Find Research outputs

Pharmacological treatment and perceived health status during 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization: results from the Euro Heart Survey on Coronary Revascularization

Lenzen, M., Scholte op Reimer, W., Norekval, T. M., De Geest, S., Fridlund, B., Heikkila, J., Jaarsma, T., Martensson, J., Moons, P., Smith, K., Stewart, S., Stromberg, A., Thompson, D. R. & Wijns, W., Jun 2006, In: European Journal of Cardiovascular Nursing. 5, 2, p. 115-121 7 p.

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Pharmacological space

Hopkins, A. L., 2008, The practice of medicinal chemistry. Wermuth, C. G. (ed.). 3rd ed. London: Academic Press, p. 521-532 12 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Citations (Scopus)

Pharmacological space

Hopkins, A. L., 2015, The practice of medicinal chemistry. Wermuth, C., Aldous, D., Raboisson, P. & Rognan, D. (eds.). 4th ed. Academic Press, p. 395-408 14 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease

Salter, M., Biggadike, K., Matthews, J. L., West, M. R., Haase, M. V., Farrow, S. N., Uings, I. J. & Gray, D. W., 2007, In: American Journal of Physiology: Lung Cellular and Molecular Physiology. 293, 3, p. L660-7 8 p.

Research output: Contribution to journal › Article › peer-review

132 Citations (Scopus)

Pharmacological profiling of the Dictyostelium adenylate cyclases ACA, ACB and ACG

Alvarez-Curto, E., Weening, K. E. & Schaap, P., 1 Jan 2007, In: Biochemical Journal. 401, 1, p. 309-16 8 p.

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Pharmacological management of neuropathic pain in non-specialist settings: summary of NICE guidance

Tan, T., Barry, P., Reken, S., Baker, M. & Smith, B., 2010, In: British Medical Journal. 340, p. c1079

Research output: Contribution to journal › Article › peer-review

87 Citations (Scopus)

Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy

Petherick, K. J., Conway, O. J. L., Mpamhanga, C., Osborne, S. A., Kamal, A., Saxty, B. & Ganley, I. G., 1 May 2015, In: Journal of Biological Chemistry. 290, 18, p. 11376-11383 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

134 Citations (Scopus)

4 Downloads (Pure)

Pharmacological inhibition of ATM by KU55933 stimulates ATM transcription

Khalil, H. S., Tummala, H., Hupp, T. R. & Zhelev, N., 1 Jun 2012, In: Experimental Biology and Medicine. 237, 6, p. 622-634 13 p.

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Pharmacological disruption of the MID1/α4 interaction reduces mutant Huntingtin levels in primary neuronal cultures

Monteiro, O., Chen, C., Bingham, R., Argyrou, A., Buxton, R., Jönsson, C. P., Jones, E., Bridges, A., Gatfield, K., Krauß, S., Lambert, J., Langston, R., Schweiger, S. & Uings, I., 23 Apr 2018, In: Neuroscience Letters. 673, p. 44-50 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2 Citations (Scopus)

329 Downloads (Pure)

Pharmacological characterization of the apparent splice variants of the murine 5-HT₃ R-A subunit expressed in Xenopus laevis oocytes

Downie, D. L., Hope, A. G., Lambert, J. J., Peters, J. A., Blackburn, T. P. & Jones, B. J., Mar 1994, In: Neuropharmacology. 33, 3-4, p. 473-482 10 p.

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Pharmacological characterization of a rat 5-hydroxytryptamine type₃ receptor subunit (r5-HT(3A(b)) expressed in Xenopus laevis oocytes

Mair, I. D., Lambert, J. J., Yang, J., Dempster, J. & Peters, J. A., Aug 1998, In: British Journal of Pharmacology. 124, 8, p. 1667-1674 8 p.

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Pharmacological characterization of a novel cell line expressing human α 4β 3δ GABA A receptors: Commentary on Brown et al

Lambert, J. J. & Belelli, D., Aug 2002, In: British Journal of Pharmacology. 136, 7, p. 957-959 3 p.

