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Protein Phosphatase 2A Is the Major Enzyme in Brain that Dephosphorylates τ Protein Phosphorylated by Proline‐Directed Protein Kinases or Cyclic AMP‐Dependent Protein Kinase
Goedert, M., Jakes, R., Qi, Z., Wang, J. H. & Cohen, P., Dec 1995, In: Journal of Neurochemistry. 65, 6, p. 2804-2807 4 p.Research output: Contribution to journal › Article › peer-review
151 Citations (Scopus) -
Protein phosphatase 2A as a therapeutic target in acute myeloid leukemia
Arriazu, E., Pippa, R. & Odero, M. D., 6 Apr 2016, In: Frontiers in Oncology. 6, APR, 78.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)203 Downloads (Pure) -
Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3
Krauss, S., Foerster, J., Schneider, R. & Schweiger, S., 15 Jun 2008, In: Cancer Research. 68, 12, p. 4658-4665 8 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
Protein phosphatase 2A and its [3H]cantharidin/[3H]endothall thioanhydride binding site: inhibitor specificity of cantharidin and ATP analogues
Li, Y-M., MacKintosh, C. & Casida, J. E., 1993, In: Biochemical Pharmacology. 46, 8, p. 1435-1443 9 p.Research output: Contribution to journal › Article › peer-review
132 Citations (Scopus) -
Protein phosphatase 2A1 is the major enzyme in vertebrate cell extracts that dephosphorylates several physiological substrates for cyclin-dependent protein kinases
Ferrigno, P., Langan, T. A. & Cohen, P., 1 Jul 1993, In: Molecular Biology of the Cell. 4, 7, p. 669-677 9 p.Research output: Contribution to journal › Article › peer-review
90 Citations (Scopus) -
Protein Phosphatase 2A (PP2A)-specific Ubiquitin Ligase MID1 Is a Sequence-dependent Regulator of Translation Efficiency Controlling 3-Phosphoinositide-dependent Protein Kinase-1 (PDPK-1)
Aranda-Orgilles, B., Rutschow, D., Zeller, R., Karagiannidis, A. I., Köhler, A., Chen, C., Wilson, T., Krause, S., Roepcke, S., Lilley, D., Schneider, R. & Schweiger, S., 18 Nov 2011, In: Journal of Biological Chemistry. 286, 46, p. 39945-39957 13 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Protein phosphatase 1c associated with the cardiac sodium calcium exchanger1 regulates its activity by dephosphorylating serine 68 phosphorylated phospholemman
Lubelwana Hafver, T., Hodne, K., Wanichawan, P., Aronsen, J. M., Dalhus, B., Lunde, P. K., Lunde, M., Martinsen, M., Enger, U. H., Fuller, W., Sjaastad, I., Louch, W. E., Sejersted, O. M. & Carlson, C. R., 26 Feb 2016, In: Journal of Biological Chemistry. 291, 9, p. 4561-4579 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)252 Downloads (Pure) -
Protein phosphatase 1 can modulate alternative 5′ splice site selection in a HeLa splicing extract
Cardinali, B., Cohen, P. T. W. & Lamond, A. I., 3 Oct 1994, In: FEBS Letters. 352, 3, p. 276-280 5 p.Research output: Contribution to journal › Article › peer-review
45 Citations (Scopus) -
Protein Phosphatase-1 and Protein Phosphatase-2A from Rabbit Skeletal Muscle
Cohen, P., Alemany, S., Therese, B. A., Resink, T. J., Stralfors, P. & Lim Tung, H. Y., 1988, In: Methods in Enzymology. 159, C, p. 390-408 19 p.Research output: Contribution to journal › Article › peer-review
387 Citations (Scopus) -
Protein O-GlcNAcylation is required for fibroblast growth factor signaling in Drosophila
Mariappa, D., Sauert, K., Marino, K., Turnock, D., Webster, R., van Aalten, D. M. F., Ferguson, M. A. J. & Muller, H. A. J., 20 Dec 2011, In: Science Signaling. 4, 204, p. - 8 p., ra89.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Protein multiple sequence alignment and flexible pattern matching
Barton, G. J., 1990, In: Methods in Enzymology. 183, p. 403-28 26 p.Research output: Contribution to journal › Article
180 Citations (Scopus) -
