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• Activation of Nrf2 and cellular inflammatory response by hypochlorous acid

  Woods, C. G., Andersen, M. E., Zhang, Q., Thomas, R. S., Henderson, C. J., Wolf, C. R. & Pi, J., 2007, In: Free Radical Biology and Medicine. 43, p. S160-S160 1 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

  9 Citations (Scopus)

• Activation of Nrf2 signaling as a common treatment of neurodegenerative diseases

  Dinkova-Kostova, A. T. & Kazantsev, A. G., Apr 2017, In: Neurodegenerative Disease Management. 7, 2, p. 97-100 4 p.

  Research output: Contribution to journal › Editorial

  Open Access

  File
  12 Citations (Scopus)

  204 Downloads (Pure)

• Activation of Nrf2 signaling augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

  Olagnier, D., Lababidi, R. R., Bel Hadj, S., Sze, A., Liu, Y., Dayalan Naidu, S., Ferrari, M., Jiang, Y., Chiang, C., Beljanski, V., Goulet, M-L., Knatko, E. V., Dinkova-Kostova, A. T., Hiscott, J. & Lin, R., 2 Aug 2017, In: Molecular Therapy. 25, 8, p. 1900-1916 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  51 Citations (Scopus)

  210 Downloads (Pure)

• Activation of oestrogen receptor α induces a novel form of LTP at hippocampal temporoammonic-CA1 synapses

  Clements, L. & Harvey, J., 11 Feb 2020, In: British Journal of Pharmacology. 177, 3, p. 642-655 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  11 Citations (Scopus)

  134 Downloads (Pure)

• Activation of peroxisome proliferator-activated receptor δ stimulates the proliferation of human breast and prostate cancer cell lines

  Stephen, R. L., Gustafsson, M. C. U., Jarvis, M., Tatoud, R., Marshall, B. R., Knight, D., Ehrenborg, E., Harris, A. L., Wolf, C. R. & Palmer, C. N. A., May 2004, In: Cancer Research. 64, 9, p. 3162-3170 9 p.

  Research output: Contribution to journal › Article › peer-review
  151 Citations (Scopus)

• Activation of peroxisome proliferator activator receptor beta/delta in the skin induces IL1 and STAT3 signalling

  Romanowska, M., Reilly, L., Palmer, C. & Foerster, J., Apr 2010, In: British Journal of Dermatology. 162, 4, p. 916-917 2 p.

  Research output: Contribution to journal › Special issue › peer-review

• Activation of phosphorylase kinase from rabbit skeletal muscle by calmodulin and troponin

  Cohen, P., Picton, C. & Klee, C. B., 1 Aug 1979, In: FEBS Letters. 104, 1, p. 25-30 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  47 Citations (Scopus)

• Activation of PPAR beta/delta Causes a Psoriasis-Like Skin Disease In Vivo

  Romanowska, M., Reilly, L., Palmer, C. N. A., Gustafsson, M. C. U. & Foerster, J., 16 Mar 2010, In: PLoS ONE. 5, 3, p. - 14 p., e9701.

  Research output: Contribution to journal › Article › peer-review
  72 Citations (Scopus)

• Activation of PPAR delta causes a psoriasis-like skin disease in vivo

  Romanowska, M., Niteshwaran, S., Palmer, C. & Foerster, J., Dec 2008, In: British Journal of Dermatology. 159, 6, p. 1398-1398 1 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• Activation of PPAR delta in vivo is sufficient to cause psoriasis-like disease and replicates transcriptional dysregulation

  Romanowska, M., Palmer, C. N. & Foerster, J. P., Apr 2009, In: British Journal of Dermatology. 160, 4, p. 902-903 2 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• Activation of PPAR delta in vivo replicates major elements of psoriasis

  Romanowska, M., Reilly, L., Palmer, C. & Foerster, J., Sept 2009, In: Journal of Investigative Dermatology. 129, s2, p. S89-S89 1 p.

  Research output: Contribution to journal › Special issue › peer-review

• Activation of protein kinase B β and γ isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: Comparison with protein kinase B α

  Walker, K. S., Deak, M., Paterson, A., Hudson, K., Cohen, P. & Alessi, D. R., 1 Apr 1998, In: Biochemical Journal. 331, 1, p. 299-308 10 p.

