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  • Colin Palmer
2019

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia

Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., Richards, A., Owen, M. J., O'Donovan, M. C., Walters, J., Wellcome Trust Case Control Consortium 2, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Donohoe, G., Gill, M., Corvin, A. & Morris, D. W., Apr 2019, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2014

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes

Ng, M. C. Y., Shriner, D., Chen, B. H., Li, J., Chen, W-M., Guo, X., Liu, J., Bielinski, S. J., Yanek, L. R., Nalls, M. A., Comeau, M. E., Rasmussen-Torvik, L. J., Jensen, R. A., Evans, D. S., Sun, Y. V., An, P., Patel, S. R., Lu, Y., Long, J., Armstrong, L. L. & 32 others, Wagenknecht, L., Yang, L., Snively, B. M., Palmer, N. D., Mudgal, P., Langefeld, C. D., Keene, K. L., Freedman, B. I., Mychaleckyj, J. C., Nayak, U., Raffel, L. J., Goodarzi, M. O., Chen, Y-D. I., Taylor, H. A., Correa, A., Sims, M., Couper, D., Pankow, J. S., Boerwinkle, E., Adeyemo, A., Doumatey, A., Chen, G., Mathias, R. A., Vaidya, D., Singleton, A. B., Zonderman, A. B., Igo, R. P., for the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium, FIND Consortium, eMERGE Consortium, DIAGRAM Consortium & MuTHER Consortium, 7 Aug 2014, In : PLoS Genetics. 10, 8, p. 1-14 14 p., e1004517.

Research output: Contribution to journalArticle

Open Access
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113 Citations (Scopus)
127 Downloads (Pure)
2015

Biological interpretation of genome-wide association studies using predicted gene functions

Pers, T. H., Karjalainen, J. M., Chan, Y., Westra, H-J., Wood, A. R., Yang, J., Lui, J. C., Vedantam, S., Gustafsson, S., Esko, T., Frayling, T., Speliotes, E. K., Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Boehnke, M., Raychaudhuri, S., Fehrmann, R. S. N., Hirschhorn, J. N. & Franke, L., 19 Jan 2015, In : Nature Communications. 6, p. 1-9 9 p., 5890.

Research output: Contribution to journalArticle

301 Citations (Scopus)
2016

A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

Bodea, C. A., Neale, B. M., Ripke, S., International IBD Genetics Consortium, Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In : American Journal of Human Genetics. 98, 5, p. 857-868 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

Warren, H. R., Evangelou, E., Cabrera, C. P., Gao, H., Ren, M., Mifsud, B., Ntalla, I., Surendran, P., Liu, C., Cook, J. P., Kraja, A. T., Drenos, F., Loh, M., Verweij, N., Marten, J., Karaman, I., Lepe, M. P. S., O'Reilly, P. F., Knight, J., Snieder, H. & 35 others, Kato, N., He, J., Tai, E. S., Said, M. A., Porteous, D., Alver, M., Poulter, N., Farrall, M., Gansevoort, R. T., Padmanabhan, S., Mägi, R., Stanton, A., Connell, J., Bakker, S. J. L., Metspalu, A., Shields, D. C., Thom, S., Brown, M., Sever, P., Esko, T., Hayward, C., van der Harst, P., Saleheen, D., Chowdhury, R., Chambers, J. C., Chasman, D. I., Chakravarti, A., The International Consortium of Blood Pressure (ICBP) 1000G Analyses, The CHD Exome+ Consortium, The ExomeBP Consortium, The T2D-GENES Consortium, The GoT2DGenes Consortium, The Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium, The International Genomics of Blood Pressure (iGEN-BP) Consortium & The UK Biobank CardioMetabolic Consortium BP working group, Jan 2017, In : Nature Genetics. 49, 3, p. 403-415 16 p.

Research output: Contribution to journalArticle

Open Access
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196 Citations (Scopus)
150 Downloads (Pure)
2019

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Mahajan, A., Hingorani, A. D., Patel, R. S., Hemingway, H., Franks, P. W., Bell, J. D., Banerjee, R. & Yaghootkar, H., Sep 2019, In : Journal of Hepatology. 71, 3, p. 594-602 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
77 Downloads (Pure)
2018

Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS)

Hébert, H. L., Shepherd, B., Milburn, K., Veluchamy, A., Meng, W., Carr, F., Donnelly, L. A., Tavendale, R., Leese, G., Colhoun, H. M., Dow, E., Morris, A. D., Doney, A. S., Lang, C. C., Pearson, E. R., Smith, B. H. & Palmer, C. N. A., 1 Apr 2018, In : International Journal of Epidemiology. 47, 2, p. 380-381j 12 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
219 Downloads (Pure)
2017

