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• 2014

  Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy

  McSorley, H. J., Blair, N. F., Smith, K. A., McKenzie, A. N. J. & Maizels, R. M., Sep 2014, In: Mucosal Immunology. 7, 5, p. 1068-1078 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Interleukin-33
  • Alternaria
  • Helminths
  • Ovalbumin
  • Hypersensitivity
  109 Citations (Scopus)

  37 Downloads (Pure)
• 2017

  HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33

  Osbourn, M., Soares, D. C., Vacca, F., Cohen, E. S., Scott, I. C., Gregory, W. F., Smyth, D. J., Toivakka, M., Kemter, A. M., le Bihan, T., Wear, M., Hoving, D., Filbey, K. J., Hewitson, J. P., Henderson, H., Gonzàlez-Cìscar, A., Errington, C., Vermeren, S., Astier, A. L., Wallace, W. A. & 4 others, Schwarze, J., Ivens, A. C., Maizels, R. M. & McSorley, H. J., 17 Oct 2017, In: Immunity. 47, 4, p. 739-751.e5 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Nematospiroides dubius
  • Alarmins
  • Interleukin-33
  • Helminths
  • Parasites
  53 Citations (Scopus)

  85 Downloads (Pure)
• 2018

  Basal Instinct: Persistence of Barrier Dysfunction

  Chauché, C. & McSorley, H. J., 16 Oct 2018, In: Immunity. 49, 4, p. 590-592 3 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Instinct
  • Ecosystem
  • Epigenomics
  • Chronic Disease
  • Epithelial Cells
  1 Citation (Scopus)

• Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion

  Smith, K. A., Löser, S., Varyani, F., Harcus, Y., McSorley, H. J., McKenzie, A. N. J. & Maizels, R. M., 5 Oct 2018, In: eLife. 7, p. 1-18 18 p., e38269.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Parasites
  • Helminths
  • Interleukin-17
  • Immunity
  • Alarmins
  11 Citations (Scopus)

  38 Downloads (Pure)
• 2017

  Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota

  McFarlane, A. J., McSorley, H. J., Davidson, D. J., Fitch, P. M., Errington, C., Mackenzie, K. J., Gollwitzer, E. S., Johnston, C. J. C., MacDonald, A. S., Edwards, M. R., Harris, N. L., Marsland, B. J., Maizels, R. M. & Schwarze, J., Oct 2017, In: Journal of Allergy and Clinical Immunology. 140, 4, p. 1068-1078.e6 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Helminths
  • Interferon Type I
  • Microbiota
  • Respiratory Syncytial Viruses
  • Virus Diseases
  34 Citations (Scopus)
• 2016

  Microbes and asthma: Opportunities for intervention

  Smits, H. H., Hiemstra, P. S., Prazeres Da Costa, C., Ege, M., Edwards, M., Garn, H., Howarth, P. H., Jartti, T., De Jong, E. C., Maizels, R. M., Marsland, B. J., McSorley, H. J., Müller, A., Pfefferle, P. I., Savelkoul, H., Schwarze, J., Unger, W. W. J., Von Mutius, E., Yazdanbakhsh, M. & Taube, C., Mar 2016, In: Journal of Allergy and Clinical Immunology. 137, 3, p. 690-697 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Immune System
  • Hygiene Hypothesis
  • Phenotype
  • Parasitic Diseases
  46 Citations (Scopus)
• 2017

  A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

  Johnston, C. J. C., Smyth, D. J., Kodali, R. B., White, M. P. J., Harcus, Y., Filbey, K. J., Hewitson, J. P., Hinck, C. S., Ivens, A., Kemter, A. M., Kildemoes, A. O., Le Bihan, T., Soares, D. C., Anderton, S. M., Brenn, T., Wigmore, S. J., Woodcock, H. V., Chambers, R. C., Hinck, A. P., McSorley, H. J. & 1 others, Maizels, R. M., 23 Nov 2017, In: Nature Communications. 8, p. 1-13 13 p., 1741.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Nematospiroides dubius
  • T-cells
  • parasites
  • Parasites
  • Helminths
  54 Citations (Scopus)

  43 Downloads (Pure)
• 2018

  Prostaglandin E₂ stimulates adaptive IL-22 production and promotes allergic contact dermatitis

  Robb, C. T., McSorley, H. J., Lee, J., Aoki, T., Yu, C., Crittenden, S., Astier, A., Felton, J. M., Parkinson, N., Ayele, A., Breyer, R. M., Anderton, S. M., Narumiya, S., Rossi, A. G., Howie, S. E., Guttman-Yassky, E., Weller, R. B. & Yao, C., Jan 2018, In: Journal of Allergy and Clinical Immunology. 141, 1, p. 152-162 11 p.

