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Author

  • Henry McSorley
2018

Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis

Robb, C. T., McSorley, H. J., Lee, J., Aoki, T., Yu, C., Crittenden, S., Astier, A., Felton, J. M., Parkinson, N., Ayele, A., Breyer, R. M., Anderton, S. M., Narumiya, S., Rossi, A. G., Howie, S. E., Guttman-Yassky, E., Weller, R. B. & Yao, C., Jan 2018, In : Journal of Allergy and Clinical Immunology. 141, 1, p. 152-162 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014

Helminths and Immunological Tolerance

Johnston, C. J. C., McSorley, H. J., Anderton, S. M., Wigmore, S. J. & Maizels, R. M., 27 Jan 2014, In : Transplantation. 97, 2, p. 127-132 6 p.

Research output: Contribution to journalReview article

Open Access
File
22 Citations (Scopus)
32 Downloads (Pure)
2015

Cultivation of Heligmosomoides polygyrus: An immunomodulatory nematode parasite and its secreted products

Johnston, C. J. C., Robertson, E., Harcus, Y., Grainger, J. R., Coakley, G., Smyth, D. J., McSorley, H. J. & Maizels, R., 6 Apr 2015, In : Journal of Visualized Experiments. 98, p. 1-10 10 p., e52412.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
43 Downloads (Pure)
2014

Helminths in the hygiene hypothesis: Sooner or later?

Maizels, R. M., Mcsorley, H. J. & Smyth, D. J., Jul 2014, In : Clinical and Experimental Immunology. 177, 1, p. 38-46 9 p.

Research output: Contribution to journalArticle

Open Access
File
58 Citations (Scopus)
36 Downloads (Pure)
2016

Stage-specific proteomes from onchocerca ochengi, sister species of the human river blindness parasite, uncover adaptations to a nodular lifestyle

Armstrong, S. D., Xia, D., Bah, G. S., Krishna, R., Ngangyung, H. F., La Course, E. J., McSorley, H. J., Kengne-Ouafo, J. A., Chounna-Ndongmo, P. W., Wanji, S., Enyong, P. A., Taylor, D. W., Blaxter, M. L., Wastling, J. M., Tanya, V. N. & Makepeace, B. L., Aug 2016, In : Molecular and Cellular Proteomics. 15, 8, p. 2554-2575 22 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
22 Downloads (Pure)

Regulation of the host immune system by helminth parasites

Maizels, R. M. & McSorley, H. J., Sep 2016, In : Journal of Allergy and Clinical Immunology. 138, 3, p. 666-675 10 p.

Research output: Contribution to journalArticle

Open Access
File
167 Citations (Scopus)
33 Downloads (Pure)
2018

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus

Smyth, D. J., Harcus, Y., White, M. P. J., Gregory, W. F., Nahler, J., Stephens, I., Toke-Bjolgerud, E., Hewitson, J. P., Ivens, A., McSorley, H. J. & Maizels, R. M., Apr 2018, In : International Journal for Parasitology. 48, 5, p. 379-385 7 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
31 Downloads (Pure)

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

Maizels, R. M., Smits, H. H. & McSorley, H. J., 20 Nov 2018, In : Immunity. 49, 5, p. 801-818 18 p.

Research output: Contribution to journalReview article

Open Access
File
49 Citations (Scopus)
43 Downloads (Pure)
2014

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

Buck, A. H., Coakley, G., Simbari, F., McSorley, H. J., Quintana, J. F., Le Bihan, T., Kumar, S., Abreu-Goodger, C., Lear, M., Harcus, Y., Ceroni, A., Babayan, S. A., Blaxter, M., Ivens, A. & Maizels, R. M., 25 Nov 2014, In : Nature Communications. 5, p. 1-11 11 p., 5488.