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

Wain, L. V., Vaez, A., Jansen, R., Joehanes, R., van der Most, P. J., Erzurumluoglu, A. M., O’Reilly, P. F., Cabrera, C. P., Warren, H. R., Rose, L. M., Verwoert, G. C., Hottenga, J. J., Strawbridge, R. J., Esko, T., Arking, D. E., Hwang, S-J., Guo, X., Kutalik, Z., Trompet, S., Shrine, N. R. G. & 223 others, Teumer, A., Ried, J. S., Bis, J. C., Smith, A. V., Amin, N., Nolte, I. M., Lyytikäinen, L-P., Mahajan, A., Wareham, N. J., Hofer, E., Joshi, P. K., Kristiansson, K., Traglia, M., Havulinna, A. S., Goel, A., Nalls, M. A., Sõber, S., Vuckovic, D., Luan, J., Del Greco M., F., Ayers, K. L., Marrugat, J., Ruggiero, D., Lopez, L. M., Niiranen, T., Enroth, S., Jackson, A. U., Nelson, C. P., Huffman, J. E., Zhang, W., Marten, J., Gandin, I., Harris, S. E., Zemunik, T., Lu, Y., Evangelou, E., Shah, N., De Borst, M. H., Mangino, M., Prins, B. P., Campbell, A., Li-Gao, R., Chauhan, G., Oldmeadow, C., Abecasis, G. R., Abedi, M., Barbieri, C. M., Barnes, M. R., Batini, C., Beilby, J. P., Blake, T., Boehnke, M., Bottinger, E. P., Braund, P. S., Brown, M. J., Brumat, M., Campbell, H., Chambers, J. C., Cocca, M., Collins, F. S., Connell, J., Cordell, H. J., Damman, J. J., Davies, G., de Geus, E. J. C., de Mutsert, R., Deelen, J., Demirkale, Y., Doney, A. S. F., Dörr, M., Farrall, M., Ferreira, T., Frånberg, M., Gao, H., Giedraitis, V., Gieger, C., Giulianini, F., Gow, A. J., Hamsten, A., Harris, T. B., Hofman, A., Holliday, E. G., Hui, J., Jarvelin, M-R., Johansson, Å., Johnson, A. D., Jousilahti, P. R., Jula, A., Kähönen, M., Kathiresan, S., Khaw, K-T., Kolcic, I., Koskinen, S., Langenberg, C., Larson, M., Launer, L. J., Lehne, B., Liewald, D. C. M., Lin, L-A., Lind, L., Mach, F., Mamasoula, C., Menni, C., Mifsud, B., Aulchenko, Y., Morgan, A., Morris, A. D., Morrison, A. C., Munson, P. J., Nandakumar, P., Nguyen, Q. T., Nutile, T., Oldehinkel, A. J., Oostra, B. A., Org, E., Padmanabhan, S., Palotie, A., Paré, G., Pattie, A., Penninx, B. W. J. H., Poulter, N. R., Pramstaller, P. P., Raitakari, O. T., Ren, M., Rice, K., Ridker, P. M., Riese, H., Ripatti, S., Robino, A., Rotter, J. I., Rudan, I., Saba, Y., Saint Pierre, A., Sala, C. F., Sarin, A-P., Schmidt, R., Scott, R. J., Seelen, M. A. J., Shields, D. C., Siscovick, D. S., Sorice, R., Stanton, A., Stott, D. J., Sundström, J., Swertz, M. A., Taylor, K. D., Thom, S., Tzoulaki, I., Tzourio, C., Uitterlinden, A. G., Völker, U., Vollenweider, P., Wild, S. H., Willemsen, G., Wright, A. F., Yao, J., Thériault, S., Conen, D., Attia, J. R., Sever, P., Debette, S., Mook-Kanamori, D. O., Zeggini, E., Spector, T. D., van der Harst, P., Palmer, C. N. A., Vergnaud, A-C., Loos, R. J. F., Polasek, O., Starr, J. M., Girotto, G., Hayward, C., Kooner, J. S., Lindgren, C. M., Vitart, V., Samani, N. J., Tuomilehto, J., Gyllensten, U. B., Knekt, P., Deary, I. J., Ciullo, M., Elosua, R., Keavney, B. D., Hicks, A. A., Scott, R. A., Gasparini, P., Laan, M., Liu, Y., Watkins, H., Hartman, C. A., Salomaa, V., Toniolo, D., Perola, M., Wilson, J. F., Schmidt, H., Zhao, J. H., Lehtimäki, T., van Duijn, C. M., Gudnason, V., Psaty, B. M., Peters, A., Rettig, R., James, A. L., Jukema, J. W., Strachan, D. P., Palmas, W., Metspalu, A., Ingelsson, E., Boomsma, D. I., Franco, O. H., Bochud, M., Newton-Cheh, C., Munroe, P. B., Elliott, P., Chasman, D. I., Chakravarti, A., Knight, J., Morris, A. P., Levy, D., Tobin, M. D., Snieder, H., Caulfield, M. J. & Ehret, G. B., 24 Jul 2017, In : Hypertension. 70, 3, p. e4-e19 16 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
2018

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference

Corbin, L. J., Tan, V. Y., Hughes, D. A., Wade, K., Paul, D. S., Tansey, K. E., Butcher, F., Dudbridge, F., Howson, J. M. M., Jallow, M. W., John, C., Kingston, N., Lindgren, C. M., O’Donavan, M., O'Rahilly, S., Owen, M. J., Palmer, C., Pearson, E., Scott, R. A., van Heel, D. & 11 others, Whittaker, J., Frayling, T., Tobin, M. D., Wain, L. V., Smith, G. D., Evans, D. M., Karpe, F., McCarthy, M. I., Danesh, J., Franks, P. W. & Timpson, N. J., 19 Feb 2018, In : Nature Communications. 9, 1, p. 1-11 11 p., 711.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
161 Downloads (Pure)
2017

