Find Research Outputs

Search in all content

Filters for Research Outputs

Search concepts
Selected filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Angus Lamond
2017

Common genetic variation drives molecular heterogeneity in human iPSCs

Kilpinen, H., Goncalves, A., Leha, A., Afzal, V., Alasoo, K., Ashford, S., Bala, S., Bensaddek, D., Casale, F. P., Culley, O. J., Danecek, P., Faulconbridge, A., Harrison, P. W., Kathuria, A., McCarthy, D. J., McCarthy, S. A., Meleckyte, R., Memari, Y., Moens, N., Soares, F. & 23 others, Mann, A., Streeter, I., Agu, C. A., Alderton, A., Nelson, R., Harper, S., Patel, M., White, A., Patel, S. R., Clarke, L., Halai, R., Kirton, C. M., Kolb-Kokocinski, A., Beales, P. L., Birney, E., Danovi, D., Lamond, A. I., Ouwehand, W. H., Vallier, L., Watt, F. M., Durbin, R., Stegle, O. & Gaffney, D. J., 15 Jun 2017, In : Nature. 546, 7658, p. 370-375 6 p.

Research output: Contribution to journalArticle

Open Access
File
137 Citations (Scopus)
152 Downloads (Pure)
2013

Analysis of human protein replacement stable cell lines established using snoMEN-PR vector

Ono, M., Yamada, K., Endo, A., Avolio, F. & Lamond, A. I., 25 Apr 2013, In : PLoS ONE. 8, 4, 12 p., e62305.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
115 Downloads (Pure)
2011

Mass spectrometry-based immuno-precipitation proteomics - The user's guide

ten Have, S., Boulon, S., Ahmad, Y. & Lamond, A. I., Mar 2011, In : Proteomics. 11, 6, p. 1153-1159 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Nuclear Speckles

Spector, D. L. & Lamond, A. I., Feb 2011, In : Cold spring harbor perspectives in biology. 3, 2, p. - 12 p., a000646.

Research output: Contribution to journalArticle

371 Citations (Scopus)

An intranucleolar body associated with rDNA

Hutten, S., Prescott, A., James, J., Riesenberg, S., Boulon, S., Lam, Y. W. & Lamond, A. I., Oct 2011, In : Chromosoma. 120, 5, p. 481-499 19 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2014

Identification of small molecule inhibitors of pre-mRNA splicing

Pawellek, A., McElroy, S., Samatov, T., Mitchell, L., Woodland, A., Ryder, U., Gray, D., Lührmann, R. & Lamond, A. I., 12 Dec 2014, In : Journal of Biological Chemistry. 289, 50, p. 34683-34698 16 p.

Research output: Contribution to journalArticle

Open Access
File
38 Citations (Scopus)
256 Downloads (Pure)
2013

Characterization of Native Protein Complexes and Protein Isoform Variation Using Size-fractionation-based Quantitative Proteomics

Kirkwood, K. J., Ahmad, Y., Larance, M. & Lamond, A. I., 1 Dec 2013, In : Molecular & Cellular Proteomics. 12, 12, p. 3851-3873 23 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
2012

Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization

Ahmad, Y., Boisvert, F-M., Lundberg, E., Uhlen, M. & Lamond, A. I., 1 Mar 2012, In : Molecular & Cellular Proteomics. 11, 3

Research output: Contribution to journalArticle

37 Citations (Scopus)
2015

Global proteomics analysis of the response to starvation in C. elegans

Larance, M., Pourkarimi, E., Wang, B., Brenes Murillo, A., Kent, R., Lamond, A. I. & Gartner, A., 1 Jul 2015, In : Molecular & Cellular Proteomics. 14, 7, p. 1989-2001 13 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
169 Downloads (Pure)
2016

Analysis of mass spectrometry data for nucleolar proteomics experiments

Nicolas, A., Bensaddek, D. & Lamond, A. I., 2016, The nucleolus: methods and protocols. Németh, A. (ed.). New York: Springer , p. 263-276 14 p. (Methods in molecular biology; vol. 1455).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

2013

Modulation of higher order chromatin conformation in mammalian cell nuclei can be mediated by polyamines and divalent cations

Visvanathan, A., Ahmed, K., Even-Faitelson, L., Lleres, D., Bazett-Jones, D. P. & Lamond, A. I., 2013, In : PLoS ONE. 8, 6, 16 p., e67689.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2017

The chromatin assembly factor complex 1 (CAF1) and 5-Azacytidine (5-AzaC) affect cell motility in Src-transformed human epithelial cells

