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Author

  • Thomas MacDonald

AB1029 Allopurinol and cardiovascular outcomes in patients with ischaemic heart disease (ALL-HEART) study: baseline characteristics of the randomised patient population

Mackenzie, I., Ford, I., Hawkey, C., Begg, A., Taggar, J., Struthers, A., Wei, L., Avery, A., Walker, A., Duce, S., Barr, R., Dumbleton, J. & Macdonald, T., 12 Jun 2018, In : Annals of the Rheumatic Diseases. 77, suppl. 2, p. 1631.1-1631 1 p.

Research output: Contribution to journalConference article

Acid-suppression medications and bacterial gastroenteritis: a population-based cohort study

Wei, L., Ratnayake, L., Phillips, G., McGuigan, C. C., Morant, S. V., Flynn, R. W., Mackenzie, I. S. & MacDonald, T. M., Jun 2017, In : British Journal of Clinical Pharmacology. 83, 6, p. 1298-1308 11 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
179 Downloads (Pure)

A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism

Parthasarathy, H. K., Menard, J., White, W. B., Young, W. F., Williams, G. H., Williams, B., Miguel Ruilope, L., McInnes, G. T., Connell, J. M. & MacDonald, T. M., May 2011, In : Journal of Hypertension. 29, 5, p. 980-990 11 p.

Research output: Contribution to journalArticle

135 Citations (Scopus)

Aliskiren and the calcium channel blocker amlodipine combination as an initial treatment strategy for hypertension control (ACCELERATE): a randomised, parallel-group trial

Brown, M. J., McInnes, G. T., Papst, C. C., Zhang, J. & MacDonald, T. M., 22 Jan 2011, In : Lancet. 377, 9762, p. 312-320 9 p.

Research output: Contribution to journalArticle

132 Citations (Scopus)

Allopurinol treatment adversely impacts left ventricular mass regression in patients with well-controlled hypertension

Gingles, C., Symon, R., Gandy, S., Struthers, A., Houston, G., MacDonald, T., Lang, C., Donnan, P. & George, J., Dec 2019, In : Journal of Hypertension. 37, 12, p. 2481-2489 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
144 Downloads (Pure)

An audit of the diagnostic coding of pancreatitis of 331 patients in Tayside, Scotland

Ghorbanifard, Z., Daryabakhsh, A. S., Wei, L., Murphy, M. J. & MacDonald, T. M., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement s3, p. 398-398 1 p., 859.

Research output: Contribution to journalMeeting abstract

An efficient and inexpensive system for the distribution and tracking of investigational medicinal products in streamlined safety trials

Flynn, R. W., McDonnell, P. G., Mackenzie, I. S., Wei, L. & MacDonald, T. M., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement s3, p. 124-124 1 p., 263.

Research output: Contribution to journalMeeting abstract

7 Citations (Scopus)
Open Access
File
1 Citation (Scopus)
193 Downloads (Pure)

A pilot study to investigate the supply of investigational medicinal product to patients via mail in a streamlined safety study

Flynn, R. W., Saywood, W., Mackenzie, I. S., Wei, L. & MacDonald, T. M., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement S3, p. 124-125 2 p., 264.

Research output: Contribution to journalMeeting abstract

Appendicectomy is associated with increased pregnancy rate: a cohort study

Wei, L., Macdonald, T. M. & Shimi, S. M., Dec 2012, In : Annals of Surgery. 256, 6, p. 1039-1044 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Assessing therapies in rare disease patients: re-evaluating the n-of-one crossover design

Wang, J., Morant, S., Ford, I., Flynn, R. W., MacDonald, T. M. & Wei, L., Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement s3, p. 126-126 1 p., 267.

Research output: Contribution to journalMeeting abstract

Association between appendicectomy in females and subsequent pregnancy rate: a cohort study

Wei, L., MacDonald, T. & Shimi, S., Aug 2012, In : Fertility and Sterility. 98, 2, p. 401-405 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Association between cardiovascular events and sodium-containing effervescent, dispersible, and soluble drugs: nested case-control study

George, J., Majeed, W., Mackenzie, I. S., MacDonald, T. M. & Wei, L., 26 Nov 2013, In : BMJ. 347, f6954.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Can microalbuminuria identify silent "pancardiac" target organ damage in a non-diabetic primary prevention population?

Nadir, A., Rekhraj, S., Davidson, J., MacDonald, T. M., Lang, C. & Struthers, A. D., Jun 2011, In : Heart. 97, p. A35-A35 1 p.

Research output: Contribution to journalBook/Film/Article review

Cardiovascular risk associated with sodium-containing medicines

Wei, L., Mackenzie, I. S., MacDonald, T. M. & George, J., Nov 2014, In : Expert Opinion on Drug Safety. 13, 11, p. 1515-1523 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
11 Citations (Scopus)

Cardiovascular Safety of Lumiracoxib: A Meta-Analysis of Randomised Controlled Trials in Patients with Osteoarthritis

Mackenzie, I. S., Wei, L. & MacDonald, T. M., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, s1, p. S354-S354 1 p.

