Find Research outputs

Search results

• p53-dependent repression of polo-like kinase-1 (PLK1)

  McKenzie, L., King, S., Marcar, L., Nicol, S., Dias, S., Schumm, K., Robertson, P., Bourdon, J-C., Perkins, N., Fuller-Pace, F. & Meek, D. W., 15 Oct 2010, In: Cell Cycle. 9, 20, p. 4200-4212 13 p.

  Research output: Contribution to journal › Article › peer-review
  95 Citations (Scopus)

• P53 Dependent Repression of PLK1

  King, S. & Meek, D., Sep 2010, In: Journal of Pathology. 222, p. S31-S31 1 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• p53 controls expression of the DNA deaminase APOBEC₃B to limit its potential mutagenic activity in cancer cells

  Periyasamy, M., Singh, A. K., Gemma, C., Kranjec, C., Farzan, R., Leach, D. A., Navaratnam, N., Pálinkás, H. L., Vértessy, B. G., Fenton, T. R., Doorbar, J., Fuller-Pace, F., Meek, D. W., Coombes, R. C., Buluwela, L. & Ali, S., 2 Nov 2017, In: Nucleic Acids Research. 45, 19, p. 11056-11069 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  50 Citations (Scopus)

  198 Downloads (Pure)

• p53 codon 72 ARG/PRO polymorphism is not related to HPV type or lesion grade in low- and high-grade squamous intra-epithelial lesions and invasive squamous carcinoma of the cervix

  Giannoudis, A., Graham, D. A., Southern, S. A. & Herrington, C. S., 1999, In: International Journal of Cancer. 83, 1, p. 66-69 4 p.

  Research output: Contribution to journal › Article › peer-review
  47 Citations (Scopus)

• p53 beta isoform modulates differentially p53 transcriptional activity in response to stress

  Fernandes, K. & Bourdon, J. C., 2008, In: Breast Cancer Research. 10, p. S9-S9 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• p53-Based cyclotherapy: exploiting the 'guardian of the genome' to protect normal cells from cytotoxic therapy

  Rao, B., Lain, S. & Thompson, A. M., 10 Dec 2013, In: British Journal of Cancer. 109, 12, p. 2954-2958 5 p.

  Research output: Contribution to journal › Article › peer-review
  46 Citations (Scopus)

• p53 as a therapeutic target

  Staples, O. D., Steele, R. J. C. & Lain, S., Aug 2008, In: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6, 4, p. 240-243 4 p.

  Research output: Contribution to journal › Review article › peer-review
  20 Citations (Scopus)

• p53 Antigen in cervical condylomata, intraepithelial neoplasia, and carcinoma: relationship to HPV infection and integration

  Cooper, K., Herrington, C. S., Evans, M. F., Gatter, K. C. & McGee, J. OD., Sep 1993, In: Journal of Pathology. 171, 1, p. 27-34 8 p.

  Research output: Contribution to journal › Article › peer-review
  35 Citations (Scopus)

• p53- and Mdm2-independent repression of NF-kappa B transactivation by the ARF tumor suppressor

  Rocha, S., Campbell, K. J. & Perkins, N. D., Jul 2003, In: Molecular Cell. 12, 1, p. 15-25 11 p.

  Research output: Contribution to journal › Article › peer-review
  176 Citations (Scopus)

• p53 and Mdm2: not all cells are equal

  Coates, P. J., Dec 2007, In: Journal of Pathology. 213, 4, p. 357-9 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  6 Citations (Scopus)

• p53 and its isoforms in cancer

  Bourdon, J-C., 31 Jul 2007, In: British Journal of Cancer. 97, 3, p. 277-282 6 p.

  Research output: Contribution to journal › Review article › peer-review
  178 Citations (Scopus)

• p53 and immunity

  Narayan, V., Meek, S. E. M. & Ball, K., 2010, p53. Ayed, A. & Hupp, T. (eds.). Austin, TX: Landes Bioscience, p. 178-186 9 p. (Molecular Biology Intelligence Unit; vol. 1).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)

• p53 and gamma radiation in the normal breast

  Liu, Y., Appleyard, M. V. C. L., Coates, P. J. & Thompson, A. M., 2009, In: International Journal of Radiation Biology. 85, 11, p. 1026-1031 6 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia

