. C., Hattersley, A., Freathy, R. M., Langenberg, C., Wareham, N. J., Wood, A. R., Murray, A. & 5 others, Weedon, M. N., Sattar, N., Pearson, E., Scott, R. A. & Frayling, T. M., Aug 2016, In : Diabetes. 65, 8, p. 2448-2460 13 p.

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44 Citations (Scopus)
178 Downloads (Pure)

Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12

Jackson, V. E., Ntalla, I., Sayers, I., Morris, R., Whincup, P., Casas, J-P., Amuzu, A., Choi, M., Dale, C., Kumari, M., Engmann, J., Kalsheker, N., Chappell, S., Guetta-Baranes, T., McKeever, T. M., Palmer, C. N. A., Tavendale, R., Holloway, J. W., Sayer, A. A., Dennison, E. M. & 20 others, Cooper, C., Bafadhel, M., Barker, B., Brightling, C., Bolton, C. E., John, M. E., Parker, S. G., Moffat, M. F., Wardlaw, A. J., Connolly, M. J., Porteous, D. J., Smith, B. H., Padmanabhan, S., Hocking, L., Stirrups, K. E., Deloukas, P., Strachan, D. P., Hall, I. P., Tobin, M. D. & Wain, L. V., Jun 2016, In : Thorax. 71, 6, p. 501-509 9 p.

Research output: Contribution to journalArticle

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13 Citations (Scopus)
115 Downloads (Pure)
2020

The effect of LRRK2 loss-of-function variants in humans

Whiffin, N., Armean, I. M., Kleinman, A., Marshall, J. L., Minikel, E. V., Goodrich, J. K., Quaife, N. M., Cole, J. B., Wang, Q., Karczewski, K. J., Cummings, B. B., Francioli, L., Laricchia, K., Guan, A., Alipanahi, B., Morrison, P., Baptista, M. A. S., Merchant, K. M., Ware, J. S., Havulinna, A. S. & 18 others, Iliadou, B., Lee, J-J., Nadkarni, G. N., Whiteman, C., 23andMe Research Team, Daly, M., Esko, T., Hultman, C., Loos, R. J. F., Milani, L., Palotie, A., Pato, C., Pato, M., Saleheen, D., Sullivan, P. F., Alföldi, J., Cannon, P. & MacArthur, D. G., 27 May 2020, In : Nature Medicine. 21 p.

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2 Citations (Scopus)
13 Downloads (Pure)

Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction

Meakin, P. J., Coull, B. M., Tuharska, Z., McCaffery, C., Akoumianakis, I., Antoniades, C., Brown, J., Griffin, K. J., Platt, F., Ozber, C. H., Yuldasheva, N. Y., Makava, N., Skromna, A., Prescott, A. R., McNeilly, A. D., Siddiqui, M. K., Palmer, C. N. A., Khan, F. & Ashford, M. L. J., 14 May 2020, In : Journal of Clinical Investigation. 15 p.

Research output: Contribution to journalArticle

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Filaggrin gene defects are associated with eczema, wheeze, and nasal disease during infancy: Prospective study

Basu, K., Inglis, S. K., Bremner, S. A., Ramsay, R., Abd, A., Rabe, H., Strange, E., Phillips, V., Seddon, P., Tavendale, R., Memon, A., Palmer, C. N. A., Fidler, K. & Mukhopadhyay, S., 27 Apr 2020, In : Journal of Allergy and Clinical Immunology. 2 p.

Research output: Contribution to journalLetter

Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker–Induced Angioedema

Maroteau, C., Siddiqui, M. K., Veluchamy, A., Carr, F., White, M., Cassidy, A. J., Rasmussen, E. R., Baranova, E. V., Eriksson, N., Bloch, K. M., Brown, N. J., Bygum, A., Hallberg, P., Karawajczyk, M., Magnusson, P. K. E., Yue, Q-Y., Syvänen, A-C., von Buchwald, C., Alfirevic, A., Maitland-van der Zee, A. H. & 3 others, Wadelius, M., Palmer, C. N. A. & PREDICTION-ADR Consortium, 4 Jun 2020, In : Clinical Pharmacology and Therapeutics. 8 p.

Research output: Contribution to journalArticle

Open Access
2016

CYP2C8 and SLCO1B1 variants and therapeutic response to thiazolidinediones in patients with type 2 diabetes.

Dawed, A. Y., Donnelly, L., Tavendale, R., Carr, F., Leese, G., Palmer, C. N. A., Pearson, E. & Zhou, K., Nov 2016, In : Diabetes Care. 39, 11, p. 1902-1908 7 p.

