Find Research Outputs

Search in all content

Filters for Research Outputs

Search concepts
Selected filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Christopher Barratt

2-APB-potentiated channels amplify CatSper-induced Ca signals in human sperm

Lefièvre, L., Nash, K., Mansell, S., Costello, S., Punt, E., Correia, J., Morris, J., Kirkman-Brown, J., Wilson, S. M., Barratt, C. L. R. & Publicover, S., Dec 2012, In : Biochemical Journal. 448, 2, p. 189-200 12 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Absolute SILAC-compatible expression strain allows SUMO-2 copy number determination in clinical samples

Matic, I., Jaffray, E. G., Oxenham, S. K., Groves, M. J., Barratt, C. L. R., Tauro, S., Stanley-Wall, N. R. & Hay, R. T., Oct 2011, In : Journal of Proteome Research. 10, 10, p. 4869-4875 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

A Dolce & Gabbana model in every ART clinic?

Barratt, C. L. R., Sep 2018, In : Molecular Human Reproduction. 24, 9, p. 431-432 2 p.

Research output: Contribution to journalEditorial

Open Access
File
2 Citations (Scopus)
81 Downloads (Pure)

A phenotypic screening platform utilising human spermatozoa identifies compounds with contraceptive activity

Gruber, F. S., Johnston, Z. C., Barratt, C. L. R. & Andrews, P. D., 28 Jan 2020, In : eLife. 9, 14 p., e51739.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
6 Downloads (Pure)

A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channels

Fernandes, G., Dasai, N., Kozlova, N., Mojadadi, A., Gall, M., Drew, E., Barratt, E., Madamidola, O. A., Brown, S. G., Milne, A. M., Martins Da Silva, S. J., Whalley, K. M., Barratt, C. L. R. & Jovanovic, A., Feb 2016, In : Human Reproduction. 31, 2, p. 287-297 11 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
127 Downloads (Pure)

Ca2+ signals generated by CatSper and Ca2+ stores regulate different behaviors in human sperm

Alasmari, W., Costello, S., Correia, J., Oxenham, S. K., Morris, J., Fernandes, L., Ramalho-Santos, J., Kirkman-Brown, J., Michelangeli, F., Publicover, S. & Barratt, C. L. R., 1 Mar 2013, In : Journal of Biological Chemistry. 288, 9, p. 6248-58 11 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Chloride channels join the sperm 'channelome'

Publicover, S. J. & Barratt, C. L. R., Jun 2012, In : Journal of Physiology. 590, 11, p. 2553-2554 2 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Clarification of scope for Human Reproduction and Molecular Human Reproduction

Petraglia, F., Barratt, C. L. R. & Evers, J. L. H., 1 Sep 2015, In : Human Reproduction Update. 21, 5, p. 559 1 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)

Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity

Tardif, S., Madamidola, O. A., Brown, S. G., Frame, L., Lefièvre, L., Wyatt, P. G., Barratt, C. L. R. & Martins Da Silva, S. J., 10 Oct 2014, In : Human Reproduction. 29, 10, p. 2123-2135 13 p.

Research output: Contribution to journalArticle

Open Access
File
24 Citations (Scopus)
160 Downloads (Pure)

Complex CatSper-dependent and independent [Ca2+] signaling induced by human follicular fluid

Brown, S. G., Costello, S., Kelly, M., Ramalingam, M., Drew, E., Publicover, S. J., Barratt, C. & Martins Da Silva, S., 1 Oct 2017, In : Human Reproduction. 32, 10, p. 1995-2006 12 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
128 Downloads (Pure)

Continuous behavioural 'switching' in human spermatozoa and its regulation by Ca2+-mobilising stimuli

Achikanu, C., Correia, J., Guidobaldi, H., Giojalas, L., L. R. Barratt, C., Da Silva, S. M. & Publicover, S., Aug 2019, In : Molecular Human Reproduction. 25, 8, p. 423-432 10 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
111 Downloads (Pure)

Controlling how sperm swim: Ca2+signals, Ca2+stores and Ca2+channels

Publicover, S., Correia, J., Alasmari, W. & Barratt, C., 2013, In : Human Reproduction. 28, S1, p. i20-i21 2 p.