  Groves, M. J., Johnson, C. E., James, J., Prescott, A. R., Cunningham, J., Haydock, S., Pepper, C., Fegan, C., Pirrie, L., Westwood, N. J., Coates, P. J., Ganley, I. G. & Tauro, S., 2013, In: British Journal of Cancer. 109, October, p. 2432=2444 13 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer

  Marcel, V., Ghayad, S. E., Belin, S., Therizols, G., Morel, A-P., Solano-Gonzàlez, E., Vendrell, J. A., Hacot, S., Mertani, H. C., Albaret, M. A., Bourdon, J-C., Jordan, L., Thompson, A., Tafer, Y., Cong, R., Bouvet, P., Saurin, J-C., Catez, F., Prats, A-C., Puisieux, A., & 1 othersDiaz, J-J., 9 Sep 2013, In: Cancer Cell. 24, 3, p. 318-330 13 p.

  Research output: Contribution to journal › Article › peer-review
  186 Citations (Scopus)

• p53 activating benzoyl urea and benzoyl thiourea compounds

  Lain, S., Lane, D., Stark, M. J. R., McCarthy, A. R., Hollick, J. J. & Westwood, N. J., 13 Mar 2008, IPC No. A61K31/17, Patent No. WO2008029096

  Research output: Patent

• P53 abnormalities and outcomes in colorectal cancer: a systematic review

  Munro, A. J., Lain, S. & Lane, D. P., Feb 2005, In: British Journal of Cancer. 92, 3, p. 434-444 11 p.

  Research output: Contribution to journal › Article › peer-review
  246 Citations (Scopus)

• p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress

  Murray-Zmijewski, F., Lane, D. & Bourdon, J-C., Jun 2006, In: Cell Death & Differentiation. 13, 6, p. 962-972 11 p.

  Research output: Contribution to journal › Review article › peer-review
  410 Citations (Scopus)

• p53: 25 years of research and more questions to answer

  Bourdon, J. C., De Laurenzi, V., Melino, G. & Lane, D., 2003, In: Cell Death & Differentiation. 10, 4, p. 397-399 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  59 Citations (Scopus)

• P50 addressing the vocational development of young people with long-term health conditions in health care settings: a systematic review and mixed methods synthesis

  Farre, A., Lunt, L., Lee, R. R., Verstappen, S. & McDonagh, J. E., Oct 2022, In: Rheumatology Advances in Practice. 6, Supplement 1, p. i49-i51 3 p., rkac067.050.

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access

  File

• p42 map kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A₁ Implications for Alzheimer's disease

  Goedert, M., Cohen, E. S., Jakes, R. & Cohen, P., 2 Nov 1992, In: FEBS Letters. 312, 1, p. 95-99 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  260 Citations (Scopus)

• P3OO and smooth eye pursuit: concordance of abnormalities and relation to clinical features in DSM-III schizophrenia

  Ebmeier, E. K. P., Potter, D. D., Cochrane, R. H. B., Mackenzie, A. R., McAllister, H., Besson, J. A. O. & Salzen, E. A., 1990, In: Acta Psychiatrica Scandinavica. 82, 4, p. 283-288 6 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

  Sabio, G., Arthur, J. S. C., Kuma, Y., Peggie, M., Carr, J., Murray-Tait, V., Centeno, F., Goedert, M., Morrice, N. A. & Cuenda, A., 23 Mar 2005, In: EMBO Journal. 24, 6, p. 1134-1145 12 p.

  Research output: Contribution to journal › Article › peer-review
  193 Citations (Scopus)

• P38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

  Risco, A., Del Dresno, C., Mambol, A., Alsina-Beauchamp, D., MacKenzie, K. F., Yang, H-T., Barber, D. F., Morcelle, C., Arthur, J. S. C., Ley, S. C., Ardavin, C. F. & Cuenda, A., 10 Jul 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11200-11205 6 p.

  Research output: Contribution to journal › Article › peer-review
  87 Citations (Scopus)

• p38α regulates cytokine-induced IFNγ secretion via the Mnk1/eIF4E pathway in Th1 cells

  Salvador-Bernáldez, M., Mateus, S. B., Del Barco Barrantes, I., Arthur, S. C., Martínez-A, C., Nebreda, A. R. & Salvador, J. M., 14 Jun 2017, In: Immunology and Cell Biology. 95, p. 814-823 10 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• p38 MAPK signalling regulates cytokine production in IL-33 stimulated Type 2 Innate Lymphoid cells

  Petrova, T., Pesic, J., Pardali, K., Gaestel, M. & Arthur, J. S. C., 26 Feb 2020, In: Scientific Reports. 10, 15 p., 3479.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  15 Citations (Scopus)

  67 Downloads (Pure)

• p38 MAPK regulates COPII recruitment

  Wang, L. & Lucocq, J. M., 16 Nov 2007, In: Biochemical and Biophysical Research Communications. 363, 2, p. 317-21 5 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• p38 MAP-kinases pathway regulation, function and role in human diseases

  Cuenda, A. & Rousseau, S., Aug 2007, In: BBA - General Subjects. 1773, 8, p. 1358-75 18 p.

