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  • Philip Cohen
2018

Ubiquitin chains as second messengers

Cohen, P., Apr 2018, In : Nature Reviews Molecular Cell Biology. 19, 4, 1 p., 212.

Research output: Contribution to journalComment/debate

2 Citations (Scopus)
2019
Open Access
1 Citation (Scopus)
2017

Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3

Zhang, J., Macartney, T., Peggie, M. & Cohen, P., 26 Jul 2017, In : Biochemical Journal. 474, 13, p. 2235-2248 16 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
149 Downloads (Pure)

Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β

Bakshi, S., Taylor, J., Strickson, S., Macartney, T. & Cohen, P., 15 Mar 2017, In : Biochemical Journal. 474, 7, p. 1163-1174 12 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
292 Downloads (Pure)
2018

ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism

Nanda, S. K., Nagamori, T., Windheim, M., Amu, S., Aviello, G., Patterson-Kane, J., Arthur, J. S. C., Ley, S. C., Fallon, P. & Cohen, P., 1 Dec 2018, In : Journal of Immunology. 201, 11, p. 3373-3382 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

The mechanism of activation of IRAK1 and IRAK4 by interleukin-1 and TollLike receptor agonists

Vollmer, S., Strickson, S., Zhang, T., Gray, N., Lee, K., Rao, V. & Cohen, P., 6 Jun 2017, In : Biochemical Journal. 474, 12, p. 2027-2038 12 p.

Research output: Contribution to journalArticle

Open Access
File
27 Citations (Scopus)
144 Downloads (Pure)
2016
Open Access
File
18 Citations (Scopus)
172 Downloads (Pure)

Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling.

Emmerich, C., Bakshi, S., Kelsall, I., Ortiz-Guerrero, J., Shpiro, N. & Cohen, P., 3 Jun 2016, In : Biochemical and Biophysical Research Communications. 474, 3, p. 452-461 10 p.

Research output: Contribution to journalArticle

Open Access
File
33 Citations (Scopus)
185 Downloads (Pure)
2019

Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

Odqvist, L., Jevnikar, Z., Riise, R., Öberg, L., Rhedin, M., Leonard, D., Yrlid, L., Jackson, S., Mattsson, J., Nanda, S., Cohen, P., Knebel, A., Arthur, S., Thörn, K., Svenungsson, E., Jönsen, A., Gunnarsson, I., Tandre, K., Alexsson, A., Kastbom, A. & 10 others, Rantapää-Dahlqvist, S., Eloranta, M-L., Syvänen, A-C., Bengtsson, A., Johansson, P., Sandling, J. K., Sjöwall, C., Rönnblom, L., Collins, B. & Vaarala, O., 1 Oct 2019, In : Annals of the Rheumatic Diseases. 78, 10, p. 1363-1370 8 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
284 Downloads (Pure)
Open Access
File
5 Citations (Scopus)
94 Downloads (Pure)

Distinct signals and immune cells drive liver pathology and glomerulonephritis in ABIN1[D485N] mice

Nanda, S. K., Petrova, T., Marchesi, F., Gierlinski, M., Razsolkov, M., Lee, K. L., Wright, S. W., Rao, V. R., Cohen, P. & Arthur, J. S. C., 1 Dec 2019, In : Life Science Alliance. 2, 6, 19 p., e201900533.

Research output: Contribution to journalArticle

Open Access
File
17 Downloads (Pure)
2017

The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways

Cohen, P. & Strickson, S., May 2017, In : Cell Death & Differentiation. 24, p. 1153-1159 7 p.

Research output: Contribution to journalReview article

Open Access
File
22 Citations (Scopus)
156 Downloads (Pure)
2018

The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation

Thomas, Y., Scott, D. C., Kristariyanto, Y. A., Rinehart, J., Clark, K., Cohen, P. & Kurz, T., 29 Jun 2018, In : PLoS ONE. 13, 6, p. 1-19 19 p., e0199197.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
106 Downloads (Pure)
2016

HCK is a survival determinant transactivated by mutated MYD88, and a direct target of ibrutinib

Yang, G., Buhrlage, S., Tan, L., Liu, X., Chen, J., Xu, L., Tsakmaklis, N., Chen, J. G., Patterson, C. J., Brown, J. R., Castillo, J. J., Zhang, W., Zhang, X., Liu, S., Cohen, P., Hunter, Z. R., Gray, N. S. & Treon, S. P., 23 Jun 2016, In : Blood. 127, 25, p. 3237-3252 16 p.

Research output: Contribution to journalArticle

Open Access
File
43 Citations (Scopus)
148 Downloads (Pure)
2017

Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling

Strickson, S., Emmerich, C. H., Goh, E. T. H., Zhang, J., Kelsall, I. R., Macartney, T., Hastie, C. J., Knebel, A., Peggie, M., Marchesi, F., Arthur, J. S. C. & Cohen, P., 25 Apr 2017, In : Proceedings of the National Academy of Sciences. 114, 7, p. E3481-E3489 9 p.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
162 Downloads (Pure)
2020

Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses

Hutchinson, L. D., Darling, N. J., Nicolaou, S., Gori, L., Squair, D. R., Cohen, P., Hill, C. S. & Sapkota, G. P., 22 Jan 2020, In : Cell Death and Disease. 11, p. 1-17 17 p., 49.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
44 Downloads (Pure)