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

CHD Exome+ Consortium, ExomeBP Consortium, GoT2D Genes Consortium, The UK Biobank CardioMetabolic Consortium BP working group, Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-Jensen, J., Brandslund, I., Farmaki, A-E. & 36 others, Fava, C., Ferreira, T., Herzig, K-H., Giri, A., Giulianini, F., Grove, M. L., Guo, X., Harris, S. E., Have, C. T., Havulinna, A. S., Zhang, H., Jørgensen, M. E., Käräjämäki, A. M., Kooperberg, C., Linneberg, A., Little, L., Liu, Y., Bonnycastle, L. L., Lu, Y., Mägi, R., Mahajan, A., Malerba, G., Marioni, R. E., Mei, H., Menni, C., Morrison, A. C., Padmanabhan, S., Palmas, W., Poveda, A., Rauramaa, R., Rayner, N. W., Connell, J. M., Morris, A. P., Palmer, C. N. A., The Understanding Society Scientific Group & CHARGE EXOME BP, 13 Oct 2017, In : Circulation: Cardiovascular Genetics. 10, 5, e001778.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
304 Downloads (Pure)
2018

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

Finnish Diabetic Nephropathy Study (FinnDiane), Surrogate Markers for Micro- and Macro-Vascular Hard Endpoints for Innovative Diabetes Tools (SUMMIT) Study Group, GENIE (GEnetics of Nephropathy an International Effort) Consortium, Warren 3 and Genetics of Kidneys in Diabetes (GoKinD) Study Group, Van Zuydam, N. R., Ahlqvist, E., Sandholm, N., Deshmukh, H., Rayner, N. W., Abdalla, M., Ladenvall, C., Ziemek, D., Fauman, E., Robertson, N. R., McKeigue, P. M., Valo, E., Forsblom, C., Harjutsalo, V., Perna, A., Rurali, E. & 65 others, Marcovecchio, M. L., Igo, R. P., Salem, R. M., Perico, N., Lajer, M., Käräjämäki, A., Imamura, M., Kubo, M., Takahashi, A., Sim, X., Liu, J., Van Dam, R. M., Jiang, G., Tam, C. H. T., Luk, A. O. Y., Lee, H. M., Lim, C. K. P., Szeto, C. C., So, W. Y., Chan, J. C. N., Ang, S. F., Dorajoo, R., Wang, L., Clara, T. S. H., McKnight, A. J., Duffy, S., Pezzolesi, M. G., Marre, M., Gyorgy, B., Hadjadj, S., Hiraki, L. T., Ahluwalia, T. S., Almgren, P., Schulz, C-A., Orho-Melander, M., Linneberg, A., Christensen, C., Witte, D. R., Grarup, N., Brandslund, I., Melander, O., Paterson, A. D., Trégouët, D-A., Maxwell, A. P., Lim, S. C., Ma, R. C. W., Tai, E. S., Maeda, S., Lyssenko, V., Tuomi, T., Krolewski, A., Rich, S. S., Hirschhorn, J. N., Florez, J. C., Dunger, D., Pedersen, O., Hansen, T., Rossing, P., Remuzzi, G., Brosnan, M. J., Palmer, C. N. A., Groop, P-H., Colhoun, H. M., Groop, L. C. & McCarthy, M. I., Jul 2018, In : Diabetes. 67, 7, p. 1414-1427 14 p.

Research output: Contribution to journalArticle

Open Access
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38 Citations (Scopus)
105 Downloads (Pure)
2017
Open Access
File
10 Citations (Scopus)
149 Downloads (Pure)

A genome-wide association study suggested that the mitogen-activated protein kinase 14 gene (MAPK14) is associated with diabetic foot ulcer

Meng, W., Veluchamy, A., Hebert, H., Campbell, A., Colhoun, H. M. & Palmer, C., Dec 2017, In : British Journal of Dermatology. 177, 6, p. 1664-1670 7 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
120 Downloads (Pure)

CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia

Siddiqui, M. K., Veluchamy, A., Maroteau, C., Tavendale, R., Carr, F., Pearson, E., Colhoun, H., Morris, A. D., George, J., Doney, A., Pirmohamed, M., Alfirevic, A., Wadelius, M., Maitland-van der Zee, A. H., Ridker, P. M., Chasman, D. I., Palmer, C. N. A. & PREDICTION-ADR Consortium, Aug 2017, In : Circulation: Cardiovascular Genetics. 10, 4, e001737 .