Endo, A., Ly, T., Pippa, R., Bensaddek, D., Nicolas, A. & Lamond, A. I., 6 Jan 2017, In : Journal of Biological Chemistry. 292, 1, p. 172-184 13 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
195 Downloads (Pure)
2016

The histone chaperone Vps75 forms multiple oligomeric assemblies capable of mediating exchange between histone H3–H4 tetramers and Asf1–H3–H4 complexes

Hammond, C. M., Sundaramoorthy, R., Larance, M., Lamond, A., Stevens, M. A., El-Mkami, H., Norman, D. & Owen-Hughes, T., 27 Jul 2016, In : Nucleic Acids Research. 44, 13, p. 6157-6172 16 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
250 Downloads (Pure)
2019

The Encyclopedia of Proteome Dynamics: The KinoViewer

Brenes Murillo, A. & Lamond, A., 15 Apr 2019, In : Bioinformatics. 35, 8, p. 1441-1442 2 p., bty823.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
93 Downloads (Pure)
2020

Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes

McCarthy, D. J., Rostom, R., Huang, Y., Kunz, D. J., Danecek, P., Bonder, M. J., Hagai, T., Lyu, R., Wang, W., Gaffney, D. J., Simons, B. D., Stegle, O. & Teichmann, S. A., 16 Mar 2020, In : Nature Methods. 17, 4, p. 414-421 8 p.

Research output: Contribution to journalArticle

2011

Identification of human miRNA precursors that resemble box C/D snoRNAs

Ono, M., Scott, M. S., Yamada, K., Avolio, F., Barton, G. J. & Lamond, A. I., May 2011, In : Nucleic Acids Research. 39, 9, p. 3879-3891 13 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)
2019

Composition of the Survival Motor Neuron (SMN) complex in Drosophila melanogaster

Matera, A. G., Raimer, A. C., Schmidt, C. A., Kelly, J. A., Droby, G. N., Baillat, D., Ten Have, S., Lamond, A. I., Wagner, E. J. & Gray, K. M., 1 Feb 2019, In : G3 : Genes, Genomes, Genetics. 9, 2, p. 491-503 13 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
130 Downloads (Pure)

Multi-batch TMT reveals false positives, batch effects and missing values

Brenes Murillo, A., Hukelmann, J., Bensaddek, D. & Lamond, A., 1 Oct 2019, In : Molecular and Cellular Proteomics. 18, 10, p. 1967-1980 14 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
10 Downloads (Pure)
2016

The cytotoxic T cell proteome and its shaping by the kinase mTOR

Hukelmann, J. L., Anderson, K. E., Sinclair, L. V., Grzes, K. M., Brenes Murillo, A., Hawkins, P. T., Stephens, L. R., Lamond, A. I. & Cantrell, D. A., Jan 2016, In : Nature Immunology. 17, 1, p. 104-112 9 p.

Research output: Contribution to journalArticle

Open Access
File
85 Citations (Scopus)
220 Downloads (Pure)

Deep Proteome Analysis Identifies Age-Related Processes in C. elegans

Narayan, V., Ly, T., Pourkarimi, E., Brenes Murillo, A., Gartner, A., Lamond, A. & Kenyon, C., 24 Aug 2016, In : Cell Systems. 3, 2, p. 144-159 15 p.

Research output: Contribution to journalArticle

Open Access
File
34 Citations (Scopus)
287 Downloads (Pure)
2019

EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

Elias, M. S., Wright, S. C., Remenyi, J., Abbott, J. C., Bray, S. E., Cole, C., Edwards, S., Gierlinski, M., Glok, M., McGrath, J. A., Nicholson, W. V., Paternoster, L., Prescott, A. R., Have, S. T., Whitfield, P. D., Lamond, A. I. & Brown, S. J., Aug 2019, In : Journal of Allergy and Clinical Immunology. 144, 2, p. 470-481 12 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
10 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
71 Downloads (Pure)
2014

Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control

Bizarro, J., Charron, C., Boulon, S., Westman, B., Pradet-Balade, B., Vandermoere, F., Chagot, M-E., Hallais, M., Ahmad, Y., Leonhardt, H., Lamond, A., Manival, X., Branlant, C., Charpentier, B., Verheggen, C. & Bertrand, E., 24 Nov 2014, In : Journal of Cell Biology. 207, 4, p. 463-480 18 p.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
256 Downloads (Pure)
2017

Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation

Hiraga, S., Ly, T., Garzón, J., Hořejší, Z., Ohkubo, Y., Endo, A., Obuse, C., Boulton, S. J., Lamond, A. & Donaldson, A. D., 1 Mar 2017, In : EMBO Reports. 18, 3, p. 403-419 17 p.