  Research output: Contribution to journal › Article › peer-review

  • interleukin-22
  • Allergic Contact Dermatitis
  • Prostaglandins E
  • Dinoprostone
  • Atopic Dermatitis
  15 Citations (Scopus)

• Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

  Maizels, R. M., Smits, H. H. & McSorley, H. J., 20 Nov 2018, In: Immunity. 49, 5, p. 801-818 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Helminths
  • Parasites
  • Immunity
  • Immune System Diseases
  • Immunomodulation
  61 Citations (Scopus)

  52 Downloads (Pure)
• 2019

  Macrophage migration inhibitory factor (MIF) is essential for type 2 effector cell immunity to an intestinal helminth parasite

  Filbey, K. J., Varyani, F., Harcus, Y., Hewitson, J. P., Smyth, D. J., McSorley, H. J., Ivens, A., Nylén, S., Rottenberg, M., Löser, S. & Maizels, R. M., 24 Oct 2019, In: Frontiers in Immunology. 10, 2375.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophage Migration-Inhibitory Factors
  • Helminths
  • Parasites
  • Immunity
  • indolepropanol phosphate
  3 Citations (Scopus)

  46 Downloads (Pure)
• 2017

  Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity

  Coakley, G., McCaskill, J. L., Borger, J. G., Simbari, F., Robertson, E., Millar, M., Harcus, Y., McSorley, H. J., Maizels, R. M. & Buck, A. H., 23 May 2017, In: Cell Reports. 19, 8, p. 1545-1557 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophages
  • Parasites
  • Extracellular Vesicles
  • Helminths
  • Macrophage Activation
  76 Citations (Scopus)

  45 Downloads (Pure)
• 2019

  Interleukin-33 in the developing lung—Roles in asthma and infection

  Johansson, K. & McSorley, H. J., Aug 2019, In: Pediatric Allergy and Immunology. 30, 5, p. 503-510 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Interleukin-33
  • Asthma
  • Infection
  • Lung
  • Lung Diseases
  15 Citations (Scopus)
• 2014

  Helminths in the hygiene hypothesis: Sooner or later?

  Maizels, R. M., Mcsorley, H. J. & Smyth, D. J., Jul 2014, In: Clinical and Experimental Immunology. 177, 1, p. 38-46 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hygiene Hypothesis
  • Helminths
  • Parasites
  • Immune System
  • Infection
  62 Citations (Scopus)

  41 Downloads (Pure)

• Helminths and Immunological Tolerance

  Johnston, C. J. C., McSorley, H. J., Anderton, S. M., Wigmore, S. J. & Maizels, R. M., 27 Jan 2014, In: Transplantation. 97, 2, p. 127-132 6 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Helminths
  • Parasites
  • Immunomodulation
  • Immunosuppression
  • Transplantation
  22 Citations (Scopus)

  37 Downloads (Pure)
• 2017

  Differential lower airway dendritic cell patterns May reveal distinct endotypes of RSV bronchiolitis

  Kerrin, A., Fitch, P., Errington, C., Kerr, D., Waxman, L., Riding, K., McCormack, J., Mehendele, F., McSorley, H., MacKenzie, K., Wronski, S., Braun, A., Levin, R., Theilen, U. & Schwarze, J., Jul 2017, In: Thorax. 72, 7, p. 620-627 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Bronchiolitis
  • Respiratory Syncytial Viruses
  • Dendritic Cells
  • Bronchoalveolar Lavage
  • Natural Killer Cells
  22 Citations (Scopus)
• 2016

  Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation

  Jackson-Jones, L. H., Duncan, S. M., Magalhaes, M. S., Campbell, S. M., Maizels, R. M., McSorley, H. J., Allen, J. E. & Bénézech, C., 1 Sep 2016, In: Nature Communications. 7, p. 1-14 14 p., 12651.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • secretions
  • infectious diseases
  • fats
  • lungs
  • Interleukin-33
  40 Citations (Scopus)

  41 Downloads (Pure)

• IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha

  Jackson-Jones, L. H., Rückerl, D., Svedberg, F., Duncan, S., Maizels, R. M., Sutherland, T. E., Jenkins, S. J., McSorley, H. J., Bénézech, C., MacDonald, A. S. & Allen, J. E., Oct 2016, In: European Journal of Immunology. 46, 10, p. 2311-2321 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Interleukin-4 Receptor alpha Subunit
  • Interleukin-33
  • Macrophages
  • Macrophage Activation
  • Pleural Cavity
  19 Citations (Scopus)

  47 Downloads (Pure)
• 2019

  Worms: Pernicious parasites or allies against allergies?