Research output: Contribution to journal › Comment/debate › peer-review

4 Citations (Scopus)

Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers

Lopez-Charcas, O., Pukkanasut, P., Velu, S. E., Brackenbury, W. J., Hales, T. G., Besson, P., Gomora, J. C. & Roger, S., 23 Apr 2021, In: iScience. 24, 4, p. 102270 26 p., 102270.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

10 Downloads (Pure)

Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past to Help Discover Long-Acting Oral Drugs in the Future

Smith, P. W., Zuccotto, F., Bates, R. H., Martinez-Martinez, M. S., Read, K. D., Peet, C. & Epemolu, O., 12 Oct 2018, In: ACS Infectious Diseases. 4, 10, p. 1439-1447 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

9 Citations (Scopus)

162 Downloads (Pure)

Pharmacokinetics of metformin in patients with gastrointestinal intolerance

McCreight, L., Stage, T. B., Connelly, P., Lonergan, M., Nielsen, F., Prehn, C., Adamski, J., Brosen, K. & Pearson, E. R., 1 Jul 2018, In: Diabetes, Obesity & Metabolism. 20, 7, p. 1593-1601 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

17 Citations (Scopus)

160 Downloads (Pure)

Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

Kostov, R. V., Knatko, E. V., McLaughlin, L. A., Henderson, C. J., Zheng, S., Huang, J. T. J., Honda, T. & Dinkova-Kostova, A. T., 25 Sep 2015, In: Biochemical and Biophysical Research Communications. 465, 3, p. 402-407 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

12 Citations (Scopus)

130 Downloads (Pure)

Pharmacokinetics, Metabolism, Biodistribution, Radiation Dosimetry, and Toxicology of F-18-Fluoroacetate (F-18-FACE) in Non-human Primates

Nishii, R., Tong, W., Wendt, R., Soghomonyan, S., Mukhopadhyay, U., Balatoni, J., Mawlawi, O., Bidaut, L., Tinkey, P., Borne, A., Alauddin, M., Gonzalez-Lepera, C., Yang, B. & Gelovani, J. G., Apr 2012, In: Molecular Imaging and Biology. 14, 2, p. 213-224 12 p.

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Pharmacokinetics, efficacy and adverse effects of sublingual salbutamol in patients with asthma

Lipworth, B. J., Clark, R. A., Dhillon, D. P., Moreland, T. A., Struthers, A. D., Clark, G. A. & McDevitt, D. G., 1989, In: European Journal of Clinical Pharmacology. 37, 6, p. 567-571 5 p.

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Pharmacokinetic interaction of the antiparasitic agents ivermectin and spinosad in dogs

Dunn, S. T., Hedges, L., Sampson, K. E., Lai, Y., Mahabir, S., Balogh, L. & Locuson, C. W., 1 May 2011, In: Drug Metabolism and Disposition. 39, 5, p. 789-795 7 p.

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide

Clearie, K. L., Williamson, P. A., Meldrum, K., Gillen, M., Carlsson, L-G., Carlholm, M., Ekelund, J. & Lipworth, B. J., Apr 2011, In: British Journal of Clinical Pharmacology. 71, 4, p. 504-513 10 p.

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

PREDICTION-ADR Consortium, EUDRAGENE, Floyd, J. S., Bloch, K. M., Brody, J. A., Maroteau, C., Siddiqui, M. K., Gregory, R., Carr, D. F., Molokhia, M., Liu, X., Bis, J. C., Ahmed, A., Liu, X., Hallberg, P., Yue, Q., Magnusson, P. K. E., Brisson, D., Wiggins, K. L., Morrison, A. C. & 23 others, Khoury, E., McKeigue, P., Stricker, B. H., Lapeyre-Mestre, M., Heckbert, S. R., Gallagher, A. M., Chinoy, H., Gibbs, R. A., Bondon-Guitton, E., Tracy, R., Boerwinkle, E., Gaudet, D., Conforti, A., Van Staa, T., Sitlani, C. M., Rice, K. M., Maitland-van der Zee, A., Wadelius, M., Morris, A. P., Pirmohamed, M., Palmer, C. N. A., Psaty, B. M. & Alfirevic, A., 26 Jun 2019, In: PLoS ONE. 14, 6, p. 1-13 13 p., e0218115.

Research output: Contribution to journal › Article › peer-review

Open Access

File

8 Citations (Scopus)

73 Downloads (Pure)

Pharmacogenomics in diabetes mellitus: insights into drug action and drug discovery

Zhou, K., Pedersen, H. K., Dawed, A. Y. & Pearson, E. R., Jun 2016, In: Nature Reviews Endocrinology. 12, 6, p. 337-346 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

34 Citations (Scopus)

259 Downloads (Pure)

Pharmacogenetics testing: implications for cardiovascular therapeutics with clopidogrel and warfarin

George, J., Doney, A., Palmer, C. N. & Lang, C. C., 2010, In: Cardiovascular Therapeutics. 28, 3, p. 135-138 4 p.