  Research output: Contribution to journal › Article › peer-review
  996 Citations (Scopus)

• p38^MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex

  Tiedje, C., Lubas, M., Tehrani, M., Menon, M. B., Ronkina, N., Rousseau, S., Cohen, P., Kotlyarov, A. & Gaestel, M., Feb 2015, In: RNA: a Publication of the RNA Society. 21, 2, p. 262-278 17 p.

  Research output: Contribution to journal › Article

  Open Access
  29 Citations (Scopus)

• p38 gamma regulates interaction of nuclear PSF and RNA with the tumour-suppressor hDlg in response to osmotic shock

  Sabio, G., Cerezo-Guisado, M. I., del Reino, P., Inesta-Vaquera, F. A., Rousseau, S., Arthur, J. S. C., Campbell, D. G., Centeno, F. & Cuenda, A., 1 Aug 2010, In: Journal of Cell Science. 123, 15, p. 2596-2604 9 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• p38 delta mitogen-activated protein kinase Is essential for skin tumor development in mice

  Schindler, E. M., Hindes, A., Gribben, E. L., Burns, C. J., Yin, Y., Lin, M-H., Owen, R. J., Longmore, G. D., Kissling, G. E., Arthur, J. S. C. & Efimova, T., 1 Jun 2009, In: Cancer Research. 69, 11, p. 4648-4655 8 p.

  Research output: Contribution to journal › Article › peer-review
  65 Citations (Scopus)

• P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment

  Wada, M., Canals, D., Adada, M., Coant, N., Salama, M. F., Helke, K. L., Arthur, J. S., Shroyer, K. R., Kitatani, K., Obeid, L. M. & Hannun, Y. A., 23 Nov 2017, In: Oncogene. 36, p. 6649-6657 9 p.

  Research output: Contribution to journal › Article › peer-review
  48 Citations (Scopus)

• p38 alpha and p38 beta mitogen-activated protein kinases determine cholinergic transdifferentiation of sympathetic neurons

  Loy, B., Apostolova, G., Dorn, R., McGuire, V. A., Arthur, J. S. C. & Dechant, G., 24 Aug 2011, In: Journal of Neuroscience. 31, 34, p. 12059-12067 9 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• p38 alpha- and DYRK1A-dependent phosphorylation of caspase-9 at an inhibitory site in response to hyperosmotic stress

  Seifert, A. & Clarke, P. R., Nov 2009, In: Cellular Signalling. 21, 11, p. 1626-1633 8 p.

  Research output: Contribution to journal › Article › peer-review
  43 Citations (Scopus)

• p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient

  Hazzalin, C. A., Cano, E., Cuenda, A., Barratt, M. J., Cohen, P. & Mahadevan, L. C., Aug 1996, In: Current Biology. 6, 8, p. 1028-1031 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  202 Citations (Scopus)

• p34cdc2 phosphorylation sites in histone H1 are dephosphorylated by protein phosphatase 2A₁

  Sola, M. M., Langan, T. & Cohen, P., 3 Sep 1991, In: BBA - Molecular Cell Research. 1094, 2, p. 211-216 6 p.

  Research output: Contribution to journal › Article › peer-review
  56 Citations (Scopus)

• P300 transcriptional repression is mediated by SUMO modification

  Girdwood, D., Bumpass, D., Vaughan, O. A., Thain, A., Anderson, L. A., Snowden, A. W., Garcia-Wilson, E., Perkins, N. D. & Hay, R. T., Apr 2003, In: Molecular Cell. 11, 4, p. 1043-1054 12 p.