  Research output: Contribution to journal › Review article › peer-review
  26 Citations (Scopus)

• Activation of protein kinase C modulates the expression of the T3/T cell antigen receptor complex on human T lymphocytes

  Davies, A. A., Cantrell, D. A. & Crumpton, M. J., 1 Oct 1985, In: Bioscience Reports. 5, 10-11, p. 867-876 10 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses

  Wu, G., Murugesan, G., Nagala, M., McCraw, A., Haslam, S. M., Dell, A. & Crocker, P. R., 1 Jun 2021, In: Wellcome Open Research. 6, 30 p., 134.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Citation (Scopus)

  18 Downloads (Pure)

• Activation of sensory neurons in the arthritic joint

  Grubb, B. D., 1 Dec 2004, Osteoarthritic Joint Pain. Chadwick, D. J. & Goode, J. (eds.). Wiley, Vol. 260. p. 28-48 21 p. (Novartis Foundation Symposium; vol. 260).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  18 Citations (Scopus)

• Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

  Kobayashi, T. & Cohen, P., 15 Apr 1999, In: Biochemical Journal. 339, 2, p. 319-328 10 p.

  Research output: Contribution to journal › Article › peer-review
  462 Citations (Scopus)

• Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); Comparison of the specificities of SAPK3 and SAPK2 (RK/p38)

  Cuenda, A., Cohen, P., Buée-Scherrer, V. & Goedert, M., 15 Jan 1997, In: EMBO Journal. 16, 2, p. 295-305 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Citations (Scopus)

• Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

  Emmerich, C. H., Ordureau, A., Strickson, S., Arthur, J. S. C., Pedrioli, P. G. A., Komander, D. & Cohen, P., 17 Sept 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 38, p. 15247-15252 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  314 Citations (Scopus)

  164 Downloads (Pure)

• Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation

  Canedo, C. S., Demeulder, B., Ginion, A., Bayascas, J. R., Balligand, J-L., Alessi, D. R., Vanoverschelde, J-L., Beauloye, C., Hue, L. & Bertrand, L., Apr 2010, In: AJP - Endocrinology and Metabolism (Endocrinology and Metabolism. 298, 4, p. E761-E769 9 p.

  Research output: Contribution to journal › Article › peer-review
  50 Citations (Scopus)

• Activation of the cryptic DNA binding function of mutant forms of p53

  Hupp, T. R., Meek, D. W., Midgley, C. A. & Lane, D. P., 11 Jul 1993, In: Nucleic Acids Research. 21, 14, p. 3167-3174 8 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains

  Mallery, D. L., Vandenberg, C. J. & Hiom, K., 16 Dec 2002, In: EMBO Journal. 21, 24, p. 6755-6762 8 p.

  Research output: Contribution to journal › Article › peer-review
  240 Citations (Scopus)

• Activation of the Innate Immune Checkpoint CLEC5A on Myeloid Cells in the Absence of Danger Signals Modulates Macrophages' Function but Does Not Trigger the Adaptive T Cell Immune Response

  Tosiek, M. J., Groesser, K., Pekcec, A., Zwirek, M., Murugesan, G. & Borges, E., 25 Feb 2022, In: Journal of Immunology Research. 2022, p. 1-22 22 p., 9926305.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Citation (Scopus)

  33 Downloads (Pure)

• Activation of the MAP kinase homologue RK requires the phosphorylation of Thr-180 and Tyr-182 and both residues are phosphorylated in chemically stressed KB cells

  Doza, Y. N., Cuenda, A., Thomas, G. M., Cohen, P. & Nebreda, A. R., 8 May 1995, In: FEBS Letters. 364, 2, p. 223-228 6 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Activation of the MAP kinase pathway by the protein kinase raf

  Howe, L. R., Leevers, S. J., Gómez, N., Nakielny, S., Cohen, P. & Marshall, C. J., 16 Oct 1992, In: Cell. 71, 2, p. 335-342 8 p.

  Research output: Contribution to journal › Article › peer-review
  631 Citations (Scopus)

• Activation of the MAP kinase pathway requires p21ras and p74raf-1

  Marshall, C. J., Ashworth, A., Howe, L. R., Leevers, S. J., Paterson, H. F., Thorneycroft, S. G., Gomez, N., Nakielny, S., Traverse, S. & Cohen, P., 1 Jan 1993, In: International Journal of Cancer. 53, 1, p. 171-172 2 p.