Research output: Contribution to journalBook/Film/Article review

6 Citations (Scopus)

Cardiovascular Safety of Prucalopride in Patients with Chronic Constipation: A Multinational Population-Based Cohort Study

Gilsenan, A., Fortuny, J., Cainzos-Achirica, M., Cantero, O. F., Flynn, R. W. V., Garcia-Rodriguez, L., Harding, A., Kollhorst, B., Karlsson, P., Linnér, L., MacDonald, T. M., Odsbu, I., Plana, E., Ruigómez, A., Schink, T., Ziemiecki, R. & Andrews, E. B., Oct 2019, In : Drug Safety. 42, 10, p. 1179-1190 12 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
70 Downloads (Pure)

Changing face of multiple sclerosis in the United kingdom 1990-2010: an incidence and prevalence study

Mackenzie, I. S., Morant, S. V., Bloomfield, G. A., Macdonald, T. M. & O'Riordan, J. I., Nov 2013, In : Journal of Neurology, Neurosurgery and Psychiatry. 84, 11, 1 p., ABN Abstracts 027.

Research output: Contribution to journalMeeting abstract

6 Citations (Scopus)

Chronotherapy in hypertension: the devil is in the details

Guthrie, G., TIME study Steering Committee, Poulter, N., Macdonald, T., Ford, I., Mackenzie, I., Findlay, E., Williams, B., Brown, M., Lang, C. & Webb, D., 21 Apr 2020, In : European Heart Journal. 41, 16, p. 1606-1607 2 p.

Research output: Contribution to journalComment/debate

Open Access
File
16 Downloads (Pure)
3 Citations (Scopus)

Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double-Blind Randomized Controlled Trial

MacDonald, T. M., Williams, B., Webb, D. J., Morant, S., Caulfield, M., Cruickshank, J. K., Ford, I., Sever, P., Mackenzie, I. S., Padmanabhan, S., McCann, G. P., Salsbury, J., McInnes, G., Brown, M. J. & for The British Hypertension Society Programme of Prevention And Treatment of Hypertension With Algorithm‐based Therapy (PATHWAY), Nov 2017, In : Journal of the American Heart Association. 6, 11, p. 1-28 28 p., e006986.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
169 Downloads (Pure)

Comparison of single and combination diuretics on glucose tolerance (PATHWAY-3): protocol for a randomised double-blind trial in patients with essential hypertension

Brown, M. J., Williams, B., MacDonald, T. M., Caulfield, M., Cruickshank, J. K., McInnes, G., Sever, P., Webb, D. J., Salsbury, J., Morant, S. & Ford, I., 7 Aug 2015, In : BMJ Open. 5, 8, 8 p., e008086.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
191 Downloads (Pure)

Co-prescription of co-trimoxazole and spironolactone in elderly patients

Wei, L., MacDonald, T. M. & Mackenzie, I. S., 12 Sep 2011, In : BMJ. 343, 7823, p. - 2 p., d5656.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Does offering an incentive payment improve recruitment to clinical trials and increase the proportion of socially deprived and elderly participants?

Jennings, C. G., MacDonald, T. M., Wei, L., Brown, M. J., McConnachie, L. & Mackenzie, I. S., 7 Mar 2015, In : Trials. 16, 9 p., 80.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
124 Downloads (Pure)
Open Access
File
112 Downloads (Pure)

Drop-out rates in patients with and without screening period in the SCOT Trial

Wei, L., MacDonald, T. M. & SCOT Study Grp Collaborators, Aug 2012, In : Pharmacoepidemiology and Drug Safety. 21, Supplement S3, p. 87-87 1 p., 183.

Research output: Contribution to journalMeeting abstract

4 Citations (Scopus)

Effectiveness of newspaper advertising for patient recruitment into a clinical trial

Hapca, A., Jennings, C. G., Wei, L., Wilson, A., MacDonald, T. M. & Mackenzie, I. S., Jun 2014, In : British Journal of Clinical Pharmacology. 77, 6, p. 1064-1072 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Effectiveness of statins in chronic kidney disease

Sheng, X., Macdonald, T. M., Wei, L. & Murphy, M. J., Jul 2012, In : QJM : an International Journal of Medicine. 105, 7, p. 641-648 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
51 Citations (Scopus)

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

Brown, M. J., Williams, B., Morant, S. V., Webb, D. J., Caulfield, M. J., Cruickshank, J. K., Ford, I., McInnes, G., Sever, P., Salsbury, J., Mackenzie, I. S., Padmanabhan, S., MacDonald, T. M. & for the British Hypertension Society's Prevention, Treatment of Hypertension with Algorithm-based Therapy (PATHWAY) Studies Group, Feb 2016, In : The Lancet: Diabetes and Endocrinology. 4, 2, p. 136-147 12 p.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
140 Downloads (Pure)

