Find Research outputs

Search results

• Protein Phosphatase 2A Is the Major Enzyme in Brain that Dephosphorylates τ Protein Phosphorylated by Proline‐Directed Protein Kinases or Cyclic AMP‐Dependent Protein Kinase

  Goedert, M., Jakes, R., Qi, Z., Wang, J. H. & Cohen, P., Dec 1995, In: Journal of Neurochemistry. 65, 6, p. 2804-2807 4 p.

  Research output: Contribution to journal › Article › peer-review
  151 Citations (Scopus)

• Protein phosphatase 2A as a therapeutic target in acute myeloid leukemia

  Arriazu, E., Pippa, R. & Odero, M. D., 6 Apr 2016, In: Frontiers in Oncology. 6, APR, 78.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  34 Citations (Scopus)

  203 Downloads (Pure)

• Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3

  Krauss, S., Foerster, J., Schneider, R. & Schweiger, S., 15 Jun 2008, In: Cancer Research. 68, 12, p. 4658-4665 8 p.

  Research output: Contribution to journal › Article › peer-review
  44 Citations (Scopus)

• Protein phosphatase 2A and its [3H]cantharidin/[3H]endothall thioanhydride binding site: inhibitor specificity of cantharidin and ATP analogues

  Li, Y-M., MacKintosh, C. & Casida, J. E., 1993, In: Biochemical Pharmacology. 46, 8, p. 1435-1443 9 p.

  Research output: Contribution to journal › Article › peer-review
  132 Citations (Scopus)

• Protein phosphatase 2A₁ is the major enzyme in vertebrate cell extracts that dephosphorylates several physiological substrates for cyclin-dependent protein kinases

  Ferrigno, P., Langan, T. A. & Cohen, P., 1 Jul 1993, In: Molecular Biology of the Cell. 4, 7, p. 669-677 9 p.

  Research output: Contribution to journal › Article › peer-review
  90 Citations (Scopus)

• Protein Phosphatase 2A (PP2A)-specific Ubiquitin Ligase MID1 Is a Sequence-dependent Regulator of Translation Efficiency Controlling 3-Phosphoinositide-dependent Protein Kinase-1 (PDPK-1)

  Aranda-Orgilles, B., Rutschow, D., Zeller, R., Karagiannidis, A. I., Köhler, A., Chen, C., Wilson, T., Krause, S., Roepcke, S., Lilley, D., Schneider, R. & Schweiger, S., 18 Nov 2011, In: Journal of Biological Chemistry. 286, 46, p. 39945-39957 13 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Protein phosphatase 1c associated with the cardiac sodium calcium exchanger1 regulates its activity by dephosphorylating serine 68 phosphorylated phospholemman

  Lubelwana Hafver, T., Hodne, K., Wanichawan, P., Aronsen, J. M., Dalhus, B., Lunde, P. K., Lunde, M., Martinsen, M., Enger, U. H., Fuller, W., Sjaastad, I., Louch, W. E., Sejersted, O. M. & Carlson, C. R., 26 Feb 2016, In: Journal of Biological Chemistry. 291, 9, p. 4561-4579 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  11 Citations (Scopus)

  252 Downloads (Pure)

• Protein phosphatase 1 can modulate alternative 5′ splice site selection in a HeLa splicing extract

  Cardinali, B., Cohen, P. T. W. & Lamond, A. I., 3 Oct 1994, In: FEBS Letters. 352, 3, p. 276-280 5 p.

  Research output: Contribution to journal › Article › peer-review
  45 Citations (Scopus)

• Protein Phosphatase-1 and Protein Phosphatase-2A from Rabbit Skeletal Muscle

  Cohen, P., Alemany, S., Therese, B. A., Resink, T. J., Stralfors, P. & Lim Tung, H. Y., 1988, In: Methods in Enzymology. 159, C, p. 390-408 19 p.

  Research output: Contribution to journal › Article › peer-review
  387 Citations (Scopus)

• Protein O-GlcNAcylation is required for fibroblast growth factor signaling in Drosophila

  Mariappa, D., Sauert, K., Marino, K., Turnock, D., Webster, R., van Aalten, D. M. F., Ferguson, M. A. J. & Muller, H. A. J., 20 Dec 2011, In: Science Signaling. 4, 204, p. - 8 p., ra89.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Protein multiple sequence alignment and flexible pattern matching

  Barton, G. J., 1990, In: Methods in Enzymology. 183, p. 403-28 26 p.