Research output: Contribution to journalArticle

Open Access
File
329 Citations (Scopus)
37 Downloads (Pure)
2017

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

Johnston, C. J. C., Smyth, D. J., Kodali, R. B., White, M. P. J., Harcus, Y., Filbey, K. J., Hewitson, J. P., Hinck, C. S., Ivens, A., Kemter, A. M., Kildemoes, A. O., Le Bihan, T., Soares, D. C., Anderton, S. M., Brenn, T., Wigmore, S. J., Woodcock, H. V., Chambers, R. C., Hinck, A. P., McSorley, H. J. & 1 others, Maizels, R. M., 23 Nov 2017, In : Nature Communications. 8, p. 1-13 13 p., 1741.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
38 Downloads (Pure)
2015

Erratum: Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity(Nature Communications (2014) 5(5488) 10.1038/ncomms6488)

Buck, A. H., Coakley, G., Simbari, F., McSorley, H. J., Quintana, J. F., Le Bihan, T., Kumar, S., Abreu-Goodger, C., Lear, M., Harcus, Y., Ceroni, A., Babayan, S. A., Blaxter, M., Ivens, A. & Maizels, R. M., 22 Oct 2015, In : Nature Communications. 6, 1 p., 8772.

Research output: Contribution to journalComment/debate

Open Access
File
5 Citations (Scopus)
20 Downloads (Pure)
2017

IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks

Serrels, B., McGivern, N., Canel, M., Byron, A., Johnson, S. C., McSorley, H. J., Quinn, N., Taggart, D., Von Kreigsheim, A., Anderton, S. M., Serrels, A. & Frame, M. C., 5 Dec 2017, In : Science Signaling. 10, 508, p. 1-13 13 p., eaan8355.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2020

Reply to comment from Carl Persson

McSorley, H. & Johansson, K., 17 Apr 2020, In : Pediatric Allergy and Immunology. 31, 3, p. 338-339 2 p.

Research output: Contribution to journalLetter

2016

Microbes and asthma: Opportunities for intervention

Smits, H. H., Hiemstra, P. S., Prazeres Da Costa, C., Ege, M., Edwards, M., Garn, H., Howarth, P. H., Jartti, T., De Jong, E. C., Maizels, R. M., Marsland, B. J., McSorley, H. J., Müller, A., Pfefferle, P. I., Savelkoul, H., Schwarze, J., Unger, W. W. J., Von Mutius, E., Yazdanbakhsh, M. & Taube, C., Mar 2016, In : Journal of Allergy and Clinical Immunology. 137, 3, p. 690-697 8 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)
2020

A Truncated Form of HpARI Stabilizes IL-33, Amplifying Responses to the Cytokine

Chauché, C., Vacca, F., Chia, S. L., Richards, J., Gregory, W. F., Ogunkanbi, A., Wear, M. A. & McSorley, H. J., 30 Jun 2020, In : Frontiers in Immunology. 11, 10 p., 1363.

Research output: Contribution to journalArticle

Open Access
File
13 Downloads (Pure)
2014

Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy

McSorley, H. J., Blair, N. F., Smith, K. A., McKenzie, A. N. J. & Maizels, R. M., Sep 2014, In : Mucosal Immunology. 7, 5, p. 1068-1078 11 p.

Research output: Contribution to journalArticle

Open Access
File
108 Citations (Scopus)
31 Downloads (Pure)
2018

Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion

Smith, K. A., Löser, S., Varyani, F., Harcus, Y., McSorley, H. J., McKenzie, A. N. J. & Maizels, R. M., 5 Oct 2018, In : eLife. 7, p. 1-18 18 p., e38269.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
33 Downloads (Pure)
2016

Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation

Jackson-Jones, L. H., Duncan, S. M., Magalhaes, M. S., Campbell, S. M., Maizels, R. M., McSorley, H. J., Allen, J. E. & Bénézech, C., 1 Sep 2016, In : Nature Communications. 7, p. 1-14 14 p., 12651.