Research output: Contribution to journalArticle

3 Citations (Scopus)

Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

Tragante, V., Gho, J. M. I. H., Felix, J. F., Vasan, R. S., Smith, N. L., Voight, B. F., Palmer, C., van der Harst, P., Moore, J. H., Asselbergs, F. W. & CHARGE Heart Failure Working Group, 26 May 2017, In : BioData Mining. 10, p. 1-11 11 p., 18.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
145 Downloads (Pure)

Cohort Profile: Scottish Diabetes Research Network Type 1 Bioresource Study (SDRNT1BIO)

Akbar, T., McGurnaghan, S., Palmer, C. N. A., Livingstone, S. J., Petrie, J. R., Chalmers, J., Lindsay, R. S., McKnight, J. A., Pearson, D. W. M., Patrick, A. W., Walker, J., Looker, H. C. & Colhoun, H. M., Jun 2017, In : International Journal of Epidemiology. 46, 3, p. 796-796i 10 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
161 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
157 Downloads (Pure)
2019

Meta-analysis of inhaled corticosteroids response in children with asthma

Hernandez-Pacheco, N., Vijverberg, S. J., Gorenjak, M., Flores, C., Francis, B., Farzan, N., Corrales, A., Karimi, L., Maroteau, C., Schieck, M., Repnik, K., Perez-Mendez, L., Soares, P., Berce, V., Tavendale, R., Sardon, O., Corcuera, P., Korta, J., Mukhopadhyay, S., Pirmohamed, M. & 8 others, Mc Verhamme, K., Kabesch, M., Hawcutt, D. B., Turner, S., Palmer, C. N., Potocnik, U., Maitland-Van Der Zee, A. H. & Pino-Yanes, M., 28 Sep 2019, In : European Respiratory Journal. 54, 63, PA5434.

Research output: Contribution to journalMeeting abstract

2020

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

Mahmoodi, B. K., Tragante, V., Kleber, M. E., Holmes, M. V., Schmidt, A. F., McCubrey, R. O., Howe, L. J., Direk, K., Allayee, H., Baranova, E. V., Braund, P. S., Delgado, G. E., Eriksson, N., Gijsberts, C. M., Gong, Y., Hartiala, J., Heydarpour, M., Pasterkamp, G., Kotti, S., Kuukasjärvi, P. & 64 others, Lenzini, P. A., Levin, D., Lyytikäinen, L-P., Muehlschlegel, J. D., Nelson, C. P., Nikus, K., Pilbrow, A. P., Tang, W. H. W., van der Laan, S. W., van Setten, J., Vilmundarson, R. O., Deanfield, J., Deloukas, P., Dudbridge, F., James, S., Mordi, I. R., Teren, A., Bergmeijer, T. O., Body, S. C., Bots, M., Burkhardt, R., Cooper-DeHoff, R. M., Cresci, S., Danchin, N., Doughty, R. N., Grobbee, D. E., Hagström, E., Hazen, S. L., Held, C., Hoefer, I. E., Hovingh, G. K., Johnson, J. A., Kaczor, M. P., Kähönen, M., Klungel, O. H., Laurikka, J. O., Lehtimäki, T., Maitland-van der Zee, A. H., McPherson, R., Palmer, C. N., Kraaijeveld, A. O., Pepine, C. J., Sanak, M., Sattar, N., Scholz, M., Simon, T., Spertus, J. A., Stewart, A. F. R., Szczeklik, W., Thiery, J., Visseren, F. L. J., Waltenberger, J., Richards, A. M., Lang, C. C., Cameron, V. A., Åkerblom, A., Pare, G., März, W., Samani, N. J., Hingorani, A. D., Ten Berg, J. M., Wallentin, L., Asselbergs, F. W. & Patel, R., 11 Aug 2020, In : Circulation. 142, 6, p. 546-555 10 p.

Research output: Contribution to journalArticle

2018

DOLORisk: Study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain [version 2; referees: 2 approved]

Pascal, M. M. V., Themistocleous, A. C., Baron, R., Binder, A., Bouhassira, D., Crombez, G., Finnerup, N. B., Gierthmühlen, J., Granovsky, Y., Groop, L., Hebert, H. L., Jensen, T. S., Johnsen, K., McCarthy, M. I., Meng, W., Palmer, C. N. A., Rice, A. S. C., Serra, J., Solà, R., Yarnitsky, D. & 3 others, Smith, B. H., Attal, N. & Bennett, D. L. H., 29 May 2018, In : Wellcome Open Research. 3, p. 1-23 23 p., 63.

Research output: Contribution to journalArticle

File
5 Citations (Scopus)
59 Downloads (Pure)
2020
Open Access
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2016