Research output: Contribution to journalArticle

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24 Citations (Scopus)
199 Downloads (Pure)
2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T. & 40 others, Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Aben, K. K., Alam, D. S., Alharthi, S. E., Allison, M., Amouyel, P., Asselbergs, F. W., Auer, P. L., Balkau, B., Campbell, P. T., Davies, G., Evangelou, E., Li, J., Mitchell, P., Morris, A. D., Palmer, C. N. A., Roberts, D. J., Smith, A. V., Wood, A. R., CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, EPIC-InterAct Consortium, INTERVAL Study, ReproGen Consortium, T2D-Genes Consortium, The MAGIC Investigators & Understanding Society Scientific Group, May 2018, In : Nature Genetics. 50, 5, p. 766-767 2 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T. & 40 others, Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Aben, K. K., Alam, D. S., Alharthi, S. E., Allison, M., Amouyel, P., Asselbergs, F. W., Auer, P. L., Balkau, B., Campbell, P. T., Davies, G., Evangelou, E., Li, J., Mitchell, P., Morris, A. P., Palmer, C. N. A., Roberts, D. J., Smith, A. V., Wood, A. R., CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, EPIC-InterAct Consortium, INTERVAL Study, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators & Understanding Society Scientific Group, May 2018, In : Nature Genetics. 50, 5, p. 765-766 2 p.

Research output: Contribution to journalArticle

2016

The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis

Robinson, P. C., Leo, P. J., Pointon, J. J., Harris, J., Cremin, K., Bradbury, L. A., Wellcome Trust Case Control Consortium, Australasian Osteoporosis Genetics Consortium AOGC, Stebbings, S., Harrison, A. A., Evans, D. M., Duncan, E. L., Wordsworth, B. P. & Brown, M. A., Jan 2016, In : Genes and Immunity. 17, 1, p. 46-51 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2019

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Romagnoni, A., Jégou, S., Van Steen, K., Wainrib, G. & Hugot, J-P., 17 Jul 2019, In : Scientific Reports. 9, 1, p. 1-18 18 p., 10351.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
57 Downloads (Pure)
2020
Open Access
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1 Citation (Scopus)
5 Downloads (Pure)
2017

Early HTA in Pharmacogenomics: A Case Example in Cardiovascular Drugs

Baranova, E. V., Geenen, J. W., Asselbergs, F. W., Palmer, C. N., de Boer, A., Maitland-van der Zee, A-H. & Hövels, A. M., Aug 2017, In : Pharmacoepidemiology and Drug Safety. 26, S2, p. 264-265 2 p., 436.

Research output: Contribution to journalMeeting abstract

Genetic variation in Kruppel like factor 15 is associated with left ventricular hypertrophy in patients with type 2 diabetes: discovery and replication cohorts

Patel, S. K., Wai, B., Lang, C. C., Levin, D., Palmer, C. N. A., Parry, H. M., Velkoska, E., Harrap, S. B., Srivastava, P. M. & Burrell, L. M., Apr 2017, In : EBioMedicine. 18, p. 171-178 8 p.

Research output: Contribution to journalArticle

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7 Citations (Scopus)
69 Downloads (Pure)

Homozygous status for the Arg16 variant is associated with increased prescribing of controller asthma medication and increased asthma-related prescribing cost

Soares, P., Fidler, K., Tavendale, R., Turner, S., Lipworth, B., Bremner, S., Palmer, C. N. A. & Mukhopadhyay, S., Dec 2017, In : Clinical and Experimental Allergy. 47, 12, p. 1681-1682 2 p., O.010.

Research output: Contribution to journalMeeting abstract

2016

Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis

Ahmadizar, F., Vijverberg, S. J. H., Arets, H. G. M., de Boer, A., Lang, J. E., Kattan, M., Palmer, C. N. A., Mukhopadhyay, S., Turner, S. & Maitland-van der Zee, A. H., 30 Sep 2016, In : European Respiratory Journal. 48, 4, p. 1063-1073 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2017