Effect of statins on total cholesterol concentrations, cardiovascular morbidity, and all-cause mortality in chronic obstructive pulmonary disease: a population-based cohort study

Sheng, X., Murphy, M. J., MacDonald, T. M., Schembri, S., Simpson, W., Winter, J., Winter, J. H. & Wei, L., 2012, In : Clinical Pharmacology & Therapeutics. 34, 2, p. 374-384 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
17 Citations (Scopus)
Open Access
File
8 Citations (Scopus)
321 Downloads (Pure)

Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies

Williams, B., MacDonald, T. M., Morant, S. V., Webb, D. J., Sever, P., McInnes, G. T., Ford, I., Cruickshank, J. K., Caulfield, M. J., Padmanabhan, S., Mackenzie, I. S., Salsbury, J. & Brown, M. J., 1 Jun 2018, In : The Lancet Diabetes and Endocrinology. 6, 6, p. 464-475 12 p.

Research output: Contribution to journalArticle

Open Access
File
59 Citations (Scopus)
108 Downloads (Pure)

Erratum: The British Society for Rheumatology Guideline for the Management of Gout

Hui, M., Carr, A., Cameron, S., Davenport, G., Doherty, M., Forrester, H., Jenkins, W., Jordan, K. M., Mallen, C. D., MacDonald, T., Nuki, G., Pywell, A., Zhang, W. & Roddy, E., 1 Jul 2017, In : Rheumatology. 56, 7, p. 1246 1 p.

Research output: Contribution to journalArticle

Estimated GFR reporting is associated with decreased nonsteroidal anti-inflammatory drug prescribing and increased renal function

Wei, L., MacDonald, T. M., Jennings, C., Sheng, X., Flynn, R. W. & Murphy, M. J., Jul 2013, In : Kidney International. 84, 1, p. 174-178 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Evaluation of pregnancy outcomes in patients with multiple sclerosis after fingolimod exposure

Geissbühler, Y., Vile, J., Koren, G., Guennec, M., Butzkueven, H., Tilson, H., MacDonald, T. M. & Hellwig, K., 2018, In : Therapeutic Advances in Neurological Disorders. 11, p. 1-9 9 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
136 Downloads (Pure)

Exaggerated exercise blood pressure response and future cardiovascular disease

Tzemos, N., Lim, P. O., Mackenzie, I. S. & Macdonald, T. M., Nov 2015, In : Journal of Clinical Hypertension . 17, 11, p. 837-844 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

High-potency statin and ezetimibe use and mortality in survivors of an acute myocardial infarction: a population-based study

Pauriah, M., Elder, D. H. J., Ogston, S., Noman, A. Y. S., Majeed, A., Wyatt, J. C., Choy, A-M., MacDonald, T. M., Struthers, A. D. & Lang, C. C., 2014, In : Heart. 100, 11, p. 867-872 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

High Sensitivity Cardiac Troponin T is Associated with Silent Cardiac Target Organ Damage in Asymptomatic Primary Prevention Patients

Nadir, M. A., Dow, E., Lang, C. C., Davidson, J., MacDonald, T. & Struthers, A. D., 22 Nov 2011, In : Circulation. 124, 21, p. - 2 p.

Research output: Contribution to journalArticle

Home blood pressure monitoring

George, J. & MacDonald, T., 2015, In : European Cardiology Review. 10, 2, p. 95-101 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Hypertension in octogenarians: treatment strategies and challenges

Mackenzie, I. S. & MacDonald, T. M., 1 Jan 2011, In : European Cardiology. 7, 1, p. 25-28 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Hypertriglyceridemia and acute pancreatitis

Murphy, M. J., Sheng, X., MacDonald, T. M. & Wei, L., Aug 2011, In : Pharmacoepidemiology and Drug Safety. 20, S1, p. S257-S257 1 p., 590.

Research output: Contribution to journalSpecial issue

6 Citations (Scopus)

Hypertriglyceridemia and acute pancreatitis

Murphy, M. J., Sheng, X., MacDonald, T. M. & Wei, L., 28 Jan 2013, In : JAMA Internal Medicine. 173, 2, p. 162-164 3 p.

Research output: Contribution to journalLetter

58 Citations (Scopus)

Ibuprofen and Paracetamol: Acceptably Safe for All?

Pigazzani, F., Mackenzie, I. & MacDonald, T. M., Nov 2018, In : Drug Safety. 41, 11, p. 999-1001 3 p.

Research output: Contribution to journalComment/debate

Open Access
File
2 Citations (Scopus)
154 Downloads (Pure)