Protein mislocalization in plant cells using a GFP-binding chromobody
Schornack, S., Fuchs, R., Huitema, E., Rothbauer, U., Lipka, V. & Kamoun, S., Nov 2009, In: Plant Journal. 60, 4, p. 744-754 11 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
Protein-Metal Interactions of Calmodulin and alpha-Synuclein Monitored by Selective Noncovalent Adduct Protein Probing Mass Spectrometry
Ly, T. & Julian, R. R., Nov 2008, In: Journal of The American Society for Mass Spectrometry. 19, 11, p. 1663-1672 10 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
Protein localization and dynamics within a bacterial organelle
Hughes, H. V., Huitema, E., Pritchard, S., Keiler, K. C., Brun, Y. V. & Viollier, P. H., 23 Mar 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 12, p. 5599-5604 6 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate
Scott, J. W., Norman, D. G., Hawley, S. A., Kontogiannis, L. & Hardie, D. G., 22 Mar 2002, In: Journal of Molecular Biology. 317, 2, p. 309-323 15 p.Research output: Contribution to journal › Article › peer-review
139 Citations (Scopus) -
Protein kinases - The major drug targets of the twenty-first century?
Cohen, P., 1 Apr 2002, In: Nature Reviews Drug Discovery. 1, 4, p. 309-315 7 p.Research output: Contribution to journal › Article › peer-review
1843 Citations (Scopus) -
Protein Kinases of the Innate Immune System as Drug Targets
Cohen, P., Aug 2009, In: Journal of Biomolecular Screening. 14, 7, p. 894-894 1 p.Research output: Contribution to journal › Book/Film/Article review › peer-review
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Protein Kinases in Pluripotency - Beyond the Usual Suspects
Fernandez-Alonso, R., Bustos, F., Williams, C. A. C. & Findlay, G. M., 19 May 2017, In: Journal of Molecular Biology. 429, 10, p. 1504-1520 17 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile9 Citations (Scopus)173 Downloads (Pure) -
Protein kinases, from B to C
Cameron, A. J., De Rycker, M., Calleja, V., Alcor, D., Kjaer, S., Kostelecky, B., Saurin, A., Faisal, A., Laguerre, M., Hemmings, B. A., McDonald, N., Larijani, B. & Parker, P. J., 1 Nov 2007, In: Biochemical Society Transactions. 35, 5, p. 1013-1017 5 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
Protein kinase networks that limit TLR signalling
Clark, K., 1 Feb 2014, In: Biochemical Society Transactions. 42, 1, p. 11-24 14 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
Protein kinase inhibitors for the treatment of disease: The promise and the problems
Cohen, P., 1 Dec 2005, Inhibitors of Protein Kinases and Protein Phosphates. p. 1-7 7 p. (Handbook of Experimental Pharmacology; vol. 167).Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Citations (Scopus) -
Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells
Lopez Pelaez, M., Lamont, D. J., Peggie, M., Shpiro, N., Gray, N. S. & Cohen, P., 9 Dec 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 49, p. 17432-17437 6 p.Research output: Contribution to journal › Article › peer-review
79 Citations (Scopus) -
Protein kinase FA/glycogen synthase kinase 3 alpha predominantly phosphorylates the in vivo sites of Ser502, Ser506, Ser603, and Ser666 in neurofilament
Yang, S. D., Huang, J-J. & Huang, T-J., Apr 1995, In: Journal of Neurochemistry. 64, 4, p. 1848-54 7 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues
Matthews, S. A., Lek, H. S., Morrison, V. L., Mackenzie, M. G., Zarrouk, M., Cantrell, D. & Fagerholm, S. C., May 2012, In: European Journal of Immunology. 42, 5, p. 1316-1326 11 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus) -
Protein kinase D is a downstream target of protein kinase Cθ1