  Research output: Contribution to journal › Article › peer-review

• Activation of the mitogen- and stress-activated kinase 1 by arsenic trioxide

  Kannan-Thulasiraman, P., Katsoulidis, E., Tallman, M. S., Arthur, J. S. C. & Platanias, L. C., 11 Aug 2006, In: Journal of Biological Chemistry. 281, 32, p. 22446-22452 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  50 Citations (Scopus)

  6 Downloads (Pure)

• Activation of the neutrophil NADPH oxidase is inhibited by SB 203580, a specific inhibitor of SAPK2/p38

  Lal, A. S., Clifton, A. D., Rouse, J., Segal, A. W. & Cohen, P., 7 Jun 1999, In: Biochemical and Biophysical Research Communications. 259, 2, p. 465-470 6 p.

  Research output: Contribution to journal › Article › peer-review
  46 Citations (Scopus)

• Activation of the novel MAP kinase homologue SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6)

  Cuenda, A., Goedert, M., Craxton, M., Jakes, R. & Cohen, P., 1 Nov 1997, In: Biochemical Society Transactions. 25, 4

  Research output: Contribution to journal › Meeting abstract › peer-review
  1 Citation (Scopus)

• Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); Comparison of its substrate specificity with that of other SAP kinases

  Goedert, M., Cuenda, A., Craxton, M., Jakes, R. & Cohen, P., 16 Jun 1997, In: EMBO Journal. 16, 12, p. 3563-3571 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  31 Citations (Scopus)

• Activation of the NRF2 Signaling Pathway by Copper-Mediated Redox Cycling of Para- and Ortho-Hydroquinones

  Wang, X. J., Hayes, J. D., Higgins, L. G., Wolf, C. R. & Dinkova-Kostova, A. T., 29 Jan 2010, In: Chemistry & Biology. 17, 1, p. 75-85 11 p.

  Research output: Contribution to journal › Article › peer-review
  87 Citations (Scopus)

• Activation of the protease from human adenovirus type 2 is accompanied by a conformational change that is dependent on cysteine-104

  Jones, S. J., Iqbal, M., Grierson, A. W. & Kemp, G., Aug 1996, In: Journal of General Virology. 77, 8, p. 1821-1824

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Activation of the Ras mitogen-activated protein kinase ribosomal protein kinase pathway is not required for the repression of phosphoenolpyruvate carboxykinase gene transcription by insulin

  Sutherland, C., Waltner-Law, M., Gnudi, L., Kahn, B. B. & Granner, D. K., 1998, In: Journal of Biological Chemistry. 273, 6, p. 3198-3204 7 p.

  Research output: Contribution to journal › Article › peer-review
  45 Citations (Scopus)

• Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process

  Castaneda-Bueno, M., Graciela Cervantes-Perez, L., Vazquez, N., Uribe, N., Kantesaria, S., Morla, L., Bobadilla, N. A., Doucet, A., Alessi, D. R. & Gamba, G., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 20, p. 7929-7934 6 p.

  Research output: Contribution to journal › Article › peer-review
  194 Citations (Scopus)

• Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

  Richardson, C., Rafiqi, F. H., Karlsson, H. K. R., Moleleki, N., Vandewalle, A., Campbell, D. G., Morrice, N. A. & Alessi, D. R., 1 Mar 2008, In: Journal of Cell Science. 121, 5, p. 675-684 10 p.

  Research output: Contribution to journal › Article › peer-review
  275 Citations (Scopus)

• Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD

  Baas, A. F., Boudeau, J., Sapkota, G. P., Smit, L., Medema, R., Morrice, N. A., Alessi, D. R. & Clevers, H. C., 2003, In: EMBO Journal. 22, 12, p. 3062-3072 11 p.

  Research output: Contribution to journal › Article › peer-review
  294 Citations (Scopus)

• Activation of transcription factor Nrf2 to counteract mitochondrial dysfunction in Parkinson’s disease

  Bento-Pereira, C. & Dinkova-Kostova, A., 25 Feb 2021, In: Medicinal Research Reviews. 41, 2, p. 785-802 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File
  29 Citations (Scopus)

  91 Downloads (Pure)

• Activation of wnt5a in epidermis triggers massive hypersensitivity to double-stranded RNA

  Reilly, L., Romanowska, M. & Foerster, J., Sept 2010, In: Journal of Investigative Dermatology. 130, S2, p. S84-S84 1 p., 500 [Oral 041].