  Research output: Contribution to journal › Article › peer-review
  381 Citations (Scopus)

• p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes

  Genot, E., Reif, K., Beach, S., Kramer, I. & Cantrell, D., 1 Oct 1998, In: Oncogene. 17, 13, p. 1731-1738 8 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• p21^ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes

  Izquierdo, M., Leevers, S. J., Marshall, C. J. & Cantrell, D., 1 Oct 1993, In: Journal of Experimental Medicine. 178, 4, p. 1199-1208 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  152 Citations (Scopus)

• p21^ras and calcineurin synergize to regulate the nuclear factor of activated T cells

  Woodrow, M., Clipstone, N. A. & Cantrell, D., 1 Nov 1993, In: Journal of Experimental Medicine. 178, 5, p. 1517-1522 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  122 Citations (Scopus)

• p21-LacZ reporter mice reflect p53-dependent toxic insult

  Vasey, D. B., Wolf, C. R., MacArtney, T., Brown, K. & Whitelaw, C. B. A., 15 Mar 2008, In: Toxicology and Applied Pharmacology. 227, 3, p. 440-450 11 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• P215 Left Ventricular Hypertrophy in Chronic Obstructive Pulmonary Disease Without Hypoxaemia: The Elephant in the Room?

  Anderson, W., Lipworth, B., Rekhraj, S., Struthers, A. & George, J., 1 Dec 2012, In: Thorax. 67, Suppl 2, p. A158.1-A158

  Research output: Contribution to journal › Conference article › peer-review

• p21(ras) mediates control of IL-2 gene promoter function in T cell activation

  Rayter, S. I., Woodrow, M., Lucas, S. C., Cantrell, D. A. & Downward, J., 1 Jan 1992, In: EMBO Journal. 11, 12, p. 4549-4556 8 p.

  Research output: Contribution to journal › Article › peer-review

  149 Citations (Scopus)

• p21(ras) function is important for T cell antigen receptor and protein kinase C regulation of nuclear factor of activated T cells

  Woodrow, M. A., Rayter, S., Downward, J. & Cantrell, D. A., 1 May 1993, In: Journal of Immunology. 150, 9, p. 3853-3861 9 p.

  Research output: Contribution to journal › Article › peer-review

  80 Citations (Scopus)

• P200 Deep brain stimulation of the mammilothalamic tract for the treatment of refractory epilepsy

  Javed, S., Khan, S., Sharples, P., Lhatoo, S., Carter, M. & Gill, S., Sep 2009, p. 82. 1 p.

  Research output: Contribution to conference › Abstract › peer-review

• P175 Work Ready Champions for Young People: the role of occupational therapy in addressing the pre-vocational and early-employment needs of young people with long term health conditions

  Hackett, J., Lunt, L., Pidgeon, C., Farre, A. & McDonagh, J., 23 Apr 2022, In: Rheumatology. 61, Suppl 1, p. i101-i102 2 p., P175.

  Research output: Contribution to journal › Conference article › peer-review

  Open Access

  File
  16 Downloads (Pure)

• P 174 - Analysis of vertical ground reaction force and vertical centre of mass movement following total hip replacement

  Kristensena, A., Gibbs, S., Raza, W., Arnold, G., Abboud, R. & Wang, W., Sep 2018, In: Gait and Posture. 65 Suppl 1, p. 528-529 2 p.

  Research output: Contribution to journal › Article › peer-review

• p16 status and interval neck dissection findings after a 'clinically complete response' to chemoradiotherapy in oropharyngeal squamous cell carcinoma

  Miah, M. S., Spielmann, P., White, S. J., Kennedy, C., Kernohan, N., Mountain, R. E., Cassasola, R. & Mahendran, S., Aug 2015, In: Journal of Laryngology and Otology. 129, 8, p. 801-806 6 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• P16INK4a and p14ARF tumor suppressor genes are commonly inactivated in cutaneous squamous cell carcinoma

  Brown, V. L., Harwood, C. A., Crook, T., Cronin, J. G., Kelsell, D. P. & Proby, C. M., 2004, In: Journal of Investigative Dermatology. 122, 5, p. 1284-1292 9 p.

  Research output: Contribution to journal › Article › peer-review
  129 Citations (Scopus)

• p16(INK4a) immunohistochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia

  Klaes, R., Benner, A., Friedrich, T., Ridder, R., Herrington, S., Jenkins, D., Kurman, R. J., Schmidt, D., Stoler, M. & Doeberitz, M. V. K., Nov 2002, In: American Journal of Surgical Pathology. 26, 11, p. 1389-1399 11 p.

  Research output: Contribution to journal › Article › peer-review
  398 Citations (Scopus)