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

Postmus, I., Warren, H. R., Trompet, S., Arsenault, B. J., Avery, C. L., Bis, J. C., Chasman, D. I., de Keyser, C. E., Deshmukh, H. A., Evans, D. S., Feng, Q., Li, X., Smit, R. A. J., Smith, A. V., Sun, F., Taylor, K. D., Arnold, A. M., Barnes, M. R., Barratt, B. J., Betteridge, J. & 68 others, Boekholdt, S. M., Boerwinkle, E., Buckley, B. M., Chen, Y-D. I., de Craen, A. J. M., Cummings, S. R., Denny, J. C., Dubé, M. P., Durrington, P. N., Eiriksdottir, G., Ford, I., Guo, X., Harris, T. B., Heckbert, S. R., Hofman, A., Hovingh, G. K., Kastelein, J. J. P., Launer, L. J., Liu, C-T., Liu, Y., Lumley, T., McKeigue, P. M., Munroe, P. B., Neil, A., Nickerson, D. A., Nyberg, F., O'Brien, E., O'Donnell, C. J., Post, W., Poulter, N., Vasan, R. S., Rice, K., Rich, S. S., Rivadeneira, F., Sattar, N., Sever, P., Shaw-Hawkins, S., Shields, D. C., Slagboom, P. E., Smith, N. L., Smith, J. D., Sotoodehnia, N., Stanton, A., Stott, D. J., Stricker, B. H., Stürmer, T., Uitterlinden, A. G., Wei, W-Q., Westendorp, R. G. J., Whitsel, E. A., Wiggins, K. L., Wilke, R. A., Ballantyne, C. M., Colhoun, H. M., Cupples, L. A., Franco, O. H., Gudnason, V., Hitman, G., Palmer, C. N. A., Psaty, B. M., Ridker, P. M., Stafford, J. M., Stein, C. M., Tardif, J-C., Caulfield, M. J., Jukema, J. W., Rotter, J. I. & Krauss, R. M., Dec 2016, In : Journal of Medical Genetics. 53, 12, p. 835-845 11 p.

Research output: Contribution to journalArticle

Open Access
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19 Citations (Scopus)
143 Downloads (Pure)
2017

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

Webb, T. R., Erdmann, J., Stirrups, K. E., Stitziel, N. O., Masca, N. G. D., Jansen, H., Kanoni, S., Nelson, C. P., Ferrario, P. G., König, I. R., Eicher, J. D., Johnson, A. D., Hamby, S. E., Betsholtz, C., Ruusalepp, A., Franzén, O., Schadt, E. E., Björkegren, J. L. M., Weeke, P. E., Auer, P. L. & 31 others, Schick, U. M., Lu, Y., Zhang, H., Dube, M-P., Goel, A., Farrall, M., Peloso, G. M., Won, H-H., Do, R., van Iperen, E., Kruppa, J., Mahajan, A., Scott, R. A., Willenborg, C., Braund, P. S., van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Merlini, P. A., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C., El-Mokhtari, N. E., Franke, A., Heilmann, S., Hengstenberg, C., Morris, A. D., Palmer, C. N. A. & Wellcome Trust Case Control Consortium, MORGAM Investigators, Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, 21 Feb 2017, In : Journal of the American College of Cardiology. 69, 7, p. 823-836 14 p.

Research output: Contribution to journalArticle

Open Access
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94 Citations (Scopus)
212 Downloads (Pure)
2016

A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract

Chang, C., Zhang, K., Veluchamy, A., Hébert, H. L., Looker, H. C., Colhoun, H. M., Palmer, C. N. A. & Meng, W., 1 Apr 2016, In : Investigative Ophthalmology & Visual Science. 57, 4, p. 2246-50 5 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
149 Downloads (Pure)

Methotrexate in psoriasis under real-world conditions: long-term efficacy and tolerability

West, J., Ogston, S., Palmer, C., Fleming, C., Dawe, R., Kumar, V., Waterston, S. & Foerster, J., Jun 2016, In : British Journal of Dermatology. 174, 6, p. 1407-1410 4 p., 14452.

Research output: Contribution to journalLetter

9 Citations (Scopus)
2018

Response to "Influence of Diabetes on Antiplatelet Drug Efficacy"

Tornio, A., Palmer, C. N. A. & Doney, A. S. F., 1 Apr 2018, In : Clinical Pharmacology & Therapeutics. 103, 4, p. 573 1 p.

Research output: Contribution to journalLetter

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Variants in genes coding for glutathione S-transferases and asthma outcomes in children

Pharmacogenomics in Childhood Asthma Consortium, Turner, S., Francis, B., Wani, N., Vijverberg, S., Pino-Yanes, M., Mukhopadhyay, S., Tavendale, R., Palmer, C., Burchard, E. G., Merid, S. K., Melén, E. & Maitland-van der Zee, A. H., Jun 2018, In : Pharmacogenomics. 19, 8, p. 707-713 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Nikpay, M., Goel, A., Won, H-H., Hall, L. M., Willenborg, C., Kanoni, S., Saleheen, D., Kyriakou, T., Nelson, C. P., Hopewell, J. C., Webb, T. R., Zeng, L., Dehghan, A., Elver, M., Armasu, S. M., Auro, K., Bjonnes, A., Chasman, D. I., Chen, S., Ford, I. & 31 others, Franceschini, N., Gieger, C., Grace, C., Gustafsson, S., Huang, J., Hwang, S-J., Kim, Y. K., Kleber, M. E., Lau, K. W., Lu, X., Lu, Y., Lyytikäinen, L-P., Mihailov, E., Morrison, A. C., Pervjakova, N., Qu, L., Rose, L. M., Salfati, E., Saxena, R., Scholz, M., Smith, A. V., Tikkanen, E., Uitterlinden, A., Yang, X., Zhang, W., Zhao, W., de Andrade, M., de Vries, P. S., van Zuydam, N. R., Palmer, C. N. & for the CARDIoGRAMplusC4D Consortium, Oct 2015, In : Nature Genetics. 47, 10, p. 1121-1130 10 p.