  Research output: Contribution to journal › Article
  180 Citations (Scopus)

• Protein mislocalization in plant cells using a GFP-binding chromobody

  Schornack, S., Fuchs, R., Huitema, E., Rothbauer, U., Lipka, V. & Kamoun, S., Nov 2009, In: Plant Journal. 60, 4, p. 744-754 11 p.

  Research output: Contribution to journal › Article › peer-review
  44 Citations (Scopus)

• Protein-Metal Interactions of Calmodulin and alpha-Synuclein Monitored by Selective Noncovalent Adduct Protein Probing Mass Spectrometry

  Ly, T. & Julian, R. R., Nov 2008, In: Journal of The American Society for Mass Spectrometry. 19, 11, p. 1663-1672 10 p.

  Research output: Contribution to journal › Article › peer-review
  41 Citations (Scopus)

• Protein localization and dynamics within a bacterial organelle

  Hughes, H. V., Huitema, E., Pritchard, S., Keiler, K. C., Brun, Y. V. & Viollier, P. H., 23 Mar 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 12, p. 5599-5604 6 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate

  Scott, J. W., Norman, D. G., Hawley, S. A., Kontogiannis, L. & Hardie, D. G., 22 Mar 2002, In: Journal of Molecular Biology. 317, 2, p. 309-323 15 p.

  Research output: Contribution to journal › Article › peer-review
  139 Citations (Scopus)

• Protein kinases - The major drug targets of the twenty-first century?

  Cohen, P., 1 Apr 2002, In: Nature Reviews Drug Discovery. 1, 4, p. 309-315 7 p.

  Research output: Contribution to journal › Article › peer-review
  1843 Citations (Scopus)

• Protein Kinases of the Innate Immune System as Drug Targets

  Cohen, P., Aug 2009, In: Journal of Biomolecular Screening. 14, 7, p. 894-894 1 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• Protein Kinases in Pluripotency - Beyond the Usual Suspects

  Fernandez-Alonso, R., Bustos, F., Williams, C. A. C. & Findlay, G. M., 19 May 2017, In: Journal of Molecular Biology. 429, 10, p. 1504-1520 17 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File
  9 Citations (Scopus)

  173 Downloads (Pure)

• Protein kinases, from B to C

  Cameron, A. J., De Rycker, M., Calleja, V., Alcor, D., Kjaer, S., Kostelecky, B., Saurin, A., Faisal, A., Laguerre, M., Hemmings, B. A., McDonald, N., Larijani, B. & Parker, P. J., 1 Nov 2007, In: Biochemical Society Transactions. 35, 5, p. 1013-1017 5 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• Protein kinase networks that limit TLR signalling

  Clark, K., 1 Feb 2014, In: Biochemical Society Transactions. 42, 1, p. 11-24 14 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Protein kinase inhibitors for the treatment of disease: The promise and the problems

  Cohen, P., 1 Dec 2005, Inhibitors of Protein Kinases and Protein Phosphates. p. 1-7 7 p. (Handbook of Experimental Pharmacology; vol. 167).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  3 Citations (Scopus)

• Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells

  Lopez Pelaez, M., Lamont, D. J., Peggie, M., Shpiro, N., Gray, N. S. & Cohen, P., 9 Dec 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 49, p. 17432-17437 6 p.

  Research output: Contribution to journal › Article › peer-review
  79 Citations (Scopus)

• Protein kinase FA/glycogen synthase kinase 3 alpha predominantly phosphorylates the in vivo sites of Ser502, Ser506, Ser603, and Ser666 in neurofilament

  Yang, S. D., Huang, J-J. & Huang, T-J., Apr 1995, In: Journal of Neurochemistry. 64, 4, p. 1848-54 7 p.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues

  Matthews, S. A., Lek, H. S., Morrison, V. L., Mackenzie, M. G., Zarrouk, M., Cantrell, D. & Fagerholm, S. C., May 2012, In: European Journal of Immunology. 42, 5, p. 1316-1326 11 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Protein kinase D is a downstream target of protein kinase Cθ¹

  Yuan, J., Bae, D., Cantrell, D., Nel, A. E. & Rozengurt, E., 1 Mar 2002, In: Biochemical and Biophysical Research Communications. 291, 3, p. 444-452 9 p.