Research output: Contribution to journalArticle

Open Access
File
44 Citations (Scopus)
130 Downloads (Pure)
2012

The adenomatous polyposis Coli protein contributes to normal compaction of mitotic chromatin

Dikovskaya, D., Khoudoli, G., Newton, I. P., Chadha, G. S., Klotz, D., Visvanathan, A., Lamond, A., Swedlow, J. R. & Nathke, I. S., 2012, In : PLoS ONE. 7, 6, e38102.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2014

A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells

Ly, T., Ahmad, Y., Shlien, A., Soroka, D., Mills, A., Emanuele, M. J., Stratton, M. R. & Lamond, A. I., 4 Mar 2014, In : eLife. 2014, 3, e01630.

Research output: Contribution to journalArticle

Open Access
File
72 Citations (Scopus)
114 Downloads (Pure)
2011

A role for SUMOylation in snoRNP biogenesis revealed by quantitative proteomics

Westman, B. J. & Lamond, A. I., 1 Jan 2011, In : Nucleus. 2, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2012

Human box C/D snoRNA processing conservation across multiple cell types

Scott, M. S., Ono, M., Yamada, K., Endo, A., Barton, G. J. & Lamond, A. I., Apr 2012, In : Nucleic Acids Research. 40, 8, p. 3676-3688 13 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2011

The Nucleolus

Hutten, S., Westman, B. J., Boisvert, F. M., van Koningsbruggen, V. K. & Lamond, A. I., 14 Nov 2011, Genome Organization and Function in the Cell Nucleus. Weinheim: Wiley-VCH , p. 279-307 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Quantitative Proteomics and Dynamic Imaging of the Nucleolus Reveal Distinct Responses to UV and Ionizing Radiation

Moore, H. M., Bai, B., Boisvert, F-M., Latonen, L., Rantanen, V., Simpson, J. C., Pepperkok, R., Lamond, A. I. & Laiho, M., Oct 2011, In : Molecular & Cellular Proteomics. 10, 10, p. - 15 p., M111.009241.

Research output: Contribution to journalArticle

78 Citations (Scopus)
2013

FMN2 is a novel regulator of the cyclin-dependent kinase inhibitor p21

Yamada, K., Ono, M., Bensaddek, D., Lamond, A. I. & Rocha, S., 1 Aug 2013, In : Cell cycle (Georgetown, Tex.). 12, 15, p. 2348-2354 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2017

Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS

Ly, T., Whigham, A., Clarke, R., Brenes-Murillo, A. J., Estes, B., Madhessian, D., Lundberg, E., Wadsworth, P. & Lamond, A. I., 20 Oct 2017, In : eLife. 6, p. 1-35 35 p., e27574.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
207 Downloads (Pure)
2016

Micro-proteomics with iterative data analysis: proteome analysis in C.elegans at the single worm level

Bensaddek, D., Narayan, V., Nicolas, A., Brenes Murillo, A., Gartner, A., Kenyon, C. & Lamond, A., 10 Feb 2016, In : Proteomics. 16, 3, p. 381-392

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
134 Downloads (Pure)
2018

Efficient Analysis of Mammalian Polysomes in cells and tissues using Ribo Mega-SEC

Yoshikawa, H., Larance, M., Harney, D. J., Sundaramoorthy, R., Ly, T., Owen-Hughes, T. & Lamond, A. I., 10 Aug 2018, In : eLife. 7, 7, p. 1-26 26 p., e36530.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
133 Downloads (Pure)
2011

Exo70, a subunit of the exocyst complex, interacts with SNEVhPrp19/hPso4 and is involved in pre-mRNA splicing

Dellago, H., Löscher, M., Ajuh, P., Ryder, U., Kaisermayer, C., Grillari-Voglauer, R., Fortschegger, K., Gross, S., Gstraunthaler, A., Borth, N., Eisenhaber, F., Lamond, A. I. & Grillari, J., 15 Aug 2011, In : Biochemical Journal. 438, p. 81-91 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2018

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis

Liakath-Ali, K., Mills, E. W., Sequeira, I., Lichtenberger, B. M., Pisco, A. O., Sipilä, K. H., Mishra, A., Yoshikawa, H., Wu, C. C-C., Ly, T., Lamond, A. I., Adham, I. M., Green, R. & Watt, F. M., 11 Apr 2018, In : Nature. 556, p. 376-380 5 p.

Research output: Contribution to journalLetter

Open Access
File
16 Citations (Scopus)
258 Downloads (Pure)
2011

Quantitative Proteomic Analysis of Chromatin Reveals that Ctf18 Acts in the DNA Replication Checkpoint

Kubota, T., Hiraga, S., Yamada, K., Lamond, A. I. & Donaldson, A. D., Jul 2011, In : Molecular & Cellular Proteomics. 10, 7, p. - 14 p., M110.005561. .