Research output: Contribution to journalArticle

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713 Citations (Scopus)
1138 Downloads (Pure)
2016

Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: A meta-analysis stratified by treatment

Turner, S., Francis, B., Vijverberg, S., Pino-Yanes, M., Maitland-van der Zee, A. H., Basu, K., Bignell, L., Mukhopadhyay, S., Tavendale, R., Palmer, C., Hawcutt, D., Pirmohamed, M., Burchard, E. G. & Lipworth, B., Jul 2016, In : Journal of Allergy and Clinical Immunology. 138, 1, p. 107-113 7 p.

Research output: Contribution to journalArticle

Open Access
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38 Citations (Scopus)
167 Downloads (Pure)
2015

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Gaulton, K. J., Ferreira, T., Lee, Y., Raimondo, A., Mägi, R., Reschen, M. E., Mahajan, A., Locke, A., William Rayner, N., Robertson, N., Scott, R. A., Prokopenko, I., Scott, L. J., Green, T., Sparso, T., Thuillier, D., Yengo, L., Grallert, H., Wahl, S., Frånberg, M. & 29 others, Strawbridge, R. J., Kestler, H., Chheda, H., Eisele, L., Gustafsson, S., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Karssen, L. C., van Leeuwen, E. M., Willems, S. M., Li, M., Chen, H., Fuchsberger, C., Kwan, P., Ma, C., Linderman, M., Lu, Y., Thomsen, S. K., Rundle, J. K., Beer, N. L., van de Bunt, M., Chalisey, A., Kang, H. M., Voight, B. F., Doney, A. S. F., Morris, A. D., Palmer, C. N. A. & DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Dec 2015, In : Nature Genetics. 47, 12, p. 1415-1425 11 p.

Research output: Contribution to journalArticle

199 Citations (Scopus)
2014

Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J., 1 Jan 2014, In : Clinical Science. 126, 1, p. 75-83 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The correlation between reading and mathematics ability at age twelve has a substantial genetic component

Davis, O. S. P., Band, G., Pirinen, M., Haworth, C. M. A., Meaburn, E. L., Kovas, Y., Harlaar, N., Docherty, S. J., Hanscombe, K. B., Trzaskowski, M., Curtis, C. J. C., Strange, A., Freeman, C., Bellenguez, C., Su, Z., Pearson, R., Vukcevic, D., Langford, C., Deloukas, P., Hunt, S. & 31 others, Gray, E., Dronov, S., Potter, S. C., Tashakkori-Ghanbaria, A., Edkins, S., Bumpstead, S. J., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J. A. Z., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Barroso, I., Peltonen, L., Dale, P. S., Petrill, S. A., Schalkwyk, L. S., Craig, I. W., Lewis, C. M., Price, T. S., Donnelly, P. & Wellcome Trust Case Control Consortium, 8 Jul 2014, In : Nature Communications. 5, 6 p., 4204.

Research output: Contribution to journalArticle

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46 Citations (Scopus)
128 Downloads (Pure)

Pharmacogenetic analysis of GLCCI1 in three north European pediatric asthma populations with a reported use of inhaled corticosteroids

Vijverberg, S. J. H., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., Postma, D. S., Koppelman, G. H., Turner, S. W., Mukhopadhyay, S., Palmer, C. N. A. & Maitland-Van Der Zee, A. H., Apr 2014, In : Pharmacogenomics. 15, 6, p. 799-806 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Phenotype standardization for statin-induced myotoxicity

Alfirevic, A., Neely, D., Armitage, J., Chinoy, H., Cooper, R. G., Laaksonen, R., Carr, D. F., Bloch, K. M., Fahy, J., Hanson, A., Yue, Q. Y., Wadelius, M., Maitland-van Der Zee, A. H., Voora, D., Psaty, B. M., Palmer, C. N. A. & Pirmohamed, M., Oct 2014, In : Clinical Pharmacology & Therapeutics. 96, 4, p. 470-476 7 p.

Research output: Contribution to journalArticle

Open Access
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101 Citations (Scopus)
172 Downloads (Pure)
2015

ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults

Vijverberg, S. J. H., Koster, E. S., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., Postma, D. S., Koppelman, G. H., Turner, S. W., Mukhopadhyay, S., Tse, S. M., Tantisira, K. G., Hawcutt, D. B., Francis, B., Pirmohamed, M., Pino-Yanes, M., Eng, C., Burchard, E. G., Palmer, C. N. A. & Maitland-van der Zee, A. H., Jun 2015, In : Clinical and Experimental Allergy. 45, 6, p. 1051-1059 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease

Persson, J., Strawbridge, R. J., McLeod, O., Gertow, K., Silveira, A., Baldassarre, D., Van Zuydam, N., Shah, S., Fava, C., Gustafsson, S., Veglia, F., Sennblad, B., Larsson, M., Sabater-Lleal, M., Leander, K., Gigante, B., Tabak, A., Kivimaki, M., Kauhanen, J., Rauramaa, R. & 19 others, Smit, A. J., Mannarino, E., Giral, P., Humphries, S. E., Tremoli, E., de Faire, U., Lind, L., Ingelsson, E., Hedblad, B., Melander, O., Kumari, M., Hingorani, A., Morris, A. D., Palmer, C. N. A., Lundman, P., Öhrvik, J., Söderberg, S., Hamsten, A. & IMPROVE Study Group, 14 Aug 2015, In : Journal of the American Heart Association. 4, 8, e001853.