  Research output: Contribution to journal › Article › peer-review
  61 Citations (Scopus)

• Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFκB activity in vertebrate B-cells

  Liu, P., Scharenberg, A. M., Cantrell, D. A., Matthews, S. A. & Marais, R. (ed.), 2007, In: FEBS Letters. 581, 7, p. 1377-1382 6 p.

  Research output: Contribution to journal › Article › peer-review

  File
  21 Citations (Scopus)

  306 Downloads (Pure)

• Protein kinase D2 is a digital amplifier of T cell receptor-stimulated diacylglycerol signaling in naïve CD8⁺ T cells

  Navarro, M. N., Feijoo-Carnero, C., Gonzalez Arandilla, A., Trost, M. & Cantrell, D. A., 21 Oct 2014, In: Science Signaling. 7, 348, 12 p., ra99.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells

  Navarro, M. N., Sinclair, L. V., Feijoo-Carnero, C., Clarke, R., Matthews, S. A. & Cantrell, D. A., 15 Mar 2012, In: Biochemical Journal. 442, 3, p. 649-659 11 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Protein kinase D : A selective target for antigen receptors and a downstream target for protein kinase C in lymphocytes

  Matthews, S. A., Rozengurt, E. & Cantrell, D., 2000, In: Journal of Experimental Medicine. 191, 12, p. 2075-82 8 p.

  Research output: Contribution to journal › Article › peer-review
  98 Citations (Scopus)

• Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2

  Konopatskaya, O., Matthews, S. A., Harper, M. T., Gilio, K., Cosemans, J. M. E. M., Williams, C. M., Navarro, M. N., Carter, D. A., Heemskerk, J. W. M., Leitges, M., Cantrell, D. & Poole, A. W., 14 Jul 2011, In: Blood. 118, 2, p. 416-424 9 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Protein Kinase C-mediated Phosphorylation and activation of PDE3A Regulate cAMP levels in human platelets

  Hunter, R., MacKintosh, C. & Hers, I., 2009, In: Journal of Biological Chemistry. 284, 18, p. 12339-12348 10 p.

  Research output: Contribution to journal › Article › peer-review
  69 Citations (Scopus)

• Protein kinase CK2-dependent regulation of p53 function: evidence that the phosphorylation status of the serine 386 (CK2) site of p53 is constitutive and stable

  McKendrick, L., Milne, D. & Meek, D., Jan 1999, In: Molecular and Cellular Biochemistry. 191, 1-2, p. 187-199 13 p.

  Research output: Contribution to journal › Article › peer-review
  42 Citations (Scopus)

• Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the deltaF508 mutation: F508 deletion disrupts a kinase-binding site

  Treharne, K. J., Crawford, R. M., Xu, Z., Chen, J-H., Best, O. G., Schulte, E. A., Gruenert, D. C., Wilson, S. M., Sheppard, D. N., Kunzelmann, K. & Mehta, A., 2007, In: Journal of Biological Chemistry. 282, 14, p. 10804-10813 10 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Protein kinase CK1δ phosphorylates key sites in the acidic domain of murine double-minute clone 2 protein (MDM2) that regulate p53 turnover

  Winter, M., Milne, D., Dias, S., Kulikov, R., Knippschild, U., Blattner, C. & Meek, D., Dec 2004, In: Biochemistry. 43, 51, p. 16356-16364 9 p.

  Research output: Contribution to journal › Article › peer-review
  49 Citations (Scopus)

• Protein kinase CK1 is a p53-threonine 18 kinase which requires prior phosphorylation of serine 15

  Dumaz, N., Milne, D. M. & Meek, D. W., 17 Dec 1999, In: FEBS Letters. 463, 3, p. 312-316 5 p.

  Research output: Contribution to journal › Article › peer-review
  108 Citations (Scopus)

• Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

  Le Good, J. A., Ziegler, W. H., Parekh, D. B., Alessi, D. R., Cohen, P. & Parker, P. J., 25 Sep 1998, In: Science. 281, 5385, p. 2042-2045 4 p.