Research output: Contribution to journalMeeting abstract

Current concepts and unresolved questions in human sperm cumulus and zona interaction

De Jonge, C. J. & Barratt, C. L. R., 25 May 2017, The Sperm Cell: Production, Maturation, Fertilization, Regeneration. UNESCO/Cambridge University Press, p. 152-156 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF

Brown, S. G., Publicover, S. J., Mansell, S., Lishko, P. V., Williams, H. L., Ramalingam, M., Wilson, S. M., Barratt, C. L. R., Sutton, K. A. & Da Silva, S. M., 15 Jun 2016, In : Human Reproduction. 31, 6, p. 1147-1157 11 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
160 Downloads (Pure)

Diagnostic tools in male infertility-the question of sperm dysfunction

Barratt, C. L. R., Mansell, S., Beaton, C., Tardif, S. & Oxenham, S. K., Jan 2011, In : Asian Journal of Andrology. 13, 1, p. 53-58 6 p.

Research output: Contribution to journalReview article

61 Citations (Scopus)

DPY19L2, its mutation in about half globozoospermia

Koscinski, I., Elinati, E., Fossard, C., Kuentz, P., Kilani, Z., Demirol, A., Gurgan, T., Schmitt, F., de la Calle, J. V., Iqbal, N., Louanjli, N., Pasquier, M., Carre-Pigeon, F., Muller, J., Barratt, C. & Viville, S., 2011, In : Human Reproduction. 26, S1, p. i281 1 p., P-412.

Research output: Contribution to journalBook/Film/Article review

DPY19L2 Deletion as a Major Cause of Globozoospermia

Koscinski, I., Ellnati, E., Fossard, C., Redin, C., Muller, J., de la Calle, J. V., Schmitt, F., Ben Khelifa, M., Ray, P., Kilani, Z., Barratt, C. L. R. & Viville, S., 11 Mar 2011, In : American Journal of Human Genetics. 88, 2011, p. 344-350 7 p.

Research output: Contribution to journalArticle

111 Citations (Scopus)

Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem

Martins Da Silva, S. J., Brown, S. G., Sutton, K., King, L. V., Ruso, H., Gray, D. W., Wyatt, P. G., Kelly, M. C., Barratt, C. L. R. & Hope, A. G., May 2017, In : Human Reproduction. 32, 5, p. 974-984 11 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
163 Downloads (Pure)

Education, education, education: now more than ever?

Andersen, C. Y., Kristensen, S. G., Mamsen, L. S. & Barratt, C., 1 Aug 2018, In : Molecular Human Reproduction. 24, 8, p. 426-429 4 p.

Research output: Contribution to journalArticle

Open Access
File
72 Downloads (Pure)

Erratum - DPY19L2 Deletion as a Major Cause of Globozoospermia

Koscinski, I., Ellnati, E., Fossard, C., Redin, C., Muller, J., de la Calle, J. V., Schmitt, F., Ben Khelifa, M., Ray, P. F., Kilani, Z., Barratt, C. L. R. & Viville, S., 8 Apr 2011, In : American Journal of Human Genetics. 88, 4, p. 517 1 p.

Research output: Contribution to journalArticle

ESHRE special interest group for andrology basic semen analysis course: a continued focus on accuracy, quality, efficiency and clinical relevance

Barratt, C. L. R., Bjoerndahl, L., Menkveld, R. & Mortimer, D., Dec 2011, In : Human Reproduction. 26, 12, p. 3207-3212 6 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Fertility preservation in men with cancer

Tournaye, H., Dohle, G. R. & Barratt, C. L. R., 4 Oct 2014, In : Lancet. 384, 9950, p. 1295-1301 7 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Homozygous in-frame deletion in CATSPERE in a man producing spermatozoa with loss of CatSper function and compromised fertilizing capacity