Yuan, J., Bae, D., Cantrell, D., Nel, A. E. & Rozengurt, E., 1 Mar 2002, In: Biochemical and Biophysical Research Communications. 291, 3, p. 444-452 9 p.Research output: Contribution to journal › Article › peer-review
61 Citations (Scopus) -
Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFκB activity in vertebrate B-cells
Liu, P., Scharenberg, A. M., Cantrell, D. A., Matthews, S. A. & Marais, R. (ed.), 2007, In: FEBS Letters. 581, 7, p. 1377-1382 6 p.Research output: Contribution to journal › Article › peer-review
File21 Citations (Scopus)306 Downloads (Pure) -
Protein kinase D2 is a digital amplifier of T cell receptor-stimulated diacylglycerol signaling in naïve CD8+ T cells
Navarro, M. N., Feijoo-Carnero, C., Gonzalez Arandilla, A., Trost, M. & Cantrell, D. A., 21 Oct 2014, In: Science Signaling. 7, 348, 12 p., ra99.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells
Navarro, M. N., Sinclair, L. V., Feijoo-Carnero, C., Clarke, R., Matthews, S. A. & Cantrell, D. A., 15 Mar 2012, In: Biochemical Journal. 442, 3, p. 649-659 11 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Protein kinase D : A selective target for antigen receptors and a downstream target for protein kinase C in lymphocytes
Matthews, S. A., Rozengurt, E. & Cantrell, D., 2000, In: Journal of Experimental Medicine. 191, 12, p. 2075-82 8 p.Research output: Contribution to journal › Article › peer-review
98 Citations (Scopus) -
Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2
Konopatskaya, O., Matthews, S. A., Harper, M. T., Gilio, K., Cosemans, J. M. E. M., Williams, C. M., Navarro, M. N., Carter, D. A., Heemskerk, J. W. M., Leitges, M., Cantrell, D. & Poole, A. W., 14 Jul 2011, In: Blood. 118, 2, p. 416-424 9 p.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
Protein Kinase C-mediated Phosphorylation and activation of PDE3A Regulate cAMP levels in human platelets
Hunter, R., MacKintosh, C. & Hers, I., 2009, In: Journal of Biological Chemistry. 284, 18, p. 12339-12348 10 p.Research output: Contribution to journal › Article › peer-review
69 Citations (Scopus) -
Protein kinase CK2-dependent regulation of p53 function: evidence that the phosphorylation status of the serine 386 (CK2) site of p53 is constitutive and stable
McKendrick, L., Milne, D. & Meek, D., Jan 1999, In: Molecular and Cellular Biochemistry. 191, 1-2, p. 187-199 13 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the deltaF508 mutation: F508 deletion disrupts a kinase-binding site
Treharne, K. J., Crawford, R. M., Xu, Z., Chen, J-H., Best, O. G., Schulte, E. A., Gruenert, D. C., Wilson, S. M., Sheppard, D. N., Kunzelmann, K. & Mehta, A., 2007, In: Journal of Biological Chemistry. 282, 14, p. 10804-10813 10 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Protein kinase CK1δ phosphorylates key sites in the acidic domain of murine double-minute clone 2 protein (MDM2) that regulate p53 turnover
Winter, M., Milne, D., Dias, S., Kulikov, R., Knippschild, U., Blattner, C. & Meek, D., Dec 2004, In: Biochemistry. 43, 51, p. 16356-16364 9 p.Research output: Contribution to journal › Article › peer-review
49 Citations (Scopus) -
Protein kinase CK1 is a p53-threonine 18 kinase which requires prior phosphorylation of serine 15
Dumaz, N., Milne, D. M. & Meek, D. W., 17 Dec 1999, In: FEBS Letters. 463, 3, p. 312-316 5 p.Research output: Contribution to journal › Article › peer-review
108 Citations (Scopus) -
Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1
Le Good, J. A., Ziegler, W. H., Parekh, D. B., Alessi, D. R., Cohen, P. & Parker, P. J., 25 Sep 1998, In: Science. 281, 5385, p. 2042-2045 4 p.Research output: Contribution to journal › Article › peer-review
972 Citations (Scopus) -
Protein kinase C is not a downstream effector of p21ras in activated T cells
