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  • Michael Ferguson
2017

Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes

Ivanova, I. M., Nepogodiev, S. A., Saalbach, G., O'Neill, E. C., Urbaniak, M. D., Ferguson, M. A. J., Gurcha, S. S., Besra, G. S. & Field, R. A., 13 Jan 2017, In : Carbohydrate Research. 438, p. 26-38 13 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
130 Downloads (Pure)
2016

Proteomic identification of immunodiagnostic antigens for Trypanosoma vivax infections in cattle and generation of a proof-of-concept lateral flow test diagnostic device

Fleming, J. R., Sastry, L., Wall, S. J., Sullivan, L. & Ferguson, M. A. J., 8 Sep 2016, In : PLoS Neglected Tropical Diseases. 10, 9, 11 p., e0004977.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
165 Downloads (Pure)
2019

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Wyllie, S., Brand, S., Thomas, M., De Rycker, M., Chung, C-W., Peña, I., Bingham, R., Bueren-Calabuig, J., Cantizani, J., Cebrian, D., Craggs, P. D., Ferguson, L., Goswami, P., Hobrath, J., Howe, J., Jeacock, L., Ko, E. J., Korczynska, J., MacLean, L., Manthri, S. & 29 others, Santos Martinez, M., Mata-Cantero, L., Moniz, S., Nuhs, A., Osuna-Cabello, M., Pinto, E., Riley, J., Robinson, S., Rowland, P., Simeons, F., Shishikura, Y., Spinks, D., Stojanovski, L., Thomas, J., Thompson, S., Viayna Gaza, E., Wall, R., Zuccotto, F., Horn, D., Ferguson, M., Fairlamb, A., Fiandor, J. M., Martín, J., Gray, D., Miles, T. J., Gilbert, I., Read, K., Marco, M. & Wyatt, P., 7 May 2019, In : Proceedings of the National Academy of Sciences. 116, 19, p. 9318-9323 6 p., 201820175.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
134 Downloads (Pure)
2018

African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat

Pinger, J., Nešić, D., Ali, L., Aresta-Branco, F., Lilic, M., Chowdhury, S., Kim, H. S., Verdi, J., Raper, J., Ferguson, M. A. J., Papavasiliou, F. N. & Stebbins, C. E., Aug 2018, In : Nature Microbiology. 3, 8, p. 932-938 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
243 Downloads (Pure)
2017
Open Access
File
4 Citations (Scopus)
183 Downloads (Pure)
2020

Setting our sights on infectious diseases

De Rycker, M., Horn, D., Aldridge, B., Amewu, R. K., Barry, C. E., Buckner, F. S., Cook, S., Ferguson, M. A. J., Gobeau, N., Herrmann, J., Herrling, P., Hope, W., Keiser, J., Lafuente-Monasterio, M. J., Leeson, P. D., Leroy, D., Manjunatha, U. H., McCarthy, J., Miles, T. J., Mizrahi, V. & 17 others, Moshynets, O., Niles, J., Overington, J. P., Pottage, J., Rao, S. P. S., Read, K. D., Ribeiro, I., Silver, L. L., Southern, J., Spangenberg, T., Sundar, S., Taylor, C., Van Voorhis, W. C., White, N. J., Wyllie, S., Wyatt, P. G. & Gilbert, I. H., 10 Jan 2020, In : ACS Infectious Diseases. 6, p. 3-13 11 p.

Research output: Contribution to journalArticle

Open Access
File
60 Downloads (Pure)
2018

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Wyllie, S., Thomas, M., Patterson, S., Crouch, S., De Rycker, M., Lowe, R., Gresham, S., Urbaniak, M. D., Otto, T. D., Stojanovski, L., Simeons, F. R. C., Manthri, S., MacLean, L. M., Zuccotto, F., Homeyer, N., Pflaumer, H., Boesche, M., Sastry, L., Connolly, P., Albrecht, S. & 12 others, Berriman, M., Drewes, G., Gray, D. W., Ghidelli-Disse, S., Dixon, S., Fiandor, J. M., Wyatt, P. G., Ferguson, M. A. J., Fairlamb, A. H., Miles, T. J., Read, K. D. & Gilbert, I. H., 9 Aug 2018, In : Nature. 560, 7717, p. 192-197 6 p.

Research output: Contribution to journalArticle

Open Access
File
34 Citations (Scopus)
456 Downloads (Pure)
2019

Para-site-seeing: Departure Lounge: LifeSpace science art reserach gallery, University of Dundee

Floyd, A., Yeoman, H., Southern, J., Dillon, R., Cook, S., Fairlamb, A., Ferguson, M., Horn, D., MacLean, L., Manthri, S., Paterson, C., Pearson, L., Prescott, A., Read, K., Shastry, L., Svensen, N. & Thomas, J., 2019

Research output: Non-textual formExhibition

Reprogramming of Trypanosoma cruzi metabolism triggered by parasite interaction with the host cell extracellular matrix

Mattos, E. C., Canuto, G., Varón, N. C. M., Magalhães, R. D. M., Crozier, T. W. M., Lamont, D. J., Tavares, M. F. M., Colli, W., Ferguson, M. A. J. & Alves, M. J. M., 6 Feb 2019, In : PLoS Neglected Tropical Diseases. 13, 2, p. 1-27 27 p., e0007103.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
118 Downloads (Pure)
2017
Open Access
File
138 Citations (Scopus)
298 Downloads (Pure)
2019