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• Activation of μ-opioid receptors by MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine) and its fluorinated derivatives

  Baptista-Hon, D. T., Smith, M., Singleton, S., Antonides, L. H., Daeid, N. N., McKenzie, C. & Hales, T. G., 9 Jul 2020, In: British Journal of Pharmacology. 177, 15, p. 3436-3448 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  8 Citations (Scopus)

  107 Downloads (Pure)

• Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

  MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R., 1 Nov 2015, In: Cancer Research. 75, 21, p. 4573-4581 10 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes

  Cantrell, D. A., Davies, A. A. & Crumpton, M. J., 1 Dec 1985, In: Proceedings of the National Academy of Sciences of the United States of America. 82, 23, p. 8158-8162 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  219 Citations (Scopus)

• Activators of the Epstein-Barr virus lytic program concomitantly induce apoptosis, but lytic gene expression protects from cell death

  Inman, G. J., Binné, U. K., Parker, G. A., Farrell, P. J. & Allday, M. J., 2001, In: Journal of Virology. 75, 5, p. 2400-2410 11 p.

  Research output: Contribution to journal › Article › peer-review
  58 Citations (Scopus)

• Active and adaptive plasticity in a changing climate

  Brooker, R., Brown, L. K., George, T. S., Pakeman, R. J., Palmer, S., Ramsay, L., Schöb, C., Schurch, N. & Wilkinson, M. J., 1 Jul 2022, In: Trends in Plant Science. 27, 7, p. 717-728 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File
  8 Citations (Scopus)

  80 Downloads (Pure)

• Active defence responses associated with non-host resistance of Arabidopsis thaliana to the oomycete pathogen Phytophthora infestans

  Huitema, E., Vleeshouwers, V. G. A. A., Francis, D. M. & Kamoun, S., Nov 2003, In: Molecular Plant Pathology. 4, 6, p. 487-500 14 p.

  Research output: Contribution to journal › Article › peer-review
  90 Citations (Scopus)

• Active Learning for Patch-Based Digital Pathology using Convolutional Neural Networks to Reduce Annotation Costs

  Carse, J. & McKenna, S., 2019, Digital Pathology: 15th European Congress, ECDP 2019, Warwick, UK, April 10–13, 2019, Proceedings. Reyes-Aldasoro, C. C., Janowczyk, A., Veta, M., Bankhead, P. & Sirinukunwattana, K. (eds.). Switzerland: Springer , p. 20-27 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11435 LNCS).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  Open Access

  File
  8 Citations (Scopus)

  327 Downloads (Pure)

• Active learning for young people... youth participation, well-being and civic renewal

  Barber, T., 2009.

  Research output: Contribution to conference › Paper

• Active-learning methods to improve student performance and scientific interest in a large introductory oceanography course

  Yuretich, R. F., Khan, S., Leckie, R. M. & Clement, J. J., Mar 2001, In: Journal of Geoscience Education. 49, 2, p. 111-119 9 p.

  Research output: Contribution to journal › Article › peer-review
  64 Citations (Scopus)

• Active membranes: 3D printing of elastic fibre patterns on pre-stretched textiles

  Agkathidis, A., Berdos, Y. & Brown, A., 1 Mar 2019, In: International Journal of Architectural Computing. 17, 1, p. 74-87 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  9 Citations (Scopus)

  166 Downloads (Pure)

• Active microbial ecosystem in glacier basal ice fuelled by iron and silicate comminution‐derived hydrogen

  Toubes-Rodrigo, M., Potgieter-Vermaak, S., Sen, R., Oddsdóttir, E. S., Elliott, D. & Cook, S., Aug 2021, In: MicrobiologyOpen. 10, 4, 13 p., e1200.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Citation (Scopus)

  62 Downloads (Pure)

• Active momentum trading versus passive '1/N naive diversification'

  Banerjee, A. N. & Hung, C-H. D., May 2013, In: Quantitative Finance. 13, 5, p. 655-663 9 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Active MRI tracking for robotic assisted FUS

  Xiao, X., Huang, Z. & Melzer, A., 1 Mar 2017, Proceedings from the 13th International Symposium on Therapeutic Ultrasound. AIP Publishing, Vol. 1816. 080003

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  Open Access

  File
  129 Downloads (Pure)