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

Wain, L. V., Vaez, A., Jansen, R., Joehanes, R., van der Most, P. J., Erzurumluoglu, A. M., O’Reilly, P. F., Cabrera, C. P., Warren, H. R., Rose, L. M., Verwoert, G. C., Hottenga, J. J., Strawbridge, R. J., Esko, T., Arking, D. E., Hwang, S-J., Guo, X., Kutalik, Z., Trompet, S., Shrine, N. R. G. & 223 others, Teumer, A., Ried, J. S., Bis, J. C., Smith, A. V., Amin, N., Nolte, I. M., Lyytikäinen, L-P., Mahajan, A., Wareham, N. J., Hofer, E., Joshi, P. K., Kristiansson, K., Traglia, M., Havulinna, A. S., Goel, A., Nalls, M. A., Sõber, S., Vuckovic, D., Luan, J., Del Greco M., F., Ayers, K. L., Marrugat, J., Ruggiero, D., Lopez, L. M., Niiranen, T., Enroth, S., Jackson, A. U., Nelson, C. P., Huffman, J. E., Zhang, W., Marten, J., Gandin, I., Harris, S. E., Zemunik, T., Lu, Y., Evangelou, E., Shah, N., De Borst, M. H., Mangino, M., Prins, B. P., Campbell, A., Li-Gao, R., Chauhan, G., Oldmeadow, C., Abecasis, G. R., Abedi, M., Barbieri, C. M., Barnes, M. R., Batini, C., Beilby, J. P., Blake, T., Boehnke, M., Bottinger, E. P., Braund, P. S., Brown, M. J., Brumat, M., Campbell, H., Chambers, J. C., Cocca, M., Collins, F. S., Connell, J., Cordell, H. J., Damman, J. J., Davies, G., de Geus, E. J. C., de Mutsert, R., Deelen, J., Demirkale, Y., Doney, A. S. F., Dörr, M., Farrall, M., Ferreira, T., Frånberg, M., Gao, H., Giedraitis, V., Gieger, C., Giulianini, F., Gow, A. J., Hamsten, A., Harris, T. B., Hofman, A., Holliday, E. G., Hui, J., Jarvelin, M-R., Johansson, Å., Johnson, A. D., Jousilahti, P. R., Jula, A., Kähönen, M., Kathiresan, S., Khaw, K-T., Kolcic, I., Koskinen, S., Langenberg, C., Larson, M., Launer, L. J., Lehne, B., Liewald, D. C. M., Lin, L-A., Lind, L., Mach, F., Mamasoula, C., Menni, C., Mifsud, B., Aulchenko, Y., Morgan, A., Morris, A. D., Morrison, A. C., Munson, P. J., Nandakumar, P., Nguyen, Q. T., Nutile, T., Oldehinkel, A. J., Oostra, B. A., Org, E., Padmanabhan, S., Palotie, A., Paré, G., Pattie, A., Penninx, B. W. J. H., Poulter, N. R., Pramstaller, P. P., Raitakari, O. T., Ren, M., Rice, K., Ridker, P. M., Riese, H., Ripatti, S., Robino, A., Rotter, J. I., Rudan, I., Saba, Y., Saint Pierre, A., Sala, C. F., Sarin, A-P., Schmidt, R., Scott, R. J., Seelen, M. A. J., Shields, D. C., Siscovick, D. S., Sorice, R., Stanton, A., Stott, D. J., Sundström, J., Swertz, M. A., Taylor, K. D., Thom, S., Tzoulaki, I., Tzourio, C., Uitterlinden, A. G., Völker, U., Vollenweider, P., Wild, S. H., Willemsen, G., Wright, A. F., Yao, J., Thériault, S., Conen, D., Attia, J. R., Sever, P., Debette, S., Mook-Kanamori, D. O., Zeggini, E., Spector, T. D., van der Harst, P., Palmer, C. N. A., Vergnaud, A-C., Loos, R. J. F., Polasek, O., Starr, J. M., Girotto, G., Hayward, C., Kooner, J. S., Lindgren, C. M., Vitart, V., Samani, N. J., Tuomilehto, J., Gyllensten, U. B., Knekt, P., Deary, I. J., Ciullo, M., Elosua, R., Keavney, B. D., Hicks, A. A., Scott, R. A., Gasparini, P., Laan, M., Liu, Y., Watkins, H., Hartman, C. A., Salomaa, V., Toniolo, D., Perola, M., Wilson, J. F., Schmidt, H., Zhao, J. H., Lehtimäki, T., van Duijn, C. M., Gudnason, V., Psaty, B. M., Peters, A., Rettig, R., James, A. L., Jukema, J. W., Strachan, D. P., Palmas, W., Metspalu, A., Ingelsson, E., Boomsma, D. I., Franco, O. H., Bochud, M., Newton-Cheh, C., Munroe, P. B., Elliott, P., Chasman, D. I., Chakravarti, A., Knight, J., Morris, A. P., Levy, D., Tobin, M. D., Snieder, H., Caulfield, M. J. & Ehret, G. B., 24 Jul 2017, In : Hypertension. 70, 3, p. e4-e19 16 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
2019