Research output: Contribution to journalArticle

Open Access
File
38 Citations (Scopus)
35 Downloads (Pure)
2017

Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer

Pastille, E., Frede, A., McSorley, H. J., Gräb, J., Adamczyk, A., Kollenda, S., Hansen, W., Epple, M., Buer, J., Maizels, R. M., Klopfleisch, R. & Westendorf, A. M., 22 Sep 2017, In : PLoS Pathogens. 13, 9, p. 1-22 22 p., e1006649.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
49 Downloads (Pure)
2020

A helminth-derived suppressor of ST2 blocks allergic responses

Vacca, F., Chauché, C., Jamwal, A., Hinchy, E. C., Heieis, G., Webster, H., Ogunkanbi, A., Sekne, Z., Gregory, W. F., Wear, M. A., Perona-Wright, G., Higgins, M. K. ., Nys, J., Cohen, E. S. & McSorley, H. J., 18 May 2020, In : eLife. 9, p. 1-20 20 p., e54017.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
61 Downloads (Pure)
2015
16 Citations (Scopus)
2016

Novel O-linked methylated glycan antigens decorate secreted immunodominant glycoproteins from the intestinal nematode Heligmosomoides polygyrus

Hewitson, J. P., Nguyen, D. L., van Diepen, A., Smit, C. H., Koeleman, C. A., McSorley, H. J., Murray, J., Maizels, R. M. & Hokke, C. H., Mar 2016, In : International Journal for Parasitology. 46, 3, p. 157-170 14 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
31 Downloads (Pure)
2017

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33

Osbourn, M., Soares, D. C., Vacca, F., Cohen, E. S., Scott, I. C., Gregory, W. F., Smyth, D. J., Toivakka, M., Kemter, A. M., le Bihan, T., Wear, M., Hoving, D., Filbey, K. J., Hewitson, J. P., Henderson, H., Gonzàlez-Cìscar, A., Errington, C., Vermeren, S., Astier, A. L., Wallace, W. A. & 4 others, Schwarze, J., Ivens, A. C., Maizels, R. M. & McSorley, H. J., 17 Oct 2017, In : Immunity. 47, 4, p. 739-751.e5 19 p.

Research output: Contribution to journalArticle

Open Access
File
47 Citations (Scopus)
39 Downloads (Pure)
2016

IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha

Jackson-Jones, L. H., Rückerl, D., Svedberg, F., Duncan, S., Maizels, R. M., Sutherland, T. E., Jenkins, S. J., McSorley, H. J., Bénézech, C., MacDonald, A. S. & Allen, J. E., Oct 2016, In : European Journal of Immunology. 46, 10, p. 2311-2321 11 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
40 Downloads (Pure)
2017

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota

McFarlane, A. J., McSorley, H. J., Davidson, D. J., Fitch, P. M., Errington, C., Mackenzie, K. J., Gollwitzer, E. S., Johnston, C. J. C., MacDonald, A. S., Edwards, M. R., Harris, N. L., Marsland, B. J., Maizels, R. M. & Schwarze, J., Oct 2017, In : Journal of Allergy and Clinical Immunology. 140, 4, p. 1068-1078.e6 17 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity

Coakley, G., McCaskill, J. L., Borger, J. G., Simbari, F., Robertson, E., Millar, M., Harcus, Y., McSorley, H. J., Maizels, R. M. & Buck, A. H., 23 May 2017, In : Cell Reports. 19, 8, p. 1545-1557 13 p.

Research output: Contribution to journalArticle

Open Access
File
69 Citations (Scopus)
32 Downloads (Pure)

Differential lower airway dendritic cell patterns May reveal distinct endotypes of RSV bronchiolitis

Kerrin, A., Fitch, P., Errington, C., Kerr, D., Waxman, L., Riding, K., McCormack, J., Mehendele, F., McSorley, H., MacKenzie, K., Wronski, S., Braun, A., Levin, R., Theilen, U. & Schwarze, J., Jul 2017, In : Thorax. 72, 7, p. 620-627 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2018

Basal Instinct: Persistence of Barrier Dysfunction

Chauché, C. & McSorley, H. J., 16 Oct 2018, In : Immunity. 49, 4, p. 590-592 3 p.

Research output: Contribution to journalShort survey

1 Citation (Scopus)