Research output: Contribution to journal › Editorial › peer-review

4 Citations (Scopus)

Pharmacogenetics of sulfonylureas

Kovacs, P. & Pearson, E., 12 Apr 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Florez, J. C. (ed.). Springer International Publishing, p. 483-497 15 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Citation (Scopus)

Pharmacogenetics of oral antidiabetic drugs

Becker, M. L., Pearson, E. R. & Tkáč, I., 2013, In: International Journal of Endocrinology. 2013, 10 p., 686315.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

31 Citations (Scopus)

99 Downloads (Pure)

Pharmacogenetics of metformin

Yee, S. W., Zhou, K. & Giacomini, K. M., 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Florez, J. C. (ed.). Springer International Publishing, p. 463-481 19 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Pharmacogenetics of inhaled long-acting beta2-agonists in asthma: a systematic review

Slob, E. M. A., Vijverberg, S. J. H., Palmer, C. N. A., Zazuli, Z., Farzan, N., Oliveri, N. M. B., Pijnenburg, M. W., Koppelman, G. H. & Maitland van der Zee, A. H., Nov 2018, In: Pediatric Allergy and Immunology. 29, 7, p. 705-714 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

13 Citations (Scopus)

230 Downloads (Pure)

Pharmacogenetics in type 2 diabetes: Influence on response to oral hypoglycemic agents

Dawed, A. Y., Zhou, K. & Pearson, E. R., 6 Apr 2016, In: Pharmacogenomics and Personalized Medicine. 9, p. 17-29 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

17 Citations (Scopus)

176 Downloads (Pure)

Pharmacogenetics in diabetes

Pearson, E. R., Apr 2009, In: Current Diabetes Reports. 9, 2, p. 172-181 10 p.

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Pharmacogenetics and target identification in diabetes

Pearson, E. R., 1 Jun 2018, In: Current Opinion in Genetics & Development. 50, p. 68-73 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

File

6 Citations (Scopus)

250 Downloads (Pure)

Pharmacogenetics and future strategies in treating hyperglycaemia in diabetes

Pearson, E. R., Jan 2009, In: Frontiers in Bioscience. 14, p. 4348-4362 15 p.

Research output: Contribution to journal › Review article › peer-review

21 Citations (Scopus)

Pharmacogenetics

Wolf, C. R., Smith, G. & Smith, R. L., 2000, In: British Medical Journal. 320, 7240, p. 987-90 4 p.

Research output: Contribution to journal › Article › peer-review

215 Citations (Scopus)

Pharmacogenetics

Wolf, C. R. & Smith, G., 1999, In: British Medical Bulletin. 55, 2, p. 366-86 21 p.

Research output: Contribution to journal › Article › peer-review

94 Citations (Scopus)

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

Postmus, I., Trompet, S., Deshmukh, H. A., Barnes, M. R., Li, X., Warren, H. R., Chasman, D. I., Zhou, K., Arsenault, B. J., Donnelly, L. A., Wiggins, K. L., Avery, C. L., Griffin, P., Feng, Q., Taylor, K. D., Li, G., Evans, D. S., Smith, A. V., de Keyser, C. E., Johnson, A. D. & 32 others, de Craen, A. J. M., Stott, D. J., Buckley, B. M., Ford, I., Westendorp, R. G. J., Eline Slagboom, P., Sattar, N., Munroe, P. B., Sever, P., Poulter, N., Stanton, A., Shields, D. C., O'Brien, E., Shaw-Hawkins, S., Ida Chen, Y-D., Nickerson, D. A., Smith, J. D., Pierre Dubé, M., Matthijs Boekholdt, S., Kees Hovingh, G., Kastelein, J. J. P., McKeigue, P. M., Betteridge, J., Neil, A., Durrington, P. N., Doney, A., Carr, F., Morris, A., Palmer, C. N. A., Colhoun, H. M., Jukema, J. W. & Caulfield, M. J., 28 Oct 2014, In: Nature Communications. 5, p. 1-10 10 p., 5068.

Research output: Contribution to journal › Article › peer-review

Open Access

File

144 Citations (Scopus)

196 Downloads (Pure)

Pharmacogenetic analysis of GLCCI1 in three north European pediatric asthma populations with a reported use of inhaled corticosteroids

Vijverberg, S. J. H., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., Postma, D. S., Koppelman, G. H., Turner, S. W., Mukhopadhyay, S., Palmer, C. N. A. & Maitland-Van Der Zee, A. H., Apr 2014, In: Pharmacogenomics. 15, 6, p. 799-806 8 p.

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Pharmacoepidemiological research at the Medicines Monitoring Unit, Scotland: Data protection and confidentiality

Evans, J. M. M., McNaughton, D., Donnan, P. T. & MacDonald, T. M., 1 Jan 2001, In: Pharmacoepidemiology and Drug Safety. 10, 7, p. 669-673 5 p.