Research output: Contribution to journalArticle

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23 Citations (Scopus)
128 Downloads (Pure)
2016

Common Creatine Kinase gene mutation results in falsely reassuring CK levels in muscle disorders

Wallace, B., Siddiqui, M., Palmer, C. N. A. & George, J., 1 Jun 2016, In : QJM : an International Journal of Medicine. 109, 6, p. 413-414 3 p.

Research output: Contribution to journalArticle

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3 Citations (Scopus)
141 Downloads (Pure)
2013

Common Polymorphisms in the CYP11B1 and CYP11B2 Genes: Evidence for a Digenic Influence on Hypertension

Alvarez-Madrazo, S., MacKenzie, S. M., Davies, E., Fraser, R., Lee, W-K., Brown, M., Caulfield, M. J., Dominiczak, A. F., Farrall, M., Lathrop, M., Hedner, T., Melander, O., Munroe, P. B., Samani, N., Stewart, P. M., Wahlstrand, B., Webster, J., Palmer, C. N. A., Padmanabhan, S. & Connell, J. M., 2013, In : Hypertension. 61, 1, p. 232-239 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Glycaemic control and the development of heart failure

Parry, H., Donnelly, L., Van Zuydam, N., Morris, A., Elder, D. H., Doney, A. S. F., Palmer, C. N. A. & Lang, C. C., 2013, In : Journal of the American College of Cardiology. 61, 10 Supplement, p. E566 1 p.

Research output: Contribution to journalMeeting abstract

2011

Comparison of montelukast versus salmeterol in children with asthma carrying-at-risk beta(2)adrenergic receptor polymorphism: a genotype-stratified randomised controlled trial

Basu, K., Donald, H. P., Lipworth, B. J., Tavendale, R., MacGregor, D. F., Ogston, S. A., Palmer, C. N. A. & Mukhopadhyay, S., 2011, In : Journal of Allergy and Clinical Immunology. 127, 2 Supplement, p. AB212 1 p.

Research output: Contribution to journalBook/Film/Article review

2013

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Ripke, S., O'Dushlaine, C., Chambert, K., Moran, J. L., Kähler, A. K., Akterin, S., Bergen, S. E., Collins, A. L., Crowley, J. J., Fromer, M., Kim, Y., Lee, S. H., Magnusson, P. K. E., Sanchez, N., Stahl, E. A., Williams, S., Wray, N. R., Xia, K., Bettella, F., Borglum, A. D. & 31 others, Bulik-Sullivan, B. K., Cormican, P., Craddock, N., de Leeuw, C., Durmishi, N., Gill, M., Golimbet, V., Hamshere, M. L., Holmans, P., Hougaard, D. M., Kendler, K. S., Lin, K., Morris, D. W., Mors, O., Mortensen, P. B., Neale, B. M., O'Neill, F. A., Owen, M. J., Milovancevic, M. P., Posthuma, D., Powell, J., Richards, A. L., Riley, B. P., Ruderfer, D., Rujescu, D., Sigurdsson, E., Silagadze, T., Smit, A. B., Stefansson, H., Palmer, C. N. A. & Multicenter Genetic Studies of Schizophrenia Consortium, 2013, In : Nature Genetics. 45, 10, p. 1150-1159 10 p.

Research output: Contribution to journalArticle

924 Citations (Scopus)
2015

Protein biomarkers for the prediction of cardiovascular disease in type 2 diabetes

Looker, H. C., Colombo, M., Agakov, F., Zeller, T., Groop, L., Thorand, B., Palmer, C. N., Hamsten, A., de Faire, U., Nogoceke, E., Livingstone, S. J., Salomaa, V., Leander, K., Barbarini, N., Bellazzi, R., van Zuydam, N., McKeigue, P. M., Colhoun, H. M. & on behalf of the SUMMIT Investigators, Jun 2015, In : Diabetologia. 58, 6, p. 1363-1371 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2020

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Regeneron Genetics Center, Shah, S., Henry, A., Roselli, C., Lin, H., Sveinbjörnsson, G., Fatemifar, G., Hedman, Å. K., Wilk, J. B., Morley, M. P., Chaffin, M. D., Helgadottir, A., Verweij, N., Dehghan, A., Almgren, P., Andersson, C., Aragam, K. G., Ärnlöv, J., Backman, J. D., Biggs, M. L. & 32 others, Bloom, H. L., Brandimarto, J., Brown, M. R., Buckbinder, L., Carey, D. J., Chasman, D. I., Chen, X., Chen, X., Chung, J., Chutkow, W., Cook, J. P., Delgado, G. E., Denaxas, S., Doney, A. S., Dörr, M., Dudley, S. C., Dunn, M. E., Engström, G., Esko, T., Felix, S. B., Finan, C., Ford, I., Mordi, I. R., Morris, A. D., Morris, A. P., Palmer, C. N. A., Parry, H. M., Smith, N. L., Veluchamy, A., McMurray, J. J. V., Lang, C. C. & Lumbers, R. T., 9 Jan 2020, In : Nature Communications. 11, 12 p., 163.