Brown, S. G., Miller, M. R., Lishko, P. V., Lester, D. H., Publicover, S. J., Barratt, C. L. R. & Martins Da Silva, S., 1 Oct 2018, In : Human Reproduction. 33, 10, p. 1812-1816 5 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
88 Downloads (Pure)

'How to count sperm properly': checklist for acceptability of studies based on human semen analysis

Björndahl, L., Barratt, C. L. R., Mortimer, D. & Jouannet, P., Feb 2016, In : Human Reproduction. 31, 2, p. 227-232 6 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Human sperm ion channel (dys)function: implications for fertilization

Brown, S. G., Publicover, S. J., Barratt, C. & Martins Da Silva, S., Nov 2019, In : Human Reproduction Update. 25, 6, p. 758-776 19 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
50 Downloads (Pure)

Importance of β-defensins in sperm function

Dorin, J. R. & Barratt, C. L. R., Sep 2014, In : Molecular Human Reproduction. 20, 9, p. 821-826 6 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Improved sperm function / activity

Barratt, C. & Wyatt, P., 18 Apr 2013, IPC No. A61K31/519; A61P15/00; A61K31/52; A61K31/437; A61K45/00; A61K31/551; A61K39/395; A61K31/47, Patent No. WO2013054111 A1

Research output: Patent

In Memoriam: Lynn R Fraser

Aitken, R. J. & Barratt, C. L. R., 24 May 2020, In : Andrology. 8, 3, p. 532-534 3 p.

Research output: Contribution to journalArticle

Intracellular translocation and differential accumulation of cell-penetrating peptides in bovine spermatozoa: evaluation of efficient delivery vectors that do not compromise human sperm motility

Jones, S., Lukanowska, M., Suhorutsenko, J., Oxenham, S., Barratt, C., Publicover, S., Copolovici, D. M., Langel, U. & Howl, J., Jul 2013, In : Human Reproduction. 28, 7, p. 1874-1889 16 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Is there a robust future for research in reproduction?

Barratt, C. L. R., Jan 2016, In : Molecular Human Reproduction. 22, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Lessons in Andrology: Thoughts for a Young Andrologist

Barratt, C. L. R., 26 Oct 2016, In : Andrology. 4, 6, p. 987-989 3 p.

Research output: Contribution to journalEditorial

Male fertility: a window on the health of this generation and the next

Barratt, C. L. R., Anderson, R. A. & De Jonge, C., Nov 2019, In : Reproductive BioMedicine Online. 39, 5, p. 721-723 3 p.

Research output: Contribution to journalEditorial

MHR celebration issue in tribute to Professor Sir Robert Edwards

Barratt, C. L. R., Dec 2013, In : Molecular Human Reproduction. 19, 12, p. 783-784 2 p.

Research output: Contribution to journalEditorial

Novel pharmacological actions of Trequinsin Hydrochloride improve human sperm cell motility and function

McBrinn, R. C., Fraser, J., Hope, A. G., Gray, D. W., Barratt, C. L. R., Martins da Silva, S. J. & Brown, S. G., Dec 2019, In : British Journal of Pharmacology. 176, 23, p. 4521-4536 16 p.

Research output: Contribution to journalArticle

Open Access
File
56 Downloads (Pure)

p,p'-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations

Tavares, R. S., Mansell, S., Barratt, C. L. R., Wilson, S. M., Publicover, S. J. & Ramalho-Santos, J., Dec 2013, In : Human Reproduction. 28, 12, p. 3167-3177 11 p.

Research output: Contribution to journalArticle

Open Access
File
47 Citations (Scopus)
159 Downloads (Pure)

Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice

Zhou, Y. S., Webb, S., Lettice, L., Tardif, S., Kilanowski, F., Tyrrell, C., Macpherson, H., Semple, F., Tennant, P., Baker, T., Hart, A., Devenney, P., Perry, P., Davey, T., Barran, P., Barratt, C. L. & Dorin, J. R., 24 Oct 2013, In : PLoS Genetics. 9, 10, p. 1-13 13 p., e1003826.