  Research output: Contribution to journal › Article › peer-review
  972 Citations (Scopus)

• Protein kinase C is not a downstream effector of p21^ras in activated T cells

  Williams, D. H., Woodrow, M., Cantrell, D. A. & Murray, E. J., Jan 1995, In: European Journal of Immunology. 25, 1, p. 42-47 6 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Protein kinase C fusion proteins are paradoxically loss-of-function in cancer

  Van, A-A. N., Kunkel, M. T., Baffi, T. R., Lordén, G., Antal, C. E., Banerjee, S. & Newton, A. C., 2021, In: Journal of Biological Chemistry. 296, p. 1-18 18 p., 100445.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  10 Citations (Scopus)

  88 Downloads (Pure)

• Protein kinase C epsilon in cell division Control of abscission

  Saurin, A. T., Brownlow, N. & Parker, P. J., 2009, In: Cell Cycle. 8, 4, p. 549-555 7 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Protein kinase C and beyond

  Spitaler, M. & Cantrell, D. A., Aug 2004, In: Nature Immunology. 5, 8, p. 785-790 6 p.

  Research output: Contribution to journal › Review article › peer-review
  244 Citations (Scopus)

• Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism

  Macintyre, A. N., Finlay, D., Preston, G., Sinclair, L. V., Waugh, C. M., Tamas, P., Feijoo, C., Okkenhaug, K. & Cantrell, D. A., 25 Feb 2011, In: Immunity. 34, 2, p. 224-236 13 p.

  Research output: Contribution to journal › Article › peer-review

  File
  202 Citations (Scopus)

  262 Downloads (Pure)

• Protein kinase B (PKB/Akt) - A key regulator of glucose transport?

  Hajduch, E., Litherland, G. J. & Hundal, H. S., 16 Mar 2001, In: FEBS Letters. 492, 3, p. 199-203 5 p.

  Research output: Contribution to journal › Short survey › peer-review
  234 Citations (Scopus)

• Protein kinase B (Akt) regulation and function in T lymphocytes

  Cantrell, D., Feb 2002, In: Seminars in Immunology. 14, 1, p. 19-26 8 p.

  Research output: Contribution to journal › Article › peer-review
  105 Citations (Scopus)

• Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c

  Martin, M. C., Allan, L. A., Lickrish, M., Sampson, C., Morrice, N. & Clarke, P. R., 15 Apr 2005, In: Journal of Biological Chemistry. 280, 15, p. 15449-15455 7 p.

  Research output: Contribution to journal › Article › peer-review
  86 Citations (Scopus)

• Protein interactions within Saccharomyces cerevisiae Elongator, a complex essential for Kluyveromyces lactis zymocicity

  Fichtner, L., Frohloff, F., Jablonowski, D., Stark, M. J. R. & Schaffrath, R., Aug 2002, In: Molecular Microbiology. 45, 3, p. 817-26 10 p.

  Research output: Contribution to journal › Article › peer-review
  36 Citations (Scopus)

• Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila

  McGurk, L. & Bonini, N. M., 1 Jan 2012, In: Human Molecular Genetics. 21, 1, p. 76-84 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  18 Citations (Scopus)

  50 Downloads (Pure)

• Protein histidine phosphatase activity in rat liver and spinach leaves

  Matthews, H. R. & MacKintosh, C., 1995, In: FEBS Letters. 364, 1, p. 51-54 4 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Protein fold recognition from secondary structure assignments

  Russell, R. B., Copley, R. R. & Barton, G. J., 1995, Proceedings of the 28th Annual Hawaii International Conference on System Sciences (HICSS 1995). IEEE, p. 302-311 10 p. 375326. (Proceedings of the Annual Hawaii International Conference on System Sciences; vol. 5).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  10 Citations (Scopus)

• Protein fold recognition by mapping predicted secondary structures

  Russell, R. B., Copley, R. R. & Barton, G. J., 14 Jun 1996, In: Journal of Molecular Biology. 259, 3, p. 349-365 17 p.

  Research output: Contribution to journal › Article › peer-review
  116 Citations (Scopus)

• Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liver

  Kitteringham, N. R., Powell, H., Hamlett, J., Hamlett, J., Lovatt, C., Elsby, R., Henderson, C. J., Wolf, C. R., Pennington, S. R. & Park, B. K., Feb 2003, In: Proteomics. 3, 2, p. 191-207 17 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)