Research output: Contribution to journalArticle

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17 Citations (Scopus)
88 Downloads (Pure)
2019

Effects of the coronary artery disease associated LPA and 9p21 loci on risk of aortic valve stenosis

Trenkwalder, T., Nelson, C. P., Musameh, M. D., Mordi, I. R., Kessler, T., Pellegrini, C., Debiec, R., Rheude, T., Lazovic, V., Zeng, L., Martinsson, A., Gustav Smith, J., Gådin, J. R., Franco-Cereceda, A., Eriksson, P., Nielsen, J. B., Graham, S. E., Willer, C. J., Hveem, K., Kastrati, A. & 9 others, Braund, P. S., Palmer, C. N. A., Aracil, A., Husser, O., Koenig, W., Schunkert, H., Lang, C. C., Hengstenberg, C. & Samani, N. J., 1 Feb 2019, In : International Journal of Cardiology. 276, p. 212-217 6 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
121 Downloads (Pure)
2020
Open Access
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10 Downloads (Pure)
2016

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

CHARGE-EchoGen Consortium, CHARGE-HF Consortium, Wellcome Trust Case Control Consortium, Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A-K., Pihur, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O., Kaakinen, M. & 35 others, Bouatia-Naji, N., Kristiansson, K., Shah, S., Kleber, M. E., Guo, X., Lyytikäinen, L-P., Fava, C., Eriksson, N., Nolte, I. M., Magnusson, P. K., Salfati, E. L., Rallidis, L. S., Theusch, E., Smith, A. J. P., Folkersen, L., Witkowska, K., Pers, T. H., Joehanes, R., Kim, S. K., Lataniotis, L., Jansen, R., Johnson, A. D., Warren, H., Kim, Y. J., Zhao, W., Wu, Y., Tayo, B. O., Bochud, M., Absher, D., Connell, J. M., Doney, A. S. F., Morris, A. D., Palmer, C. N. A., Newton-Cheh, C. & Munroe, P. B., Oct 2016, In : Nature Genetics. 48, p. 1171-1184 16 p.

Research output: Contribution to journalArticle

179 Citations (Scopus)
2020

Author Correction: Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank

Meng, W., Adams, M. J., Palmer, C. N. A., 23andMe Research Team, Shi, J., Auton, A., Ryan, K. A., Jordan, J. M., Mitchell, B. D., Jackson, R. D., Yau, M. S., McIntosh, A. M. & Smith, B. H., 26 Mar 2020, In : Communications Biology. 3, 1, 1 p., 149.

Research output: Contribution to journalArticle

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2018

DOLORisk: study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain

Pascal, M. M. V., Themistocleous, A. C., Baron, R., Binder, A., Bouhassira, D., Crombez, G., Finnerup, N. B., Gierthmühlen, J., Granovsky, Y., Groop, L., Hebert, H. L., Jensen, T. S., Johnsen, K., McCarthy, M. I., Meng, W., Palmer, C. N. A., Rice, A. S. C., Serra, J., Solà, R., Yarnitsky, D. & 3 others, Smith, B. H., Attal, N. & Bennett, D. L. H., 29 May 2018, In : Wellcome Open Research. 3, p. 1-16 16 p., 63.

Research output: Contribution to journalArticle

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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., Karaman, I., Ng, F. L., Evangelou, M., Witkowska, K., Tzanis, E., Hellwege, J. N., Giri, A., Velez Edwards, D. R., Sun, Y. V., Cho, K., Gaziano, J. M. & 31 others, Wilson, P. W. F., Tsao, P. S., Kovesdy, C. P., Esko, T., Mägi, R., Milani, L., Almgren, P., Boutin, T., Debette, S., Ding, J., Giulianini, F., Holliday, E. G., Jackson, A. U., Li-Gao, R., Lin, W-Y., Luan, J., Mangino, M., Oldmeadow, C., Prins, B. P., Qian, Y., Sargurupremraj, M., Shah, N., Surendran, P., Thériault, S., Verweij, N., Willems, S. M., Connell, J., Morris, A. D., Palmer, C. N. A., Elliott, P. & Caulfield, M. J., Oct 2018, In : Nature Genetics. 50, p. 1412-1425 14 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)
2016

Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease

Yaghootkar, H., Lotta, L. A., Tyrrell, J., Smit, R. A. J., Jones, S. E., Donnelly, L., Beaumont, R., Campbell, A., Tuke, M. A., Hayward, C., Ruth, K. S., Padmanabhan, S., Jukema, J. W., Palmer, C. C., Hattersley, A., Freathy, R. M., Langenberg, C., Wareham, N. J., Wood, A. R., Murray, A. & 5 others, Weedon, M. N., Sattar, N., Pearson, E., Scott, R. A. & Frayling, T. M., Aug 2016, In : Diabetes. 65, 8, p. 2448-2460 13 p.

Research output: Contribution to journalArticle

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44 Citations (Scopus)
182 Downloads (Pure)