Organizational innovation for developing new medicines that target aging and age-related conditions

Ford, G. A., Lord, J. M., Ferguson, M. A. J., Bountra, C. & Le Couteur, D. G., 6 Mar 2019, In : The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 75, 1, p. 87-88 2 p., glz062.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
142 Downloads (Pure)
2016

Global membrane protein interactome analysis using in vivo crosslinking and MS-based protein correlation profiling

Larance, M., Kirkwood, K. J., Tinti, M., Brenes Murillo, A., Ferguson, M. & Lamond, A., 1 Jul 2016, In : Molecular & Cellular Proteomics. 15, 7, p. 2476-2490 15 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
125 Downloads (Pure)
2018

Gluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei

Kovarova, J., Nagar, R., Correia Faria, J., Ferguson, M., Barrett, M. P. & Horn, D., 27 Dec 2018, In : PLoS Pathogens. 14, 12, p. 1-22 22 p., e1007475.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
109 Downloads (Pure)

N-glycan microheterogeneity regulates interactions of plasma proteins

Wu, D., Struwe, W. B., Harvey, D. J., Ferguson, M. A. J. & Robinson, C. V., 28 Aug 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 35, p. 8763-8768 6 p., 201807439.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
127 Downloads (Pure)
2019
Open Access
File
9 Citations (Scopus)
174 Downloads (Pure)
2020

A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor

Raimi, O., Hurtado-Guerrero, R., Borodkin, V., Ferenbach, A., Urbaniak, M., Ferguson, M. & van Aalten, D., 1 Apr 2020, In : RSC Chemical Biology. 1, p. 13-25 13 p.

Research output: Contribution to journalArticle

CAP-MAP: cap analysis protocol with minimal analyte processing, a rapid and sensitive approach to analysing mRNA cap structures

Galloway, A., Atrih, A., Grzela, R., Darzynkiewicz, E., Ferguson, M. A. J. & Cowling, V. H., 26 Feb 2020, In : Open Biology. 10, 2, p. 1-13 13 p., 190306.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
40 Downloads (Pure)
2018

Proteomic analysis of the cell cycle of procylic form Trypanosoma brucei

Crozier, T. W. M., Tinti, M., Wheeler, R. J., Ly, T., Ferguson, M. A. J. & Lamond, A. I., 1 Jun 2018, In : Molecular & Cellular Proteomics. 17, 6, p. 1184-1195 12 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
138 Downloads (Pure)

The mRNA cap methyltransferase gene TbCMT1 is not essential in vitro but is a virulence factor in vivo for bloodstream form Trypanosoma brucei

Kelner, A., Tinti, M., Guther, M., Foth, B. J., Chappell, L., Berriman, M., Cowling, V. & Ferguson, M., 24 Jul 2018, In : PLoS ONE. 13, 7, p. 1-14 14 p., e0201263.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
123 Downloads (Pure)
2019
Open Access
File
1 Citation (Scopus)
68 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
86 Downloads (Pure)
2017

Prediction of protein complexes in Trypanosoma brucei by protein correlation profiling mass spectrometry and machine learning

Crozier, T. W. M., Tinti, M., Larance, M., Lamond, A. I. & Ferguson, M. A. J., 1 Dec 2017, In : Molecular & Cellular Proteomics. 16, 12, p. 2254-2267 14 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
171 Downloads (Pure)
2016

A gene of the β3-glycosyltransferase family encodes N-acetylglucosaminyltransferase II function in Trypanosoma brucei

Damerow, M., Graalfs, F., Guther, M. L. S., Mehlert, A., Izquierdo, L. & Ferguson, M. A. J., 24 Jun 2016, In : Journal of Biological Chemistry. 291, 26, p. 13834-13845 12 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
150 Downloads (Pure)
2017

Genetic Metabolic Complementation establishes a requirement for GDP-fucose in Leishmania

Guo, H., Novozhilova, N. M., Bandini, G., Turco, S. J., Ferguson, M. A. J. & Beverley, S. M., 23 Jun 2017, In : Journal of Biological Chemistry. 292, 25, p. 10696-10708 13 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
122 Downloads (Pure)
2016

Evaluation of antigens for development of a serological test for Human African Trypanosomiasis

Biéler, S., Waltenberger, H., Barrett, M. P., McCulloch, R., Mottram, J. C., Carrington, M., Schwaeble, W., McKerrow, J., Phillips, M. A., Michels, P. A., Büscher, P., Sanchez, J-C., Bishop, R., Robinson, D. R., Bangs, J., Ferguson, M., Nerima, B., Albertini, A., Michel, G., Radwandska, M. & 1 others, Ndung'u, J. M., 9 Dec 2016, In : PLoS ONE. 11, 12, p. 1-23 23 p., e0168074.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
309 Downloads (Pure)
2020

Treating age-related multimorbidity: the drug discovery challenge

Ermogenous, C., Green, C., Jackson, T., Ferguson, M. & Lord, J. M., 20 Jun 2020, In : Drug Discovery Today. 13 p.

Research output: Contribution to journalReview article

Open Access