Association of Chromosome 9p21 with Subsequent Coronary Heart Disease events: A GENIUS-CHD study of individual participant data

CARDIoGRAMplusC4D Consortium, Patel, R. S., Schmidt, A. F., Tragante, V., McCubrey, R. O., Holmes, M. V., Howe, L. J., Direk, K., Åkerblom, A., Leander, K., Virani, S. S., Kaminski, K. A., Muehlschlegel, J. D., Dubé, M. P., Allayee, H., Almgren, P., Alver, M., Baranova, E. V., Behlouli, H., Boeckx, B. & 31 others, Braund, P. S., Breitling, L. P., Delgado, G., Duarte, N. E., Dufresne, L., Eriksson, N., Foco, L., Gijsberts, C. M., Gong, Y., Hartiala, J., Heydarpour, M., Hubacek, J. A., Kleber, M., Kofink, D., Kuukasjärvi, P., Lee, V. V., Leiherer, A., Lenzini, P. A., Levin, D., Lyytikäinen, L. P., Martinelli, N., Mons, U., Nelson, C. P., Nikus, K., Pilbrow, A. P., Ploski, R., Sun, Y. V., Tanck, M. W. T., Mordi, I. R., Palmer, C. N. & Lang, C. C., Apr 2019, In : Circulation: Genomic and Precision Medicine. 12, 4, p. 161-172 12 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
5 Downloads (Pure)

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

Noordam, R., Young, W. J., Salman, R., Kanters, J. K., van den Berg, M. E., van Heemst, D., Lin, H. J., Barreto, S. M., Biggs, M. L., Biino, G., Catamo, E., Concas, M. P., Ding, J., Evans, D. S., Foco, L., Grarup, N., Lyytikäinen, L. P., Mangino, M., Mei, H., van der Most, P. J. & 83 others, Müller-Nurasyid, M., Nelson, C. P., Qian, Y., Repetto, L., Said, M. A., Shah, N., Schramm, K., Vidigal, P. G., Weiss, S., Yao, J., Zilhao, N. R., Brody, J. A., Braund, P. S., Brumat, M., Campana, E., Christofidou, P., Caulfield, M. J., De Grandi, A., Dominiczak, A. F., Doney, A. S. F., Eiriksdottir, G., Ellervik, C., Giatti, L., Gögele, M., Graff, C., Guo, X., van der Harst, P., Joshi, P. K., Kähönen, M., Kestenbaum, B., Lima-Costa, M. F., Linneberg, A., Maan, A. C., Meitinger, T., Padmanabhan, S., Pattaro, C., Peters, A., Petersmann, A., Sever, P., Sinner, M. F., Shen, X., Stanton, A., Strauch, K., Soliman, E. Z., Tarasov, K. V., Taylor, K. D., Thio, C. H. L., Uitterlinden, A. G., Vaccargiu, S., Waldenberger, M., Robino, A., Correa, A., Cucca, F., Cummings, S. R., Dörr, M., Girotto, G., Gudnason, V., Hansen, T., Heckbert, S. R., Juhl, C. R., Kääb, S., Lehtimäki, T., Liu, Y., Lotufo, P. A., Palmer, C. N. A., Pirastu, M., Pramstaller, P. P., Ribeiro, A. L. P., Rotter, J. I., Samani, N. J., Snieder, H., Spector, T. D., Stricker, B. H., Verweij, N., Wilson, J. F., Wilson, J. G., Jukema, J. W., Tinker, A., Newton-Cheh, C. H., Sotoodehnia, N., Mook-Kanamori, D. O., Munroe, P. B. & Warren, H. R., 25 Jun 2019, In : Journal of the American College of Cardiology. 73, 24, p. 3118-3131 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 242 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., DePristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., Hrabé de Angelis, M., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Fowler, S. P., Arya, R., DeFronzo, R. A., Abboud, H. E., Syvänen, A-C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S-T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J-Y., Han, B-G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., Melander, O., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., Liu, J., Khor, C-C., Chia, K. S., Lim, W. Y., Cheng, C-Y., Chan, E., Tai, E. S., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Kravic, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Owen, K. R., Farmer, A. J., Frayling, T. M., O'Rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stančáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Kesaniemi, Y. A., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 2017, In : Diabetes. 66, 7, p. 2019-2032 14 p.

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