  McSorley, H. J., Chayé, M. A. M. & Smits, H. H., Jun 2019, In: Parasite Immunology. 41, 6, p. 1-13 13 p., e12574.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Helminths
  • Parasites
  • Hypersensitivity
  • Immunomodulation
  • Parasitic Diseases
  10 Citations (Scopus)

  42 Downloads (Pure)
• 2016

  Regulation of the host immune system by helminth parasites

  Maizels, R. M. & McSorley, H. J., Sep 2016, In: Journal of Allergy and Clinical Immunology. 138, 3, p. 666-675 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Helminths
  • Parasites
  • Immune System
  • Parasitic Diseases
  • Immunologic Monitoring
  182 Citations (Scopus)

  39 Downloads (Pure)

• Stage-specific proteomes from onchocerca ochengi, sister species of the human river blindness parasite, uncover adaptations to a nodular lifestyle

  Armstrong, S. D., Xia, D., Bah, G. S., Krishna, R., Ngangyung, H. F., La Course, E. J., McSorley, H. J., Kengne-Ouafo, J. A., Chounna-Ndongmo, P. W., Wanji, S., Enyong, P. A., Taylor, D. W., Blaxter, M. L., Wastling, J. M., Tanya, V. N. & Makepeace, B. L., Aug 2016, In: Molecular and Cellular Proteomics. 15, 8, p. 2554-2575 22 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Onchocerca
  • Ocular Onchocerciasis
  • Parasites
  • Proteome
  • Rivers
  15 Citations (Scopus)

  28 Downloads (Pure)
• 2017

  IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks

  Serrels, B., McGivern, N., Canel, M., Byron, A., Johnson, S. C., McSorley, H. J., Quinn, N., Taggart, D., Von Kreigsheim, A., Anderton, S. M., Serrels, A. & Frame, M. C., 5 Dec 2017, In: Science Signaling. 10, 508, p. 1-13 13 p., eaan8355.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-33
  • Immune Evasion
  • Focal Adhesion Protein-Tyrosine Kinases
  • Gene Regulatory Networks
  • Epithelial Cells
  26 Citations (Scopus)

• Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer

  Pastille, E., Frede, A., McSorley, H. J., Gräb, J., Adamczyk, A., Kollenda, S., Hansen, W., Epple, M., Buer, J., Maizels, R. M., Klopfleisch, R. & Westendorf, A. M., 22 Sep 2017, In: PLoS Pathogens. 13, 9, p. 1-22 22 p., e1006649.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Helminths
  • Colitis
  • Nematospiroides dubius
  • Colonic Neoplasms
  • Carcinogenesis
  20 Citations (Scopus)

  85 Downloads (Pure)
• 2016

  Novel O-linked methylated glycan antigens decorate secreted immunodominant glycoproteins from the intestinal nematode Heligmosomoides polygyrus

  Hewitson, J. P., Nguyen, D. L., van Diepen, A., Smit, C. H., Koeleman, C. A., McSorley, H. J., Murray, J., Maizels, R. M. & Hokke, C. H., Mar 2016, In: International Journal for Parasitology. 46, 3, p. 157-170 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Nematospiroides dubius
  • Polysaccharides
  • Glycoproteins
  • Antigens
  • Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase
  11 Citations (Scopus)

  39 Downloads (Pure)
• 2018

  TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus

  Smyth, D. J., Harcus, Y., White, M. P. J., Gregory, W. F., Nahler, J., Stephens, I., Toke-Bjolgerud, E., Hewitson, J. P., Ivens, A., McSorley, H. J. & Maizels, R. M., Apr 2018, In: International Journal for Parasitology. 48, 5, p. 379-385 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Nematospiroides dubius
  • Transforming Growth Factors
  • Parasites
  • Genes
  • Proteins
  13 Citations (Scopus)

  38 Downloads (Pure)
• 2014

  Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

  Buck, A. H., Coakley, G., Simbari, F., McSorley, H. J., Quintana, J. F., Le Bihan, T., Kumar, S., Abreu-Goodger, C., Lear, M., Harcus, Y., Ceroni, A., Babayan, S. A., Blaxter, M., Ivens, A. & Maizels, R. M., 25 Nov 2014, In: Nature Communications. 5, p. 1-11 11 p., 5488.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • parasites
  • Parasites
  • Exosomes
  • immunity
  • Transfer RNA
  339 Citations (Scopus)

  41 Downloads (Pure)