Research output: Contribution to journalArticle

Open Access
File
45 Citations (Scopus)
116 Downloads (Pure)

Patch clamp studies of human sperm under physiological ionic conditions reveal three functionally and pharmacologically distinct cation channels

Mansell, S. A., Publicover, S. J., Barratt, C. L. R. & Wilson, S. M., May 2014, In : Molecular Human Reproduction. 20, 5, p. 392-408 17 p.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
164 Downloads (Pure)
Open Access

Preface

De Jonge, C. J. & Barratt, C. L. R., 25 May 2017, The Sperm Cell: Production, Maturation, Fertilization, Regeneration. UNESCO/Cambridge University Press, p. xiii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

2 Citations (Scopus)
1 Citation (Scopus)

Proposal of guidelines for the appraisal of SEMen QUAlity studies (SEMQUA)

Special Interest Group in Andrology of the European Society of Human Reproduction and Embriology, Sánchez-Pozo, M. C., Mendiola, J., Serrano, M., Mozas, J., Björndahl, L., Menkveld, R., Lewis, S. E. M., Mortimer, D., Jørgensen, N., Barratt, C. L. R., Fernández, M. F. & Castilla, J. A., Jan 2013, In : Human Reproduction. 28, 1, p. 10-21 12 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Protect us from poor-quality medical research

ESHRE Capri Workshop Group, 1 May 2018, In : Human Reproduction. 33, 5, p. 770-776 7 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
104 Downloads (Pure)

Reproductive biology: progesterone's gateway into sperm (vol 471, pg 313, 2011). Clarification

Publicover, S. & Barratt, C., 31 Mar 2011, In : Nature. 471, 7340, p. 589-589 1 p.

Research output: Contribution to journalArticle

Reproductive biology: progesterone's gateway into sperm

Publicover, S. & Barratt, C., 17 Mar 2011, In : Nature. 471, 7338, p. 313-314 2 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

'Single cell analysis in development' special series

Barratt, C. L. R., Mar 2016, In : Molecular Human Reproduction. 22, 3, p. 159 1 p.

Research output: Contribution to journalEditorial

Single-cell analysis of [Ca2+]i signalling in sub-fertile men: characteristics and relation to fertilization outcome

Kelly, M. C., Brown, S. G., Costello, S. M., Ramalingam, M., Drew, E., Publicover, S. J., Barratt, C. L. R. & Martins Da Silva, S., Jun 2018, In : Human Reproduction. 33, 6, p. 1023-1033 11 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
81 Downloads (Pure)

Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa

Williams, H. L., Mansell, S., Alasmari, W., Brown, S. G., Wilson, S. M., Sutton, K. A., Miller, M. R., Lishko, P. V., Barratt, C. L. R., Publicover, S. J. & Martins da Silva, S., Dec 2015, In : Human Reproduction. 30, 12, p. 2737-2746 10 p.

Research output: Contribution to journalArticle

Open Access
File
37 Citations (Scopus)
156 Downloads (Pure)

Sperm are promiscuous and CatSper is to blame...

Barratt, C. L. R. & Publicover, S. J., 4 Apr 2012, In : EMBO Journal. 31, 7, p. 1624-1626 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Sperm motility: things are moving in the lab!

Publicover, S. J. & Barratt, C. L. R., Aug 2011, In : Molecular Human Reproduction. 17, 8, p. 453-456 4 p.

Research output: Contribution to journalEditorial

12 Citations (Scopus)

Sperm selection in natural conception: what can we learn from Mother Nature to improve assisted reproduction outcomes?

Sakkas, D., Ramalingam, M., Garrido, N. & Barratt, C., 2015, In : Human Reproduction Update. 21, 6, p. 711-726 16 p.

Research output: Contribution to journalArticle

Open Access
File
69 Citations (Scopus)
136 Downloads (Pure)