Research output: Contribution to journalArticle

43 Citations (Scopus)
2017

A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis

Mishra, A., Oulès, B., Pisco, A. O., Ly, T., Liakath-Ali, K., Walko, G., Viswanathan, P., Tihy, M., Nijjhar, J., Dunn, S-J., Lamond, A. I. & Watt, F. M., 18 Oct 2017, In : eLife. 6, p. 1-20 20 p., e27356.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
223 Downloads (Pure)
2014

FMDV replicons encoding green fluorescent protein are replication competent

Tulloch, F., Pathania, U., Luke, G. A., Nicholson, J., Stonehouse, N. J., Rowlands, D. J., Jackson, T., Tuthill, T., Haas, J., Lamond, A. I. & Ryan, M. D., 1 Dec 2014, In : Journal of Virological Methods. 209, p. 35-40 6 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
125 Downloads (Pure)
2018
File
3 Citations (Scopus)
130 Downloads (Pure)

Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCFSlmb degron

Gray, K. M., Kaifer, K. A., Baillat, D., Wen, Y., Bonacci, T. R., Ebert, A. D., Raimer, A. C., Spring, A. M., Have, S. T., Glascock, J. J., Gupta, K., Van Duyne, G. D., Emanuele, M. J., Lamond, A. I., Wagner, E. J., Lorson, C. L. & Matera, A. G., 15 Jan 2018, In : Molecular Biology of the Cell. 29, 2, p. 96-110 15 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
108 Downloads (Pure)
2020

Population-scale proteome variation in human induced pluripotent stem cells

Mirauta, B. A., Seaton, D. D., Bensaddek, D., Brenes Murillo, A., Bonder, M. J., Kilpinen, H., Stegle, O. & Lamond, A. I., 10 Aug 2020, In : eLife. 9

Research output: Contribution to journalArticle

Open Access

Quantitative profiling of the human substantia nigra proteome from laser-capture microdissected FFPE tissue

Griesser, E., Wyatt, H., Ten Have, S., Stierstorfer, B., Lenter, M. & Lamond, A. I., 1 May 2020, In : Molecular & Cellular Proteomics. 19, 5, p. 839-851 13 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
28 Downloads (Pure)
2013

RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans

Akay, A., Craig, A., Lehrbach, N., Larance, M., Pourkarimi, E., Wright, J. E., Lamond, A., Miska, E. & Gartner, A., Nov 2013, In : Open Biology. 3, 130151.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2016

Enhanced snoMEN Vectors Facilitate Establishment of GFP–HIF-1α Protein Replacement Human Cell Lines

Ono, M., Ono, K., Bensaddek, D., Afzal, V., Biddlestone, J., Ortmann, B., Mudie, S., Boivin, V., S. Scott, M., Rocha, S. & Lamond, A. I., 29 Apr 2016, In : PLoS ONE. 11, 4, 28 p., e0154759.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
179 Downloads (Pure)
2019

Signal enhanced proteomics: a biological perspective on dissecting the functional organisation of cell proteomes

Bensaddek, D., Nicolas, A. & Lamond, A. I., Feb 2019, In : Current Opinion in Chemical Biology. 48, p. 114-122 9 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2016

Global membrane protein interactome analysis using in vivo crosslinking and MS-based protein correlation profiling

Larance, M., Kirkwood, K. J., Tinti, M., Brenes Murillo, A., Ferguson, M. & Lamond, A., 1 Jul 2016, In : Molecular & Cellular Proteomics. 15, 7, p. 2476-2490 15 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
125 Downloads (Pure)

The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway

Bailly, A., Perrin, A., Bou Malhab, L. J., Pion, E., Larance, M., Nagala, M., Smith, P., O'Donohue, M-F., Gleizes, P-E., Zomerdijk, J., Lamond, A. I. & Xirodimas, D. P., 28 Jan 2016, In : Oncogene. 35, 4, p. 415-426 12 p.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
310 Downloads (Pure)
2019
Open Access
File
13 Citations (Scopus)
16 Downloads (Pure)
2012

Perturbation of Chromatin Structure Globally Affects Localization and Recruitment of Splicing Factors

Schor, I. E., Llères, D., Risso, G. J., Pawellek, A., Ule, J., Lamond, A. I. & Kornblihtt, A. R., 12 Nov 2012, In : PLoS ONE. 7, 11, 16 p., e48084.

Research output: Contribution to journalArticle

Open Access
File
39 Citations (Scopus)
130 Downloads (Pure)