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Pharmacists' experiences and perceptions about simulation use for learning and development of clinical skills in Kuwait

Katoue, M. G. & Ker, J., Dec 2019, In: International Journal of Clinical Pharmacy. 41, 6, p. 1451-1461 11 p.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Pharmacists Attitudes and Role in Diabetes Management in Kuwait

Al-Haqan, A. A., Al-Taweel, D., Awad, A. & Wake, D., May 2017, In: Medical Principles and Practice: International Journal of the Kuwait University Health Science Centre. 26, 3, p. 273-279 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

8 Citations (Scopus)

176 Downloads (Pure)

Pharmacist-led management of chronic pain in primary care: costs and benefits in a pilot randomised controlled trial

Neilson, A. R., Bruhn, H., Bond, C. M., Elliott, A. M., Smith, B. H., Hannaford, P. C., Holland, R., Lee, A. J., Watson, M., Wright, D. & McNamee, P., 1 Apr 2015, In: BMJ Open. 5, 4, 11 p., e006874.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Pharmacist-led management of chronic pain in primary care: results from a randomised controlled exploratory trial

Bruhn, H., Bond, C. M., Elliott, A. M., Hannaford, P. C., Lee, A. J., McNamee, P., Smith, B. H., Watson, M. C., Holland, R. & Wright, D., 2013, In: BMJ Open. 3, 4, e002361.

Research output: Contribution to journal › Article › peer-review

56 Citations (Scopus)

Pharmacist and Data-driven Quality Improvement in Primary Care (P-DQIP): A qualitative study of anticipated implementation factors informed by the Theoretical Domains Framework

Tang, J., Toma, M., Gray, N. M., Delvaux, J., Guthrie, B., Grant, A., Duncan, E. M. & Dreischulte, T., 28 Feb 2020, In: BMJ Open. 10, 2, 16 p., e033574.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2 Citations (Scopus)

16 Downloads (Pure)

Pharmaceutical products liability: 30 years of law reform?

Ferguson, P. R., 1992, In: Juridical Review: the Law Journal of the Scottish Universities. p. 226-241

Research output: Contribution to journal › Article › peer-review

Pharmaceutical care of older people: What do older people want from community pharmacy?

Wood, K., Gibson, F., Radley, A. & Williams, B., Apr 2015, In: International Journal of Pharmacy Practice. 23, 2, p. 121-130 10 p.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Pharamcological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in LDLR-/- mouse model of atherosclerosis

Thompson, D., Morrice, N., Grant, L., Lees, E. K., Mody, N., Wilson, H. & Delibegovic, M., 29 Sep 2017, In: Clinical Science. 131, 20, p. 2489-2501

Research output: Contribution to journal › Article › peer-review

Open Access

File

12 Citations (Scopus)

39 Downloads (Pure)

Phage shock protein PspA of Escherichia coli relieves saturation of protein export via the Tat pathway

DeLisa, M. P., Lee, P., Palmer, T. & Georgiou, G., 2004, In: Journal of Bacteriology. 186, 2, p. 366-373 8 p.

Research output: Contribution to journal › Article › peer-review

123 Citations (Scopus)

Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21^WAF1

Burch, L. R., Scott, M., Pohler, E., Meek, D. & Hupp, T., 12 Mar 2004, In: Journal of Molecular Biology. 337, 1, p. 115-128 14 p.

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Phaeochromocytomas associated with PTEN mutation demonstarate tissue specificity in the anti-tumour effect of mTOR inhibition

Taggart, C. & Fleming, S., Sep 2012, In: Journal of Pathology. 228, Suppl. 1, p. S37-S37 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

PGI₂-induced activation and sensitization of articular mechanonociceptors

Birrell, G. J., McQueen, D. S., Iggo, A., Coleman, R. A. & Grubb, B. D., 11 Mar 1991, In: Neuroscience Letters. 124, 1, p. 5-8 4 p.

Research output: Contribution to journal › Article › peer-review

79 Citations (Scopus)

PGE2 induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway

Mackenzie, K. F., Clark, K., Naqvi, S., McGuire, V. A., Nöehren, G., Kristariyanto, Y., van den Bosch, M., Mudaliar, M., McCarthy, P. C., Pattison, M. J., Pedrioli, P. G. A., Barton, G. J., Toth, R., Prescott, A. & Arthur, J. S. C., 15 Jan 2013, In: Journal of Immunology. 190, 2, p. 565-577 13 p.

Research output: Contribution to journal › Article › peer-review

135 Citations (Scopus)

PGC-1 alpha increases PDH content but does not change acute PDH regulation in mouse skeletal muscle

Kiilerich, K., Adser, H., Jakobsen, A. H., Pedersen, P. A., Hardie, D. G., Wojtaszewski, J. F. P. & Pilegaard, H., Nov 2010, In: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology (AJP - Regulatory, Integrative and Comparative Physiology) . 299, 5, p. R1350-R1359 10 p.

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Filters for Research Outputs

Search results