Williams, D. H., Woodrow, M., Cantrell, D. A. & Murray, E. J., Jan 1995, In: European Journal of Immunology. 25, 1, p. 42-47 6 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Protein kinase C fusion proteins are paradoxically loss-of-function in cancer
Van, A-A. N., Kunkel, M. T., Baffi, T. R., Lordén, G., Antal, C. E., Banerjee, S. & Newton, A. C., 2021, In: Journal of Biological Chemistry. 296, p. 1-18 18 p., 100445.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)88 Downloads (Pure) -
Protein kinase C epsilon in cell division Control of abscission
Saurin, A. T., Brownlow, N. & Parker, P. J., 2009, In: Cell Cycle. 8, 4, p. 549-555 7 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Protein kinase C and beyond
Spitaler, M. & Cantrell, D. A., Aug 2004, In: Nature Immunology. 5, 8, p. 785-790 6 p.Research output: Contribution to journal › Review article › peer-review
244 Citations (Scopus) -
Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism
Macintyre, A. N., Finlay, D., Preston, G., Sinclair, L. V., Waugh, C. M., Tamas, P., Feijoo, C., Okkenhaug, K. & Cantrell, D. A., 25 Feb 2011, In: Immunity. 34, 2, p. 224-236 13 p.Research output: Contribution to journal › Article › peer-review
File202 Citations (Scopus)262 Downloads (Pure) -
Protein kinase B (PKB/Akt) - A key regulator of glucose transport?
Hajduch, E., Litherland, G. J. & Hundal, H. S., 16 Mar 2001, In: FEBS Letters. 492, 3, p. 199-203 5 p.Research output: Contribution to journal › Short survey › peer-review
234 Citations (Scopus) -
Protein kinase B (Akt) regulation and function in T lymphocytes
Cantrell, D., Feb 2002, In: Seminars in Immunology. 14, 1, p. 19-26 8 p.Research output: Contribution to journal › Article › peer-review
105 Citations (Scopus) -
Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c
Martin, M. C., Allan, L. A., Lickrish, M., Sampson, C., Morrice, N. & Clarke, P. R., 15 Apr 2005, In: Journal of Biological Chemistry. 280, 15, p. 15449-15455 7 p.Research output: Contribution to journal › Article › peer-review
86 Citations (Scopus) -
Protein interactions within Saccharomyces cerevisiae Elongator, a complex essential for Kluyveromyces lactis zymocicity
Fichtner, L., Frohloff, F., Jablonowski, D., Stark, M. J. R. & Schaffrath, R., Aug 2002, In: Molecular Microbiology. 45, 3, p. 817-26 10 p.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus) -
Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila
McGurk, L. & Bonini, N. M., 1 Jan 2012, In: Human Molecular Genetics. 21, 1, p. 76-84 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)50 Downloads (Pure) -
Protein histidine phosphatase activity in rat liver and spinach leaves
Matthews, H. R. & MacKintosh, C., 1995, In: FEBS Letters. 364, 1, p. 51-54 4 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Protein fold recognition from secondary structure assignments
Russell, R. B., Copley, R. R. & Barton, G. J., 1995, Proceedings of the 28th Annual Hawaii International Conference on System Sciences (HICSS 1995). IEEE, p. 302-311 10 p. 375326. (Proceedings of the Annual Hawaii International Conference on System Sciences; vol. 5).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
10 Citations (Scopus) -
Protein fold recognition by mapping predicted secondary structures
Russell, R. B., Copley, R. R. & Barton, G. J., 14 Jun 1996, In: Journal of Molecular Biology. 259, 3, p. 349-365 17 p.Research output: Contribution to journal › Article › peer-review
116 Citations (Scopus) -
Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liver
Kitteringham, N. R., Powell, H., Hamlett, J., Hamlett, J., Lovatt, C., Elsby, R., Henderson, C. J., Wolf, C. R., Pennington, S. R. & Park, B. K., Feb 2003, In: Proteomics. 3, 2, p. 191-207 17 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus)